Result of FASTA (omim) for
pFN21AE1888
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1888, 416 aa
1>>>pF1KE1888 416 - 416 aa - 416 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2865+/-0.000351; mu= 14.0764+/- 0.022
mean_var=120.9100+/-24.031, 0's: 0 Z-trim(117.5): 42 B-trim: 37 in 1/53
Lambda= 0.116639
statistics sampled from 29447 (29489) to 29447 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.346), width: 16
Scan time: 9.060
The best scores are: opt bits E(85289)
NP_001177874 (OMIM: 601711) TNF receptor-associate ( 416) 2817 485.0 1.4e-136
NP_005649 (OMIM: 601711) TNF receptor-associated f ( 416) 2817 485.0 1.4e-136
NP_001177876 (OMIM: 601711) TNF receptor-associate ( 294) 1936 336.7 4.7e-92
XP_011517277 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 879 159.0 2.4e-38
XP_011517278 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 879 159.0 2.4e-38
XP_011517279 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 879 159.0 2.4e-38
NP_066961 (OMIM: 601895) TNF receptor-associated f ( 501) 879 159.0 2.4e-38
XP_016870584 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 879 159.0 2.4e-38
XP_011517276 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 879 159.0 2.4e-38
XP_011517280 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 879 159.0 2.4e-38
XP_016870583 (OMIM: 601895) PREDICTED: TNF recepto ( 533) 879 159.0 2.5e-38
XP_011517275 (OMIM: 601895) PREDICTED: TNF recepto ( 556) 879 159.0 2.6e-38
NP_663777 (OMIM: 601896,614849) TNF receptor-assoc ( 568) 788 143.7 1.1e-33
XP_016877106 (OMIM: 601896,614849) PREDICTED: TNF ( 568) 788 143.7 1.1e-33
XP_016877107 (OMIM: 601896,614849) PREDICTED: TNF ( 568) 788 143.7 1.1e-33
NP_003291 (OMIM: 601896,614849) TNF receptor-assoc ( 568) 788 143.7 1.1e-33
NP_663778 (OMIM: 601896,614849) TNF receptor-assoc ( 543) 725 133.1 1.6e-30
XP_016877108 (OMIM: 601896,614849) PREDICTED: TNF ( 543) 725 133.1 1.6e-30
NP_001029082 (OMIM: 602356) TNF receptor-associate ( 557) 722 132.6 2.4e-30
XP_016857710 (OMIM: 602356) PREDICTED: TNF recepto ( 557) 722 132.6 2.4e-30
NP_004610 (OMIM: 602356) TNF receptor-associated f ( 557) 722 132.6 2.4e-30
NP_665702 (OMIM: 602356) TNF receptor-associated f ( 557) 722 132.6 2.4e-30
NP_001306136 (OMIM: 602356) TNF receptor-associate ( 568) 722 132.6 2.4e-30
XP_011508261 (OMIM: 602356) PREDICTED: TNF recepto ( 568) 722 132.6 2.4e-30
XP_011508262 (OMIM: 602356) PREDICTED: TNF recepto ( 568) 722 132.6 2.4e-30
XP_011508259 (OMIM: 602356) PREDICTED: TNF recepto ( 631) 722 132.7 2.6e-30
XP_011535418 (OMIM: 601896,614849) PREDICTED: TNF ( 516) 720 132.3 2.8e-30
XP_011535420 (OMIM: 601896,614849) PREDICTED: TNF ( 485) 671 124.0 8.2e-28
NP_001186356 (OMIM: 601896,614849) TNF receptor-as ( 485) 671 124.0 8.2e-28
XP_011535419 (OMIM: 601896,614849) PREDICTED: TNF ( 512) 671 124.0 8.5e-28
XP_011523810 (OMIM: 602464) PREDICTED: TNF recepto ( 352) 374 73.9 7.1e-13
XP_011523809 (OMIM: 602464) PREDICTED: TNF recepto ( 352) 374 73.9 7.1e-13
XP_011523808 (OMIM: 602464) PREDICTED: TNF recepto ( 454) 374 74.0 8.6e-13
XP_011523807 (OMIM: 602464) PREDICTED: TNF recepto ( 461) 374 74.0 8.7e-13
NP_004286 (OMIM: 602464) TNF receptor-associated f ( 470) 374 74.0 8.8e-13
XP_011523806 (OMIM: 602464) PREDICTED: TNF recepto ( 477) 374 74.0 8.9e-13
NP_665802 (OMIM: 602355) TNF receptor-associated f ( 522) 373 73.9 1.1e-12
NP_004611 (OMIM: 602355) TNF receptor-associated f ( 522) 373 73.9 1.1e-12
>>NP_001177874 (OMIM: 601711) TNF receptor-associated fa (416 aa)
initn: 2817 init1: 2817 opt: 2817 Z-score: 2572.9 bits: 485.0 E(85289): 1.4e-136
Smith-Waterman score: 2817; 100.0% identity (100.0% similar) in 416 aa overlap (1-416:1-416)
10 20 30 40 50 60
pF1KE1 MASSSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGEDQICPKCRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGEDQICPKCRGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DLQSISPGSRLRTQEKAHPEVAEAGIGCPFAGVGCSFKGSPQSVQEHEVTSQTSHLNLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQSISPGSRLRTQEKAHPEVAEAGIGCPFAGVGCSFKGSPQSVQEHEVTSQTSHLNLLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQEELALQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQEELALQH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLEQRVVELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLEQRVVELQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAID
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 AFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETST
370 380 390 400 410
>>NP_005649 (OMIM: 601711) TNF receptor-associated facto (416 aa)
initn: 2817 init1: 2817 opt: 2817 Z-score: 2572.9 bits: 485.0 E(85289): 1.4e-136
Smith-Waterman score: 2817; 100.0% identity (100.0% similar) in 416 aa overlap (1-416:1-416)
10 20 30 40 50 60
pF1KE1 MASSSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGEDQICPKCRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MASSSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGEDQICPKCRGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DLQSISPGSRLRTQEKAHPEVAEAGIGCPFAGVGCSFKGSPQSVQEHEVTSQTSHLNLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLQSISPGSRLRTQEKAHPEVAEAGIGCPFAGVGCSFKGSPQSVQEHEVTSQTSHLNLLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQEELALQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQEELALQH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLEQRVVELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLEQRVVELQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 YGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAID
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 AFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETST
370 380 390 400 410
>>NP_001177876 (OMIM: 601711) TNF receptor-associated fa (294 aa)
initn: 1936 init1: 1936 opt: 1936 Z-score: 1773.6 bits: 336.7 E(85289): 4.7e-92
Smith-Waterman score: 1936; 100.0% identity (100.0% similar) in 294 aa overlap (123-416:1-294)
100 110 120 130 140 150
pF1KE1 VGCSFKGSPQSVQEHEVTSQTSHLNLLLGFMKQWKARLGCGLESGPMALEQNLSDLQLQA
::::::::::::::::::::::::::::::
NP_001 MKQWKARLGCGLESGPMALEQNLSDLQLQA
10 20 30
160 170 180 190 200 210
pF1KE1 AVEVAGDLEVDCYRAPCSESQEELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVEVAGDLEVDCYRAPCSESQEELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEASH
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE1 LALATSIHQSQLDRERILSLEQRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALATSIHQSQLDRERILSLEQRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWK
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE1 ITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGE
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE1 YDALLPWPFRNKVTFMLLDQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDALLPWPFRNKVTFMLLDQNNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSK
220 230 240 250 260 270
400 410
pF1KE1 LQSPKHAYVKDDTMFLKCIVETST
::::::::::::::::::::::::
NP_001 LQSPKHAYVKDDTMFLKCIVETST
280 290
>>XP_011517277 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 932 init1: 809 opt: 879 Z-score: 809.3 bits: 159.0 E(85289): 2.4e-38
Smith-Waterman score: 908; 42.3% identity (65.1% similar) in 392 aa overlap (34-415:159-499)
10 20 30 40 50
pF1KE1 SSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGED-----QICPKCR
:.: : : . : : : ..:::
XP_011 CPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHC--RAPCCGADVKAHHEVCPKF-
130 140 150 160 170 180
60 70 80 90 100 110
pF1KE1 GEDLQSISPGSRLRTQEKAHPEVAEAG---IGCPFAGVGC--SFKGSPQSVQEHEVTSQT
: . :.. .:: . .: : . : : ..:: . .: : :::::
XP_011 --PLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQ--QEHEVQWLR
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE1 SHLNLLLGFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQ
:: .::. . ::. :. :.: : .:. : : : ::
XP_011 EHLAMLLSSV----------LEAKPL-----LGD-QSHAGSE----LLQRC------ES-
250 260 270
180 190 200 210 220 230
pF1KE1 EELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLE
:: : .::::: :::.::: .. . .: .::...: .:
XP_011 ----------------LEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALS
280 290 300 310
240 250 260 270 280 290
pF1KE1 QRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFS
..: .:..... :: :.. :::.. :: ...::.:.:::.. .:. .:.. :: ..::
XP_011 SKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFS
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 PAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQN
:::::..::::.:::.::::::::. ::::::.:.:.: :::: ::: .:::.::::::
XP_011 PAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE1 NREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVE
::::.:::::::..:.::::: .. :.::::::: :.::... :..::.::..:.: ::.
XP_011 NREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA-KNSYVRDDAIFIKAIVD
440 450 460 470 480 490
pF1KE1 TST
.
XP_011 LTGL
500
>>XP_011517278 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 932 init1: 809 opt: 879 Z-score: 809.3 bits: 159.0 E(85289): 2.4e-38
Smith-Waterman score: 908; 42.3% identity (65.1% similar) in 392 aa overlap (34-415:159-499)
10 20 30 40 50
pF1KE1 SSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGED-----QICPKCR
:.: : : . : : : ..:::
XP_011 CPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHC--RAPCCGADVKAHHEVCPKF-
130 140 150 160 170 180
60 70 80 90 100 110
pF1KE1 GEDLQSISPGSRLRTQEKAHPEVAEAG---IGCPFAGVGC--SFKGSPQSVQEHEVTSQT
: . :.. .:: . .: : . : : ..:: . .: : :::::
XP_011 --PLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQ--QEHEVQWLR
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE1 SHLNLLLGFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQ
:: .::. . ::. :. :.: : .:. : : : ::
XP_011 EHLAMLLSSV----------LEAKPL-----LGD-QSHAGSE----LLQRC------ES-
250 260 270
180 190 200 210 220 230
pF1KE1 EELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLE
:: : .::::: :::.::: .. . .: .::...: .:
XP_011 ----------------LEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALS
280 290 300 310
240 250 260 270 280 290
pF1KE1 QRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFS
..: .:..... :: :.. :::.. :: ...::.:.:::.. .:. .:.. :: ..::
XP_011 SKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFS
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 PAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQN
:::::..::::.:::.::::::::. ::::::.:.:.: :::: ::: .:::.::::::
XP_011 PAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE1 NREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVE
::::.:::::::..:.::::: .. :.::::::: :.::... :..::.::..:.: ::.
XP_011 NREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA-KNSYVRDDAIFIKAIVD
440 450 460 470 480 490
pF1KE1 TST
.
XP_011 LTGL
500
>>XP_011517279 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 932 init1: 809 opt: 879 Z-score: 809.3 bits: 159.0 E(85289): 2.4e-38
Smith-Waterman score: 908; 42.3% identity (65.1% similar) in 392 aa overlap (34-415:159-499)
10 20 30 40 50
pF1KE1 SSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGED-----QICPKCR
:.: : : . : : : ..:::
XP_011 CPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHC--RAPCCGADVKAHHEVCPKF-
130 140 150 160 170 180
60 70 80 90 100 110
pF1KE1 GEDLQSISPGSRLRTQEKAHPEVAEAG---IGCPFAGVGC--SFKGSPQSVQEHEVTSQT
: . :.. .:: . .: : . : : ..:: . .: : :::::
XP_011 --PLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQ--QEHEVQWLR
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE1 SHLNLLLGFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQ
:: .::. . ::. :. :.: : .:. : : : ::
XP_011 EHLAMLLSSV----------LEAKPL-----LGD-QSHAGSE----LLQRC------ES-
250 260 270
180 190 200 210 220 230
pF1KE1 EELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLE
:: : .::::: :::.::: .. . .: .::...: .:
XP_011 ----------------LEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALS
280 290 300 310
240 250 260 270 280 290
pF1KE1 QRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFS
..: .:..... :: :.. :::.. :: ...::.:.:::.. .:. .:.. :: ..::
XP_011 SKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFS
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 PAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQN
:::::..::::.:::.::::::::. ::::::.:.:.: :::: ::: .:::.::::::
XP_011 PAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE1 NREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVE
::::.:::::::..:.::::: .. :.::::::: :.::... :..::.::..:.: ::.
XP_011 NREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA-KNSYVRDDAIFIKAIVD
440 450 460 470 480 490
pF1KE1 TST
.
XP_011 LTGL
500
>>NP_066961 (OMIM: 601895) TNF receptor-associated facto (501 aa)
initn: 932 init1: 809 opt: 879 Z-score: 809.3 bits: 159.0 E(85289): 2.4e-38
Smith-Waterman score: 908; 42.3% identity (65.1% similar) in 392 aa overlap (34-415:159-499)
10 20 30 40 50
pF1KE1 SSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGED-----QICPKCR
:.: : : . : : : ..:::
NP_066 CPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHC--RAPCCGADVKAHHEVCPKF-
130 140 150 160 170 180
60 70 80 90 100 110
pF1KE1 GEDLQSISPGSRLRTQEKAHPEVAEAG---IGCPFAGVGC--SFKGSPQSVQEHEVTSQT
: . :.. .:: . .: : . : : ..:: . .: : :::::
NP_066 --PLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQ--QEHEVQWLR
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE1 SHLNLLLGFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQ
:: .::. . ::. :. :.: : .:. : : : ::
NP_066 EHLAMLLSSV----------LEAKPL-----LGD-QSHAGSE----LLQRC------ES-
250 260 270
180 190 200 210 220 230
pF1KE1 EELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLE
:: : .::::: :::.::: .. . .: .::...: .:
NP_066 ----------------LEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALS
280 290 300 310
240 250 260 270 280 290
pF1KE1 QRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFS
..: .:..... :: :.. :::.. :: ...::.:.:::.. .:. .:.. :: ..::
NP_066 SKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFS
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 PAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQN
:::::..::::.:::.::::::::. ::::::.:.:.: :::: ::: .:::.::::::
NP_066 PAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE1 NREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVE
::::.:::::::..:.::::: .. :.::::::: :.::... :..::.::..:.: ::.
NP_066 NREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA-KNSYVRDDAIFIKAIVD
440 450 460 470 480 490
pF1KE1 TST
.
NP_066 LTGL
500
>>XP_016870584 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 932 init1: 809 opt: 879 Z-score: 809.3 bits: 159.0 E(85289): 2.4e-38
Smith-Waterman score: 908; 42.3% identity (65.1% similar) in 392 aa overlap (34-415:159-499)
10 20 30 40 50
pF1KE1 SSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGED-----QICPKCR
:.: : : . : : : ..:::
XP_016 CPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHC--RAPCCGADVKAHHEVCPKF-
130 140 150 160 170 180
60 70 80 90 100 110
pF1KE1 GEDLQSISPGSRLRTQEKAHPEVAEAG---IGCPFAGVGC--SFKGSPQSVQEHEVTSQT
: . :.. .:: . .: : . : : ..:: . .: : :::::
XP_016 --PLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQ--QEHEVQWLR
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE1 SHLNLLLGFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQ
:: .::. . ::. :. :.: : .:. : : : ::
XP_016 EHLAMLLSSV----------LEAKPL-----LGD-QSHAGSE----LLQRC------ES-
250 260 270
180 190 200 210 220 230
pF1KE1 EELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLE
:: : .::::: :::.::: .. . .: .::...: .:
XP_016 ----------------LEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALS
280 290 300 310
240 250 260 270 280 290
pF1KE1 QRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFS
..: .:..... :: :.. :::.. :: ...::.:.:::.. .:. .:.. :: ..::
XP_016 SKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFS
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 PAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQN
:::::..::::.:::.::::::::. ::::::.:.:.: :::: ::: .:::.::::::
XP_016 PAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE1 NREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVE
::::.:::::::..:.::::: .. :.::::::: :.::... :..::.::..:.: ::.
XP_016 NREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA-KNSYVRDDAIFIKAIVD
440 450 460 470 480 490
pF1KE1 TST
.
XP_016 LTGL
500
>>XP_011517276 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 932 init1: 809 opt: 879 Z-score: 809.3 bits: 159.0 E(85289): 2.4e-38
Smith-Waterman score: 908; 42.3% identity (65.1% similar) in 392 aa overlap (34-415:159-499)
10 20 30 40 50
pF1KE1 SSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGED-----QICPKCR
:.: : : . : : : ..:::
XP_011 CPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHC--RAPCCGADVKAHHEVCPKF-
130 140 150 160 170 180
60 70 80 90 100 110
pF1KE1 GEDLQSISPGSRLRTQEKAHPEVAEAG---IGCPFAGVGC--SFKGSPQSVQEHEVTSQT
: . :.. .:: . .: : . : : ..:: . .: : :::::
XP_011 --PLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQ--QEHEVQWLR
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE1 SHLNLLLGFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQ
:: .::. . ::. :. :.: : .:. : : : ::
XP_011 EHLAMLLSSV----------LEAKPL-----LGD-QSHAGSE----LLQRC------ES-
250 260 270
180 190 200 210 220 230
pF1KE1 EELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLE
:: : .::::: :::.::: .. . .: .::...: .:
XP_011 ----------------LEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALS
280 290 300 310
240 250 260 270 280 290
pF1KE1 QRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFS
..: .:..... :: :.. :::.. :: ...::.:.:::.. .:. .:.. :: ..::
XP_011 SKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFS
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 PAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQN
:::::..::::.:::.::::::::. ::::::.:.:.: :::: ::: .:::.::::::
XP_011 PAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE1 NREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVE
::::.:::::::..:.::::: .. :.::::::: :.::... :..::.::..:.: ::.
XP_011 NREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA-KNSYVRDDAIFIKAIVD
440 450 460 470 480 490
pF1KE1 TST
.
XP_011 LTGL
500
>>XP_011517280 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 932 init1: 809 opt: 879 Z-score: 809.3 bits: 159.0 E(85289): 2.4e-38
Smith-Waterman score: 908; 42.3% identity (65.1% similar) in 392 aa overlap (34-415:159-499)
10 20 30 40 50
pF1KE1 SSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGED-----QICPKCR
:.: : : . : : : ..:::
XP_011 CPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHC--RAPCCGADVKAHHEVCPKF-
130 140 150 160 170 180
60 70 80 90 100 110
pF1KE1 GEDLQSISPGSRLRTQEKAHPEVAEAG---IGCPFAGVGC--SFKGSPQSVQEHEVTSQT
: . :.. .:: . .: : . : : ..:: . .: : :::::
XP_011 --PLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQ--QEHEVQWLR
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE1 SHLNLLLGFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQ
:: .::. . ::. :. :.: : .:. : : : ::
XP_011 EHLAMLLSSV----------LEAKPL-----LGD-QSHAGSE----LLQRC------ES-
250 260 270
180 190 200 210 220 230
pF1KE1 EELALQHFMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLE
:: : .::::: :::.::: .. . .: .::...: .:
XP_011 ----------------LEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALS
280 290 300 310
240 250 260 270 280 290
pF1KE1 QRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFS
..: .:..... :: :.. :::.. :: ...::.:.:::.. .:. .:.. :: ..::
XP_011 SKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFS
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 PAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQN
:::::..::::.:::.::::::::. ::::::.:.:.: :::: ::: .:::.::::::
XP_011 PAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN
380 390 400 410 420 430
360 370 380 390 400 410
pF1KE1 NREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVE
::::.:::::::..:.::::: .. :.::::::: :.::... :..::.::..:.: ::.
XP_011 NREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA-KNSYVRDDAIFIKAIVD
440 450 460 470 480 490
pF1KE1 TST
.
XP_011 LTGL
500
416 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:31:57 2016 done: Sun Nov 6 21:31:58 2016
Total Scan time: 9.060 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]