Result of FASTA (ccds) for
pFN21AE1924
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1924, 461 aa
1>>>pF1KE1924 461 - 461 aa - 461 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5091+/-0.000895; mu= 5.4073+/- 0.054
mean_var=209.6572+/-40.817, 0's: 0 Z-trim(115.0): 34 B-trim: 6 in 1/50
Lambda= 0.088577
statistics sampled from 15477 (15511) to 15477 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.476), width: 16
Scan time: 3.800
The best scores are: opt bits E(32554)
CCDS145.1 TNFRSF1B gene_id:7133|Hs108|chr1 ( 461) 3198 420.9 1.4e-117
CCDS13532.1 TNFRSF6B gene_id:8771|Hs108|chr20 ( 300) 472 72.4 7.2e-13
CCDS6326.1 TNFRSF11B gene_id:4982|Hs108|chr8 ( 401) 455 70.3 4e-12
CCDS8544.1 LTBR gene_id:4055|Hs108|chr12 ( 435) 451 69.9 6.1e-12
CCDS59233.1 LTBR gene_id:4055|Hs108|chr12 ( 416) 437 68.0 2e-11
CCDS13393.1 CD40 gene_id:958|Hs108|chr20 ( 277) 429 66.9 3.1e-11
>>CCDS145.1 TNFRSF1B gene_id:7133|Hs108|chr1 (461 aa)
initn: 3198 init1: 3198 opt: 3198 Z-score: 2224.6 bits: 420.9 E(32554): 1.4e-117
Smith-Waterman score: 3198; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)
10 20 30 40 50 60
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 PHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 FLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 PHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQ
370 380 390 400 410 420
430 440 450 460
pF1KE1 VPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
:::::::::::::::::::::::::::::::::::::::::
CCDS14 VPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
430 440 450 460
>>CCDS13532.1 TNFRSF6B gene_id:8771|Hs108|chr20 (300 aa)
initn: 446 init1: 234 opt: 472 Z-score: 344.5 bits: 72.4 E(32554): 7.2e-13
Smith-Waterman score: 472; 34.8% identity (58.1% similar) in 210 aa overlap (13-213:8-208)
10 20 30 40 50
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQV---AFTPYAPEPGSTCRLREYYDQTAQMCCSKC
:: : . :::: . : : : : : .. . :..:
CCDS13 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGER---LVCAQC
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 SPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRI
:: .. : . : :.: : :::.::.. .: :. :. . :..:: .::
CCDS13 PPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 CTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTD
: :: :.. . : .: .: :: :: ::: .... :.:: ::::: ..::..
CCDS13 CRCRTGFFA----HAG--FCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSE
120 130 140 150 160
180 190 200 210 220 230
pF1KE1 ICRPHQICNVVA----IPGNASMDAVCTSTS--PTRSMAPGAVHLPQPVSTRSQHTQPTP
:.::. :.... .::..: :..::: . : . .:::
CCDS13 QCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISI
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 EPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKP
CCDS13 KRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMP
230 240 250 260 270 280
>>CCDS6326.1 TNFRSF11B gene_id:4982|Hs108|chr8 (401 aa)
initn: 436 init1: 261 opt: 455 Z-score: 331.1 bits: 70.3 E(32554): 4e-12
Smith-Waterman score: 455; 39.3% identity (57.7% similar) in 168 aa overlap (45-206:30-191)
20 30 40 50 60 70
pF1KE1 ELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQ--TAQMCCSKCSPGQHAKVFCTKTSD
.::. . :. :.:: :: . : ::
CCDS63 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWK
10 20 30 40 50
80 90 100 110 120 130
pF1KE1 TVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQE
::: : : ::. :. ::: :. :. : : :.: .::.: :. : : .
CCDS63 TVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEI----
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE1 GCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAI--
..: :.: :::::.. :: ..::: : : ::: ::: :: : :.: ..
CCDS63 --EFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLL
120 130 140 150 160 170
200 210 220 230 240
pF1KE1 --PGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPS
:::. : .:...: .
CCDS63 TQKGNATHDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVN
180 190 200 210 220 230
>>CCDS8544.1 LTBR gene_id:4055|Hs108|chr12 (435 aa)
initn: 341 init1: 199 opt: 451 Z-score: 327.8 bits: 69.9 E(32554): 6.1e-12
Smith-Waterman score: 472; 29.7% identity (52.9% similar) in 391 aa overlap (2-352:9-376)
10 20 30 40 50
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCR--LREYYDQTAQ
:: .:. :..:: :: . : : ::: : ..::: .:::. .
CCDS85 MLLPWATSAPGLAWGPLVLGLFGLLAA-SQPQAVP--PYASE-NQTCRDQEKEYYEPQHR
10 20 30 40 50
60 70 80 90 100
pF1KE1 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQV----ET
.:::.: :: .... :.. :::: .: ...:.. ::.. : : : : : :
CCDS85 ICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLC-RPC--DPVMGLEEI
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 QACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVA-RPGTETSDVVCKPCAP
:: ... : :.:: .:: : : : : : :: . . . .. : ::
CCDS85 APCTSKRKTQCRCQPGMFCAAWALE-CTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKA
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 GTFSNTTSSTDICRPHQICN----VVAIPGNASMDAVCTSTSPTRSMAP---G-----AV
: :.::.: . :.:: :. : : ::.:. :..: .: . . : : ::
CCDS85 GHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCK--NPLEPLPPEMSGTMLMLAV
180 190 200 210 220 230
220 230 240 250
pF1KE1 HLPQP----VSTRSQHTQPTPEPSTAPSTSFLL---PMGPSP-PAEGS---------TGD
:: ..: . . .:: . . :: :.: .: :. :: :
CCDS85 LLPLAFFLLLATVFSCIWKS-HPSLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPD
240 250 260 270 280
260 270 280 290 300 310
pF1KE1 FA---LPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHL-PADKARGTQG
.. ::.. :. .. :: :.. . : ..:: : :: :.: :..... ..:
CCDS85 LVQPLLPISGDVSPVSTGLPAAPVLEAGVPQQ--QSPLDLTRE---PQLEPGEQSQVAHG
290 300 310 320 330 340
320 330 340 350 360 370
pF1KE1 PEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPG
. :. ...:. ... .:. . : .::
CCDS85 TNGIHV-------TGGSMTITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPP
350 360 370 380 390
380 390 400 410 420 430
pF1KE1 GHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQ
CCDS85 GLSTPHQEDGKAWHLAETEHCGATPSNRGPRNQFITHD
400 410 420 430
>>CCDS59233.1 LTBR gene_id:4055|Hs108|chr12 (416 aa)
initn: 341 init1: 199 opt: 437 Z-score: 318.4 bits: 68.0 E(32554): 2e-11
Smith-Waterman score: 458; 29.1% identity (53.3% similar) in 375 aa overlap (18-352:3-357)
10 20 30 40 50
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCR--LREYYDQTAQMCCSKCS
:.. .: .:. ::: : ..::: .:::. ..:::.:
CCDS59 MEATGISLASQLKVPPYASE-NQTCRDQEKEYYEPQHRICCSRCP
10 20 30 40
60 70 80 90 100 110
pF1KE1 PGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQV----ETQACTREQ
:: .... :.. :::: .: ...:.. ::.. : : : : : : :: ..
CCDS59 PGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLC-RPC--DPVMGLEEIAPCTSKR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 NRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVA-RPGTETSDVVCKPCAPGTFSNTT
. : :.:: .:: : : : : : :: . . . .. : :: : :.::.
CCDS59 KTQCRCQPGMFCAAWALE-CTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTS
110 120 130 140 150 160
180 190 200 210
pF1KE1 SSTDICRPHQICN----VVAIPGNASMDAVCTSTSPTRSMAP---G-----AVHLPQP--
: . :.:: :. : : ::.:. :..: . : . . : : :: ::
CCDS59 SPSARCQPHTRCENQGLVEAAPGTAQSDTTCKN--PLEPLPPEMSGTMLMLAVLLPLAFF
170 180 190 200 210
220 230 240 250 260
pF1KE1 --VSTRSQHTQPTPEPSTAPSTSFLL---PMGPSP-PAEGS---------TGDFA---LP
..: . . .:: . . :: :.: .: :. :: :.. ::
CCDS59 LLLATVFSCIWKS-HPSLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLP
220 230 240 250 260 270
270 280 290 300 310 320
pF1KE1 VGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHL-PADKARGTQGPEQQHLL
.. :. .. :: :.. . : ..:: : :: :.: :..... ..: . :.
CCDS59 ISGDVSPVSTGLPAAPVLEAGVPQQ--QSPLDLTRE---PQLEPGEQSQVAHGTNGIHV-
280 290 300 310 320 330
330 340 350 360 370 380
pF1KE1 ITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVN
...:. ... .:. . : .::
CCDS59 ------TGGSMTITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQ
340 350 360 370 380
390 400 410 420 430 440
pF1KE1 VTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETL
CCDS59 EDGKAWHLAETEHCGATPSNRGPRNQFITHD
390 400 410
>>CCDS13393.1 CD40 gene_id:958|Hs108|chr20 (277 aa)
initn: 340 init1: 167 opt: 429 Z-score: 315.3 bits: 66.9 E(32554): 3.1e-11
Smith-Waterman score: 429; 35.1% identity (61.2% similar) in 188 aa overlap (29-209:15-195)
10 20 30 40 50 60
pF1KE1 MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPG
.: ::: ..:: ..: ..::: :.::
CCDS13 MVRLPLQCVLWGCLLTAVHPEPPTACREKQYL--INSQCCSLCQPG
10 20 30 40
70 80 90 100 110
pF1KE1 QHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSD---QVETQACTREQNRI
:. ::. ..: : : .: . . :: .: . . :. . .:. : : : . :
CCDS13 QKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQ-HKYCDPNLGLRVQ-QKGTSETDTI
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 CTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTD
:::. ::.:. .:.:. :. :.: ::::: . .: .::..:.:: : :::..:. .
CCDS13 CTCEEGWHCT---SEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFE
110 120 130 140 150
180 190 200 210 220 230
pF1KE1 ICRPHQICN----VVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEP
:.: :. :: :. . :.:: . :..
CCDS13 KCHPWTSCETKDLVVQQAGTNKTDVVCGPQDRLRALVVIPIIFGILFAILLVLVFIKKVA
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 STAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLC
CCDS13 KKPTNKAPHPKQEPQEINFPDDLPGSNTAAPVQETLHGCQPVTQEDGKESRISVQERQ
220 230 240 250 260 270
461 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:30:17 2016 done: Sun Nov 6 19:30:18 2016
Total Scan time: 3.800 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]