Result of FASTA (omim) for
pFN21AE1834
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1834, 352 aa
1>>>pF1KE1834 352 - 352 aa - 352 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2758+/-0.000349; mu= 16.1195+/- 0.022
mean_var=64.4985+/-12.682, 0's: 0 Z-trim(114.6): 70 B-trim: 132 in 1/51
Lambda= 0.159698
statistics sampled from 24440 (24510) to 24440 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.287), width: 16
Scan time: 8.440
The best scores are: opt bits E(85289)
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352) 2382 557.5 1.6e-158
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350) 823 198.3 2.1e-50
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 623 152.3 1.8e-36
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 523 129.2 1.6e-29
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 523 129.2 1.6e-29
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 523 129.3 1.8e-29
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 523 129.3 2e-29
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 327 84.1 5.5e-16
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 321 82.7 1.7e-15
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 306 79.1 1.1e-14
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 306 79.2 1.7e-14
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 302 78.4 3.9e-14
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 298 77.4 5.6e-14
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 294 76.4 1e-13
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 294 76.4 1e-13
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427) 295 76.7 1e-13
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 294 76.5 1.2e-13
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 294 76.5 1.2e-13
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 294 76.5 1.2e-13
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 294 76.5 1.2e-13
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 293 76.3 1.4e-13
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239) 281 73.4 5.9e-13
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 281 73.5 1e-12
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 281 73.5 1e-12
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 278 72.8 1.5e-12
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 267 70.3 1e-11
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 267 70.3 1e-11
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501) 267 70.3 1e-11
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 265 69.8 1.3e-11
NP_000651 (OMIM: 131300,190180,219700) transformin ( 390) 262 69.1 1.9e-11
XP_011525544 (OMIM: 131300,190180,219700) PREDICTE ( 391) 262 69.1 1.9e-11
NP_001316868 (OMIM: 107970,190230,615582) transfor ( 412) 260 68.6 2.7e-11
NP_003230 (OMIM: 107970,190230,615582) transformin ( 412) 260 68.6 2.7e-11
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 254 67.2 6e-11
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 249 66.0 8.9e-11
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 253 67.1 9.3e-11
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 248 65.9 1.9e-10
NP_003229 (OMIM: 190220,614816) transforming growt ( 414) 242 64.5 4.8e-10
NP_001129071 (OMIM: 190220,614816) transforming gr ( 442) 242 64.5 5e-10
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 230 61.7 3.3e-09
NP_004855 (OMIM: 605312) growth/differentiation fa ( 308) 225 60.5 5.6e-09
NP_005439 (OMIM: 300247,300510) bone morphogenetic ( 392) 211 57.3 6.4e-08
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276) 206 56.1 1.1e-07
NP_001275754 (OMIM: 601918) growth/differentiation ( 366) 206 56.2 1.3e-07
NP_001275753 (OMIM: 601918) growth/differentiation ( 366) 206 56.2 1.3e-07
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366) 206 56.2 1.3e-07
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366) 206 56.2 1.3e-07
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366) 206 56.2 1.3e-07
NP_001275757 (OMIM: 601918) growth/differentiation ( 366) 206 56.2 1.3e-07
NP_001275756 (OMIM: 601918) growth/differentiation ( 366) 206 56.2 1.3e-07
>>NP_005529 (OMIM: 601233) inhibin beta C chain prepropr (352 aa)
initn: 2382 init1: 2382 opt: 2382 Z-score: 2967.1 bits: 557.5 E(85289): 1.6e-158
Smith-Waterman score: 2382; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352)
10 20 30 40 50 60
pF1KE1 MTSSLLLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MTSSLLLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PTLNRPVSRAALRTALQHLHGVPQGALLEDNREQECEIISFAETGLSTINQTRLDFHFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PTLNRPVSRAALRTALQHLHGVPQGALLEDNREQECEIISFAETGLSTINQTRLDFHFSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DRTAGDREVQQASLMFFVQLPSNTTWTLKVRVLVLGPHNTNLTLATQYLLEVDASGWHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DRTAGDREVQQASLMFFVQLPSNTTWTLKVRVLVLGPHNTNLTLATQYLLEVDASGWHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PLGPEAQAACSQGHLTLELVLEGQVAQSSVILGGAAHRPFVAARVRVGGKHQIHRRGIDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLGPEAQAACSQGHLTLELVLEGQVAQSSVILGGAAHRPFVAARVRVGGKHQIHRRGIDC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLN
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 LLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
310 320 330 340 350
>>NP_113667 (OMIM: 612031) inhibin beta E chain prepropr (350 aa)
initn: 614 init1: 387 opt: 823 Z-score: 1025.9 bits: 198.3 E(85289): 2.1e-50
Smith-Waterman score: 887; 43.3% identity (69.0% similar) in 358 aa overlap (9-352:9-350)
10 20 30 40 50 60
pF1KE1 MTSSLLLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQR
.:.: . : . .:. ::.::: : ...: :.:.:::..::: ::::.:
NP_113 MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERALVLELAKQQILDGLHLTSR
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 PTLNRPVSRAALRTALQHLHGVPQGALLEDNREQECEIISFAE-TGLSTINQTRLDFHFS
: ...: .::: ::..:. : :.. : : :.:::: : .. .. : ::.:
NP_113 PRITHPPPQAALTRALRRLQ--P-GSVAPGNGE---EVISFATVTDSTSAYSSLLTFHLS
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 SDRTAGDREVQQASLMFFVQLPSNTTWTLKVRVLVLGP----HNTNLTLATQYLLEVDAS
. :. ... .: : . : ::. :: .:.. :: ... :: ... ..
NP_113 TPRS---HHLYHARLWLHV-LPT-LPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNL---
120 130 140 150 160
180 190 200 210 220
pF1KE1 GWHQLPLGPEAQAACSQGHLTLEL---VLEGQ---VAQSSVILGGAAHR-PFVAARVRVG
::: : : . . ..: : :.: :::. ..: .: :.:. ::. ..:..
NP_113 GWHTLTLPSSGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRAN
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 --GKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAG
: . .:: :. .. .:::.. .:::.:.::.:::.::::: .:.: :::: :.::
NP_113 EPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAG
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 MPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVV
::::::::.::..:::::. .. ::::::::::::::: :...:.::::.:::::
NP_113 SPGIAASFHSAVFSLLKANNPWPAST--SCCVPTARRPLSLLYLDHNGNVVKTDVPDMVV
290 300 310 320 330 340
350
pF1KE1 EACGCS
::::::
NP_113 EACGCS
350
>>NP_002184 (OMIM: 147390) inhibin beta B chain prepropr (407 aa)
initn: 709 init1: 338 opt: 623 Z-score: 775.9 bits: 152.3 E(85289): 1.8e-36
Smith-Waterman score: 776; 38.6% identity (64.6% similar) in 373 aa overlap (14-352:42-407)
10 20 30
pF1KE1 MTSSLLLAFLLLAPTTVATPRAGGQ--CPACGG---PTLELES
: ..: .:.: : .::: : ::
NP_002 ACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSP-GGSQDTCTSCGGFRRPE-ELGR
20 30 40 50 60
40 50 60 70 80
pF1KE1 QRELLLDLAKRSILDKLHLTQRPTLNRPVSRAALRTALQHLHG--VPQGALLE-------
.:. .:: ::..:.. ::.... : .::. :::..::. : . . .:
NP_002 VDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGH
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE1 -----DNREQECEIISFAET-GLSTINQTRLDFHFSSDRTAGDREVQQASLMFFVQL-PS
:..:. :::::::: ::.. ...:: : : :.. . : :::: ....: :
NP_002 ASPGADGQERVSEIISFAETDGLAS-SRVRLYF-FISNEGNQNLFVVQASLWLYLKLLPY
130 140 150 160 170 180
150 160 170 180 190
pF1KE1 --NTTWTLKVRVLVL---GPHNTNLTLATQYLLEVDASGWHQLPLGPEAQAACSQGHLTL
. :::: : :. ... . . .. :::: .:: :: .:. :
NP_002 VLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRV-DLKRSGWHTFPLTEAIQALFERGERRL
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE1 ELVLEGQVAQSSVIL------GGAAHRPFVAARVRVG-GKHQIHRRGIDCQGGSRMCCRQ
.: .. . : ... : .:::::....:.: ..:.:..::..:.: . .::::
NP_002 NLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQ
250 260 270 280 290 300
260 270 280 290 300
pF1KE1 EFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKA-NTAAG
.::.::: :::.:::: : :: :.: :.:: ..::.:: :.::::::.: . . :
NP_002 QFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPG
310 320 330 340 350 360
310 320 330 340 350
pF1KE1 TTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
:.. :::.:: .:.::.: . :::: :.:.:.:: :::.
NP_002 TVN--SCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
370 380 390 400
>>NP_002183 (OMIM: 147290) inhibin beta A chain prepropr (426 aa)
initn: 684 init1: 501 opt: 523 Z-score: 651.1 bits: 129.2 E(85289): 1.6e-29
Smith-Waterman score: 655; 34.2% identity (56.7% similar) in 383 aa overlap (38-352:50-426)
10 20 30 40 50 60
pF1KE1 AFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPV
:: :.. . .:. ::. ::: .:: ...::
NP_002 SSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-EAVKKHILNMLHLKKRPDVTQPV
20 30 40 50 60 70
70 80 90 100 110
pF1KE1 SRAALRTALQHLH----GVPQGALLEDN----------REQECEIISFAETGLSTINQTR
.::: .:...:: : . .::. :: :::.:::.: . :
NP_002 PKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA-----R
80 90 100 110 120 130
120 130 140 150 160
pF1KE1 LDFHFSSDRTAGDREV-QQASLMFFVQLPSNTTWTLKVRV------------LVLGPHNT
.:: .. ..: : ..: . .:...:. . :: . : : .
NP_002 KTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAE
140 150 160 170 180 190
170 180 190 200
pF1KE1 NLTLA---TQYLLE---VDA--SGWHQLPLGPEAQAACSQGHLTLELVL---EGQVAQSS
.. : .. :: ::: : :: .:.. : .::. .:.. . . : . .:
NP_002 EVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGAS
200 210 220 230 240 250
210 220 230
pF1KE1 VIL--------------------GGA--------AHRPFVA--ARVRVGGKHQIHRRGID
..: ::: .::::. :: :. .:::..
NP_002 LVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLE
260 270 280 290 300 310
240 250 260 270 280 290
pF1KE1 CQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVL
:.: .::...:::.:..:::.:::: : :: :.: :.:: :::: : . :::..:.
NP_002 CDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVI
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 NLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
: . . .. :::::: ::.:.:::: .::.: :: .:.:: ::::
NP_002 NHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
380 390 400 410 420
>>XP_016867665 (OMIM: 147290) PREDICTED: inhibin beta A (426 aa)
initn: 684 init1: 501 opt: 523 Z-score: 651.1 bits: 129.2 E(85289): 1.6e-29
Smith-Waterman score: 655; 34.2% identity (56.7% similar) in 383 aa overlap (38-352:50-426)
10 20 30 40 50 60
pF1KE1 AFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPV
:: :.. . .:. ::. ::: .:: ...::
XP_016 SSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-EAVKKHILNMLHLKKRPDVTQPV
20 30 40 50 60 70
70 80 90 100 110
pF1KE1 SRAALRTALQHLH----GVPQGALLEDN----------REQECEIISFAETGLSTINQTR
.::: .:...:: : . .::. :: :::.:::.: . :
XP_016 PKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA-----R
80 90 100 110 120 130
120 130 140 150 160
pF1KE1 LDFHFSSDRTAGDREV-QQASLMFFVQLPSNTTWTLKVRV------------LVLGPHNT
.:: .. ..: : ..: . .:...:. . :: . : : .
XP_016 KTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAE
140 150 160 170 180 190
170 180 190 200
pF1KE1 NLTLA---TQYLLE---VDA--SGWHQLPLGPEAQAACSQGHLTLELVL---EGQVAQSS
.. : .. :: ::: : :: .:.. : .::. .:.. . . : . .:
XP_016 EVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGAS
200 210 220 230 240 250
210 220 230
pF1KE1 VIL--------------------GGA--------AHRPFVA--ARVRVGGKHQIHRRGID
..: ::: .::::. :: :. .:::..
XP_016 LVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLE
260 270 280 290 300 310
240 250 260 270 280 290
pF1KE1 CQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVL
:.: .::...:::.:..:::.:::: : :: :.: :.:: :::: : . :::..:.
XP_016 CDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVI
320 330 340 350 360 370
300 310 320 330 340 350
pF1KE1 NLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
: . . .. :::::: ::.:.:::: .::.: :: .:.:: ::::
XP_016 NHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
380 390 400 410 420
>>XP_016867664 (OMIM: 147290) PREDICTED: inhibin beta A (483 aa)
initn: 684 init1: 501 opt: 523 Z-score: 650.3 bits: 129.3 E(85289): 1.8e-29
Smith-Waterman score: 655; 34.2% identity (56.7% similar) in 383 aa overlap (38-352:107-483)
10 20 30 40 50 60
pF1KE1 AFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPV
:: :.. . .:. ::. ::: .:: ...::
XP_016 SSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-EAVKKHILNMLHLKKRPDVTQPV
80 90 100 110 120 130
70 80 90 100 110
pF1KE1 SRAALRTALQHLH----GVPQGALLEDN----------REQECEIISFAETGLSTINQTR
.::: .:...:: : . .::. :: :::.:::.: . :
XP_016 PKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA-----R
140 150 160 170 180 190
120 130 140 150 160
pF1KE1 LDFHFSSDRTAGDREV-QQASLMFFVQLPSNTTWTLKVRV------------LVLGPHNT
.:: .. ..: : ..: . .:...:. . :: . : : .
XP_016 KTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAE
200 210 220 230 240 250
170 180 190 200
pF1KE1 NLTLA---TQYLLE---VDA--SGWHQLPLGPEAQAACSQGHLTLELVL---EGQVAQSS
.. : .. :: ::: : :: .:.. : .::. .:.. . . : . .:
XP_016 EVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGAS
260 270 280 290 300 310
210 220 230
pF1KE1 VIL--------------------GGA--------AHRPFVA--ARVRVGGKHQIHRRGID
..: ::: .::::. :: :. .:::..
XP_016 LVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLE
320 330 340 350 360 370
240 250 260 270 280 290
pF1KE1 CQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVL
:.: .::...:::.:..:::.:::: : :: :.: :.:: :::: : . :::..:.
XP_016 CDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVI
380 390 400 410 420 430
300 310 320 330 340 350
pF1KE1 NLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
: . . .. :::::: ::.:.:::: .::.: :: .:.:: ::::
XP_016 NHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
440 450 460 470 480
>>XP_016867663 (OMIM: 147290) PREDICTED: inhibin beta A (548 aa)
initn: 684 init1: 501 opt: 523 Z-score: 649.4 bits: 129.3 E(85289): 2e-29
Smith-Waterman score: 655; 34.2% identity (56.7% similar) in 383 aa overlap (38-352:172-548)
10 20 30 40 50 60
pF1KE1 AFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPV
:: :.. . .:. ::. ::: .:: ...::
XP_016 SSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-EAVKKHILNMLHLKKRPDVTQPV
150 160 170 180 190 200
70 80 90 100 110
pF1KE1 SRAALRTALQHLH----GVPQGALLEDN----------REQECEIISFAETGLSTINQTR
.::: .:...:: : . .::. :: :::.:::.: . :
XP_016 PKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA-----R
210 220 230 240 250
120 130 140 150 160
pF1KE1 LDFHFSSDRTAGDREV-QQASLMFFVQLPSNTTWTLKVRV------------LVLGPHNT
.:: .. ..: : ..: . .:...:. . :: . : : .
XP_016 KTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAE
260 270 280 290 300 310
170 180 190 200
pF1KE1 NLTLA---TQYLLE---VDA--SGWHQLPLGPEAQAACSQGHLTLELVL---EGQVAQSS
.. : .. :: ::: : :: .:.. : .::. .:.. . . : . .:
XP_016 EVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGAS
320 330 340 350 360 370
210 220 230
pF1KE1 VIL--------------------GGA--------AHRPFVA--ARVRVGGKHQIHRRGID
..: ::: .::::. :: :. .:::..
XP_016 LVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLE
380 390 400 410 420 430
240 250 260 270 280 290
pF1KE1 CQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVL
:.: .::...:::.:..:::.:::: : :: :.: :.:: :::: : . :::..:.
XP_016 CDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVI
440 450 460 470 480 490
300 310 320 330 340 350
pF1KE1 NLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
: . . .. :::::: ::.:.:::: .::.: :: .:.:: ::::
XP_016 NHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
500 510 520 530 540
>>NP_001483 (OMIM: 187500,208530,217095,602880,613854) e (372 aa)
initn: 303 init1: 279 opt: 327 Z-score: 407.9 bits: 84.1 E(85289): 5.5e-16
Smith-Waterman score: 327; 40.7% identity (67.3% similar) in 113 aa overlap (242-351:261-371)
220 230 240 250 260 270
pF1KE1 LGGAAHRPFVAARVRVGGKHQIHRRGIDCQGGSRMCCR-QEFFVDFREIGWHDWIIQPEG
:: :: ....:.:::.::: :.: :.:
NP_001 AEASLLLVTLDPRLCHPLARPRRDAEPVLGGGPGGACRARRLYVSFREVGWHRWVIAPRG
240 250 260 270 280 290
280 290 300 310 320
pF1KE1 YAMNFCIGQC--PLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLL
. :.: ::: :. ..: : : :... :..: :: .. ::::. :.:.:
NP_001 FLANYCQGQCALPVALSGSGGPPALNHAVLRALMHA--AAPGAADLPCCVPARLSPISVL
300 310 320 330 340
330 340 350
pF1KE1 YYDRDSNIVKTDIPDMVVEACGCS
..: ..:.: . ::::. :::
NP_001 FFDNSDNVVLRQYEDMVVDECGCR
350 360 370
>>NP_878248 (OMIM: 604651) growth/differentiation factor (450 aa)
initn: 290 init1: 157 opt: 321 Z-score: 399.2 bits: 82.7 E(85289): 1.7e-15
Smith-Waterman score: 321; 37.4% identity (59.9% similar) in 147 aa overlap (206-351:308-449)
180 190 200 210 220 230
pF1KE1 GWHQLPLGPEAQAACSQGHLTLELVLEGQVAQSSVILGGAAHRPFVAARVRVG-GKHQIH
:. ...:: .: . : .:.. :.
NP_878 ESLFREIRAQARALGAALASEPLPDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGA
280 290 300 310 320 330
240 250 260 270 280 290
pF1KE1 RRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASF
:: .: :: : :. . :::.:.:: :::: : : : : : . . . . .
NP_878 GRGHGRRGRSR-CSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSH--LEPTN
340 350 360 370 380 390
300 310 320 330 340 350
pF1KE1 HTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
:. . .:: :. : .. .:::::. :.:.:: : .:.: . :::::::::
NP_878 HAIIQTLL--NSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR
400 410 420 430 440 450
>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b (240 aa)
initn: 325 init1: 151 opt: 306 Z-score: 384.7 bits: 79.1 E(85289): 1.1e-14
Smith-Waterman score: 335; 26.7% identity (56.7% similar) in 240 aa overlap (140-351:5-239)
110 120 130 140 150 160
pF1KE1 NQTRLDFHFSSDRTAGDREVQQASLMFFVQLPSNTTWTLKVRVL-VLGPHNTNLTLATQY
: .:... .. . .. : ..: . .
XP_011 MQDALGNNSSFHHRINIYEIIKPATANSKFPVTR
10 20 30
170 180 190 200 210
pF1KE1 LLEV-----DASGWHQLPLGPEAQAACSQGHLTLELVLE-------GQVAQSSVILGGAA
::.. .:: :... . : .. .::: . .:.: :.. : .. .
XP_011 LLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSL
40 50 60 70 80 90
220 230 240 250 260
pF1KE1 H---------RPFVAARVRVGGKHQIHRR---GIDCQGGSRM---CCRQEFFVDFREIGW
: ::.... . : : .:.: . .:. : :. ..::: ..::
XP_011 HQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGW
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE1 HDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTA
.:::. : :: .: :.::. .: . .. :. : .:... ... .:::::
XP_011 NDWIVAPPGYHAFYCHGECPFPLADH--LNSTNHAIVQTLVNS---VNSKIPKACCVPTE
160 170 180 190 200
330 340 350
pF1KE1 RRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
.:.:: :.. ..: . :::::.:::
XP_011 LSAISMLYLDENEKVVLKNYQDMVVEGCGCR
210 220 230 240
352 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:48:59 2016 done: Sun Nov 6 14:49:00 2016
Total Scan time: 8.440 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]