Result of FASTA (omim) for
pFN21AE1956
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1956, 513 aa
1>>>pF1KE1956 513 - 513 aa - 513 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1077+/-0.00043; mu= 16.0777+/- 0.026
mean_var=135.5214+/-28.041, 0's: 0 Z-trim(115.2): 19 B-trim: 1053 in 1/49
Lambda= 0.110172
statistics sampled from 25462 (25478) to 25462 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.299), width: 16
Scan time: 8.700
The best scores are: opt bits E(85289)
NP_079212 (OMIM: 611792) zinc finger CCHC domain-c ( 513) 3621 587.5 3.1e-167
XP_016863617 (OMIM: 611792) PREDICTED: zinc finger ( 468) 3039 495.0 2.1e-139
XP_011512137 (OMIM: 611792) PREDICTED: zinc finger ( 528) 2430 398.2 3.1e-110
NP_001305077 (OMIM: 611792) zinc finger CCHC domai ( 339) 2341 383.9 4.1e-106
XP_016863618 (OMIM: 611792) PREDICTED: zinc finger ( 429) 1750 290.0 9.2e-78
>>NP_079212 (OMIM: 611792) zinc finger CCHC domain-conta (513 aa)
initn: 3621 init1: 3621 opt: 3621 Z-score: 3123.3 bits: 587.5 E(85289): 3.1e-167
Smith-Waterman score: 3621; 99.6% identity (99.8% similar) in 513 aa overlap (1-513:1-513)
10 20 30 40 50 60
pF1KE1 MAASRNGFEAVEAEGSAGCRGSSGMEVVLPLDPAVPAPLCPHGPTLLFVKVTQGKEETRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MAASRNGFEAVEAEGSAGCRGSSGMEVVLPLDPAVPAPLCPHGPTLLFVKVTQGKEETRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FYACSACRDRKDCNFFQWEDEKLSGARLAAREAHNRRCQPPLSRTQCVERYLKFIELPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 FYACSACRDRKDCNFFQWEDEKLSGARLAAREAHNRRCQPPLSRTQCVERYLKFIELPLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQYLFADRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQYLFADRSC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIKSLLLDIDFRYSQFYMEDSFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIKSLLLDIDFRYSQFYMEDSFC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RYNMFNHHFFDGKTALEVCRAFLQEDKGEGIIMVTDPPFGGLVEPLAITFKKLIAMWKEG
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 HYNMFNHHFFDGKTALEVCRAFLQEDKGEGIIMVTDPPFGGLVEPLAITFKKLIAMWKEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QSQDDSHKELPIFWIFPYFFESRICQFFPSFQMLDYQVDYDNHALYKHGKTGRKQSPVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QSQDDSHKELPIFWIFPYFFESRICQFFPSFQMLDYQVDYDNHALYKHGKTGRKQSPVRI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FTNIPPNKIILPTEEGYRFCSPCQRYVSLENQHCEHCNSCTSKDGRKWNHCFLCKKCVKP
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_079 FTNIPPNKIILPTEEGYRFCSPCQRYVSLENQHCELCNSCTSKDGRKWNHCFLCKKCVKP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SWIHCSICNHCAVPDHSCEGPKHGCFICGELDHKRSTCPNIATSKRANKAVRKQKQRKSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SWIHCSICNHCAVPDHSCEGPKHGCFICGELDHKRSTCPNIATSKRANKAVRKQKQRKSN
430 440 450 460 470 480
490 500 510
pF1KE1 KMKMETTKGQSMNHTSATRRKKRRERAHQYLGS
:::::::::::::::::::::::::::::::::
NP_079 KMKMETTKGQSMNHTSATRRKKRRERAHQYLGS
490 500 510
>>XP_016863617 (OMIM: 611792) PREDICTED: zinc finger CCH (468 aa)
initn: 3039 init1: 3039 opt: 3039 Z-score: 2623.9 bits: 495.0 E(85289): 2.1e-139
Smith-Waterman score: 3039; 99.5% identity (99.8% similar) in 431 aa overlap (83-513:38-468)
60 70 80 90 100 110
pF1KE1 QGKEETRRFYACSACRDRKDCNFFQWEDEKLSGARLAAREAHNRRCQPPLSRTQCVERYL
::::::::::::::::::::::::::::::
XP_016 QRAAQGAGEAREWRWCFLWILPSPPRCALTLSGARLAAREAHNRRCQPPLSRTQCVERYL
10 20 30 40 50 60
120 130 140 150 160 170
pF1KE1 KFIELPLTQRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFIELPLTQRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQ
70 80 90 100 110 120
180 190 200 210 220 230
pF1KE1 YLFADRSCQFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIKSLLLDIDFRYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLFADRSCQFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIKSLLLDIDFRYSQ
130 140 150 160 170 180
240 250 260 270 280 290
pF1KE1 FYMEDSFCRYNMFNHHFFDGKTALEVCRAFLQEDKGEGIIMVTDPPFGGLVEPLAITFKK
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYMEDSFCHYNMFNHHFFDGKTALEVCRAFLQEDKGEGIIMVTDPPFGGLVEPLAITFKK
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE1 LIAMWKEGQSQDDSHKELPIFWIFPYFFESRICQFFPSFQMLDYQVDYDNHALYKHGKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAMWKEGQSQDDSHKELPIFWIFPYFFESRICQFFPSFQMLDYQVDYDNHALYKHGKTG
250 260 270 280 290 300
360 370 380 390 400 410
pF1KE1 RKQSPVRIFTNIPPNKIILPTEEGYRFCSPCQRYVSLENQHCEHCNSCTSKDGRKWNHCF
::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_016 RKQSPVRIFTNIPPNKIILPTEEGYRFCSPCQRYVSLENQHCELCNSCTSKDGRKWNHCF
310 320 330 340 350 360
420 430 440 450 460 470
pF1KE1 LCKKCVKPSWIHCSICNHCAVPDHSCEGPKHGCFICGELDHKRSTCPNIATSKRANKAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCKKCVKPSWIHCSICNHCAVPDHSCEGPKHGCFICGELDHKRSTCPNIATSKRANKAVR
370 380 390 400 410 420
480 490 500 510
pF1KE1 KQKQRKSNKMKMETTKGQSMNHTSATRRKKRRERAHQYLGS
:::::::::::::::::::::::::::::::::::::::::
XP_016 KQKQRKSNKMKMETTKGQSMNHTSATRRKKRRERAHQYLGS
430 440 450 460
>>XP_011512137 (OMIM: 611792) PREDICTED: zinc finger CCH (528 aa)
initn: 2410 init1: 2341 opt: 2430 Z-score: 2100.1 bits: 398.2 E(85289): 3.1e-110
Smith-Waterman score: 3581; 96.8% identity (97.0% similar) in 528 aa overlap (1-513:1-528)
10 20 30 40 50 60
pF1KE1 MAASRNGFEAVEAEGSAGCRGSSGMEVVLPLDPAVPAPLCPHGPTLLFVKVTQGKEETRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAASRNGFEAVEAEGSAGCRGSSGMEVVLPLDPAVPAPLCPHGPTLLFVKVTQGKEETRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FYACSACRDRKDCNFFQWEDEKLSGARLAAREAHNRRCQPPLSRTQCVERYLKFIELPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYACSACRDRKDCNFFQWEDEKLSGARLAAREAHNRRCQPPLSRTQCVERYLKFIELPLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQYLFADRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQYLFADRSC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIKSLLLDIDFRYSQFYMEDSFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIKSLLLDIDFRYSQFYMEDSFC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RYNMFNHHFFDGKTALEVCRAFLQEDKGEGIIMVTDPPFGGLVEPLAITFKKLIAMWKEG
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HYNMFNHHFFDGKTALEVCRAFLQEDKGEGIIMVTDPPFGGLVEPLAITFKKLIAMWKEG
250 260 270 280 290 300
310 320 330 340
pF1KE1 QSQDDSHKELPIFWIFPYFFESRICQFFPSFQMLDYQ---------------VDYDNHAL
::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 QSQDDSHKELPIFWIFPYFFESRICQFFPSFQMLDYQAIPFFLDYRLFLPFKVDYDNHAL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE1 YKHGKTGRKQSPVRIFTNIPPNKIILPTEEGYRFCSPCQRYVSLENQHCEHCNSCTSKDG
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_011 YKHGKTGRKQSPVRIFTNIPPNKIILPTEEGYRFCSPCQRYVSLENQHCELCNSCTSKDG
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE1 RKWNHCFLCKKCVKPSWIHCSICNHCAVPDHSCEGPKHGCFICGELDHKRSTCPNIATSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKWNHCFLCKKCVKPSWIHCSICNHCAVPDHSCEGPKHGCFICGELDHKRSTCPNIATSK
430 440 450 460 470 480
470 480 490 500 510
pF1KE1 RANKAVRKQKQRKSNKMKMETTKGQSMNHTSATRRKKRRERAHQYLGS
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RANKAVRKQKQRKSNKMKMETTKGQSMNHTSATRRKKRRERAHQYLGS
490 500 510 520
>>NP_001305077 (OMIM: 611792) zinc finger CCHC domain-co (339 aa)
initn: 2341 init1: 2341 opt: 2341 Z-score: 2026.0 bits: 383.9 E(85289): 4.1e-106
Smith-Waterman score: 2341; 99.7% identity (100.0% similar) in 337 aa overlap (1-337:1-337)
10 20 30 40 50 60
pF1KE1 MAASRNGFEAVEAEGSAGCRGSSGMEVVLPLDPAVPAPLCPHGPTLLFVKVTQGKEETRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASRNGFEAVEAEGSAGCRGSSGMEVVLPLDPAVPAPLCPHGPTLLFVKVTQGKEETRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FYACSACRDRKDCNFFQWEDEKLSGARLAAREAHNRRCQPPLSRTQCVERYLKFIELPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYACSACRDRKDCNFFQWEDEKLSGARLAAREAHNRRCQPPLSRTQCVERYLKFIELPLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQYLFADRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQYLFADRSC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIKSLLLDIDFRYSQFYMEDSFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIKSLLLDIDFRYSQFYMEDSFC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RYNMFNHHFFDGKTALEVCRAFLQEDKGEGIIMVTDPPFGGLVEPLAITFKKLIAMWKEG
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYNMFNHHFFDGKTALEVCRAFLQEDKGEGIIMVTDPPFGGLVEPLAITFKKLIAMWKEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QSQDDSHKELPIFWIFPYFFESRICQFFPSFQMLDYQVDYDNHALYKHGKTGRKQSPVRI
:::::::::::::::::::::::::::::::::::::
NP_001 QSQDDSHKELPIFWIFPYFFESRICQFFPSFQMLDYQGI
310 320 330
370 380 390 400 410 420
pF1KE1 FTNIPPNKIILPTEEGYRFCSPCQRYVSLENQHCEHCNSCTSKDGRKWNHCFLCKKCVKP
>>XP_016863618 (OMIM: 611792) PREDICTED: zinc finger CCH (429 aa)
initn: 1819 init1: 1750 opt: 1750 Z-score: 1517.1 bits: 290.0 E(85289): 9.2e-78
Smith-Waterman score: 2852; 83.2% identity (83.4% similar) in 513 aa overlap (1-513:1-429)
10 20 30 40 50 60
pF1KE1 MAASRNGFEAVEAEGSAGCRGSSGMEVVLPLDPAVPAPLCPHGPTLLFVKVTQGKEETRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAASRNGFEAVEAEGSAGCRGSSGMEVVLPLDPAVPAPLCPHGPTLLFVKVTQGKEETRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FYACSACRDRKDCNFFQWEDEKLSGARLAAREAHNRRCQPPLSRTQCVERYLKFIELPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYACSACRDRKDCNFFQWEDEKLSGARLAAREAHNRRCQPPLSRTQCVERYLKFIELPLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQYLFADRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQYLFADRSC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 QFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIKSLLLDIDFRYSQFYMEDSFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIKSLLLDIDFRYSQFYMEDSFC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RYNMFNHHFFDGKTALEVCRAFLQEDKGEGIIMVTDPPFGGLVEPLAITFKKLIAMWKEG
.::::::::::::
XP_016 HYNMFNHHFFDGK-----------------------------------------------
250
310 320 330 340 350 360
pF1KE1 QSQDDSHKELPIFWIFPYFFESRICQFFPSFQMLDYQVDYDNHALYKHGKTGRKQSPVRI
:::::::::::::::::::::::
XP_016 -------------------------------------VDYDNHALYKHGKTGRKQSPVRI
260 270
370 380 390 400 410 420
pF1KE1 FTNIPPNKIILPTEEGYRFCSPCQRYVSLENQHCEHCNSCTSKDGRKWNHCFLCKKCVKP
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 FTNIPPNKIILPTEEGYRFCSPCQRYVSLENQHCELCNSCTSKDGRKWNHCFLCKKCVKP
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE1 SWIHCSICNHCAVPDHSCEGPKHGCFICGELDHKRSTCPNIATSKRANKAVRKQKQRKSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SWIHCSICNHCAVPDHSCEGPKHGCFICGELDHKRSTCPNIATSKRANKAVRKQKQRKSN
340 350 360 370 380 390
490 500 510
pF1KE1 KMKMETTKGQSMNHTSATRRKKRRERAHQYLGS
:::::::::::::::::::::::::::::::::
XP_016 KMKMETTKGQSMNHTSATRRKKRRERAHQYLGS
400 410 420
513 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:43:05 2016 done: Sun Nov 6 05:43:07 2016
Total Scan time: 8.700 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]