Result of FASTA (omim) for
pFN21AE1838
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1838, 354 aa
1>>>pF1KE1838 354 - 354 aa - 354 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3208+/-0.000372; mu= 15.7446+/- 0.023
mean_var=63.6614+/-12.444, 0's: 0 Z-trim(112.7): 14 B-trim: 0 in 0/53
Lambda= 0.160745
statistics sampled from 21647 (21660) to 21647 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.635), E-opt: 0.2 (0.254), width: 16
Scan time: 8.210
The best scores are: opt bits E(85289)
NP_000296 (OMIM: 602447) serum paraoxonase/arylest ( 354) 2334 550.1 2.7e-156
XP_016867846 (OMIM: 602447) PREDICTED: serum parao ( 284) 1847 437.1 2.2e-122
XP_005250510 (OMIM: 602447) PREDICTED: serum parao ( 286) 1847 437.1 2.2e-122
XP_016867847 (OMIM: 602447) PREDICTED: serum parao ( 268) 1774 420.2 2.6e-117
NP_000437 (OMIM: 168820,612633) serum paraoxonase/ ( 355) 1634 387.8 2e-107
NP_000931 (OMIM: 602720) serum paraoxonase/lactona ( 354) 1608 381.8 1.3e-105
NP_001018171 (OMIM: 602447) serum paraoxonase/aryl ( 342) 1455 346.3 6e-95
>>NP_000296 (OMIM: 602447) serum paraoxonase/arylesteras (354 aa)
initn: 2334 init1: 2334 opt: 2334 Z-score: 2927.1 bits: 550.1 E(85289): 2.7e-156
Smith-Waterman score: 2334; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KE1 MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
310 320 330 340 350
>>XP_016867846 (OMIM: 602447) PREDICTED: serum paraoxona (284 aa)
initn: 1847 init1: 1847 opt: 1847 Z-score: 2318.2 bits: 437.1 E(85289): 2.2e-122
Smith-Waterman score: 1847; 100.0% identity (100.0% similar) in 278 aa overlap (77-354:7-284)
50 60 70 80 90 100
pF1KE1 GIEAGSEDIDILPNGLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGF
::::::::::::::::::::::::::::::
XP_016 MRAAEHFAPDKPGGILMMDLKEEKPRARELRISRGF
10 20 30
110 120 130 140 150 160
pF1KE1 DLASFNPHGISTFIDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLASFNPHGISTFIDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE1 NDITAVGPAHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDITAVGPAHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGIN
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE1 ISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPN
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE1 GQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLY
220 230 240 250 260 270
350
pF1KE1 HRALYCEL
::::::::
XP_016 HRALYCEL
280
>>XP_005250510 (OMIM: 602447) PREDICTED: serum paraoxona (286 aa)
initn: 1847 init1: 1847 opt: 1847 Z-score: 2318.1 bits: 437.1 E(85289): 2.2e-122
Smith-Waterman score: 1847; 100.0% identity (100.0% similar) in 278 aa overlap (77-354:9-286)
50 60 70 80 90 100
pF1KE1 GIEAGSEDIDILPNGLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGF
::::::::::::::::::::::::::::::
XP_005 MVWLFLVCFAPDKPGGILMMDLKEEKPRARELRISRGF
10 20 30
110 120 130 140 150 160
pF1KE1 DLASFNPHGISTFIDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLASFNPHGISTFIDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE1 NDITAVGPAHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDITAVGPAHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGIN
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE1 ISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPN
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE1 GQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLY
220 230 240 250 260 270
350
pF1KE1 HRALYCEL
::::::::
XP_005 HRALYCEL
280
>>XP_016867847 (OMIM: 602447) PREDICTED: serum paraoxona (268 aa)
initn: 1774 init1: 1774 opt: 1774 Z-score: 2227.1 bits: 420.2 E(85289): 2.6e-117
Smith-Waterman score: 1774; 100.0% identity (100.0% similar) in 268 aa overlap (87-354:1-268)
60 70 80 90 100 110
pF1KE1 ILPNGLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGI
::::::::::::::::::::::::::::::
XP_016 MMDLKEEKPRARELRISRGFDLASFNPHGI
10 20 30
120 130 140 150 160 170
pF1KE1 STFIDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STFIDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAH
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE1 FYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYV
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE1 ADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPN
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE1 NPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
220 230 240 250 260
>>NP_000437 (OMIM: 168820,612633) serum paraoxonase/aryl (355 aa)
initn: 1642 init1: 1258 opt: 1634 Z-score: 2049.7 bits: 387.8 E(85289): 2e-107
Smith-Waterman score: 1634; 65.9% identity (89.3% similar) in 355 aa overlap (1-354:1-355)
10 20 30 40 50 60
pF1KE1 MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
:..:.:. :::..:::. .. . ..::.: :::. :.::.:.:.::::.::::..::::
NP_000 MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRG-FDLASFNPHGISTF
::::.: :::.::..:: :..:: ::.:::.:: : . :: :. . ::..::::::::::
NP_000 GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 IDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYA
:.:...::.:::::. :.:::.:::.: :.:::::::..:.:::..:::.:::: :::.
NP_000 TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 TNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADI
:::::: ::.:. : ::.: :. ::::::.::.::::::: ::::::::: ::.:.:..
NP_000 TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 LAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPP
:::.::: :::.: .:: :: :...:::::.:.:: .::.::::::::.:.: :: .:::
NP_000 LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE1 SSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
.::::::::::.:.: :: :::.::.:::::.::::: :::::::..:.::::::
NP_000 ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
310 320 330 340 350
>>NP_000931 (OMIM: 602720) serum paraoxonase/lactonase 3 (354 aa)
initn: 1608 init1: 1608 opt: 1608 Z-score: 2017.2 bits: 381.8 E(85289): 1.3e-105
Smith-Waterman score: 1608; 65.5% identity (89.8% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KE1 MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
::.:::. :::..:.:.:: .::.:.:..:::::: :. .::::. .:.:::::::::.
NP_000 MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI
::::.: :::.::. .::::.:: :..:::.:..:::. :.:: ::: ::::::: ::
NP_000 GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT
:.:.::::.:::::..:.::::::::: . ::..:::.::::: :::::...:: .::::
NP_000 DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL
::::.. .:...: :.:.:. :..::: ::::::.:: :::::..: :.::.::::.
NP_000 RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS
:..::..::: : .::::::..: ::::::..::..::: .::::: .::. :.:..::.
NP_000 AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
::::::::.::::: :.::::::::::::.:::::: ::.::::..:..:::::
NP_000 SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL
310 320 330 340 350
>>NP_001018171 (OMIM: 602447) serum paraoxonase/aryleste (342 aa)
initn: 2267 init1: 1450 opt: 1455 Z-score: 1825.6 bits: 346.3 E(85289): 6e-95
Smith-Waterman score: 2216; 96.6% identity (96.6% similar) in 354 aa overlap (1-354:1-342)
10 20 30 40 50 60
pF1KE1 MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT
:: ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DN------------EFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT
130 140 150 160
190 200 210 220 230 240
pF1KE1 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS
230 240 250 260 270 280
310 320 330 340 350
pF1KE1 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
290 300 310 320 330 340
354 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:57:27 2016 done: Sun Nov 6 09:57:28 2016
Total Scan time: 8.210 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]