Result of FASTA (omim) for
pFN21AE1924
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1924, 461 aa
1>>>pF1KE1924 461 - 461 aa - 461 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6287+/-0.000342; mu= -1.5174+/- 0.021
mean_var=216.9666+/-43.085, 0's: 0 Z-trim(122.5): 89 B-trim: 0 in 0/55
Lambda= 0.087072
statistics sampled from 40642 (40731) to 40642 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.478), width: 16
Scan time: 11.660
The best scores are: opt bits E(85289)
NP_001057 (OMIM: 191191) tumor necrosis factor rec ( 461) 3198 414.1 4e-115
XP_011540365 (OMIM: 191191) PREDICTED: tumor necro ( 462) 3186 412.6 1.1e-114
XP_011540362 (OMIM: 191191) PREDICTED: tumor necro ( 484) 2570 335.2 2.3e-91
XP_016857700 (OMIM: 191191) PREDICTED: tumor necro ( 491) 2133 280.3 7.9e-75
XP_016857702 (OMIM: 191191) PREDICTED: tumor necro ( 440) 1784 236.5 1.1e-61
XP_016857701 (OMIM: 191191) PREDICTED: tumor necro ( 440) 1784 236.5 1.1e-61
XP_016857704 (OMIM: 191191) PREDICTED: tumor necro ( 266) 1763 233.7 4.6e-61
XP_016857703 (OMIM: 191191) PREDICTED: tumor necro ( 289) 1135 154.8 2.8e-37
XP_005253745 (OMIM: 600979) PREDICTED: tumor necro ( 399) 487 73.5 1.2e-12
NP_003814 (OMIM: 603361) tumor necrosis factor rec ( 300) 472 71.6 3.4e-12
XP_006719046 (OMIM: 600979) PREDICTED: tumor necro ( 255) 451 68.9 1.8e-11
NP_002537 (OMIM: 239000,602643) tumor necrosis fac ( 401) 455 69.5 1.9e-11
NP_002333 (OMIM: 600979) tumor necrosis factor rec ( 435) 451 69.0 2.9e-11
XP_016883624 (OMIM: 109535,606843) PREDICTED: tumo ( 323) 446 68.3 3.5e-11
NP_001289682 (OMIM: 109535,606843) tumor necrosis ( 237) 443 67.9 3.5e-11
NP_001257916 (OMIM: 600979) tumor necrosis factor ( 416) 437 67.2 9.4e-11
XP_016883626 (OMIM: 109535,606843) PREDICTED: tumo ( 222) 429 66.1 1.1e-10
NP_001241 (OMIM: 109535,606843) tumor necrosis fac ( 277) 429 66.1 1.3e-10
NP_001309350 (OMIM: 109535,606843) tumor necrosis ( 281) 429 66.1 1.4e-10
XP_016883625 (OMIM: 109535,606843) PREDICTED: tumo ( 289) 422 65.3 2.6e-10
XP_016866233 (OMIM: 605732) PREDICTED: tumor necro ( 444) 414 64.4 7.3e-10
NP_055267 (OMIM: 605732) tumor necrosis factor rec ( 655) 414 64.5 1e-09
NP_690593 (OMIM: 109535,606843) tumor necrosis fac ( 203) 401 62.5 1.2e-09
NP_001257878 (OMIM: 174810,602080,603499,612301) t ( 263) 397 62.1 2.1e-09
NP_001257879 (OMIM: 174810,602080,603499,612301) t ( 337) 397 62.2 2.6e-09
NP_001257880 (OMIM: 174810,602080,603499,612301) t ( 299) 394 61.8 3e-09
NP_003830 (OMIM: 174810,602080,603499,612301) tumo ( 616) 397 62.3 4.2e-09
XP_011524546 (OMIM: 174810,602080,603499,612301) P ( 621) 384 60.7 1.3e-08
XP_006711082 (OMIM: 602746) PREDICTED: tumor necro ( 197) 363 57.8 3.2e-08
NP_003811 (OMIM: 602746) tumor necrosis factor rec ( 283) 366 58.2 3.3e-08
NP_001284534 (OMIM: 602746) tumor necrosis factor ( 184) 361 57.5 3.5e-08
XP_011540743 (OMIM: 153243) PREDICTED: tumor necro ( 594) 359 57.5 1.1e-07
NP_001234 (OMIM: 153243) tumor necrosis factor rec ( 595) 359 57.5 1.1e-07
XP_011527411 (OMIM: 109535,606843) PREDICTED: tumo ( 166) 304 50.3 4.7e-06
NP_001309351 (OMIM: 109535,606843) tumor necrosis ( 225) 304 50.4 6e-06
XP_005260676 (OMIM: 109535,606843) PREDICTED: tumo ( 229) 304 50.4 6.1e-06
XP_016881554 (OMIM: 174810,602080,603499,612301) P ( 566) 311 51.5 7.1e-06
NP_001265197 (OMIM: 174810,602080,603499,612301) t ( 602) 237 42.2 0.0047
>>NP_001057 (OMIM: 191191) tumor necrosis factor recepto (461 aa)
initn: 3198 init1: 3198 opt: 3198 Z-score: 2187.8 bits: 414.1 E(85289): 4e-115
Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)
10 20 30 40 50 60
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQ
370 380 390 400 410 420
430 440 450 460
pF1KE1 VPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
:::::::::::::::::::::::::::::::::::::::::
NP_001 VPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
430 440 450 460
>>XP_011540365 (OMIM: 191191) PREDICTED: tumor necrosis (462 aa)
initn: 2610 init1: 2577 opt: 3186 Z-score: 2179.6 bits: 412.6 E(85289): 1.1e-114
Smith-Waterman score: 3186; 99.8% identity (99.8% similar) in 462 aa overlap (1-461:1-462)
10 20 30 40 50 60
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 ARASTGSS-DSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDE
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARASTGSSADSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDE
370 380 390 400 410 420
420 430 440 450 460
pF1KE1 QVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
::::::::::::::::::::::::::::::::::::::::::
XP_011 QVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
430 440 450 460
>>XP_011540362 (OMIM: 191191) PREDICTED: tumor necrosis (484 aa)
initn: 2749 init1: 2570 opt: 2570 Z-score: 1761.1 bits: 335.2 E(85289): 2.3e-91
Smith-Waterman score: 3142; 95.2% identity (95.2% similar) in 484 aa overlap (1-461:1-484)
10 20 30 40 50 60
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
310 320 330 340 350 360
370 380 390
pF1KE1 ARASTGSS-----------------------DSSPGGHGTQVNVTCIVNVCSSSDHSSQC
:::::::: :::::::::::::::::::::::::::::
XP_011 ARASTGSSGLSDCMYRHCLLLSPTPGCGTPADSSPGGHGTQVNVTCIVNVCSSSDHSSQC
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE1 SSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAG
430 440 450 460 470 480
460
pF1KE1 MKPS
::::
XP_011 MKPS
>>XP_016857700 (OMIM: 191191) PREDICTED: tumor necrosis (491 aa)
initn: 2133 init1: 2133 opt: 2133 Z-score: 1464.4 bits: 280.3 E(85289): 7.9e-75
Smith-Waterman score: 2133; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300)
10 20 30 40 50 60
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
XP_016 VSVSTALSPSSPGLLPGVLGCHRGSSEFCHWSVQCQEVCRALGGGGKAGESGSPPWAKRG
310 320 330 340 350 360
>>XP_016857702 (OMIM: 191191) PREDICTED: tumor necrosis (440 aa)
initn: 1784 init1: 1784 opt: 1784 Z-score: 1228.2 bits: 236.5 E(85289): 1.1e-61
Smith-Waterman score: 1784; 100.0% identity (100.0% similar) in 249 aa overlap (52-300:1-249)
30 40 50 60 70 80
pF1KE1 ALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
::::::::::::::::::::::::::::::
XP_016 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
10 20 30
90 100 110 120 130 140
pF1KE1 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCT
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 STSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALP
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 VGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLI
:::::::::::::::::::::::::::::::::::::::
XP_016 VGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVVSVSTALSPSSPGLLPGVLGC
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 TAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVNV
XP_016 HRGSSEFCHWSVQCQEVCRALGGGGKAGESGSPPWAKRGCECEMLRQRADAFVAFVAGTW
280 290 300 310 320 330
>>XP_016857701 (OMIM: 191191) PREDICTED: tumor necrosis (440 aa)
initn: 1784 init1: 1784 opt: 1784 Z-score: 1228.2 bits: 236.5 E(85289): 1.1e-61
Smith-Waterman score: 1784; 100.0% identity (100.0% similar) in 249 aa overlap (52-300:1-249)
30 40 50 60 70 80
pF1KE1 ALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
::::::::::::::::::::::::::::::
XP_016 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDS
10 20 30
90 100 110 120 130 140
pF1KE1 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLR
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCT
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 STSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALP
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 VGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLI
:::::::::::::::::::::::::::::::::::::::
XP_016 VGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVVSVSTALSPSSPGLLPGVLGC
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 TAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVNV
XP_016 HRGSSEFCHWSVQCQEVCRALGGGGKAGESGSPPWAKRGCECEMLRQRADAFVAFVAGTW
280 290 300 310 320 330
>>XP_016857704 (OMIM: 191191) PREDICTED: tumor necrosis (266 aa)
initn: 1763 init1: 1763 opt: 1763 Z-score: 1217.2 bits: 233.7 E(85289): 4.6e-61
Smith-Waterman score: 1763; 100.0% identity (100.0% similar) in 266 aa overlap (196-461:1-266)
170 180 190 200 210 220
pF1KE1 PGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQ
::::::::::::::::::::::::::::::
XP_016 MDAVCTSTSPTRSMAPGAVHLPQPVSTRSQ
10 20 30
230 240 250 260 270 280
pF1KE1 HTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMT
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE1 QVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTR
100 110 120 130 140 150
350 360 370 380 390 400
pF1KE1 NQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTM
160 170 180 190 200 210
410 420 430 440 450 460
pF1KE1 GDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
220 230 240 250 260
>>XP_016857703 (OMIM: 191191) PREDICTED: tumor necrosis (289 aa)
initn: 1197 init1: 1135 opt: 1135 Z-score: 790.3 bits: 154.8 E(85289): 2.8e-37
Smith-Waterman score: 1707; 92.0% identity (92.0% similar) in 289 aa overlap (196-461:1-289)
170 180 190 200 210 220
pF1KE1 PGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQ
::::::::::::::::::::::::::::::
XP_016 MDAVCTSTSPTRSMAPGAVHLPQPVSTRSQ
10 20 30
230 240 250 260 270 280
pF1KE1 HTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMT
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE1 QVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTR
100 110 120 130 140 150
350 360 370 380
pF1KE1 NQPQAPGVEASGAGEARASTGSS-----------------------DSSPGGHGTQVNVT
::::::::::::::::::::::: ::::::::::::::
XP_016 NQPQAPGVEASGAGEARASTGSSGLSDCMYRHCLLLSPTPGCGTPADSSPGGHGTQVNVT
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE1 CIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLG
220 230 240 250 260 270
450 460
pF1KE1 STEEKPLPLGVPDAGMKPS
:::::::::::::::::::
XP_016 STEEKPLPLGVPDAGMKPS
280
>>XP_005253745 (OMIM: 600979) PREDICTED: tumor necrosis (399 aa)
initn: 341 init1: 199 opt: 487 Z-score: 348.3 bits: 73.5 E(85289): 1.2e-12
Smith-Waterman score: 492; 30.1% identity (53.6% similar) in 366 aa overlap (2-352:9-340)
10 20 30 40 50
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCR--LREYYDQTAQ
:: .:. :..:: :: . : : ::: : ..::: .:::. .
XP_005 MLLPWATSAPGLAWGPLVLGLFGLLAA-SQPQAVP--PYASE-NQTCRDQEKEYYEPQHR
10 20 30 40 50
60 70 80 90 100
pF1KE1 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQV----ET
.:::.: :: .... :.. :::: .: ...:.. ::.. : : : : : :
XP_005 ICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLC-RPC--DPVMGLEEI
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 QACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVA-RPGTETSDVVCKPCAP
:: ... : :.:: .:: : : : : : :: . . . .. : ::
XP_005 APCTSKRKTQCRCQPGMFCAAWALE-CTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 GTFSNTTSSTDICRPHQICN----VVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVST
: :.::.: . :.:: :. : : ::.:. :..: . : . . : . ..
XP_005 GHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKN--PLEPLPPEMS--GSLLKR
180 190 200 210 220
230 240 250 260 270
pF1KE1 RSQHTQPTP-EPSTAPSTSFLLPMGPS--PPAEGSTGDFALPVGLIVGVTALGLLIIGVV
: : :.: : : . :. :. : .:: . ::. .:. : .: ::
XP_005 RPQGEGPNPVAGSWEPPKAH--PYFPDLVQPLLPISGDVS-PVS--TGLPAAPVLEAGVP
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE1 NCVIMTQVKKKPLCLQREAKVPHL-PADKARGTQGPEQQHLLITAPSSSSSSLESSASAL
. ...:: : :: :.: :..... ..: . :. ...:. ...
XP_005 Q-------QQSPLDLTRE---PQLEPGEQSQVAHGTNGIHV-------TGGSMTITGNIY
290 300 310 320
340 350 360 370 380 390
pF1KE1 DRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCS
.:. . : .::
XP_005 IYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQEDGKAWHLAETEHCGATP
330 340 350 360 370 380
>>NP_003814 (OMIM: 603361) tumor necrosis factor recepto (300 aa)
initn: 446 init1: 234 opt: 472 Z-score: 339.9 bits: 71.6 E(85289): 3.4e-12
Smith-Waterman score: 472; 34.8% identity (58.1% similar) in 210 aa overlap (13-213:8-208)
10 20 30 40 50
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKC
:: : . :::: . : : : : : .. . :..:
NP_003 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQC
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 SPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRI
:: .. : . : :.: : :::.::.. .: :. :. . :..:: .::
NP_003 PPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 CTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTD
: :: :.. . : .: .: :: :: ::: .... :.:: ::::: ..::..
NP_003 CRCRTGFFA----HAG--FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSE
120 130 140 150 160
180 190 200 210 220 230
pF1KE1 ICRPHQICNVVA----IPGNASMDAVCTSTS--PTRSMAPGAVHLPQPVSTRSQHTQPTP
:.::. :.... .::..: :..::: . : . .:::
NP_003 QCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISI
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 EPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKP
NP_003 KRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMP
230 240 250 260 270 280
461 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:30:18 2016 done: Sun Nov 6 19:30:20 2016
Total Scan time: 11.660 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]