Result of FASTA (omim) for
pFN21AE1969
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1969, 534 aa
1>>>pF1KE1969 534 - 534 aa - 534 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3102+/-0.000378; mu= 18.4784+/- 0.023
mean_var=72.8657+/-15.222, 0's: 0 Z-trim(113.2): 181 B-trim: 1246 in 1/52
Lambda= 0.150249
statistics sampled from 22296 (22483) to 22296 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.264), width: 16
Scan time: 9.810
The best scores are: opt bits E(85289)
NP_001124438 (OMIM: 231095,274180,614158) thrombox ( 534) 3607 791.5 0
NP_001052 (OMIM: 231095,274180,614158) thromboxane ( 534) 3607 791.5 0
NP_001159726 (OMIM: 231095,274180,614158) thrombox ( 466) 3158 694.1 2.3e-199
NP_001300957 (OMIM: 231095,274180,614158) thrombox ( 514) 3101 681.8 1.3e-195
NP_112246 (OMIM: 231095,274180,614158) thromboxane ( 460) 3088 679.0 8.5e-195
XP_011514846 (OMIM: 231095,274180,614158) PREDICTE ( 463) 3084 678.1 1.6e-194
XP_016868058 (OMIM: 231095,274180,614158) PREDICTE ( 472) 2864 630.4 3.6e-180
NP_001159725 (OMIM: 231095,274180,614158) thrombox ( 580) 2612 575.9 1.2e-163
XP_016868061 (OMIM: 231095,274180,614158) PREDICTE ( 411) 2543 560.8 2.9e-159
XP_016868060 (OMIM: 231095,274180,614158) PREDICTE ( 418) 2543 560.8 2.9e-159
XP_016868059 (OMIM: 231095,274180,614158) PREDICTE ( 451) 2543 560.8 3.1e-159
XP_016867271 (OMIM: 145500,605325) PREDICTED: cyto ( 322) 633 146.7 1e-34
NP_001189784 (OMIM: 124010) cytochrome P450 3A4 is ( 502) 627 145.5 3.5e-34
NP_059488 (OMIM: 124010) cytochrome P450 3A4 isofo ( 503) 627 145.5 3.5e-34
NP_000756 (OMIM: 605340) cytochrome P450 3A7 [Homo ( 503) 612 142.3 3.4e-33
NP_001265850 (OMIM: 606534) cytochrome P450 3A43 i ( 393) 576 134.4 6.2e-31
XP_016868034 (OMIM: 606534) PREDICTED: cytochrome ( 360) 564 131.8 3.5e-30
XP_016868033 (OMIM: 606534) PREDICTED: cytochrome ( 360) 564 131.8 3.5e-30
XP_016867269 (OMIM: 124010) PREDICTED: cytochrome ( 449) 551 129.0 2.9e-29
NP_476437 (OMIM: 606534) cytochrome P450 3A43 isof ( 420) 531 124.7 5.6e-28
NP_476436 (OMIM: 606534) cytochrome P450 3A43 isof ( 503) 531 124.7 6.5e-28
NP_073731 (OMIM: 606534) cytochrome P450 3A43 isof ( 504) 531 124.7 6.5e-28
XP_006715922 (OMIM: 145500,605325) PREDICTED: cyto ( 381) 529 124.2 7e-28
NP_000768 (OMIM: 145500,605325) cytochrome P450 3A ( 502) 529 124.3 8.8e-28
NP_001278759 (OMIM: 145500,605325) cytochrome P450 ( 492) 528 124.1 1e-27
XP_016863526 (OMIM: 210370,608614) PREDICTED: cyto ( 393) 466 110.6 9.3e-24
NP_997235 (OMIM: 210370,608614) cytochrome P450 4V ( 525) 466 110.7 1.2e-23
XP_005262992 (OMIM: 210370,608614) PREDICTED: cyto ( 524) 456 108.5 5.3e-23
NP_009184 (OMIM: 611545) cytochrome P450 4F8 precu ( 520) 426 102.0 4.7e-21
XP_011526509 (OMIM: 611485) PREDICTED: cytochrome ( 334) 410 98.4 3.7e-20
XP_011526506 (OMIM: 611485) PREDICTED: cytochrome ( 352) 410 98.4 3.8e-20
XP_011526507 (OMIM: 611485) PREDICTED: cytochrome ( 352) 410 98.4 3.8e-20
XP_011526505 (OMIM: 611485) PREDICTED: cytochrome ( 352) 410 98.4 3.8e-20
XP_011526510 (OMIM: 611485) PREDICTED: cytochrome ( 375) 410 98.4 4e-20
XP_006722913 (OMIM: 611485) PREDICTED: cytochrome ( 375) 410 98.4 4e-20
XP_011526504 (OMIM: 611485) PREDICTED: cytochrome ( 375) 410 98.4 4e-20
NP_076433 (OMIM: 611485) cytochrome P450 4F12 [Hom ( 524) 410 98.5 5.3e-20
NP_001307219 (OMIM: 614999) cytochrome P450 4X1 is ( 444) 408 98.0 6.3e-20
NP_001307218 (OMIM: 614999) cytochrome P450 4X1 is ( 508) 408 98.1 7e-20
NP_828847 (OMIM: 614999) cytochrome P450 4X1 isofo ( 509) 408 98.1 7e-20
NP_001073 (OMIM: 604426) phylloquinone omega-hydro ( 520) 404 97.2 1.3e-19
XP_005259968 (OMIM: 601270) PREDICTED: docosahexae ( 371) 397 95.6 2.8e-19
XP_011526316 (OMIM: 601270) PREDICTED: docosahexae ( 371) 397 95.6 2.8e-19
NP_000887 (OMIM: 601270) docosahexaenoic acid omeg ( 520) 397 95.7 3.7e-19
NP_001186138 (OMIM: 601270) docosahexaenoic acid o ( 520) 397 95.7 3.7e-19
XP_016882303 (OMIM: 601270) PREDICTED: docosahexae ( 520) 397 95.7 3.7e-19
NP_001186137 (OMIM: 601270) docosahexaenoic acid o ( 520) 397 95.7 3.7e-19
NP_001122404 (OMIM: 611517) phylloquinone omega-hy ( 524) 396 95.5 4.3e-19
NP_067010 (OMIM: 611517) phylloquinone omega-hydro ( 524) 396 95.5 4.3e-19
NP_775754 (OMIM: 611495) cytochrome P450 4F22 [Hom ( 531) 390 94.2 1.1e-18
>>NP_001124438 (OMIM: 231095,274180,614158) thromboxane- (534 aa)
initn: 3607 init1: 3607 opt: 3607 Z-score: 4225.2 bits: 791.5 E(85289): 0
Smith-Waterman score: 3607; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE1 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSC
430 440 450 460 470 480
490 500 510 520 530
pF1KE1 LGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
490 500 510 520 530
>>NP_001052 (OMIM: 231095,274180,614158) thromboxane-A s (534 aa)
initn: 3607 init1: 3607 opt: 3607 Z-score: 4225.2 bits: 791.5 E(85289): 0
Smith-Waterman score: 3607; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE1 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSC
430 440 450 460 470 480
490 500 510 520 530
pF1KE1 LGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
490 500 510 520 530
>>NP_001159726 (OMIM: 231095,274180,614158) thromboxane- (466 aa)
initn: 3158 init1: 3158 opt: 3158 Z-score: 3700.1 bits: 694.1 E(85289): 2.3e-199
Smith-Waterman score: 3158; 100.0% identity (100.0% similar) in 466 aa overlap (69-534:1-466)
40 50 60 70 80 90
pF1KE1 RLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIK
::::::::::::::::::::::::::::::
NP_001 MELRKLYGPLCGYYLGRRMFIVISEPDMIK
10 20 30
100 110 120 130 140 150
pF1KE1 QVLVENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVLVENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQ
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE1 ACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFF
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE1 EFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRD
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE1 FLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFI
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE1 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVI
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE1 AETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFT
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE1 AEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESK
400 410 420 430 440 450
520 530
pF1KE1 SALGPKNGVYIKIVSR
::::::::::::::::
NP_001 SALGPKNGVYIKIVSR
460
>>NP_001300957 (OMIM: 231095,274180,614158) thromboxane- (514 aa)
initn: 3070 init1: 3070 opt: 3101 Z-score: 3632.7 bits: 681.8 E(85289): 1.3e-195
Smith-Waterman score: 3101; 91.1% identity (94.2% similar) in 514 aa overlap (21-534:5-514)
10 20 30 40 50 60
pF1KE1 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
.:. . .. ...::: :: . : :.:. .
NP_001 MVLHISILKTGEVRPQTSQAFSFHWKLDIF---PPGFLGKPNGA
10 20 30 40
70 80 90 100 110 120
pF1KE1 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
... : : ::: . ::::::::::::::::::::::::::::::::::::::::
NP_001 QKAVWTSVWVRRKLNVSIM-YYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE1 NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE1 VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSC
410 420 430 440 450 460
490 500 510 520 530
pF1KE1 LGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
470 480 490 500 510
>>NP_112246 (OMIM: 231095,274180,614158) thromboxane-A s (460 aa)
initn: 3114 init1: 3088 opt: 3088 Z-score: 3618.2 bits: 679.0 E(85289): 8.5e-195
Smith-Waterman score: 3088; 99.8% identity (100.0% similar) in 457 aa overlap (1-457:1-457)
10 20 30 40 50 60
pF1KE1 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSC
::::::::::::::::::::::::::::::::::::.
NP_112 VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERYRCS
430 440 450 460
490 500 510 520 530
pF1KE1 LGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
>>XP_011514846 (OMIM: 231095,274180,614158) PREDICTED: t (463 aa)
initn: 3084 init1: 3084 opt: 3084 Z-score: 3613.4 bits: 678.1 E(85289): 1.6e-194
Smith-Waterman score: 3084; 100.0% identity (100.0% similar) in 456 aa overlap (1-456:1-456)
10 20 30 40 50 60
pF1KE1 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSC
::::::::::::::::::::::::::::::::::::
XP_011 VLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERSKLNPEI
430 440 450 460
490 500 510 520 530
pF1KE1 LGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
>>XP_016868058 (OMIM: 231095,274180,614158) PREDICTED: t (472 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 3355.6 bits: 630.4 E(85289): 3.6e-180
Smith-Waterman score: 2864; 99.1% identity (99.5% similar) in 427 aa overlap (108-534:46-472)
80 90 100 110 120 130
pF1KE1 LCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVR
.:. :::::::::::::::::::::::::
XP_016 QTSQAFSFHWKLDIFPPGFLGKPNGAQKAVWTSVWASGLEFKSVADSVLFLRDKRWEEVR
20 30 40 50 60 70
140 150 160 170 180 190
pF1KE1 GALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFG
80 90 100 110 120 130
200 210 220 230 240 250
pF1KE1 TPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFN
140 150 160 170 180 190
260 270 280 290 300 310
pF1KE1 KLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQ
200 210 220 230 240 250
320 330 340 350 360 370
pF1KE1 HQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKE
260 270 280 290 300 310
380 390 400 410 420 430
pF1KE1 KHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVG
320 330 340 350 360 370
440 450 460 470 480 490
pF1KE1 ALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHV
380 390 400 410 420 430
500 510 520 530
pF1KE1 LHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
:::::::::::::::::::::::::::::::::::::
XP_016 LHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
440 450 460 470
>>NP_001159725 (OMIM: 231095,274180,614158) thromboxane- (580 aa)
initn: 2612 init1: 2612 opt: 2612 Z-score: 3059.1 bits: 575.9 E(85289): 1.2e-163
Smith-Waterman score: 3417; 91.9% identity (91.9% similar) in 566 aa overlap (15-534:15-580)
10 20 30 40 50 60
pF1KE1 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
70 80 90 100 110 120
130 140 150
pF1KE1 VADSVLFLRDKRWEEVRGALMSAFSPEKLNE-----------------------------
:::::::::::::::::::::::::::::::
NP_001 VADSVLFLRDKRWEEVRGALMSAFSPEKLNELGLLIMQERIKGHMGGQQAPQRIPPTRLS
130 140 150 160 170 180
160 170 180 190
pF1KE1 -----------------MVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASV
:::::::::::::::::::::::::::::::::::::::::::
NP_001 KPSGIYVNLHYATLPFCMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASV
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE1 AFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNG
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE1 FFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNP
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE1 SRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDV
370 380 390 400 410 420
380 390 400 410 420 430
pF1KE1 FKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEM
430 440 450 460 470 480
440 450 460 470 480 490
pF1KE1 AVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTL
490 500 510 520 530 540
500 510 520 530
pF1KE1 LHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
::::::::::::::::::::::::::::::::::::::::
NP_001 LHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
550 560 570 580
>>XP_016868061 (OMIM: 231095,274180,614158) PREDICTED: t (411 aa)
initn: 2567 init1: 2541 opt: 2543 Z-score: 2980.4 bits: 560.8 E(85289): 2.9e-159
Smith-Waterman score: 2543; 99.0% identity (99.5% similar) in 385 aa overlap (1-383:1-385)
10 20 30 40 50 60
pF1KE1 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 NPDCQEKLLREVDVFKEKHM--APEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQD
:::::::::::::::::::. .::
XP_016 NPDCQEKLLREVDVFKEKHVQRGPESSLLLLHLLTHCPLGAPGHPRSLYHL
370 380 390 400 410
>>XP_016868060 (OMIM: 231095,274180,614158) PREDICTED: t (418 aa)
initn: 2567 init1: 2541 opt: 2543 Z-score: 2980.3 bits: 560.8 E(85289): 2.9e-159
Smith-Waterman score: 2543; 99.0% identity (99.5% similar) in 385 aa overlap (1-383:1-385)
10 20 30 40 50 60
pF1KE1 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLAT
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 NPDCQEKLLREVDVFKEKHM--APEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQD
:::::::::::::::::::. .::
XP_016 NPDCQEKLLREVDVFKEKHVQRGPESSLLLLHLLTHCPLGAPGHPRSLEMHLRHWHAA
370 380 390 400 410
534 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 16:15:02 2016 done: Sun Nov 6 16:15:04 2016
Total Scan time: 9.810 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]