FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1884, 410 aa
  1>>>pF1KE1884 410 - 410 aa - 410 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2413+/-0.000354; mu= 10.2514+/- 0.022
 mean_var=152.3233+/-30.456, 0's: 0 Z-trim(118.6): 4  B-trim: 44 in 1/57
 Lambda= 0.103918
 statistics sampled from 31712 (31716) to 31712 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.372), width:  16
 Scan time:  9.400

The best scores are:                                      opt bits E(85289)
NP_003202 (OMIM: 601423) G/T mismatch-specific thy ( 410) 2774 427.4 3.1e-119
XP_011537016 (OMIM: 601423) PREDICTED: G/T mismatc ( 267) 1846 288.2 1.7e-77
XP_005269182 (OMIM: 601423) PREDICTED: G/T mismatc ( 206) 1216 193.6 3.8e-49
XP_011537017 (OMIM: 601423) PREDICTED: G/T mismatc ( 206) 1216 193.6 3.8e-49


>>NP_003202 (OMIM: 601423) G/T mismatch-specific thymine  (410 aa)
 initn: 2774 init1: 2774 opt: 2774  Z-score: 2261.7  bits: 427.4 E(85289): 3.1e-119
Smith-Waterman score: 2774; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:1-410)

               10        20        30        40        50        60
pF1KE1 MEAENAGSYSLQQAQAFYTFPFQQLMAEAPNMAVVNEQQMPEEVPAPAPAQEPVQEAPKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEAENAGSYSLQQAQAFYTFPFQQLMAEAPNMAVVNEQQMPEEVPAPAPAQEPVQEAPKG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 RKRKPRTTEPKQPVEPKKPVESKKSGKSAKSKEKQEKITDTFKVKRKVDRFNGVSEAELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RKRKPRTTEPKQPVEPKKPVESKKSGKSAKSKEKQEKITDTFKVKRKVDRFNGVSEAELL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 TKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQLNHMDDHT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 LPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFSK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 EVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQLK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 GIERNMDVQEVQYTFDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCSSEPCGFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GIERNMDVQEVQYTFDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCSSEPCGFSS
              310       320       330       340       350       360

              370       380       390       400       410
pF1KE1 NGLIESVELRGESAFSGIPNGQWMTQSFTDQIPSFSNHCGTQEQEEESHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NGLIESVELRGESAFSGIPNGQWMTQSFTDQIPSFSNHCGTQEQEEESHA
              370       380       390       400       410

>>XP_011537016 (OMIM: 601423) PREDICTED: G/T mismatch-sp  (267 aa)
 initn: 1846 init1: 1846 opt: 1846  Z-score: 1512.3  bits: 288.2 E(85289): 1.7e-77
Smith-Waterman score: 1846; 100.0% identity (100.0% similar) in 267 aa overlap (144-410:1-267)

           120       130       140       150       160       170   
pF1KE1 VSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFWKCLFMSGLSEVQL
                                     ::::::::::::::::::::::::::::::
XP_011                               MAAYKGHHYPGPGNHFWKCLFMSGLSEVQL
                                             10        20        30

           180       190       200       210       220       230   
pF1KE1 NHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHMDDHTLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKC
               40        50        60        70        80        90

           240       250       260       270       280       290   
pF1KE1 IYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYEIFSKEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLK
              100       110       120       130       140       150

           300       310       320       330       340       350   
pF1KE1 DLRDQLKGIERNMDVQEVQYTFDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLRDQLKGIERNMDVQEVQYTFDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCSS
              160       170       180       190       200       210

           360       370       380       390       400       410
pF1KE1 EPCGFSSNGLIESVELRGESAFSGIPNGQWMTQSFTDQIPSFSNHCGTQEQEEESHA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPCGFSSNGLIESVELRGESAFSGIPNGQWMTQSFTDQIPSFSNHCGTQEQEEESHA
              220       230       240       250       260       

>>XP_005269182 (OMIM: 601423) PREDICTED: G/T mismatch-sp  (206 aa)
 initn: 1215 init1: 1215 opt: 1216  Z-score: 1003.4  bits: 193.6 E(85289): 3.8e-49
Smith-Waterman score: 1216; 90.5% identity (93.0% similar) in 201 aa overlap (210-410:6-206)

     180       190       200       210       220       230         
pF1KE1 TLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFS
                                     .:. .:        :: :.  .  ::::::
XP_005                          MITLYQGSMVLDLPTWWKGPRPAAKISPGIYEIFS
                                        10        20        30     

     240       250       260       270       280       290         
pF1KE1 KEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL
          40        50        60        70        80        90     

     300       310       320       330       340       350         
pF1KE1 KGIERNMDVQEVQYTFDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCSSEPCGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGIERNMDVQEVQYTFDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCSSEPCGFS
         100       110       120       130       140       150     

     360       370       380       390       400       410
pF1KE1 SNGLIESVELRGESAFSGIPNGQWMTQSFTDQIPSFSNHCGTQEQEEESHA
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNGLIESVELRGESAFSGIPNGQWMTQSFTDQIPSFSNHCGTQEQEEESHA
         160       170       180       190       200      

>>XP_011537017 (OMIM: 601423) PREDICTED: G/T mismatch-sp  (206 aa)
 initn: 1215 init1: 1215 opt: 1216  Z-score: 1003.4  bits: 193.6 E(85289): 3.8e-49
Smith-Waterman score: 1216; 90.5% identity (93.0% similar) in 201 aa overlap (210-410:6-206)

     180       190       200       210       220       230         
pF1KE1 TLPGKYGIGFTNMVERTTPGSKDLSSKEFREGGRILVQKLQKYQPRIAVFNGKCIYEIFS
                                     .:. .:        :: :.  .  ::::::
XP_011                          MITLYQGSMVLDLPTWWKGPRPAAKISPGIYEIFS
                                        10        20        30     

     240       250       260       270       280       290         
pF1KE1 KEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVFGVKVKNLEFGLQPHKIPDTETLCYVMPSSSARCAQFPRAQDKVHYYIKLKDLRDQL
          40        50        60        70        80        90     

     300       310       320       330       340       350         
pF1KE1 KGIERNMDVQEVQYTFDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCSSEPCGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGIERNMDVQEVQYTFDLQLAQEDAKKMAVKEEKYDPGYEAAYGGAYGENPCSSEPCGFS
         100       110       120       130       140       150     

     360       370       380       390       400       410
pF1KE1 SNGLIESVELRGESAFSGIPNGQWMTQSFTDQIPSFSNHCGTQEQEEESHA
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNGLIESVELRGESAFSGIPNGQWMTQSFTDQIPSFSNHCGTQEQEEESHA
         160       170       180       190       200      




410 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 14:43:13 2016 done: Sun Nov  6 14:43:14 2016
 Total Scan time:  9.400 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]