Result of FASTA (omim) for
pFN21AE1915
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1915, 452 aa
1>>>pF1KE1915 452 - 452 aa - 452 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1835+/-0.000375; mu= 12.8025+/- 0.023
mean_var=77.5282+/-15.681, 0's: 0 Z-trim(114.2): 95 B-trim: 525 in 1/55
Lambda= 0.145661
statistics sampled from 23848 (23945) to 23848 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.281), width: 16
Scan time: 8.390
The best scores are: opt bits E(85289)
NP_116764 (OMIM: 600639) caspase-2 isoform 1 prepr ( 452) 3090 659.0 7.2e-189
NP_001215 (OMIM: 600639) caspase-2 isoform 2 [Homo ( 312) 1954 420.2 3.8e-117
NP_116765 (OMIM: 600639) caspase-2 isoform 3 [Homo ( 108) 694 155.3 7.4e-38
NP_001220 (OMIM: 602234) caspase-9 isoform alpha p ( 416) 437 101.5 4.5e-21
XP_011540575 (OMIM: 602234) PREDICTED: caspase-9 i ( 421) 437 101.5 4.5e-21
XP_005246951 (OMIM: 114480,114550,211980,601763,60 ( 280) 427 99.3 1.4e-20
XP_011510271 (OMIM: 114480,114550,211980,601763,60 ( 334) 421 98.1 3.8e-20
XP_005246949 (OMIM: 114480,114550,211980,601763,60 ( 464) 421 98.1 5.1e-20
NP_001073593 (OMIM: 114480,114550,211980,601763,60 ( 464) 421 98.1 5.1e-20
NP_203520 (OMIM: 114480,114550,211980,601763,60727 ( 464) 421 98.1 5.1e-20
XP_005246945 (OMIM: 114480,114550,211980,601763,60 ( 479) 421 98.2 5.2e-20
NP_203519 (OMIM: 114480,114550,211980,601763,60727 ( 479) 421 98.2 5.2e-20
XP_005246948 (OMIM: 114480,114550,211980,601763,60 ( 479) 421 98.2 5.2e-20
XP_005246943 (OMIM: 114480,114550,211980,601763,60 ( 479) 421 98.2 5.2e-20
XP_005246944 (OMIM: 114480,114550,211980,601763,60 ( 479) 421 98.2 5.2e-20
XP_005246946 (OMIM: 114480,114550,211980,601763,60 ( 479) 421 98.2 5.2e-20
XP_006712852 (OMIM: 114480,114550,211980,601763,60 ( 479) 421 98.2 5.2e-20
XP_005246947 (OMIM: 114480,114550,211980,601763,60 ( 479) 421 98.2 5.2e-20
XP_006712853 (OMIM: 114480,114550,211980,601763,60 ( 479) 421 98.2 5.2e-20
NP_001219 (OMIM: 114480,114550,211980,601763,60727 ( 496) 421 98.2 5.4e-20
XP_005246942 (OMIM: 114480,114550,211980,601763,60 ( 523) 421 98.2 5.7e-20
NP_001073594 (OMIM: 114480,114550,211980,601763,60 ( 538) 421 98.2 5.8e-20
NP_001217 (OMIM: 601532) caspase-6 isoform alpha p ( 293) 391 91.8 2.7e-18
NP_001244047 (OMIM: 147678) caspase-1 isoform alph ( 404) 368 87.0 1e-16
NP_150634 (OMIM: 147678) caspase-1 isoform alpha p ( 404) 368 87.0 1e-16
XP_005246071 (OMIM: 602234) PREDICTED: caspase-9 i ( 333) 365 86.3 1.3e-16
NP_127463 (OMIM: 602234) caspase-9 isoform 3 [Homo ( 333) 365 86.3 1.3e-16
NP_150635 (OMIM: 147678) caspase-1 isoform gamma [ ( 311) 363 85.9 1.7e-16
XP_016873885 (OMIM: 147678) PREDICTED: caspase-1 i ( 374) 363 85.9 2e-16
XP_016873884 (OMIM: 147678) PREDICTED: caspase-1 i ( 380) 363 85.9 2e-16
NP_001244048 (OMIM: 147678) caspase-1 isoform beta ( 383) 363 85.9 2e-16
NP_001214 (OMIM: 147678) caspase-1 isoform beta pr ( 383) 363 85.9 2e-16
XP_016873882 (OMIM: 147678) PREDICTED: caspase-1 i ( 401) 363 85.9 2.1e-16
XP_016873883 (OMIM: 147678) PREDICTED: caspase-1 i ( 401) 363 85.9 2.1e-16
NP_001193471 (OMIM: 601762,603909,605027,613659) c ( 478) 327 78.4 4.6e-14
NP_001221 (OMIM: 601762,603909,605027,613659) casp ( 479) 327 78.4 4.6e-14
XP_006712859 (OMIM: 601762,603909,605027,613659) P ( 272) 321 77.1 6.7e-14
XP_005246964 (OMIM: 601762,603909,605027,613659) P ( 521) 321 77.1 1.2e-13
NP_116756 (OMIM: 601762,603909,605027,613659) casp ( 521) 321 77.1 1.2e-13
NP_116759 (OMIM: 601762,603909,605027,613659) casp ( 522) 321 77.1 1.2e-13
NP_150636 (OMIM: 147678) caspase-1 isoform delta [ ( 263) 316 76.0 1.3e-13
NP_001129582 (OMIM: 602665) caspase-5 isoform c [H ( 292) 316 76.0 1.5e-13
NP_001129581 (OMIM: 602665) caspase-5 isoform b pr ( 376) 316 76.1 1.9e-13
XP_016873886 (OMIM: 602664) PREDICTED: caspase-4 i ( 286) 314 75.6 1.9e-13
XP_011541321 (OMIM: 602664) PREDICTED: caspase-4 i ( 286) 314 75.6 1.9e-13
NP_004338 (OMIM: 602665) caspase-5 isoform a precu ( 434) 316 76.1 2.1e-13
NP_150649 (OMIM: 602664) caspase-4 isoform gamma p ( 321) 314 75.6 2.1e-13
NP_001129584 (OMIM: 602665) caspase-5 isoform f pr ( 447) 316 76.1 2.2e-13
NP_001177945 (OMIM: 608633) inactive caspase-12 [H ( 341) 314 75.6 2.3e-13
NP_001216 (OMIM: 602664) caspase-4 isoform alpha p ( 377) 314 75.6 2.5e-13
>>NP_116764 (OMIM: 600639) caspase-2 isoform 1 prepropro (452 aa)
initn: 3090 init1: 3090 opt: 3090 Z-score: 3511.8 bits: 659.0 E(85289): 7.2e-189
Smith-Waterman score: 3090; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452)
10 20 30 40 50 60
pF1KE1 MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 PEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 HVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 HVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 RSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 RSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGY
370 380 390 400 410 420
430 440 450
pF1KE1 APGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
::::::::::::::::::::::::::::::::
NP_116 APGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
430 440 450
>>NP_001215 (OMIM: 600639) caspase-2 isoform 2 [Homo sap (312 aa)
initn: 1954 init1: 1954 opt: 1954 Z-score: 2224.2 bits: 420.2 E(85289): 3.8e-117
Smith-Waterman score: 1954; 100.0% identity (100.0% similar) in 291 aa overlap (32-322:1-291)
10 20 30 40 50 60
pF1KE1 AAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHLL
::::::::::::::::::::::::::::::
NP_001 MHPHHQETLKKNRVVLAKQLLLSELLEHLL
10 20 30
70 80 90 100 110 120
pF1KE1 EKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLTT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 LSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCTP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 EFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVH
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 VLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 NANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTR
:::::::::::::::::::::
NP_001 NANCPSLQNKPKMFFIQACRGGAIGSLGHLLLFTAATASLAL
280 290 300 310
>>NP_116765 (OMIM: 600639) caspase-2 isoform 3 [Homo sap (108 aa)
initn: 694 init1: 694 opt: 694 Z-score: 800.7 bits: 155.3 E(85289): 7.4e-38
Smith-Waterman score: 694; 100.0% identity (100.0% similar) in 106 aa overlap (1-106:1-106)
10 20 30 40 50 60
pF1KE1 MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLT
::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALHS
70 80 90 100
130 140 150 160 170 180
pF1KE1 TLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCT
>>NP_001220 (OMIM: 602234) caspase-9 isoform alpha precu (416 aa)
initn: 308 init1: 200 opt: 437 Z-score: 499.3 bits: 101.5 E(85289): 4.5e-21
Smith-Waterman score: 548; 31.3% identity (59.0% similar) in 422 aa overlap (32-430:1-410)
10 20 30 40 50 60
pF1KE1 AAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHLL
: .. :.. :. :...: ...: . ::
NP_001 MDEADRRLLRRCRLRLVEELQVDQLWDALL
10 20 30
70 80 90 100 110
pF1KE1 EKDIITLEMRELIQAKVGSFS---QNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDML
.... .: : :: ..:: : : .:. : :: ::. : :..: : : ..:
NP_001 SRELFRPHMIEDIQ-RAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFL
40 50 60 70 80
120 130 140 150 160 170
pF1KE1 LTTLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKP
:. .. . : : .:. :: : .: .. . . .: .: .:
NP_001 RTNRQAAKLSKPTLE---NLT---PVVLR-PEIRKPEVLRPETPRPVDIGSGGFG-DVGA
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE1 CTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGY
: . . .::: :. .: : :...::.: :. :. :.:...: : :. : .
NP_001 L--ESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHF
150 160 170 180 190
240 250 260 270 280 290
pF1KE1 DVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVE-------GAIYGVDGKLL
:.: : ::..: : ..:: : . : :.:..:::: . ::.::.:: .
NP_001 MVEVKGDLTAKKMVLALLELAQ-QDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPV
200 210 220 230 240 250
300 310 320 330 340
pF1KE1 QLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCE-ESDA--
..... ..:....:::: .:::.:::::: :.. :.: . . . . ::: . : ::
NP_001 SVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATP
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE1 ---GKEKLPKM----RLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDM
: . . .. ::: ::.. .:. . : .. :. : ::::.:.: ..: . : .
NP_001 FQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSE
320 330 340 350 360 370
410 420 430 440 450
pF1KE1 HVADMLVKV-NAL-IKDREGYAPGT-EFHRCKEMSEYCSTLCRHLYLFPGHPPT
. ..:..: ::. .: :: .: : :
NP_001 DLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
380 390 400 410
>>XP_011540575 (OMIM: 602234) PREDICTED: caspase-9 isofo (421 aa)
initn: 308 init1: 200 opt: 437 Z-score: 499.2 bits: 101.5 E(85289): 4.5e-21
Smith-Waterman score: 546; 31.2% identity (59.9% similar) in 401 aa overlap (32-412:1-389)
10 20 30 40 50 60
pF1KE1 AAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHLL
: .. :.. :. :...: ...: . ::
XP_011 MDEADRRLLRRCRLRLVEELQVDQLWDALL
10 20 30
70 80 90 100 110
pF1KE1 EKDIITLEMRELIQAKVGSFS---QNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDML
.... .: : :: ..:: : : .:. : :: ::. : :..: : : ..:
XP_011 SRELFRPHMIEDIQ-RAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFL
40 50 60 70 80
120 130 140 150 160 170
pF1KE1 LTTLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKP
:. .. . : : .:. :: : .: .. . . .: .: .:
XP_011 RTNRQAAKLSKPTLE---NLT---PVVLR-PEIRKPEVLRPETPRPVDIGSGGFG-DVGA
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE1 CTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGY
: . . .::: :. .: : :...::.: :. :. :.:...: : :. : .
XP_011 L--ESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHF
150 160 170 180 190
240 250 260 270 280 290
pF1KE1 DVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVE-------GAIYGVDGKLL
:.: : ::..: : ..:: : . : :.:..:::: . ::.::.:: .
XP_011 MVEVKGDLTAKKMVLALLELAQQD-HGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPV
200 210 220 230 240 250
300 310 320 330 340
pF1KE1 QLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCE-ESDA--
..... ..:....:::: .:::.:::::: :.. :.: . . . . ::: . : ::
XP_011 SVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATP
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE1 ---GKEKLPKM----RLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDM
: . . .. ::: ::.. .:. . : .. :. : ::::.:.: ..: . : .
XP_011 FQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSE
320 330 340 350 360 370
410 420 430 440 450
pF1KE1 HVADMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
. ..:..:.:
XP_011 DLQSLLLRVSAAFLCKGEGRLLRGSVSSWGWGFGVSRAGPNQG
380 390 400 410 420
>>XP_005246951 (OMIM: 114480,114550,211980,601763,607271 (280 aa)
initn: 360 init1: 227 opt: 427 Z-score: 490.7 bits: 99.3 E(85289): 1.4e-20
Smith-Waterman score: 429; 30.3% identity (62.8% similar) in 274 aa overlap (184-447:19-278)
160 170 180 190 200 210
pF1KE1 LRLSTDTVEHSLDNKDGPVCLQVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGE
.: .. .:...:.::: :...: .:.
XP_005 MKNSAKREAAALKEVLMNFQMTLDKVYQMKSKPRGYCLIINNHNFAKA
10 20 30 40
220 230 240 250 260
pF1KE1 KE-------LEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRV
.: .. :.: .: ..:.: :. : .... : :.... : :. . :: :
XP_005 REKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIY-QLMDHSN
50 60 70 80 90 100
270 280 290 300 310 320
pF1KE1 TDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETD
: : .:::: .: :::.::. . :. . : . .:::: .:::.::::::.::. .
XP_005 MDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQ
110 120 130 140 150 160
330 340 350 360 370 380
pF1KE1 RGVDQQDGKNHAGSPGCEESDAGKEKLPKMR-LPTRSDMICGYACLKGTAAMRNTKRGSW
.:. . ... .: : . .. :. : .: ..:.. :.: ... ...:: .:.:
XP_005 KGIPVETDSEE--QPYLEMDLSS----PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTW
170 180 190 200 210 220
390 400 410 420 430 440
pF1KE1 YIEALAQVFSERACDM--HVADMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHL
::..: : . :: : . .:..:: ..... . :.: . :: ..:
XP_005 YIQSLCQSLRER-CPRGDDILTILTEVNYEVSNKDDKK-----NMGKQMPQPTFTLRKKL
230 240 250 260 270
450
pF1KE1 YLFPGHPPT
.::
XP_005 -VFPSD
280
>>XP_011510271 (OMIM: 114480,114550,211980,601763,607271 (334 aa)
initn: 360 init1: 227 opt: 421 Z-score: 482.7 bits: 98.1 E(85289): 3.8e-20
Smith-Waterman score: 423; 30.8% identity (63.2% similar) in 266 aa overlap (192-447:81-332)
170 180 190 200 210
pF1KE1 EHSLDNKDGPVCLQVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKE------
:...:.::: :...: .:. .:
XP_011 FSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLH
60 70 80 90 100 110
220 230 240 250 260 270
pF1KE1 -LEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVAL
.. :.: .: ..:.: :. : .... : :.... : :. . :: : : : .
XP_011 SIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIY-QLMDHSNMDCFICCI
120 130 140 150 160
280 290 300 310 320 330
pF1KE1 LSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDG
:::: .: :::.::. . :. . : . .:::: .:::.::::::.::. ..:. .
XP_011 LSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETD
170 180 190 200 210 220
340 350 360 370 380 390
pF1KE1 KNHAGSPGCEESDAGKEKLPKMR-LPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQV
... .: : . .. :. : .: ..:.. :.: ... ...:: .:.:::..: :
XP_011 SEE--QPYLEMDLSS----PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQS
230 240 250 260 270 280
400 410 420 430 440 450
pF1KE1 FSERACDM--HVADMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPP
. :: : . .:..:: ..... . . :.: . :: ..: .::
XP_011 LRER-CPRGDDILTILTEVNYEVSNKD-----DKKNMGKQMPQPTFTLRKKL-VFPSD
290 300 310 320 330
pF1KE1 T
>>XP_005246949 (OMIM: 114480,114550,211980,601763,607271 (464 aa)
initn: 321 init1: 227 opt: 421 Z-score: 480.4 bits: 98.1 E(85289): 5.1e-20
Smith-Waterman score: 424; 28.8% identity (61.0% similar) in 313 aa overlap (148-447:164-462)
120 130 140 150 160 170
pF1KE1 LLTTLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKK--LRLSTDTVEHSLDNKD-GPVCL
: .: :.. .: : : .. : . .
XP_005 DDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKGEELCGVMTI
140 150 160 170 180 190
180 190 200 210 220
pF1KE1 QVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKE-------LEFRSGGDVDHS
. .: . . .. .:...:.::: :...: .:. .: .. :.: .: .
XP_005 SDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE1 TLVTLFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVD
.:.: :. : .... : :.... : :. . :: : : : .:::: .: :::.:
XP_005 ALTTTFEELHFEIKPHDDCTVEQIYEILKIY-QLMDHSNMDCFICCILSHGDKGIIYGTD
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE1 GKLLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESD
:. . :. . : . .:::: .:::.::::::.::. ..:. . ... .: : .
XP_005 GQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEE--QPYLEMDL
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE1 AGKEKLPKMR-LPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDM--HVA
.. :. : .: ..:.. :.: ... ...:: .:.:::..: : . :: : .
XP_005 SS----PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRER-CPRGDDIL
380 390 400 410 420
410 420 430 440 450
pF1KE1 DMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
.:..:: ..... . . :.: . :: ..: .::
XP_005 TILTEVNYEVSNKD-----DKKNMGKQMPQPTFTLRKKL-VFPSD
430 440 450 460
>>NP_001073593 (OMIM: 114480,114550,211980,601763,607271 (464 aa)
initn: 321 init1: 227 opt: 421 Z-score: 480.4 bits: 98.1 E(85289): 5.1e-20
Smith-Waterman score: 424; 28.8% identity (61.0% similar) in 313 aa overlap (148-447:164-462)
120 130 140 150 160 170
pF1KE1 LLTTLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKK--LRLSTDTVEHSLDNKD-GPVCL
: .: :.. .: : : .. : . .
NP_001 DDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKGEELCGVMTI
140 150 160 170 180 190
180 190 200 210 220
pF1KE1 QVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKE-------LEFRSGGDVDHS
. .: . . .. .:...:.::: :...: .:. .: .. :.: .: .
NP_001 SDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE1 TLVTLFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVD
.:.: :. : .... : :.... : :. . :: : : : .:::: .: :::.:
NP_001 ALTTTFEELHFEIKPHDDCTVEQIYEILKIY-QLMDHSNMDCFICCILSHGDKGIIYGTD
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE1 GKLLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESD
:. . :. . : . .:::: .:::.::::::.::. ..:. . ... .: : .
NP_001 GQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEE--QPYLEMDL
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE1 AGKEKLPKMR-LPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDM--HVA
.. :. : .: ..:.. :.: ... ...:: .:.:::..: : . :: : .
NP_001 SS----PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRER-CPRGDDIL
380 390 400 410 420
410 420 430 440 450
pF1KE1 DMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
.:..:: ..... . . :.: . :: ..: .::
NP_001 TILTEVNYEVSNKD-----DKKNMGKQMPQPTFTLRKKL-VFPSD
430 440 450 460
>>NP_203520 (OMIM: 114480,114550,211980,601763,607271) c (464 aa)
initn: 321 init1: 227 opt: 421 Z-score: 480.4 bits: 98.1 E(85289): 5.1e-20
Smith-Waterman score: 424; 28.8% identity (61.0% similar) in 313 aa overlap (148-447:164-462)
120 130 140 150 160 170
pF1KE1 LLTTLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKK--LRLSTDTVEHSLDNKD-GPVCL
: .: :.. .: : : .. : . .
NP_203 DDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKGEELCGVMTI
140 150 160 170 180 190
180 190 200 210 220
pF1KE1 QVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKE-------LEFRSGGDVDHS
. .: . . .. .:...:.::: :...: .:. .: .. :.: .: .
NP_203 SDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE1 TLVTLFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVD
.:.: :. : .... : :.... : :. . :: : : : .:::: .: :::.:
NP_203 ALTTTFEELHFEIKPHDDCTVEQIYEILKIY-QLMDHSNMDCFICCILSHGDKGIIYGTD
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE1 GKLLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESD
:. . :. . : . .:::: .:::.::::::.::. ..:. . ... .: : .
NP_203 GQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEE--QPYLEMDL
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE1 AGKEKLPKMR-LPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDM--HVA
.. :. : .: ..:.. :.: ... ...:: .:.:::..: : . :: : .
NP_203 SS----PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRER-CPRGDDIL
380 390 400 410 420
410 420 430 440 450
pF1KE1 DMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
.:..:: ..... . . :.: . :: ..: .::
NP_203 TILTEVNYEVSNKD-----DKKNMGKQMPQPTFTLRKKL-VFPSD
430 440 450 460
452 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:01:33 2016 done: Sun Nov 6 22:01:34 2016
Total Scan time: 8.390 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]