Result of FASTA (omim) for
pFN21AE1858
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1858, 379 aa
1>>>pF1KE1858 379 - 379 aa - 379 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1509+/-0.000539; mu= 17.5709+/- 0.033
mean_var=73.0893+/-14.659, 0's: 0 Z-trim(107.1): 134 B-trim: 0 in 0/50
Lambda= 0.150019
statistics sampled from 15056 (15199) to 15056 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.535), E-opt: 0.2 (0.178), width: 16
Scan time: 7.390
The best scores are: opt bits E(85289)
XP_011512635 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 2440 538.1 1.2e-152
XP_011512636 (OMIM: 130135) PREDICTED: leukocyte e ( 379) 2440 538.1 1.2e-152
NP_109591 (OMIM: 130135) leukocyte elastase inhibi ( 379) 2440 538.1 1.2e-152
XP_011512637 (OMIM: 130135) PREDICTED: leukocyte e ( 330) 2102 464.9 1.2e-130
XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 i ( 376) 1246 279.7 7.7e-75
NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens] ( 376) 1246 279.7 7.7e-75
NP_002631 (OMIM: 601697,617115) serpin B8 isoform ( 374) 1230 276.2 8.4e-74
NP_942130 (OMIM: 601697,617115) serpin B8 isoform ( 374) 1230 276.2 8.4e-74
NP_001284629 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1217 273.4 6e-73
NP_004559 (OMIM: 173321,613453) serpin B6 isoform ( 376) 1217 273.4 6e-73
XP_011512976 (OMIM: 173321,613453) PREDICTED: serp ( 376) 1217 273.4 6e-73
NP_001284628 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1217 273.4 6e-73
XP_011512975 (OMIM: 173321,613453) PREDICTED: serp ( 376) 1217 273.4 6e-73
NP_001258754 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1217 273.4 6e-73
NP_001258753 (OMIM: 173321,613453) serpin B6 isofo ( 376) 1217 273.4 6e-73
NP_001182220 (OMIM: 173321,613453) serpin B6 isofo ( 380) 1217 273.4 6e-73
XP_016866429 (OMIM: 173321,613453) PREDICTED: serp ( 380) 1217 273.4 6e-73
NP_001258751 (OMIM: 173321,613453) serpin B6 isofo ( 390) 1217 273.4 6.1e-73
NP_001258752 (OMIM: 173321,613453) serpin B6 isofo ( 395) 1217 273.4 6.2e-73
XP_011512974 (OMIM: 173321,613453) PREDICTED: serp ( 454) 1217 273.5 6.9e-73
XP_016866431 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 1050 237.2 4e-62
XP_011512980 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 1050 237.2 4e-62
XP_016866432 (OMIM: 601799) PREDICTED: serpin B9 i ( 325) 1050 237.2 4e-62
XP_016866430 (OMIM: 173321,613453) PREDICTED: serp ( 332) 1049 237.0 4.8e-62
XP_011512978 (OMIM: 173321,613453) PREDICTED: serp ( 332) 1049 237.0 4.8e-62
NP_002630 (OMIM: 154790) serpin B5 [Homo sapiens] ( 375) 1031 233.2 7.8e-61
NP_002965 (OMIM: 600518) serpin B4 isoform 1 [Homo ( 390) 1022 231.2 3.1e-60
XP_011524440 (OMIM: 600518) PREDICTED: serpin B4 i ( 390) 1022 231.2 3.1e-60
NP_008850 (OMIM: 600517) serpin B3 [Homo sapiens] ( 390) 1021 231.0 3.6e-60
NP_001137290 (OMIM: 173390) plasminogen activator ( 415) 1021 231.0 3.8e-60
NP_002566 (OMIM: 173390) plasminogen activator inh ( 415) 1021 231.0 3.8e-60
XP_011524329 (OMIM: 602058) PREDICTED: serpin B10 ( 397) 1014 229.5 1e-59
NP_005015 (OMIM: 602058) serpin B10 [Homo sapiens] ( 397) 1014 229.5 1e-59
XP_011524331 (OMIM: 604445) PREDICTED: serpin B13 ( 390) 966 219.1 1.4e-56
NP_036529 (OMIM: 604445) serpin B13 isoform 2 [Hom ( 391) 963 218.5 2.2e-56
NP_001294852 (OMIM: 604445) serpin B13 isoform 1 [ ( 400) 963 218.5 2.2e-56
NP_536723 (OMIM: 615682) serpin B11 isoform a [Hom ( 392) 940 213.5 6.9e-55
XP_011524553 (OMIM: 615682) PREDICTED: serpin B11 ( 392) 940 213.5 6.9e-55
NP_536722 (OMIM: 615662) serpin B12 isoform 2 [Hom ( 405) 909 206.8 7.4e-53
XP_016881556 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 909 206.8 7.6e-53
XP_011524550 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 909 206.8 7.6e-53
NP_001294857 (OMIM: 615662) serpin B12 isoform 1 [ ( 425) 909 206.8 7.6e-53
XP_011524551 (OMIM: 615662) PREDICTED: serpin B12 ( 425) 909 206.8 7.6e-53
XP_011524548 (OMIM: 615662) PREDICTED: serpin B12 ( 432) 909 206.8 7.7e-53
XP_005266835 (OMIM: 615662) PREDICTED: serpin B12 ( 437) 909 206.8 7.8e-53
XP_005245255 (OMIM: 107300,613118) PREDICTED: anti ( 416) 881 200.7 5e-51
NP_000479 (OMIM: 107300,613118) antithrombin-III p ( 464) 881 200.8 5.5e-51
NP_001248760 (OMIM: 603357,615598) serpin B7 isofo ( 363) 877 199.8 8.2e-51
XP_011524330 (OMIM: 602058) PREDICTED: serpin B10 ( 268) 875 199.3 8.8e-51
NP_001027018 (OMIM: 601697,617115) serpin B8 isofo ( 242) 775 177.6 2.7e-44
>>XP_011512635 (OMIM: 130135) PREDICTED: leukocyte elast (379 aa)
initn: 2440 init1: 2440 opt: 2440 Z-score: 2861.2 bits: 538.1 E(85289): 1.2e-152
Smith-Waterman score: 2440; 100.0% identity (100.0% similar) in 379 aa overlap (1-379:1-379)
10 20 30 40 50 60
pF1KE1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF
310 320 330 340 350 360
370
pF1KE1 FIRHNSSGSILFLGRFSSP
:::::::::::::::::::
XP_011 FIRHNSSGSILFLGRFSSP
370
>>XP_011512636 (OMIM: 130135) PREDICTED: leukocyte elast (379 aa)
initn: 2440 init1: 2440 opt: 2440 Z-score: 2861.2 bits: 538.1 E(85289): 1.2e-152
Smith-Waterman score: 2440; 100.0% identity (100.0% similar) in 379 aa overlap (1-379:1-379)
10 20 30 40 50 60
pF1KE1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF
310 320 330 340 350 360
370
pF1KE1 FIRHNSSGSILFLGRFSSP
:::::::::::::::::::
XP_011 FIRHNSSGSILFLGRFSSP
370
>>NP_109591 (OMIM: 130135) leukocyte elastase inhibitor (379 aa)
initn: 2440 init1: 2440 opt: 2440 Z-score: 2861.2 bits: 538.1 E(85289): 1.2e-152
Smith-Waterman score: 2440; 100.0% identity (100.0% similar) in 379 aa overlap (1-379:1-379)
10 20 30 40 50 60
pF1KE1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF
310 320 330 340 350 360
370
pF1KE1 FIRHNSSGSILFLGRFSSP
:::::::::::::::::::
NP_109 FIRHNSSGSILFLGRFSSP
370
>>XP_011512637 (OMIM: 130135) PREDICTED: leukocyte elast (330 aa)
initn: 2102 init1: 2102 opt: 2102 Z-score: 2466.7 bits: 464.9 E(85289): 1.2e-130
Smith-Waterman score: 2102; 100.0% identity (100.0% similar) in 324 aa overlap (56-379:7-330)
30 40 50 60 70 80
pF1KE1 GNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVEEVHSRFQSLNADINKRGASYI
::::::::::::::::::::::::::::::
XP_011 MDSLHGKTFHFNTVEEVHSRFQSLNADINKRGASYI
10 20 30
90 100 110 120 130 140
pF1KE1 LKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIP
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 ELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 YGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLD
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 FIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVE
220 230 240 250 260 270
330 340 350 360 370
pF1KE1 VNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP
280 290 300 310 320 330
>>XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 isofo (376 aa)
initn: 1086 init1: 762 opt: 1246 Z-score: 1464.6 bits: 279.7 E(85289): 7.7e-75
Smith-Waterman score: 1246; 51.1% identity (77.6% similar) in 380 aa overlap (1-379:1-376)
10 20 30 40 50 60
pF1KE1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
:: ::.:. ::. :. : ..::. :.: :: :::::.:::.::..::::.:..... .
XP_005 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
:: :..: :::: ...:: :..:.:. ::::.:::: .:: : : . : :.: ..
XP_005 NTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
: .:.:..:: :: ::. .::::: ::: .. .: :.:::::::::::.:.. : . :
XP_005 FIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
. ::..:..... :.::::. : ... ... ..::::: .:::...::::: . :
XP_005 REMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
: .:..::.::: ::::. . ::.: ::.:::.:.: ..: : .::. : :...
XP_005 T----VEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQG
250 260 270 280 290
310 320 330 340 350
pF1KE1 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAG-IATFCMLMPEENFTADHPFL
:::::.::. ::. .::.::::::::::::::::::.. ... : . : ::::::
XP_005 KADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFL
300 310 320 330 340 350
360 370
pF1KE1 FFIRHNSSGSILFLGRFSSP
:::::: ..:::: ::::::
XP_005 FFIRHNRANSILFCGRFSSP
360 370
>>NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens] (376 aa)
initn: 1086 init1: 762 opt: 1246 Z-score: 1464.6 bits: 279.7 E(85289): 7.7e-75
Smith-Waterman score: 1246; 51.1% identity (77.6% similar) in 380 aa overlap (1-379:1-376)
10 20 30 40 50 60
pF1KE1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
:: ::.:. ::. :. : ..::. :.: :: :::::.:::.::..::::.:..... .
NP_004 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
:: :..: :::: ...:: :..:.:. ::::.:::: .:: : : . : :.: ..
NP_004 NTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
: .:.:..:: :: ::. .::::: ::: .. .: :.:::::::::::.:.. : . :
NP_004 FIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
. ::..:..... :.::::. : ... ... ..::::: .:::...::::: . :
NP_004 REMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
: .:..::.::: ::::. . ::.: ::.:::.:.: ..: : .::. : :...
NP_004 T----VEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQG
250 260 270 280 290
310 320 330 340 350
pF1KE1 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAG-IATFCMLMPEENFTADHPFL
:::::.::. ::. .::.::::::::::::::::::.. ... : . : ::::::
NP_004 KADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFL
300 310 320 330 340 350
360 370
pF1KE1 FFIRHNSSGSILFLGRFSSP
:::::: ..:::: ::::::
NP_004 FFIRHNRANSILFCGRFSSP
360 370
>>NP_002631 (OMIM: 601697,617115) serpin B8 isoform a [H (374 aa)
initn: 1041 init1: 575 opt: 1230 Z-score: 1445.9 bits: 276.2 E(85289): 8.4e-74
Smith-Waterman score: 1230; 52.4% identity (76.8% similar) in 380 aa overlap (1-379:1-374)
10 20 30 40 50 60
pF1KE1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
:..: :: ::..:: :.:.. . :.:.::.:::::.::::.:..:.::::.:... .
NP_002 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
..: :::: ...:. :..:.:. ::::.:::: .:::.: :: : :.: ..
NP_002 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
: . .:. :: ::.:: .::::: :.: .: :: .:::::::::::::.:...: .. :
NP_002 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
. :. :. ..:::.::... :: .:: .... .:::::: :::::::::::: .
NP_002 RGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDD----N
190 200 210 220 230
250 260 270 280 290 300
pF1KE1 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
: : .:. :: ::.. ::. :.: .:.: :::.:::::: :. : :::. : :. .
NP_002 TDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEA
240 250 260 270 280 290
310 320 330 340 350
pF1KE1 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGI-ATFCMLMPEENFTADHPFL
:::.:::: ... .::..:: :::::::::::::::: . . : : : : ::::::
NP_002 KADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRM-EPRFCADHPFL
300 310 320 330 340 350
360 370
pF1KE1 FFIRHNSSGSILFLGRFSSP
:::::.... ::: ::::::
NP_002 FFIRHHKTNCILFCGRFSSP
360 370
>>NP_942130 (OMIM: 601697,617115) serpin B8 isoform a [H (374 aa)
initn: 1041 init1: 575 opt: 1230 Z-score: 1445.9 bits: 276.2 E(85289): 8.4e-74
Smith-Waterman score: 1230; 52.4% identity (76.8% similar) in 380 aa overlap (1-379:1-374)
10 20 30 40 50 60
pF1KE1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
:..: :: ::..:: :.:.. . :.:.::.:::::.::::.:..:.::::.:... .
NP_942 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
..: :::: ...:. :..:.:. ::::.:::: .:::.: :: : :.: ..
NP_942 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
: . .:. :: ::.:: .::::: :.: .: :: .:::::::::::::.:...: .. :
NP_942 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
. :. :. ..:::.::... :: .:: .... .:::::: :::::::::::: .
NP_942 RGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDD----N
190 200 210 220 230
250 260 270 280 290 300
pF1KE1 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
: : .:. :: ::.. ::. :.: .:.: :::.:::::: :. : :::. : :. .
NP_942 TDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEA
240 250 260 270 280 290
310 320 330 340 350
pF1KE1 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGI-ATFCMLMPEENFTADHPFL
:::.:::: ... .::..:: :::::::::::::::: . . : : : : ::::::
NP_942 KADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRM-EPRFCADHPFL
300 310 320 330 340 350
360 370
pF1KE1 FFIRHNSSGSILFLGRFSSP
:::::.... ::: ::::::
NP_942 FFIRHHKTNCILFCGRFSSP
360 370
>>NP_001284629 (OMIM: 173321,613453) serpin B6 isoform a (376 aa)
initn: 998 init1: 575 opt: 1217 Z-score: 1430.7 bits: 273.4 E(85289): 6e-73
Smith-Waterman score: 1217; 51.3% identity (77.1% similar) in 384 aa overlap (1-379:1-376)
10 20 30 40 50 60
pF1KE1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
:. :. :: :::.:. .:...: . :.:.::.:.: :.:::..:..::::::... . :
NP_001 MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF
10 20 30 40 50
70 80 90 100 110
pF1KE1 NTVE---EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLA
: ..:. :::: ...:: :..:.:..::::.:::. .:: : : :: : :..
NP_001 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 SVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMK
.:: : : .:: :: :: .::::: :::. : :: .:.::::::.::.::: ..: :
NP_001 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 EATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIE
: : . :...:...: :.::.... : :: .. ..: ::: :.::.:.:.:::
NP_001 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPD---
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 DESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLF
:.: :. .:..:: ::. :::. . .: ::.:::::::::::: ..: : ::. : :
NP_001 -ETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATF-CM-LMPEENFTAD
. .:::.:::: . :. .::.::::::::::::::::::::.: . : ..:. : ::
NP_001 ELGKADFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPR--FCAD
300 310 320 330 340 350
360 370
pF1KE1 HPFLFFIRHNSSGSILFLGRFSSP
:::::::.:.....::: ::::::
NP_001 HPFLFFIQHSKTNGILFCGRFSSP
360 370
>>NP_004559 (OMIM: 173321,613453) serpin B6 isoform a [H (376 aa)
initn: 998 init1: 575 opt: 1217 Z-score: 1430.7 bits: 273.4 E(85289): 6e-73
Smith-Waterman score: 1217; 51.3% identity (77.1% similar) in 384 aa overlap (1-379:1-376)
10 20 30 40 50 60
pF1KE1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
:. :. :: :::.:. .:...: . :.:.::.:.: :.:::..:..::::::... . :
NP_004 MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF
10 20 30 40 50
70 80 90 100 110
pF1KE1 NTVE---EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLA
: ..:. :::: ...:: :..:.:..::::.:::. .:: : : :: : :..
NP_004 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 SVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMK
.:: : : .:: :: :: .::::: :::. : :: .:.::::::.::.::: ..: :
NP_004 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 EATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIE
: : . :...:...: :.::.... : :: .. ..: ::: :.::.:.:.:::
NP_004 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPD---
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 DESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLF
:.: :. .:..:: ::. :::. . .: ::.:::::::::::: ..: : ::. : :
NP_004 -ETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATF-CM-LMPEENFTAD
. .:::.:::: . :. .::.::::::::::::::::::::.: . : ..:. : ::
NP_004 ELGKADFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPR--FCAD
300 310 320 330 340 350
360 370
pF1KE1 HPFLFFIRHNSSGSILFLGRFSSP
:::::::.:.....::: ::::::
NP_004 HPFLFFIQHSKTNGILFCGRFSSP
360 370
379 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:00:59 2016 done: Sun Nov 6 17:01:00 2016
Total Scan time: 7.390 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]