Result of FASTA (omim) for
pFN21AE1991
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1991, 569 aa
1>>>pF1KE1991 569 - 569 aa - 569 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1951+/-0.000349; mu= 20.5527+/- 0.022
mean_var=88.3583+/-16.952, 0's: 0 Z-trim(117.1): 154 B-trim: 89 in 1/49
Lambda= 0.136443
statistics sampled from 28589 (28799) to 28589 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.338), width: 16
Scan time: 9.810
The best scores are: opt bits E(85289)
NP_110414 (OMIM: 608593,614809) complement factor ( 569) 4094 816.1 0
XP_011508322 (OMIM: 608593,614809) PREDICTED: comp ( 572) 3977 793.0 0
NP_000177 (OMIM: 126700,134370,235400,609814,61069 (1231) 1661 337.5 1.6e-91
NP_001188480 (OMIM: 605337) complement factor H-re ( 577) 1370 279.9 1.6e-74
NP_001188479 (OMIM: 605337) complement factor H-re ( 578) 1317 269.4 2.2e-71
XP_006711192 (OMIM: 605337) PREDICTED: complement ( 570) 1316 269.2 2.5e-71
NP_002104 (OMIM: 134371,235400,603075) complement ( 330) 1133 233.0 1.2e-60
XP_011507586 (OMIM: 134580,613235) PREDICTED: coag ( 675) 939 195.1 6.2e-49
NP_005657 (OMIM: 600889) complement factor H-relat ( 270) 929 192.7 1.3e-48
XP_011507760 (OMIM: 600889) PREDICTED: complement ( 266) 925 191.9 2.2e-48
XP_011507588 (OMIM: 134580,613235) PREDICTED: coag ( 628) 924 192.1 4.5e-48
NP_001985 (OMIM: 134580,613235) coagulation factor ( 661) 924 192.1 4.7e-48
XP_011507585 (OMIM: 134580,613235) PREDICTED: coag ( 676) 924 192.1 4.8e-48
XP_016855603 (OMIM: 605337) PREDICTED: complement ( 387) 877 182.6 2e-45
XP_016855599 (OMIM: 605337) PREDICTED: complement ( 519) 861 179.6 2.1e-44
XP_011507761 (OMIM: 600889) PREDICTED: complement ( 250) 851 177.3 5e-44
NP_006675 (OMIM: 605337) complement factor H-relat ( 331) 719 151.5 4e-36
NP_001160096 (OMIM: 235400,603075,605336) compleme ( 269) 710 149.6 1.2e-35
XP_011507759 (OMIM: 134371,235400,603075) PREDICTE ( 265) 685 144.7 3.6e-34
NP_066303 (OMIM: 235400,603075,605336) complement ( 330) 684 144.6 4.8e-34
XP_005245170 (OMIM: 600889) PREDICTED: complement ( 205) 638 135.3 1.8e-31
XP_016856598 (OMIM: 600889) PREDICTED: complement ( 211) 629 133.6 6.3e-31
XP_011507762 (OMIM: 600889) PREDICTED: complement ( 201) 627 133.2 8e-31
NP_001299601 (OMIM: 600889) complement factor H-re ( 146) 563 120.4 4e-27
XP_011533056 (OMIM: 608397) PREDICTED: CUB and sus (2238) 475 104.2 4.5e-21
XP_011533055 (OMIM: 608397) PREDICTED: CUB and sus (2595) 475 104.3 5e-21
XP_011533054 (OMIM: 608397) PREDICTED: CUB and sus (3549) 475 104.4 6.3e-21
NP_150094 (OMIM: 608397) CUB and sushi domain-cont (3564) 475 104.4 6.3e-21
XP_016869220 (OMIM: 608397) PREDICTED: CUB and sus (3327) 474 104.2 6.8e-21
XP_011515117 (OMIM: 608399) PREDICTED: CUB and sus (2173) 471 103.4 7.6e-21
XP_016868501 (OMIM: 608399) PREDICTED: CUB and sus (3463) 471 103.6 1.1e-20
XP_016868500 (OMIM: 608399) PREDICTED: CUB and sus (3507) 471 103.6 1.1e-20
NP_443132 (OMIM: 608399) CUB and sushi domain-cont (3538) 471 103.7 1.1e-20
XP_016868499 (OMIM: 608399) PREDICTED: CUB and sus (3577) 471 103.7 1.1e-20
XP_011515118 (OMIM: 608399) PREDICTED: CUB and sus (3603) 471 103.7 1.1e-20
XP_016868498 (OMIM: 608399) PREDICTED: CUB and sus (3637) 471 103.7 1.1e-20
NP_937757 (OMIM: 608399) CUB and sushi domain-cont (3667) 471 103.7 1.1e-20
XP_016868497 (OMIM: 608399) PREDICTED: CUB and sus (3681) 471 103.7 1.1e-20
NP_937756 (OMIM: 608399) CUB and sushi domain-cont (3707) 471 103.7 1.1e-20
XP_016855678 (OMIM: 608398) PREDICTED: CUB and sus (3506) 470 103.5 1.2e-20
XP_016855676 (OMIM: 608398) PREDICTED: CUB and sus (3606) 470 103.5 1.3e-20
XP_016855674 (OMIM: 608398) PREDICTED: CUB and sus (3607) 470 103.5 1.3e-20
XP_016855675 (OMIM: 608398) PREDICTED: CUB and sus (3607) 470 103.5 1.3e-20
NP_001268885 (OMIM: 608398) CUB and sushi domain-c (3631) 470 103.5 1.3e-20
XP_016855602 (OMIM: 605337) PREDICTED: complement ( 458) 448 98.3 5.8e-20
XP_016855601 (OMIM: 605337) PREDICTED: complement ( 468) 448 98.3 5.9e-20
XP_016855600 (OMIM: 605337) PREDICTED: complement ( 519) 448 98.3 6.4e-20
NP_443128 (OMIM: 608398) CUB and sushi domain-cont (3487) 457 100.9 7.2e-20
NP_001014975 (OMIM: 126700,134370,235400,609814,61 ( 449) 415 91.8 5.2e-18
XP_016856597 (OMIM: 126700,134370,235400,609814,61 ( 446) 413 91.4 6.8e-18
>>NP_110414 (OMIM: 608593,614809) complement factor H-re (569 aa)
initn: 4094 init1: 4094 opt: 4094 Z-score: 4356.9 bits: 816.1 E(85289): 0
Smith-Waterman score: 4094; 100.0% identity (100.0% similar) in 569 aa overlap (1-569:1-569)
10 20 30 40 50 60
pF1KE1 MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 SPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 QNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RVGSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 RVGSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNPN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 FIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YAMIGNNMITCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 YAMIGNNMITCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DIFRYRHSVCINGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 DIFRYRHSVCINGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 YLLPEAKEIVCKDGRWQSLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 YLLPEAKEIVCKDGRWQSLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 FYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 FYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQ
490 500 510 520 530 540
550 560
pF1KE1 CKFPHKAMISSPPFRAICQEGKFEYPICE
:::::::::::::::::::::::::::::
NP_110 CKFPHKAMISSPPFRAICQEGKFEYPICE
550 560
>>XP_011508322 (OMIM: 608593,614809) PREDICTED: compleme (572 aa)
initn: 3977 init1: 3977 opt: 3977 Z-score: 4232.4 bits: 793.0 E(85289): 0
Smith-Waterman score: 3977; 100.0% identity (100.0% similar) in 550 aa overlap (20-569:23-572)
10 20 30 40 50
pF1KE1 MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEY
::::::::::::::::::::::::::::::::::::::
XP_011 MVKPLRQKRNQENVVFHRPCEAGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 NFVSPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFVSPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 YSLQNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSLQNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 NLIRVGSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLIRVGSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDC
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 NPNFIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPNFIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNC
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE1 RNEYAMIGNNMITCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNEYAMIGNNMITCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRY
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE1 RCSDIFRYRHSVCINGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCSDIFRYRHSVCINGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLC
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE1 KENYLLPEAKEIVCKDGRWQSLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KENYLLPEAKEIVCKDGRWQSLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYR
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE1 CQSFYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQSFYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAV
490 500 510 520 530 540
540 550 560
pF1KE1 EFQCKFPHKAMISSPPFRAICQEGKFEYPICE
::::::::::::::::::::::::::::::::
XP_011 EFQCKFPHKAMISSPPFRAICQEGKFEYPICE
550 560 570
>>NP_000177 (OMIM: 126700,134370,235400,609814,610698) c (1231 aa)
initn: 2082 init1: 1465 opt: 1661 Z-score: 1764.3 bits: 337.5 E(85289): 1.6e-91
Smith-Waterman score: 1661; 46.2% identity (70.9% similar) in 519 aa overlap (53-566:475-981)
30 40 50 60 70 80
pF1KE1 CDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCTEEGWSPTPK
:.:. ..:. . ::: ..::: :
NP_000 VKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPT
450 460 470 480 490 500
90 100 110 120 130 140
pF1KE1 CLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGY--SLQNNEKNISCVERGWSTPPIC
:.. :..: :...... .::.. :. :: . .. .: : ::: :::
NP_000 CIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPIC
510 520 530 540 550 560
150 160 170 180 190 200
pF1KE1 SFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFGWSPNFPT
. . ::..: ..... . ::..::::.::::::. .. :: .:::::.:: ::..:
NP_000 -YER-ECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPI
570 580 590 600 610 620
210 220 230 240 250 260
pF1KE1 CKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVDGEWTTLP
:: ::.::::::.: ::.::: ::::::.::::: ::: :...::.:::::::::::::
NP_000 CKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDGEWTTLP
630 640 650 660 670 680
270 280 290 300 310 320
pF1KE1 TCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITCINGIWTELP
.:. . .::: :::::.:..: : ::: .: ::: :: . ..:::. ::::.:.::.::
NP_000 VCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLP
690 700 710 720 730 740
330 340 350 360 370 380
pF1KE1 MCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCSDIFRYRHSVCINGKWNPEVD
.::: .::.:: ... : . :::.::: ::::: . :.:::::.:.:::.
NP_000 QCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVN
750 760 770 780 790 800
390 400 410 420 430 440
pF1KE1 CTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKDGRWQSLP
:. . :.:::::::::..:::::.::.:::::.:::.::::. :..::.::::::::.:
NP_000 CSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRWQSIP
810 820 830 840 850 860
450 460 470 480 490
pF1KE1 RCVESTAYCGPPPSINNGDTTSFPLS--VYPPGSTVTYRCQSFYKLQGSVTVTCRNKQWS
:::. :. ::.:..: .: : : :. ..: :.. .... .:: .::
NP_000 LCVEKIP-CSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWS
870 880 890 900 910 920
500 510 520 530 540 550
pF1KE1 EPPRCLD-PCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSPPFRAI
::.: :: : . .. .:. : :. : ..: : . :..: . :
NP_000 SPPQCEGLPCKSPPEISHGVVAHM---SDSYQY---GEEVTYKC-FEGFG-IDGPAI-AK
930 940 950 960 970
560
pF1KE1 CQEGKFEYPICE
: :. .:
NP_000 CLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTC
980 990 1000 1010 1020 1030
>--
initn: 884 init1: 631 opt: 713 Z-score: 755.8 bits: 150.8 E(85289): 2.3e-35
Smith-Waterman score: 713; 38.8% identity (65.9% similar) in 255 aa overlap (320-568:982-1228)
290 300 310 320 330 340
pF1KE1 GVSVEVNCRNEYAMIGNNMITCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKE-
: :. : : .. .... . .. :.
NP_000 GEEVTYKCFEGFGIDGPAIAKCLGEKWSHPPSCIKTD----C-LSLPSFENAIPMGEKKD
960 970 980 990 1000
350 360 370 380 390 400
pF1KE1 -FNHNSRIRYRCSDIFRY---RHSVCINGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTT
.. . .. : :. ... . .:::..:. . : :. : :: . :: ..
NP_000 VYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTC---RDTSCVNPPTVQNAYIVSRQ
1010 1020 1030 1040 1050 1060
410 420 430 440 450 460
pF1KE1 VN-YQDGEKVAVLCKENYLLPEAKEIVCKDGRWQSLPRCVESTAYCGPPPSINNGDTTSF
.. : .::.: :. : . .:..: .: : :.: .::. ::::: :.::: :::
NP_000 MSKYPSGERVRYQCRSPYEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSF
1070 1080 1090 1100 1110 1120
470 480 490 500 510 520
pF1KE1 PLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENMNKNNIQLKW
::::: :.:.: :.::..:.:.:. .:::: ::::::.:: :::.:.: :.. :: :.:
NP_000 PLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRW
1130 1140 1150 1160 1170 1180
530 540 550 560
pF1KE1 RNDGKLYAKTGDAVEFQCKFPHKAMISSPPFRAICQEGKFEYPICE
:::..::..::: :: .. : .:. : .::.::: :
NP_000 TAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR
1190 1200 1210 1220 1230
>--
initn: 475 init1: 413 opt: 413 Z-score: 436.6 bits: 91.8 E(85289): 1.4e-17
Smith-Waterman score: 413; 39.8% identity (70.3% similar) in 118 aa overlap (23-140:325-442)
10 20 30 40 50
pF1KE1 MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFY
::.: :.:: :: :. :. : .:. .
NP_000 RNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYS
300 310 320 330 340 350
60 70 80 90 100 110
pF1KE1 YSCEYNFVSPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQI
: :. .: .:: :.: .: ::..::::. ::: : ::...::.... : ..: ....
NP_000 YYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDV
360 370 380 390 400 410
120 130 140 150 160 170
pF1KE1 ICNTGYSLQNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKVGDVLK
:. ::.: . . ...:.: ::: : :
NP_000 ACHPGYALPKAQTTVTCMENGWSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAK
420 430 440 450 460 470
>>NP_001188480 (OMIM: 605337) complement factor H-relate (577 aa)
initn: 1182 init1: 629 opt: 1370 Z-score: 1458.9 bits: 279.9 E(85289): 1.6e-74
Smith-Waterman score: 1370; 36.5% identity (62.4% similar) in 595 aa overlap (1-569:1-577)
10 20 30 40 50 60
pF1KE1 MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFV
::::..::: ::: ..:. ::::.:.:: :: . . . .:. . : :. :::
NP_001 MLLLINVILTLWVSCANGQVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFV
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 SPSKSFWTRITCTEEGWSPTPKCLRMCSFP--FVKNGHSESSGLIHLEGDTVQIICNTGY
.:: :.: : ::..::::: ::: :: ..:: :. :.. .. .: :. ::
NP_001 TPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDVEIENGFISESSSIYILNEETQYNCKPGY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 SLQ--NNEKNISCVERGWSTPPIC-SFTKGECHVPILEANVDAQPKKESYKVGDVLKFSC
. :. .:.:.. :::: ::: .: : .:..: : :. . .:. :.: . :
NP_001 ATAEGNSSGSITCLQNGWSTQPICIKF----CDMPVFE-NSRAKSNGMWFKLHDTLDYEC
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 RKNL-IRVG--SDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEV
. : .::. : . ::: ..::: .. ..::::: .:::.. . .. :
NP_001 YDGYESSYGNTTDSIVCGEDGWS-HLPTCYNSSENCGPPPPISNGDTTSFPQKVYLPWSR
180 190 200 210 220 230
240 250 260 270 280
pF1KE1 VEYDCNPNFIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPELEYG--YVQPSVPPY---
:::.:. . ..: : . : .:.:. : :. ..: : . ::...: : . . ::
NP_001 VEYQCQSYYELQGSKYVTCSNGDWSEPPRCI-SMKPCEF-PEIQHGHLYYENTRRPYFPV
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 QHGVSVEVNCRNEYAMIGN---NMITCINGIWTELPMCVATHQLKRCKIAGVNIKT-LLK
: : : .... .. ..: : . : : :. :. . ..:.. ...
NP_001 ATGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWLPTVPC-----LRTCSKSDIEIENGFIS
300 310 320 330 340
350 360 370 380 390
pF1KE1 LSGKEFNHNSRIRYRCSDIFRYRHS------VCINGKWNPEVDCTEKREQFCPPPPQIPN
:.. . :..:.:.:. . . .:... :. . : .:: : . :
NP_001 ESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICI----KFCDMPV-FEN
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE1 AQNMTTTVNYQDGEKVAVLCKENYLLPEAKE---IVCKDGRWQSLPRCVESTAYCGPPPS
.. .. . .. . . : ..: . .. ::: . :. .: : .:. :::::
NP_001 SRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPP
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE1 INNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENM
:.::::::: :.:: : : : :.:::.:.:::: ::: : .:::::::. ::...::::
NP_001 ISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENM
470 480 490 500 510 520
520 530 540 550 560
pF1KE1 NKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSPPFRAICQEGKFEYPICE
:::::::: ..: : ::::::..::.::. ..: : :.:.:.:: ::: ::
NP_001 NKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRCE
530 540 550 560 570
>>NP_001188479 (OMIM: 605337) complement factor H-relate (578 aa)
initn: 1055 init1: 629 opt: 1317 Z-score: 1402.5 bits: 269.4 E(85289): 2.2e-71
Smith-Waterman score: 1362; 36.6% identity (62.2% similar) in 596 aa overlap (1-569:1-578)
10 20 30 40 50
pF1KE1 MLLLFSVILISWVSTVGG-EGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNF
::::..::: ::: ..: : ::::.:.:: :: . . . .:. . : :. ::
NP_001 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 VSPSKSFWTRITCTEEGWSPTPKCLRMCSFP--FVKNGHSESSGLIHLEGDTVQIICNTG
:.:: :.: : ::..::::: ::: :: ..:: :. :.. .. .: :. :
NP_001 VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDVEIENGFISESSSIYILNEETQYNCKPG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 YSLQ--NNEKNISCVERGWSTPPIC-SFTKGECHVPILEANVDAQPKKESYKVGDVLKFS
:. :. .:.:.. :::: ::: .: : .:..: : :. . .:. :.: .
NP_001 YATAEGNSSGSITCLQNGWSTQPICIKF----CDMPVFE-NSRAKSNGMWFKLHDTLDYE
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 CRKNL-IRVG--SDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNE
: . : .::. : . ::: ..::: .. ..::::: .:::.. . .. :
NP_001 CYDGYESSYGNTTDSIVCGEDGWS-HLPTCYNSSENCGPPPPISNGDTTSFPQKVYLPWS
180 190 200 210 220 230
240 250 260 270 280
pF1KE1 VVEYDCNPNFIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPELEYG--YVQPSVPPY--
:::.:. . ..: : . : .:.:. : :. ..: : . ::...: : . . ::
NP_001 RVEYQCQSYYELQGSKYVTCSNGDWSEPPRCI-SMKPCEF-PEIQHGHLYYENTRRPYFP
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 -QHGVSVEVNCRNEYAMIGN---NMITCINGIWTELPMCVATHQLKRCKIAGVNIKT-LL
: : : .... .. ..: : . : : :. :. . ..:.. ..
NP_001 VATGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWLPTVPC-----LRTCSKSDIEIENGFI
300 310 320 330 340
350 360 370 380 390
pF1KE1 KLSGKEFNHNSRIRYRCSDIFRYRHS------VCINGKWNPEVDCTEKREQFCPPPPQIP
. :.. . :..:.:.:. . . .:... :. . : .:: : .
NP_001 SESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICI----KFCDMPV-FE
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE1 NAQNMTTTVNYQDGEKVAVLCKENYLLPEAKE---IVCKDGRWQSLPRCVESTAYCGPPP
:.. .. . .. . . : ..: . .. ::: . :. .: : .:. :::::
NP_001 NSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPP
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE1 SINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEEN
:.::::::: :.:: : : : :.:::.:.:::: ::: : .:::::::. ::...:::
NP_001 PISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEEN
470 480 490 500 510 520
520 530 540 550 560
pF1KE1 MNKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSPPFRAICQEGKFEYPICE
::::::::: ..: : ::::::..::.::. ..: : :.:.:.:: ::: ::
NP_001 MNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRCE
530 540 550 560 570
>>XP_006711192 (OMIM: 605337) PREDICTED: complement fact (570 aa)
initn: 1084 init1: 629 opt: 1316 Z-score: 1401.5 bits: 269.2 E(85289): 2.5e-71
Smith-Waterman score: 1316; 35.8% identity (61.7% similar) in 595 aa overlap (1-569:1-570)
10 20 30 40 50 60
pF1KE1 MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFV
::::..::: ::: ..:. .:.:: :: . . . .:. . : :. :::
XP_006 MLLLINVILTLWVSCANGQ-------EIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFV
10 20 30 40 50
70 80 90 100 110
pF1KE1 SPSKSFWTRITCTEEGWSPTPKCLRMCSFP--FVKNGHSESSGLIHLEGDTVQIICNTGY
.:: :.: : ::..::::: ::: :: ..:: :. :.. .. .: :. ::
XP_006 TPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDVEIENGFISESSSIYILNEETQYNCKPGY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 SLQ--NNEKNISCVERGWSTPPIC-SFTKGECHVPILEANVDAQPKKESYKVGDVLKFSC
. :. .:.:.. :::: ::: .: : .:..: : :. . .:. :.: . :
XP_006 ATAEGNSSGSITCLQNGWSTQPICIKF----CDMPVFE-NSRAKSNGMWFKLHDTLDYEC
120 130 140 150 160
180 190 200 210 220 230
pF1KE1 RKNL-IRVG--SDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEV
. : .::. : . ::: ..::: .. ..::::: .:::.. . .. :
XP_006 YDGYESSYGNTTDSIVCGEDGWS-HLPTCYNSSENCGPPPPISNGDTTSFPQKVYLPWSR
170 180 190 200 210 220
240 250 260 270 280
pF1KE1 VEYDCNPNFIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPELEYG--YVQPSVPPY---
:::.:. . ..: : . : .:.:. : :. ..: : . ::...: : . . ::
XP_006 VEYQCQSYYELQGSKYVTCSNGDWSEPPRCI-SMKPCEF-PEIQHGHLYYENTRRPYFPV
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 QHGVSVEVNCRNEYAMIGN---NMITCINGIWTELPMCVATHQLKRCKIAGVNIKT-LLK
: : : .... .. ..: : . : : :. :. . ..:.. ...
XP_006 ATGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWLPTVPC-----LRTCSKSDIEIENGFIS
290 300 310 320 330 340
350 360 370 380 390
pF1KE1 LSGKEFNHNSRIRYRCSDIFRYRHS------VCINGKWNPEVDCTEKREQFCPPPPQIPN
:.. . :..:.:.:. . . .:... :. . : .:: : . :
XP_006 ESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICI----KFCDMPV-FEN
350 360 370 380 390
400 410 420 430 440 450
pF1KE1 AQNMTTTVNYQDGEKVAVLCKENYLLPEAKE---IVCKDGRWQSLPRCVESTAYCGPPPS
.. .. . .. . . : ..: . .. ::: . :. .: : .:. :::::
XP_006 SRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPP
400 410 420 430 440 450
460 470 480 490 500 510
pF1KE1 INNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENM
:.::::::: :.:: : : : :.:::.:.:::: ::: : .:::::::. ::...::::
XP_006 ISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENM
460 470 480 490 500 510
520 530 540 550 560
pF1KE1 NKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSPPFRAICQEGKFEYPICE
:::::::: ..: : ::::::..::.::. ..: : :.:.:.:: ::: ::
XP_006 NKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRCE
520 530 540 550 560 570
>>NP_002104 (OMIM: 134371,235400,603075) complement fact (330 aa)
initn: 1639 init1: 1031 opt: 1133 Z-score: 1209.9 bits: 233.0 E(85289): 1.2e-60
Smith-Waterman score: 1133; 51.7% identity (68.4% similar) in 329 aa overlap (1-322:1-327)
10 20 30 40 50 60
pF1KE1 MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFV
: :: :::::: .:.::::.:.::::::.::.::::: :.::::::::::::::::::::
NP_002 MWLLVSVILISRISSVGGEATFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSL
:::::::::::::::::::::::::.: ::::.:::::::: ::::::::::::::: :
NP_002 SPSKSFWTRITCTEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRL
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 QNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKES-YKVGDVLKFSCRKNL
::::.::::::::::::: : : : : :. .. : : :. ... ::.
NP_002 QNNENNISCVERGWSTPPKCRSTDTSCVNPPTVQNAHILSRQMSKYPSGERVRYECRSPY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 IRVGSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNP
:.. :.: . .:. : :: .. .::::: ..::.. . :. :::.:.
NP_002 EMFGDEEVMCLNGNWTEP-PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQN
190 200 210 220 230
240 250 260 270 280 290
pF1KE1 NFIINGPKKIQCVDGEWTTLPTCVEQVKTCGYIPE---LEYGYVQPSVPPYQHGVSVEVN
. ..: :.: : .:.:. : :.. : : . .. . . : :.:
NP_002 LYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYLRTGESAEFV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 CRNEYAMIGNNMI---TCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNS
:. : . . . :: .: : : :
NP_002 CKRGYRLSSRSHTLRTTCWDGK-LEYPTCAKR
300 310 320 330
>>XP_011507586 (OMIM: 134580,613235) PREDICTED: coagulat (675 aa)
initn: 937 init1: 496 opt: 939 Z-score: 999.5 bits: 195.1 E(85289): 6.2e-49
Smith-Waterman score: 939; 31.2% identity (59.5% similar) in 504 aa overlap (87-568:25-514)
60 70 80 90 100
pF1KE1 YNFVSPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNG------HSESSGLIHLEGDT-
:.:: :.:: .. .: . . :
XP_011 MRLKNLTFIIILIISGELYAEEKPCGFPHVENGRIAQYYYTFKSFYFPMSIDKK
10 20 30 40 50
110 120 130 140 150 160
pF1KE1 VQIICNTGYSLQNN--EKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKV
....: .::. ... :.. .:. .::: : : : : : : : .: . : ::.
XP_011 LSFFCLAGYTTESGRQEEQTTCTTEGWSPEPRC-FKK--CTKPDL-SNGYISDVKLLYKI
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE1 GDVLKFSCRKNLIRVGS---DSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRK
. ....: .. .:. . ::: . ::: . :::. . ..: : .: ::. . .:
XP_011 QENMRYGCASGYKTTGGKDEEVVQCLSDGWSSQ-PTCRKEHETCLAP-ELYNGNYSTTQK
120 130 140 150 160
230 240 250 260 270 280
pF1KE1 EEYGHNEVVEYDCNPNFIINGPKK---IQCVDGEWTTLPTCVEQVKTCGYIPELEYGYVQ
. .. :.:.: .. : :: ..:. :. : :. ..: :. . .: :: .
XP_011 T-FKVKDKVQYECATGYYTAGGKKTEEVECLTYGWSLTPKCT-KLK-CSSLRLIENGYFH
170 180 190 200 210 220
290 300 310 320 330 340
pF1KE1 PSVPPYQHGVSVEVNCRNEYAMIGNNMITCINGIW-TELPMCVATHQLKRCKIAGVNIKT
: :..: :. :...: . :...: : : : : :.: . .. :: . :..
XP_011 PVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFGWYPESPVCEGRRN--RCPPPPLPINS
230 240 250 260 270 280
350 360 370 380 390
pF1KE1 LLKLSGKEFNHNSRIRYRCSDIFRYRHSV---CINGKWNPEVDCTEKREQFCPPPPQIPN
.. . . :. .. .: :. . :. : .:::. : ... : :: : :
XP_011 KIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGKWTEPPKCIGQEKVACEEPPFIEN
290 300 310 320 330 340
400 410 420 430 440 450
pF1KE1 -AQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKDGRWQSLPRCVESTAYCGPPPSIN
: :. . . : .:.::. :: .::: ..::.:. :.: :.:::.. : :: .
XP_011 GAANLHSKI-YYNGDKVTYACKSGYLLHGSNEITCNRGKWTLPPECVENNENCKHPPVVM
350 360 370 380 390 400
460 470 480 490 500 510
pF1KE1 NGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENMNK
:: ... :. : ::.: :::. .: :.:: :.. .:: :: ::.::.:. . ::.
XP_011 NGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSPPVCLEPCTVNVDYMNR
410 420 430 440 450 460
520 530 540 550 560
pF1KE1 NNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSP--PFRAICQEGKFEYPICE
:::..::. .::. :: ..: :: . .: . . :..:. .::.:
XP_011 NNIEMKWKYEGKVLH--GDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTRKESK
470 480 490 500 510 520
XP_011 GMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCLDGMWTTPPLCLEP
530 540 550 560 570 580
>--
initn: 406 init1: 283 opt: 337 Z-score: 359.1 bits: 76.6 E(85289): 2.9e-13
Smith-Waterman score: 337; 36.7% identity (66.4% similar) in 128 aa overlap (444-568:518-645)
420 430 440 450 460 470
pF1KE1 AVLCKENYLLPEAKEIVCKDGRWQSLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGST
:: ..: :: :..: : ...: ::.
XP_011 GYDLSPLTPLSELSVQCNRGEVKYPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSS
490 500 510 520 530 540
480 490 500 510 520 530
pF1KE1 VTYRCQSFYKLQGSVTVTCRNKQWSEPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKT
: ::: . . :.:: . : . .:. :: ::.::..: .:.:::. ::: :.. .
XP_011 VEYRCFDHHFLEGSREAYCLDGMWTTPPLCLEPCTLSFTEMEKNNLLLKWDFDNRPHILH
550 560 570 580 590 600
540 550 560
pF1KE1 GDAVEFQCK---FPHKAMISSPPFRAICQEGKFEYPICE
:. .:: :. .: . .:.. .: :..:...:: :
XP_011 GEYIEFICRGDTYPAELYITGSILRMQCDRGQLKYPRCIPRQSKQTTGSGNQFNRPSELS
610 620 630 640 650 660
XP_011 EVKATFAI
670
>>NP_005657 (OMIM: 600889) complement factor H-related p (270 aa)
initn: 1476 init1: 857 opt: 929 Z-score: 994.0 bits: 192.7 E(85289): 1.3e-48
Smith-Waterman score: 929; 53.5% identity (72.5% similar) in 273 aa overlap (1-265:1-270)
10 20 30 40 50 60
pF1KE1 MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFV
: :: :::::: .:.::::. .::::::.::.::::: :.::::::::::::::::::::
NP_005 MWLLVSVILISRISSVGGEAMFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSL
::::::::::::.::::::::::::.: ::::.:::::::: ::::::::::::::: :
NP_005 SPSKSFWTRITCAEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRL
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 QNNEKNISCVERGWSTPPIC--SFTKGECHVPILEANVDAQPKKES-YKVGDVLKFSCRK
::::.::::::::::::: : ... .: : : : : : :. ....: .
NP_005 QNNENNISCVERGWSTPPKCRSTISAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQC-Q
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 NLIRV-GSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEE-YGHN-EVVE
:: .. :.... : . :: : : . : ..: ... :... ..::
NP_005 NLYQLEGNNQITCRNGQWSEP-PKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 YDCNPNFIINGPK--KIQCVDGEWTTLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVS
. :. .. . . . .: .:. . :.: :.
NP_005 FVCKSGYHPTKSHSFRAMCQNGK-LVYPSCEEK
240 250 260 270
300 310 320 330 340 350
pF1KE1 VEVNCRNEYAMIGNNMITCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHN
>>XP_011507760 (OMIM: 600889) PREDICTED: complement fact (266 aa)
initn: 1065 init1: 855 opt: 925 Z-score: 989.8 bits: 191.9 E(85289): 2.2e-48
Smith-Waterman score: 925; 53.9% identity (72.7% similar) in 271 aa overlap (1-265:1-266)
10 20 30 40 50 60
pF1KE1 MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFV
: :: :::::: .:.::::. .::::::.::.::::: :.::::::::::::::::::::
XP_011 MWLLVSVILISRISSVGGEAMFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSL
::::::::::::.::::::::::::.: ::::.:::::::: ::::::::::::::: :
XP_011 SPSKSFWTRITCAEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRL
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 QNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKES-YKVGDVLKFSCRKNL
::::.::::::::::::: .:. .: : : : : : :. ....: .::
XP_011 QNNENNISCVERGWSTPP--KFSAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQC-QNL
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 IRV-GSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEE-YGHN-EVVEYD
.. :.... : . :: : : . : ..: ... :... ..::.
XP_011 YQLEGNNQITCRNGQWSEP-PKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 CNPNFIINGPK--KIQCVDGEWTTLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVE
:. .. . . . .: .:. . :.: :.
XP_011 CKSGYHPTKSHSFRAMCQNGK-LVYPSCEEK
240 250 260
300 310 320 330 340 350
pF1KE1 VNCRNEYAMIGNNMITCINGIWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSR
569 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:44:54 2016 done: Sun Nov 6 18:44:56 2016
Total Scan time: 9.810 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]