Result of FASTA (omim) for
pFN21AE1882
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1882, 401 aa
1>>>pF1KE1882 401 - 401 aa - 401 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3361+/-0.000382; mu= 13.2031+/- 0.024
mean_var=114.2943+/-22.778, 0's: 0 Z-trim(115.0): 40 B-trim: 47 in 1/57
Lambda= 0.119967
statistics sampled from 25099 (25136) to 25099 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.295), width: 16
Scan time: 9.290
The best scores are: opt bits E(85289)
NP_001248342 (OMIM: 607376) dynactin subunit 2 iso ( 401) 2522 447.5 2.6e-125
NP_001248341 (OMIM: 607376) dynactin subunit 2 iso ( 403) 2508 445.1 1.4e-124
NP_006391 (OMIM: 607376) dynactin subunit 2 isofor ( 406) 2502 444.1 2.9e-124
XP_011536063 (OMIM: 607376) PREDICTED: dynactin su ( 314) 1947 347.9 2e-95
>>NP_001248342 (OMIM: 607376) dynactin subunit 2 isoform (401 aa)
initn: 2522 init1: 2522 opt: 2522 Z-score: 2370.7 bits: 447.5 E(85289): 2.6e-125
Smith-Waterman score: 2522; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:1-401)
10 20 30 40 50 60
pF1KE1 MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAEELTSTSVEHIIVNPNAAYDKFKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAEELTSTSVEHIIVNPNAAYDKFKDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 DQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMI
310 320 330 340 350 360
370 380 390 400
pF1KE1 ANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
:::::::::::::::::::::::::::::::::::::::::
NP_001 ANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
370 380 390 400
>>NP_001248341 (OMIM: 607376) dynactin subunit 2 isoform (403 aa)
initn: 2281 init1: 2281 opt: 2508 Z-score: 2357.6 bits: 445.1 E(85289): 1.4e-124
Smith-Waterman score: 2508; 99.5% identity (99.5% similar) in 403 aa overlap (1-401:1-403)
10 20 30 40 50
pF1KE1 MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAE--ELTSTSVEHIIVNPNAAYDKFK
:::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAELEELTSTSVEHIIVNPNAAYDKFK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 KIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 LQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 RCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE1 SVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQ
310 320 330 340 350 360
360 370 380 390 400
pF1KE1 MIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
:::::::::::::::::::::::::::::::::::::::::::
NP_001 MIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
370 380 390 400
>>NP_006391 (OMIM: 607376) dynactin subunit 2 isoform 1 (406 aa)
initn: 2508 init1: 2281 opt: 2502 Z-score: 2351.9 bits: 444.1 E(85289): 2.9e-124
Smith-Waterman score: 2502; 98.8% identity (98.8% similar) in 406 aa overlap (1-401:1-406)
10 20 30 40 50
pF1KE1 MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDA-----EELTSTSVEHIIVNPNAAYD
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_006 MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAFAQELEELTSTSVEHIIVNPNAAYD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 KFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 EVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 RLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 TAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE1 HKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDT
310 320 330 340 350 360
360 370 380 390 400
pF1KE1 TQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
370 380 390 400
>>XP_011536063 (OMIM: 607376) PREDICTED: dynactin subuni (314 aa)
initn: 1947 init1: 1947 opt: 1947 Z-score: 1834.3 bits: 347.9 E(85289): 2e-95
Smith-Waterman score: 1947; 100.0% identity (100.0% similar) in 314 aa overlap (88-401:1-314)
60 70 80 90 100 110
pF1KE1 KDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEV
::::::::::::::::::::::::::::::
XP_011 MLGEGLGVKETPQQKYQRLLHEVQELTTEV
10 20 30
120 130 140 150 160 170
pF1KE1 EKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRL
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE1 LLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE1 VRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHK
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE1 ASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQ
220 230 240 250 260 270
360 370 380 390 400
pF1KE1 QMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
280 290 300 310
401 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:03:12 2016 done: Sun Nov 6 21:03:13 2016
Total Scan time: 9.290 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]