Result of FASTA (omim) for
pFN21AE1898
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1898, 824 aa
1>>>pF1KE1898 824 - 824 aa - 824 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0567+/-0.000419; mu= 12.8507+/- 0.026
mean_var=153.3756+/-29.021, 0's: 0 Z-trim(116.2): 199 B-trim: 29 in 1/53
Lambda= 0.103561
statistics sampled from 26921 (27171) to 26921 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.319), width: 16
Scan time: 7.790
The best scores are: opt bits E(85289)
NP_003174 (OMIM: 603639,614328) disintegrin and me ( 824) 5684 862.1 0
XP_011508677 (OMIM: 603639,614328) PREDICTED: disi ( 793) 5454 827.7 0
XP_011508678 (OMIM: 603639,614328) PREDICTED: disi ( 604) 4220 643.2 9.9e-184
XP_016860275 (OMIM: 603639,614328) PREDICTED: disi ( 525) 3686 563.4 9.3e-160
XP_011508679 (OMIM: 603639,614328) PREDICTED: disi ( 525) 3686 563.4 9.3e-160
XP_016860274 (OMIM: 603639,614328) PREDICTED: disi ( 525) 3686 563.4 9.3e-160
NP_001101 (OMIM: 602192,615537,615590) disintegrin ( 748) 727 121.4 1.5e-26
XP_016877350 (OMIM: 602192,615537,615590) PREDICTE ( 674) 716 119.8 4.2e-26
NP_001307499 (OMIM: 602192,615537,615590) disinteg ( 717) 685 115.1 1.1e-24
XP_011527675 (OMIM: 607114) PREDICTED: disintegrin ( 492) 402 72.7 4.4e-12
XP_016865498 (OMIM: 603640) PREDICTED: disintegrin ( 651) 402 72.8 5.5e-12
XP_011532984 (OMIM: 603640) PREDICTED: disintegrin ( 651) 402 72.8 5.5e-12
NP_694882 (OMIM: 607114) disintegrin and metallopr ( 787) 402 72.9 6.3e-12
XP_011527670 (OMIM: 607114) PREDICTED: disintegrin ( 800) 402 72.9 6.3e-12
XP_011527669 (OMIM: 607114) PREDICTED: disintegrin ( 812) 402 72.9 6.4e-12
NP_001269376 (OMIM: 607114) disintegrin and metall ( 812) 402 72.9 6.4e-12
NP_079496 (OMIM: 607114) disintegrin and metallopr ( 813) 402 72.9 6.4e-12
XP_006723703 (OMIM: 607114) PREDICTED: disintegrin ( 823) 402 72.9 6.5e-12
XP_011527668 (OMIM: 607114) PREDICTED: disintegrin ( 825) 402 72.9 6.5e-12
XP_006723702 (OMIM: 607114) PREDICTED: disintegrin ( 825) 402 72.9 6.5e-12
XP_005260900 (OMIM: 607114) PREDICTED: disintegrin ( 826) 402 72.9 6.5e-12
NP_150377 (OMIM: 603640) disintegrin and metallopr ( 918) 402 73.0 7e-12
XP_005266060 (OMIM: 603640) PREDICTED: disintegrin ( 955) 402 73.0 7.2e-12
XP_011527672 (OMIM: 607114) PREDICTED: disintegrin ( 635) 394 71.6 1.2e-11
NP_001248395 (OMIM: 605548) disintegrin and metall ( 633) 391 71.2 1.7e-11
NP_997074 (OMIM: 605548) disintegrin and metallopr ( 772) 391 71.2 1.9e-11
NP_001248394 (OMIM: 605548) disintegrin and metall ( 796) 391 71.3 2e-11
NP_003806 (OMIM: 605548) disintegrin and metallopr ( 814) 391 71.3 2e-11
NP_001248393 (OMIM: 605548) disintegrin and metall ( 824) 391 71.3 2e-11
NP_997078 (OMIM: 605548) disintegrin and metallopr ( 838) 391 71.3 2.1e-11
NP_997077 (OMIM: 605548) disintegrin and metallopr ( 839) 391 71.3 2.1e-11
NP_997079 (OMIM: 605548) disintegrin and metallopr ( 862) 391 71.3 2.1e-11
NP_997080 (OMIM: 605548) disintegrin and metallopr ( 863) 391 71.3 2.1e-11
NP_003803 (OMIM: 603710) disintegrin and metallopr ( 832) 379 69.5 7.1e-11
XP_005246989 (OMIM: 603710) PREDICTED: disintegrin ( 832) 379 69.5 7.1e-11
XP_011510388 (OMIM: 603710) PREDICTED: disintegrin ( 832) 379 69.5 7.1e-11
NP_001124175 (OMIM: 604778) disintegrin and metall ( 820) 367 67.7 2.4e-10
XP_011529863 (OMIM: 604778) PREDICTED: disintegrin ( 820) 367 67.7 2.4e-10
XP_011529862 (OMIM: 604778) PREDICTED: disintegrin ( 820) 367 67.7 2.4e-10
XP_011529861 (OMIM: 604778) PREDICTED: disintegrin ( 820) 367 67.7 2.4e-10
XP_011529859 (OMIM: 604778) PREDICTED: disintegrin ( 820) 367 67.7 2.4e-10
NP_001124176 (OMIM: 604778) disintegrin and metall ( 820) 367 67.7 2.4e-10
NP_001124177 (OMIM: 604778) disintegrin and metall ( 820) 367 67.7 2.4e-10
NP_055084 (OMIM: 604778) disintegrin and metallopr ( 820) 367 67.7 2.4e-10
XP_011529858 (OMIM: 604778) PREDICTED: disintegrin ( 820) 367 67.7 2.4e-10
NP_001265054 (OMIM: 604778) disintegrin and metall ( 820) 367 67.7 2.4e-10
NP_001265055 (OMIM: 604778) disintegrin and metall ( 820) 367 67.7 2.4e-10
NP_001265056 (OMIM: 604778) disintegrin and metall ( 820) 367 67.7 2.4e-10
NP_001275904 (OMIM: 602714) disintegrin and metall ( 735) 362 66.9 3.8e-10
NP_001275903 (OMIM: 602714) disintegrin and metall ( 737) 362 66.9 3.8e-10
>>NP_003174 (OMIM: 603639,614328) disintegrin and metall (824 aa)
initn: 5684 init1: 5684 opt: 5684 Z-score: 4599.9 bits: 862.1 E(85289): 0
Smith-Waterman score: 5684; 100.0% identity (100.0% similar) in 824 aa overlap (1-824:1-824)
10 20 30 40 50 60
pF1KE1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 QTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 HGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 SRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 TCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 KVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 INTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 INTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 SASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKD
730 740 750 760 770 780
790 800 810 820
pF1KE1 PFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC
::::::::::::::::::::::::::::::::::::::::::::
NP_003 PFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC
790 800 810 820
>>XP_011508677 (OMIM: 603639,614328) PREDICTED: disinteg (793 aa)
initn: 5454 init1: 5454 opt: 5454 Z-score: 4414.4 bits: 827.7 E(85289): 0
Smith-Waterman score: 5454; 99.7% identity (100.0% similar) in 793 aa overlap (32-824:1-793)
10 20 30 40 50 60
pF1KE1 RQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQ
..::::::::::::::::::::::::::::
XP_011 MKKLDSLLSDYDILSLSNIQQHSVRKRDLQ
10 20 30
70 80 90 100 110 120
pF1KE1 TSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 EPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 KVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 GEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMA
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 KSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSH
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 GGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 ECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 RVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINAT
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE1 CKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCK
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE1 VCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSI
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE1 NTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDS
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE1 ASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDP
700 710 720 730 740 750
790 800 810 820
pF1KE1 FPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC
:::::::::::::::::::::::::::::::::::::::::::
XP_011 FPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC
760 770 780 790
>>XP_011508678 (OMIM: 603639,614328) PREDICTED: disinteg (604 aa)
initn: 4220 init1: 4220 opt: 4220 Z-score: 3419.5 bits: 643.2 E(85289): 9.9e-184
Smith-Waterman score: 4220; 100.0% identity (100.0% similar) in 604 aa overlap (221-824:1-604)
200 210 220 230 240 250
pF1KE1 NEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNY
::::::::::::::::::::::::::::::
XP_011 MKNTCKLLVVADHRFYRYMGRGEESTTTNY
10 20 30
260 270 280 290 300 310
pF1KE1 LIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKD
40 50 60 70 80 90
320 330 340 350 360 370
pF1KE1 AWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYY
100 110 120 130 140 150
380 390 400 410 420 430
pF1KE1 SPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQG
160 170 180 190 200 210
440 450 460 470 480 490
pF1KE1 GKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECD
220 230 240 250 260 270
500 510 520 530 540 550
pF1KE1 PGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTG
280 290 300 310 320 330
560 570 580 590 600 610
pF1KE1 NSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGR
340 350 360 370 380 390
620 630 640 650 660 670
pF1KE1 CVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLAD
400 410 420 430 440 450
680 690 700 710 720 730
pF1KE1 NIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPF
460 470 480 490 500 510
740 750 760 770 780 790
pF1KE1 PAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAK
520 530 540 550 560 570
800 810 820
pF1KE1 SFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC
::::::::::::::::::::::::::::::::::
XP_011 SFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC
580 590 600
>>XP_016860275 (OMIM: 603639,614328) PREDICTED: disinteg (525 aa)
initn: 3686 init1: 3686 opt: 3686 Z-score: 2989.2 bits: 563.4 E(85289): 9.3e-160
Smith-Waterman score: 3686; 100.0% identity (100.0% similar) in 525 aa overlap (300-824:1-525)
270 280 290 300 310 320
pF1KE1 AGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEA
::::::::::::::::::::::::::::::
XP_016 MAKSYPNEEKDAWDVKMLLEQFSFDIAEEA
10 20 30
330 340 350 360 370 380
pF1KE1 SKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKN
40 50 60 70 80 90
390 400 410 420 430 440
pF1KE1 YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKM
100 110 120 130 140 150
450 460 470 480 490 500
pF1KE1 FSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLK
160 170 180 190 200 210
510 520 530 540 550 560
pF1KE1 EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLD
220 230 240 250 260 270
570 580 590 600 610 620
pF1KE1 LGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKP
280 290 300 310 320 330
630 640 650 660 670 680
pF1KE1 CTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSI
340 350 360 370 380 390
690 700 710 720 730 740
pF1KE1 LVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAP
400 410 420 430 440 450
750 760 770 780 790 800
pF1KE1 AAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASF
460 470 480 490 500 510
810 820
pF1KE1 KLQRQNRVDSKETEC
:::::::::::::::
XP_016 KLQRQNRVDSKETEC
520
>>XP_011508679 (OMIM: 603639,614328) PREDICTED: disinteg (525 aa)
initn: 3686 init1: 3686 opt: 3686 Z-score: 2989.2 bits: 563.4 E(85289): 9.3e-160
Smith-Waterman score: 3686; 100.0% identity (100.0% similar) in 525 aa overlap (300-824:1-525)
270 280 290 300 310 320
pF1KE1 AGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEA
::::::::::::::::::::::::::::::
XP_011 MAKSYPNEEKDAWDVKMLLEQFSFDIAEEA
10 20 30
330 340 350 360 370 380
pF1KE1 SKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKN
40 50 60 70 80 90
390 400 410 420 430 440
pF1KE1 YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKM
100 110 120 130 140 150
450 460 470 480 490 500
pF1KE1 FSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLK
160 170 180 190 200 210
510 520 530 540 550 560
pF1KE1 EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLD
220 230 240 250 260 270
570 580 590 600 610 620
pF1KE1 LGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKP
280 290 300 310 320 330
630 640 650 660 670 680
pF1KE1 CTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSI
340 350 360 370 380 390
690 700 710 720 730 740
pF1KE1 LVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAP
400 410 420 430 440 450
750 760 770 780 790 800
pF1KE1 AAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASF
460 470 480 490 500 510
810 820
pF1KE1 KLQRQNRVDSKETEC
:::::::::::::::
XP_011 KLQRQNRVDSKETEC
520
>>XP_016860274 (OMIM: 603639,614328) PREDICTED: disinteg (525 aa)
initn: 3686 init1: 3686 opt: 3686 Z-score: 2989.2 bits: 563.4 E(85289): 9.3e-160
Smith-Waterman score: 3686; 100.0% identity (100.0% similar) in 525 aa overlap (300-824:1-525)
270 280 290 300 310 320
pF1KE1 AGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEA
::::::::::::::::::::::::::::::
XP_016 MAKSYPNEEKDAWDVKMLLEQFSFDIAEEA
10 20 30
330 340 350 360 370 380
pF1KE1 SKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKN
40 50 60 70 80 90
390 400 410 420 430 440
pF1KE1 YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKM
100 110 120 130 140 150
450 460 470 480 490 500
pF1KE1 FSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLK
160 170 180 190 200 210
510 520 530 540 550 560
pF1KE1 EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLD
220 230 240 250 260 270
570 580 590 600 610 620
pF1KE1 LGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKP
280 290 300 310 320 330
630 640 650 660 670 680
pF1KE1 CTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSI
340 350 360 370 380 390
690 700 710 720 730 740
pF1KE1 LVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAP
400 410 420 430 440 450
750 760 770 780 790 800
pF1KE1 AAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASF
460 470 480 490 500 510
810 820
pF1KE1 KLQRQNRVDSKETEC
:::::::::::::::
XP_016 KLQRQNRVDSKETEC
520
>>NP_001101 (OMIM: 602192,615537,615590) disintegrin and (748 aa)
initn: 627 init1: 240 opt: 727 Z-score: 597.9 bits: 121.4 E(85289): 1.5e-26
Smith-Waterman score: 979; 28.1% identity (56.3% similar) in 778 aa overlap (25-757:16-742)
10 20 30 40 50 60
pF1KE1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
:.: : . :.. . :. :: . . :. ..:
NP_001 MVLLRVLILLLSWAAGMGG-QYGNPLNKYIRHYEGLSYNVDSLHQKHQRAK
10 20 30 40 50
70 80 90 100 110
pF1KE1 QTSTHVETLLT--FSALKRHFKLYLTSSTERFSQNFKVVVVDGKNES-EYTVKWQDFFTG
.. .: . .: : : :::.: . .: ::..::: . .:. .: .. ..::
NP_001 RAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKV---ETSNKVLDYDTS--HIYTG
60 70 80 90 100
120 130 140 150 160 170
pF1KE1 HVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVND-TKDKRMLVYKSEDIKNVS
:. :: : . . : :.: :. . .:: :...: : . ..:. .::.
NP_001 HIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPH
110 120 130 140 150 160
180 190 200 210 220
pF1KE1 RLQSPKVCG----YLKVDNEELLPKGLVDREPPEELVHR----VKRRADPDPMKNTCKLL
. :. . .. . .. : . : :: . .... . ::::.:
NP_001 KYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLY
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 VVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSP
. .:: :..:.: : .. . . .: ::..: : .:... ......::: .
NP_001 IQTDHLFFKYYGTRE--AVIAQISSHVKAIDTIYQTT--DFSGIRNISFMVKRIRINTTA
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 QEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTL
.: : . .:: :. .:: .. .. . :::..:: .::: :.:
NP_001 DEKDPTNPFR-----FPN-----IGVEKFLE---LNSEQNHDDYCLAYVFTDRDFDDGVL
290 300 310 320
350 360 370 380 390 400
pF1KE1 GLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELG
:::.::.: ..: ::.: :. :::. ::.:. ...:::. . : . .. .::.:
NP_001 GLAWVGAP-SGSSGGICEKSKLYSDGKKK-SLNTGIITVQNYGSHVPPKVSHITFAHEVG
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE1 HNFGAEHDPDGLAECAPNEDQG------GKYVMYPIAVSGDHENNKMFSNCSKQSIYKTI
::::. :: .: .::.:.:... :.:.:: :.:::. ::. :: :: ..: ...
NP_001 HNFGSPHD-SG-TECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVL
390 400 410 420 430 440
470 480 490 500 510
pF1KE1 ESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCC-------NSDCTLKEGVQCS
:.: ..:: : .. .:::. :..::::: : .: :: . : :: : :::
NP_001 EKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCS
450 460 470 480 490 500
520 530 540 550 560 570
pF1KE1 DRNSPCCK-NCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGK-C
..::: .: :.. ..::.. .. : . :.: .. :: . : : . :
NP_001 PSQGPCCTAQCAFKSKSEKCRD--DSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVC
510 520 530 540 550 560
580 590 600 610 620
pF1KE1 KDGKCI-PFCEREQQLESCACNETDNS-----CKVCC-RDLS-GRCVPYVDAEQKNLF--
.:.: .::. :: :.: .:.. :.::: . .. . :. ... . :
NP_001 INGQCAGSICEK-YGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSG
570 580 590 600 610 620
630 640 650 660 670
pF1KE1 ----LRKGKPCT--VGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVL
:. :.::. :.::. .: :. :. . .:. :. : .::. ..
NP_001 RTITLQPGSPCNDFRGYCDVFMRC--RLVDAD----GPLARLKKAIFSPELYENIAEWIV
630 640 650 660 670
680 690 700 710 720 730
pF1KE1 VFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLS-SMDSASVRIIKPFPAPQTP
. : ...:. . .: .. . ... : :.. .. : : : :
NP_001 A----HW--WAVLLMGI---------ALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTL
680 690 700 710 720
740 750 760 770 780 790
pF1KE1 GRLQPA-PVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDL
: .: :. :. ..:
NP_001 KRRRPPQPIQQPQRQRPRESYQMGHMRR
730 740
>>XP_016877350 (OMIM: 602192,615537,615590) PREDICTED: d (674 aa)
initn: 690 init1: 240 opt: 716 Z-score: 589.6 bits: 119.8 E(85289): 4.2e-26
Smith-Waterman score: 916; 28.1% identity (56.3% similar) in 718 aa overlap (83-757:1-668)
60 70 80 90 100 110
pF1KE1 HSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNES-EYTVKW
. .: ::..::: . .:. .: ..
XP_016 MKRDTSLFSDEFKV---ETSNKVLDYDTS-
10 20
120 130 140 150 160 170
pF1KE1 QDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVND-TKDKRMLVYKSE
..:::. :: : . . : :.: :. . .:: :...: : . ..:. .
XP_016 -HIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHED
30 40 50 60 70 80
180 190 200 210 220
pF1KE1 DIKNVSRLQSPKVCG----YLKVDNEELLPKGLVDREPPEELVHR----VKRRADPDPMK
::. . :. . .. . .. : . : :: . .... . :
XP_016 DINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEK
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE1 NTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQI
:::.: . .:: :..:.: : .. . . .: ::..: : .:... ......:
XP_016 NTCQLYIQTDHLFFKYYGTRE--AVIAQISSHVKAIDTIYQTT--DFSGIRNISFMVKRI
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE1 RILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQD
:: . .: : . .:: :. .:: .. .. . :::..:: .:
XP_016 RINTTADEKDPTNPF-----RFPN-----IGVEKFLE---LNSEQNHDDYCLAYVFTDRD
210 220 230 240
350 360 370 380 390 400
pF1KE1 FDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLV
:: :.::::.::.: ..: ::.: :. :::. ::.:. ...:::. . : . ..
XP_016 FDDGVLGLAWVGAPSGSS-GGICEKSKLYSDGKKK-SLNTGIITVQNYGSHVPPKVSHIT
250 260 270 280 290 300
410 420 430 440 450
pF1KE1 TTHELGHNFGAEHDPDGLAECAPNEDQG------GKYVMYPIAVSGDHENNKMFSNCSKQ
.::.:::::. :: .: .::.:.:... :.:.:: :.:::. ::. :: :: .
XP_016 FAHEVGHNFGSPHD-SG-TECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIR
310 320 330 340 350 360
460 470 480 490 500
pF1KE1 SIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCC-------NSDCTLK
.: ...:.: ..:: : .. .:::. :..::::: : .: :: . : ::
XP_016 NISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLK
370 380 390 400 410 420
510 520 530 540 550 560
pF1KE1 EGVQCSDRNSPCCK-NCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCL
: ::: ..::: .: :.. ..::.. .. : . :.: .. :: . : :
XP_016 PGKQCSPSQGPCCTAQCAFKSKSEKCRD--DSDCAREGICNGFTALCPASDPKPNFTDCN
430 440 450 460 470 480
570 580 590 600 610
pF1KE1 DLGK-CKDGKCI-PFCEREQQLESCACNETDNS-----CKVCC-RDLS-GRCVPYVDAEQ
. : .:.: .::. :: :.: .:.. :.::: . .. . :. ...
XP_016 RHTQVCINGQCAGSICEK-YGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQW
490 500 510 520 530 540
620 630 640 650 660 670
pF1KE1 KNLF------LRKGKPCT--VGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADN
. : :. :.::. :.::. .: :. :. . .:. :. : .:
XP_016 SRHFSGRTITLQPGSPCNDFRGYCDVFMRC--RLVDAD----GPLARLKKAIFSPELYEN
550 560 570 580 590
680 690 700 710 720 730
pF1KE1 IVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLS-SMDSASVRIIKPF
:. ... : ...:. . .: .. . ... : :.. .. :
XP_016 IAEWIVA----HW--WAVLLMGI---------ALIMLMAGFIKICSVHTPSSNPKLPPPK
600 610 620 630 640
740 750 760 770 780
pF1KE1 PAPQTPGRLQPA-PVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAA
: : : : .: :. :. ..:
XP_016 PLPGTLKRRRPPQPIQQPQRQRPRESYQMGHMRR
650 660 670
>>NP_001307499 (OMIM: 602192,615537,615590) disintegrin (717 aa)
initn: 739 init1: 240 opt: 685 Z-score: 564.2 bits: 115.1 E(85289): 1.1e-24
Smith-Waterman score: 882; 27.6% identity (54.4% similar) in 778 aa overlap (25-757:16-711)
10 20 30 40 50 60
pF1KE1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
:.: : . :.. . :. :: . . :. ..:
NP_001 MVLLRVLILLLSWAAGMGG-QYGNPLNKYIRHYEGLSYNVDSLHQKHQRAK
10 20 30 40 50
70 80 90 100 110
pF1KE1 QTSTHVETLLT--FSALKRHFKLYLTSSTERFSQNFKVVVVDGKNES-EYTVKWQDFFTG
.. .: . .: : : :::.: . .: ::..::: . .:. .: .. ..::
NP_001 RAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKV---ETSNKVLDYDTS--HIYTG
60 70 80 90 100
120 130 140 150 160 170
pF1KE1 HVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVND-TKDKRMLVYKSEDIKNVS
:. :: : . . : :.: :. . .:: :...: : . ..:. .::.
NP_001 HIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPH
110 120 130 140 150 160
180 190 200 210 220
pF1KE1 RLQSPKVCG----YLKVDNEELLPKGLVDREPPEELVHR----VKRRADPDPMKNTCKLL
. :. . .. . .. : . : :: . .... . ::::.:
NP_001 KYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLY
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 VVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSP
. .:: :..:.: : .: .. ::. :. :.:
NP_001 IQTDHLFFKYYGTRE---------AVIAQI-----NTTADE----------------KDP
230 240 250
290 300 310 320 330 340
pF1KE1 QEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTL
..: . .:: :. .:: .. .. . :::..:: .::: :.:
NP_001 --TNPFR--------FPN-----IGVEKFLE---LNSEQNHDDYCLAYVFTDRDFDDGVL
260 270 280 290
350 360 370 380 390 400
pF1KE1 GLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELG
:::.::.: ..: ::.: :. :::. ::.:. ...:::. . : . .. .::.:
NP_001 GLAWVGAP-SGSSGGICEKSKLYSDGKKK-SLNTGIITVQNYGSHVPPKVSHITFAHEVG
300 310 320 330 340 350
410 420 430 440 450 460
pF1KE1 HNFGAEHDPDGLAECAPNEDQG------GKYVMYPIAVSGDHENNKMFSNCSKQSIYKTI
::::. :: .: .::.:.:... :.:.:: :.:::. ::. :: :: ..: ...
NP_001 HNFGSPHD-SG-TECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVL
360 370 380 390 400 410
470 480 490 500 510
pF1KE1 ESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCC-------NSDCTLKEGVQCS
:.: ..:: : .. .:::. :..::::: : .: :: . : :: : :::
NP_001 EKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCS
420 430 440 450 460 470
520 530 540 550 560 570
pF1KE1 DRNSPCCK-NCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGK-C
..::: .: :.. ..::.. .. : . :.: .. :: . : : . :
NP_001 PSQGPCCTAQCAFKSKSEKCRD--DSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVC
480 490 500 510 520 530
580 590 600 610 620
pF1KE1 KDGKCI-PFCEREQQLESCACNETDNS-----CKVCC-RDLS-GRCVPYVDAEQKNLF--
.:.: .::. :: :.: .:.. :.::: . .. . :. ... . :
NP_001 INGQCAGSICEK-YGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSG
540 550 560 570 580 590
630 640 650 660 670
pF1KE1 ----LRKGKPCT--VGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVL
:. :.::. :.::. .: :. :. . .:. :. : .::. ..
NP_001 RTITLQPGSPCNDFRGYCDVFMRC--RLVDAD----GPLARLKKAIFSPELYENIAEWIV
600 610 620 630 640
680 690 700 710 720 730
pF1KE1 VFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLS-SMDSASVRIIKPFPAPQTP
. : ...:. . .: .. . ... : :.. .. : : : :
NP_001 A----HW--WAVLLMGI---------ALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTL
650 660 670 680
740 750 760 770 780 790
pF1KE1 GRLQPA-PVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDL
: .: :. :. ..:
NP_001 KRRRPPQPIQQPQRQRPRESYQMGHMRR
690 700 710
>>XP_011527675 (OMIM: 607114) PREDICTED: disintegrin and (492 aa)
initn: 176 init1: 97 opt: 402 Z-score: 337.8 bits: 72.7 E(85289): 4.4e-12
Smith-Waterman score: 413; 31.6% identity (54.3% similar) in 247 aa overlap (405-629:24-262)
380 390 400 410 420 430
pF1KE1 KKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYV
::.::..: ::::: :. ..: :
XP_011 MCRAESSGGDHSELPIGAAATMAHEIGHSLGLSHDPDGC--CVEAAAESGGCV
10 20 30 40 50
440 450 460 470 480
pF1KE1 MYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNK-------VCGNSRVDEGE
: :..: : ..:: ::.... ... . :... . .:::. :. ::
XP_011 M--AAATG-HPFPRVFSACSRRQLRAFFRKGGGACLSNAPDPGLPVPPALCGNGFVEAGE
60 70 80 90 100
490 500 510 520 530 540
pF1KE1 ECDPGIMYLNNDTCC-NSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVS
::: : : :: .:.:. :.::. .. :: : .. : :..:.. :
XP_011 ECDCGPGQECRDLCCFAHNCSLRPGAQCA--HGDCCVRCLLKPAGALCRQAMG-DCDLPE
110 120 130 140 150 160
550 560 570 580 590
pF1KE1 YCTGNSSECPPPGNAEDDTVCL-DLGKCKDGKCIPFCEREQQL---------ESC--ACN
.:::.::.::: : . : : : :: : . .. ::: :.: . :
XP_011 FCTGTSSHCPPDVYLLDGSPCARGSGYCWDGACPTLEQQCQQLWGPGSHPAPEACFQVVN
170 180 190 200 210 220
600 610 620 630 640 650
pF1KE1 ETDNSCKVCCRDLSGRCVPYV--DAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERF
. .. : .: :. .: . :: .: . :::
XP_011 SAGDAHGNCGQDSEGHFLPCAGRDALCGKLQCQGGKPSLLAPHMVPVDSTVHLDGQEVTC
230 240 250 260 270 280
660 670 680 690 700 710
pF1KE1 WDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSN
XP_011 RGALALPSAQLDLLGLGLVEPGTQCGPRMVCQSRRCRKNAFQELQRCLTACHSHGVCNSN
290 300 310 320 330 340
824 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:35:24 2016 done: Tue Nov 8 16:35:25 2016
Total Scan time: 7.790 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]