FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1874, 396 aa
  1>>>pF1KE1874 396 - 396 aa - 396 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4303+/-0.000685; mu= 17.0038+/- 0.041
 mean_var=70.9158+/-14.299, 0's: 0 Z-trim(110.6): 9  B-trim: 0 in 0/51
 Lambda= 0.152301
 statistics sampled from 11702 (11705) to 11702 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.36), width:  16
 Scan time:  3.090

The best scores are:                                      opt bits E(32554)
CCDS8779.1 DHH gene_id:50846|Hs108|chr12           ( 396) 2703 602.6  2e-172
CCDS33380.1 IHH gene_id:3549|Hs108|chr2            ( 411) 1520 342.7 3.7e-94
CCDS5942.1 SHH gene_id:6469|Hs108|chr7             ( 462) 1206 273.7 2.4e-73


>>CCDS8779.1 DHH gene_id:50846|Hs108|chr12                (396 aa)
 initn: 2703 init1: 2703 opt: 2703  Z-score: 3209.0  bits: 602.6 E(32554): 2e-172
Smith-Waterman score: 2703; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)

               10        20        30        40        50        60
pF1KE1 MALLTNLLPLCCLALLALPAQSCGPGRGPVGRRRYARKQLVPLLYKQFVPGVPERTLGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 MALLTNLLPLCCLALLALPAQSCGPGRGPVGRRRYARKQLVPLLYKQFVPGVPERTLGAS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 GPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 GPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 VRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 VRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 HVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRELHRGDWVLAADASGRVVPTPVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 HVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRELHRGDWVLAADASGRVVPTPVL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 LFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAARGPAPAPGDFAPVFARRLRAGDSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 LFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAARGPAPAPGDFAPVFARRLRAGDSV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 LAPGGDALRPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 LAPGGDALRPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPL
              310       320       330       340       350       360

              370       380       390      
pF1KE1 RLLHALGALLPGGAVQPTGMHWYSRLLYRLAEELLG
       ::::::::::::::::::::::::::::::::::::
CCDS87 RLLHALGALLPGGAVQPTGMHWYSRLLYRLAEELLG
              370       380       390      

>>CCDS33380.1 IHH gene_id:3549|Hs108|chr2                 (411 aa)
 initn: 1475 init1: 1410 opt: 1520  Z-score: 1804.0  bits: 342.7 E(32554): 3.7e-94
Smith-Waterman score: 1520; 59.9% identity (81.0% similar) in 389 aa overlap (10-395:14-396)

                   10        20         30        40        50     
pF1KE1     MALLTNLLPLCCLALLALPAQ-SCGPGRGPVGRRRYARKQLVPLLYKQFVPGVPER
                    :  : ::..::  .:::::  :: ::   ..:::: :::: :.:::.
CCDS33 MSPARLRPRLHFCLVLLLLLVVPAAWGCGPGR-VVGSRRRPPRKLVPLAYKQFSPNVPEK
               10        20        30         40        50         

          60        70        80        90       100       110     
pF1KE1 TLGASGPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVM
       ::::::  ::..::.::::..:.::::::::::::::.:::::::.:::.:.:.:::.::
CCDS33 TLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVM
      60        70        80        90       100       110         

         120       130       140       150       160       170     
pF1KE1 NMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVY
       :.::::.:::::::::::::...::::::::.::::::::::::::::::::::::::::
CCDS33 NQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVY
     120       130       140       150       160       170         

         180       190       200       210       220       230     
pF1KE1 YESRNHVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRELHRGDWVLAADASGRVV
       :::. ::: :::...: :...:::::..: ::: :: : .:  .. :: :::   .:  .
CCDS33 YESKAHVHCSVKSEHSAAAKTGGCFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGSPT
     180       190       200       210       220       230         

         240       250       260       270       280       290     
pF1KE1 PTPVLLFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAARGPAPAPGDFAPVFARRLR
        . ::.::::. .:  .: ..::. :::.: ::: ::.:.: . .   . :  .:: ...
CCDS33 FSDVLIFLDREPHRLRAFQVIETQDPPRRLALTPAHLLFTADNHTEPAARFRATFASHVQ
     240       250       260       270       280       290         

         300       310       320       330       340       350     
pF1KE1 AGDSVLAPGGDALRPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHR
        :. ::. :  .:.::::: :. . :.:..:::: ::::.:.::.:::.:.. .:. :. 
CCDS33 PGQYVLVAGVPGLQPARVAAVSTHVALGAYAPLTKHGTLVVEDVVASCFAAVADHHLAQL
     300       310       320       330       340       350         

         360         370       380       390                    
pF1KE1 AFAPLRLLHAL--GALLPGGAVQPTGMHWYSRLLYRLAEELLG              
       :: ::::.:.:  :.  ::      :.::: .:::::.. ::               
CCDS33 AFWPLRLFHSLAWGSWTPG-----EGVHWYPQLLYRLGRLLLEEGSFHPLGMSGAGS
     360       370            380       390       400       410 

>>CCDS5942.1 SHH gene_id:6469|Hs108|chr7                  (462 aa)
 initn: 1421 init1: 1126 opt: 1206  Z-score: 1430.3  bits: 273.7 E(32554): 2.4e-73
Smith-Waterman score: 1456; 58.7% identity (78.2% similar) in 395 aa overlap (1-371:1-392)

               10         20        30        40        50         
pF1KE1 MALLTNLLPLCCLA-LLALPAQSCGPGRGPVGRRRYARKQLVPLLYKQFVPGVPERTLGA
       : ::.  : :  .. ::.  . .::::::  :.::. .: :.:: ::::.:.: :.::::
CCDS59 MLLLARCLLLVLVSSLLVCSGLACGPGRG-FGKRRHPKK-LTPLAYKQFIPNVAEKTLGA
               10        20         30         40        50        

      60        70        80        90       100       110         
pF1KE1 SGPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWP
       ::  ::...:.::::..:.::::::::::::::.:::::::.:::...:::::.:::.::
CCDS59 SGRYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWP
       60        70        80        90       100       110        

     120       130       140       150       160       170         
pF1KE1 GVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESR
       ::.:::::::::::::...::::::::.:::::::::.:::.:::::::::::::::::.
CCDS59 GVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESK
      120       130       140       150       160       170        

     180       190       200       210       220       230         
pF1KE1 NHVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRELHRGDWVLAADASGRVVPTPV
        :.: ::::.::.:...::::::.:::.: .:  : ...:  :: ::::: .::.. .  
CCDS59 AHIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDF
      180       190       200       210       220       230        

     240       250       260       270                      280    
pF1KE1 LLFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAA---------------RGPAPAPG
       : :::::   .  : ..::. : ..::::  ::.:.:                :: :. :
CCDS59 LTFLDRDDGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGP-PSGG
      240       250       260       270       280       290        

            290       300           310        320       330       
pF1KE1 DFAP--VFARRLRAGDSVLA----PGGDALRPARVARVA-REEAVGVFAPLTAHGTLLVN
        ..:  .:: :.: :. : .     :   : :: :  :.  :::.:..:::::.::.:.:
CCDS59 ALGPRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILIN
       300       310       320       330       340       350       

       340       350       360        370       380       390      
pF1KE1 DVLASCYAVLESHQWAHRAFAPLRLLHAL-GALLPGGAVQPTGMHWYSRLLYRLAEELLG
        ::::::::.: :.::::::::.:: ::: .:: :                         
CCDS59 RVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTA
       360       370       380       390       400       410       

CCDS59 PGAADAPGAGATAGIHWYSQLLYQIGTWLLDSEALHPLGMAVKSS
       420       430       440       450       460  




396 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 09:52:56 2016 done: Sun Nov  6 09:52:56 2016
 Total Scan time:  3.090 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]