Result of FASTA (omim) for
pFN21AE1850
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1850, 369 aa
1>>>pF1KE1850 369 - 369 aa - 369 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9455+/-0.000391; mu= 18.7867+/- 0.024
mean_var=68.0008+/-14.005, 0's: 0 Z-trim(113.1): 40 B-trim: 450 in 1/52
Lambda= 0.155531
statistics sampled from 22291 (22330) to 22291 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.635), E-opt: 0.2 (0.262), width: 16
Scan time: 7.090
The best scores are: opt bits E(85289)
NP_059117 (OMIM: 605196) ubiquinone biosynthesis O ( 369) 2470 563.3 3.2e-160
XP_006715563 (OMIM: 605196) PREDICTED: ubiquinone ( 410) 1956 448.0 1.8e-125
XP_016866422 (OMIM: 605196) PREDICTED: ubiquinone ( 250) 1644 377.8 1.5e-104
XP_011534201 (OMIM: 605196) PREDICTED: ubiquinone ( 250) 1644 377.8 1.5e-104
XP_005267075 (OMIM: 605196) PREDICTED: ubiquinone ( 288) 1144 265.7 9.7e-71
XP_011534200 (OMIM: 605196) PREDICTED: ubiquinone ( 329) 810 190.8 3.9e-48
>>NP_059117 (OMIM: 605196) ubiquinone biosynthesis O-met (369 aa)
initn: 2470 init1: 2470 opt: 2470 Z-score: 2997.5 bits: 563.3 E(85289): 3.2e-160
Smith-Waterman score: 2470; 99.5% identity (100.0% similar) in 369 aa overlap (1-369:1-369)
10 20 30 40 50 60
pF1KE1 MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 FKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 NDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 NDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDEN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 IKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VLKPGGSLFITTINKTQLSYALGIVFSEQIAGIVPKGTHTWEKFVSPETLESILESNGLS
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_059 VLKPGGSLFITTINKTQLSYALGIVFSEQIASIVPKGTHTWEKFVSPETLESILESNGLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VQTVVGMLYNPFSGYWHWSENTSLNYAAHAVKSRVQEHPASAEFVLKGETEELQANACTN
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_059 VQTVVGMLYNPFSGYWHWSENTSLNYAAYAVKSRVQEHPASAEFVLKGETEELQANACTN
310 320 330 340 350 360
pF1KE1 PAVHEKLKK
:::::::::
NP_059 PAVHEKLKK
>>XP_006715563 (OMIM: 605196) PREDICTED: ubiquinone bios (410 aa)
initn: 1944 init1: 1944 opt: 1956 Z-score: 2373.6 bits: 448.0 E(85289): 1.8e-125
Smith-Waterman score: 2312; 89.3% identity (89.8% similar) in 401 aa overlap (10-369:10-410)
10 20 30 40 50 60
pF1KE1 MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIW
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIW
10 20 30 40 50 60
70
pF1KE1 FKSYRTIFSCLNRIKSFR-----------------------------------------Y
:::::::::::::::::: :
XP_006 FKSYRTIFSCLNRIKSFRWSFTSVAQAGVQWCDLGSLQPPPPGFKRFSCLSLPSHWDYRY
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE1 PWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNH
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE1 QPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIE
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE1 YRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLS
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE1 YALGIVFSEQIAGIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWS
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YALGIVFSEQIASIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWS
310 320 330 340 350 360
320 330 340 350 360
pF1KE1 ENTSLNYAAHAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
:::::::::.::::::::::::::::::::::::::::::::::::::::
XP_006 ENTSLNYAAYAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
370 380 390 400 410
>>XP_016866422 (OMIM: 605196) PREDICTED: ubiquinone bios (250 aa)
initn: 1644 init1: 1644 opt: 1644 Z-score: 1998.2 bits: 377.8 E(85289): 1.5e-104
Smith-Waterman score: 1644; 99.2% identity (100.0% similar) in 250 aa overlap (120-369:1-250)
90 100 110 120 130 140
pF1KE1 TTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQPGKPLLGMK
::::::::::::::::::::::::::::::
XP_016 MNDLRVPFIRDNLLKTIPNHQPGKPLLGMK
10 20 30
150 160 170 180 190 200
pF1KE1 ILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIV
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE1 EETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQ
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE1 IAGIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAH
::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 IASIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAY
160 170 180 190 200 210
330 340 350 360
pF1KE1 AVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
::::::::::::::::::::::::::::::::::::::::
XP_016 AVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
220 230 240 250
>>XP_011534201 (OMIM: 605196) PREDICTED: ubiquinone bios (250 aa)
initn: 1644 init1: 1644 opt: 1644 Z-score: 1998.2 bits: 377.8 E(85289): 1.5e-104
Smith-Waterman score: 1644; 99.2% identity (100.0% similar) in 250 aa overlap (120-369:1-250)
90 100 110 120 130 140
pF1KE1 TTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQPGKPLLGMK
::::::::::::::::::::::::::::::
XP_011 MNDLRVPFIRDNLLKTIPNHQPGKPLLGMK
10 20 30
150 160 170 180 190 200
pF1KE1 ILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIV
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE1 EETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQ
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE1 IAGIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAH
::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 IASIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAY
160 170 180 190 200 210
330 340 350 360
pF1KE1 AVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
::::::::::::::::::::::::::::::::::::::::
XP_011 AVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
220 230 240 250
>>XP_005267075 (OMIM: 605196) PREDICTED: ubiquinone bios (288 aa)
initn: 1142 init1: 1142 opt: 1144 Z-score: 1391.0 bits: 265.7 E(85289): 9.7e-71
Smith-Waterman score: 1761; 77.5% identity (78.0% similar) in 369 aa overlap (1-369:1-288)
10 20 30 40 50 60
pF1KE1 MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 NDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDEN
:::::::::::::::::::::::::::::::::::::::::::
XP_005 NDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGGGLLTEP-----------------
130 140 150 160
190 200 210 220 230 240
pF1KE1 IKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQ
XP_005 ------------------------------------------------------------
250 260 270 280 290 300
pF1KE1 VLKPGGSLFITTINKTQLSYALGIVFSEQIAGIVPKGTHTWEKFVSPETLESILESNGLS
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_005 ----GGSLFITTINKTQLSYALGIVFSEQIASIVPKGTHTWEKFVSPETLESILESNGLS
170 180 190 200 210
310 320 330 340 350 360
pF1KE1 VQTVVGMLYNPFSGYWHWSENTSLNYAAHAVKSRVQEHPASAEFVLKGETEELQANACTN
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_005 VQTVVGMLYNPFSGYWHWSENTSLNYAAYAVKSRVQEHPASAEFVLKGETEELQANACTN
220 230 240 250 260 270
pF1KE1 PAVHEKLKK
:::::::::
XP_005 PAVHEKLKK
280
>>XP_011534200 (OMIM: 605196) PREDICTED: ubiquinone bios (329 aa)
initn: 1335 init1: 810 opt: 810 Z-score: 985.2 bits: 190.8 E(85289): 3.9e-48
Smith-Waterman score: 1669; 69.8% identity (70.2% similar) in 410 aa overlap (1-369:1-329)
10 20 30 40 50 60
pF1KE1 MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIW
10 20 30 40 50 60
70
pF1KE1 FKSYRTIFSCLNRIKSFR-----------------------------------------Y
:::::::::::::::::: :
XP_011 FKSYRTIFSCLNRIKSFRWSFTSVAQAGVQWCDLGSLQPPPPGFKRFSCLSLPSHWDYRY
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE1 PWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNH
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE1 QPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIE
::::::::::::::::::::::::
XP_011 QPGKPLLGMKILDVGCGGGLLTEP------------------------------------
190 200
200 210 220 230 240 250
pF1KE1 YRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLS
:::::::::::::::
XP_011 ---------------------------------------------GGSLFITTINKTQLS
210
260 270 280 290 300 310
pF1KE1 YALGIVFSEQIAGIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWS
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YALGIVFSEQIASIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWS
220 230 240 250 260 270
320 330 340 350 360
pF1KE1 ENTSLNYAAHAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
:::::::::.::::::::::::::::::::::::::::::::::::::::
XP_011 ENTSLNYAAYAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
280 290 300 310 320
369 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 16:42:31 2016 done: Sun Nov 6 16:42:32 2016
Total Scan time: 7.090 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]