Result of FASTA (omim) for
pFN21AE1829
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1829, 347 aa
1>>>pF1KE1829 347 - 347 aa - 347 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9582+/-0.000281; mu= 19.2560+/- 0.018
mean_var=71.3470+/-14.202, 0's: 0 Z-trim(119.5): 63 B-trim: 0 in 0/53
Lambda= 0.151840
statistics sampled from 33442 (33505) to 33442 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.393), width: 16
Scan time: 6.680
The best scores are: opt bits E(85289)
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 2430 540.8 1.6e-153
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 1525 342.4 5.4e-94
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 386 93.1 1.2e-18
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 382 92.2 2.1e-18
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 377 91.1 3.9e-18
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 377 91.1 3.9e-18
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 377 91.1 4.5e-18
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 377 91.1 4.5e-18
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 377 91.1 4.5e-18
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 377 91.1 4.5e-18
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 372 90.1 1e-17
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 365 88.3 1.8e-17
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 367 89.0 2.4e-17
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501) 367 89.0 2.4e-17
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 367 89.0 2.4e-17
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 365 88.5 2.7e-17
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427) 356 86.5 1.1e-16
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 352 85.7 2.1e-16
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 347 84.6 5e-16
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239) 343 83.5 5.2e-16
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 343 83.7 8.1e-16
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 343 83.7 8.4e-16
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 338 82.6 1.7e-15
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 334 81.7 2.8e-15
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 313 77.1 7.6e-14
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 313 77.1 7.6e-14
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 313 77.2 8.4e-14
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 313 77.2 9.2e-14
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 311 76.7 1.1e-13
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 302 74.8 4.4e-13
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 289 71.8 2.6e-12
NP_005439 (OMIM: 300247,300510) bone morphogenetic ( 392) 286 71.2 4.3e-12
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350) 285 70.9 4.6e-12
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276) 278 69.3 1.1e-11
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366) 278 69.4 1.4e-11
NP_001275756 (OMIM: 601918) growth/differentiation ( 366) 278 69.4 1.4e-11
NP_001275757 (OMIM: 601918) growth/differentiation ( 366) 278 69.4 1.4e-11
NP_001275754 (OMIM: 601918) growth/differentiation ( 366) 278 69.4 1.4e-11
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366) 278 69.4 1.4e-11
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366) 278 69.4 1.4e-11
NP_001275753 (OMIM: 601918) growth/differentiation ( 366) 278 69.4 1.4e-11
NP_001275755 (OMIM: 601918) growth/differentiation ( 366) 278 69.4 1.4e-11
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366) 278 69.4 1.4e-11
XP_011541610 (OMIM: 601918) PREDICTED: growth/diff ( 454) 278 69.5 1.6e-11
NP_005251 (OMIM: 601918) growth/differentiation fa ( 454) 278 69.5 1.6e-11
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 268 67.3 6.9e-11
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352) 254 64.1 5.2e-10
NP_004855 (OMIM: 605312) growth/differentiation fa ( 308) 245 62.1 1.8e-09
XP_006719257 (OMIM: 603936) PREDICTED: growth/diff ( 407) 238 60.7 6.5e-09
NP_005802 (OMIM: 603936) growth/differentiation fa ( 407) 238 60.7 6.5e-09
>>NP_060525 (OMIM: 270100,601265) nodal homolog isoform (347 aa)
initn: 2430 init1: 2430 opt: 2430 Z-score: 2877.0 bits: 540.8 E(85289): 1.6e-153
Smith-Waterman score: 2430; 99.7% identity (100.0% similar) in 347 aa overlap (1-347:1-347)
10 20 30 40 50 60
pF1KE1 MHAHCLPFLLHAWWALLQAGAATVATALLRTRGQPSSPSPLAYMLSLYRDPLPRADIIRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MHAHCLPFLLHAWWALLQAGAATVATALLRTRGQPSSPSPLAYMLSLYRDPLPRADIIRS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LQAEDVAVDGQNWTFAFDFSFLSQQEDLAWAELRLQLSSPVDLPTEGSLAIEIFHQPKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LQAEDVAVDGQNWTFAFDFSFLSQQEDLAWAELRLQLSSPVDLPTEGSLAIEIFHQPKPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TEQASDSCLERFQMDLFTVTLSQVTFSLGSMVLEVTRPLSKWLKRPGALEKQMSRVAGEC
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_060 TEQASDSCLERFQMDLFTVTLSQVTFSLGSMVLEVTRPLSKWLKHPGALEKQMSRVAGEC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 WPRPPTPPATNVLLMLYSNLSQEQRQLGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WPRPPTPPATNVLLMLYSNLSQEQRQLGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 PDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLL
250 260 270 280 290 300
310 320 330 340
pF1KE1 KRYQPHRVPSTCCAPVKTKPLSMLYVDNGRVLLDHHKDMIVEECGCL
:::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KRYQPHRVPSTCCAPVKTKPLSMLYVDNGRVLLDHHKDMIVEECGCL
310 320 330 340
>>NP_001316835 (OMIM: 270100,601265) nodal homolog isofo (214 aa)
initn: 1525 init1: 1525 opt: 1525 Z-score: 1808.4 bits: 342.4 E(85289): 5.4e-94
Smith-Waterman score: 1525; 99.5% identity (100.0% similar) in 214 aa overlap (134-347:1-214)
110 120 130 140 150 160
pF1KE1 PTEGSLAIEIFHQPKPDTEQASDSCLERFQMDLFTVTLSQVTFSLGSMVLEVTRPLSKWL
::::::::::::::::::::::::::::::
NP_001 MDLFTVTLSQVTFSLGSMVLEVTRPLSKWL
10 20 30
170 180 190 200 210 220
pF1KE1 KRPGALEKQMSRVAGECWPRPPTPPATNVLLMLYSNLSQEQRQLGGSTLLWEAESSWRAQ
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHPGALEKQMSRVAGECWPRPPTPPATNVLLMLYSNLSQEQRQLGGSTLLWEAESSWRAQ
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE1 EGQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNP
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE1 VGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVDNGRVLLDHHKDMIVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVDNGRVLLDHHKDMIVEE
160 170 180 190 200 210
pF1KE1 CGCL
::::
NP_001 CGCL
>>NP_001001557 (OMIM: 118100,601147,613094,613703,615360 (455 aa)
initn: 439 init1: 325 opt: 386 Z-score: 455.5 bits: 93.1 E(85289): 1.2e-18
Smith-Waterman score: 458; 32.2% identity (55.4% similar) in 314 aa overlap (75-346:148-454)
50 60 70 80 90 100
pF1KE1 LSLYRDPLPRADIIRSLQAEDVAVDGQNWTFAFDFSFLSQQEDLAWAELRLQLSSPVDL-
. :: :.::..:.:. ::::: ..:
NP_001 FQSSKSANTITSFVDRGLDDLSHTPLRRQKYLFDVSMLSDKEELVGAELRLFRQAPSAPW
120 130 140 150 160 170
110 120 130 140 150
pF1KE1 -PTEGSLAIEIFHQPKP---DTEQASDSCLERFQMDLFTVTLSQVTFSLGSMVLEVTRPL
: : : ...: .: :.. . . ..: : . .. ::.
NP_001 GPPAGPLHVQLFPCLSPLLLDARTLDPQGAPPAGWEVFDVWQGLRHQPWKQLCLELR---
180 190 200 210 220 230
160 170 180 190 200
pF1KE1 SKWLKRPGALE--KQMSRVAGECWPRPPT-----------PPATNVLLMLYS-----NLS
. : : :. . .:. : : :: :: .::.... ::
NP_001 AAW----GELDAGEAEARARGPQQPPPPDLRSLGFGRRVRPPQERALLVVFTRSQRKNLF
240 250 260 270 280 290
210 220 230 240
pF1KE1 QEQR-QLGGSTLLWE---AESSWRAQEGQLSWE-W----GKRHRRHHLPDR--------S
:.: :::.. ::.:: : . . : :.:.:: . .: :
NP_001 AEMREQLGSAEAAGPGAGAEGSWPPPSGAPDARPWLPSPGRRRRRTAFASRHGKRHGKKS
300 310 320 330 340 350
250 260 270 280 290 300
pF1KE1 QL-CRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRY
.: : : ..:.:. .:: .::: : .:.::.::: : :. ...::::: ::.:.. .
NP_001 RLRCSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSHLEPTNHAIIQTLMNSM
360 370 380 390 400 410
310 320 330 340
pF1KE1 QPHRVPSTCCAPVKTKPLSMLYVDNGR-VLLDHHKDMIVEECGCL
.: .: .::.:.: :.:.::.: : :. ...::.:: :::
NP_001 DPGSTPPSCCVPTKLTPISILYIDAGNNVVYKQYEDMVVESCGCR
420 430 440 450
>>NP_001711 (OMIM: 602284) bone morphogenetic protein 8B (402 aa)
initn: 324 init1: 286 opt: 382 Z-score: 451.5 bits: 92.2 E(85289): 2.1e-18
Smith-Waterman score: 398; 29.4% identity (54.1% similar) in 316 aa overlap (52-346:99-401)
30 40 50 60 70
pF1KE1 ATVATALLRTRGQPSSPSPLAYMLSLYRDPLPRADIIRS---LQAEDVAVDGQ--NWT-F
: :::.. : . .: :. : .: :
NP_001 LPASAPLFMLDLYHAMAGDDDEDGAPAERRLGRADLVMSFVNMVERDRALGHQEPHWKEF
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE1 AFDFSFLSQQEDLAWAELRLQLSSPVDLPTEGSLAIEIFHQPKPDTEQASDSCLERFQMD
::.. . : .. ::.:. . : . .: . .:. . .... :: : .:
NP_001 RFDLTQIPAGEAVTAAEFRIYKVPSIHL-LNRTLHVSMFQVVQEQSNRESDL----FFLD
130 140 150 160 170 180
140 150 160 170 180
pF1KE1 LFTVTLSQVTFSLGSMVLEVTRPLSKWL-KRPGALEKQM-----------SRVAGECWPR
: :. . . : .::.:: . :: :: : .. .:: :
NP_001 LQTLRAG----DEGWLVLDVTAASDCWLLKRHKDLGLRLYVETEDGHSVDPGLAGLLGQR
190 200 210 220 230
190 200 210 220 230 240
pF1KE1 PPTPPATNVLLMLYSNLS--QEQRQLGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHLP
: :. .. .. : . : . .:. : ..: . : :
NP_001 APRSQQPFVVTFFRASPSPIRTPRAVRPLRRRQPKKSNELPQANRLPGIFDDVHGSHG--
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE1 DRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLK
:.::. .. :.:. .:: .:.: :. :.:: ::::: :. .. :::: .:::..
NP_001 --RQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVH
300 310 320 330 340 350
310 320 330 340
pF1KE1 RYQPHRVPSTCCAPVKTKPLSMLYVDNGR-VLLDHHKDMIVEECGCL
..: ::..::::.: . :.:: :.. :.: .:..:.:. :::
NP_001 LMMPDAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH
360 370 380 390 400
>>XP_016877094 (OMIM: 112262,600625,607932) PREDICTED: b (345 aa)
initn: 310 init1: 266 opt: 377 Z-score: 446.5 bits: 91.1 E(85289): 3.9e-18
Smith-Waterman score: 381; 26.6% identity (55.5% similar) in 353 aa overlap (29-346:4-344)
10 20 30 40
pF1KE1 MHAHCLPFLLHAWWALLQAGAATVATALLRTRGQPSSPSPLA-YMLSLYR----------
:: : :::. . . :: .:::
XP_016 MFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQ
10 20 30
50 60 70 80 90
pF1KE1 ----------DPLPRADIIRSLQAED--VAVDGQN----WTFAFDFSFLSQQEDLAWAEL
: ::. .::.. :. . : . . : :..: . ..: .. :::
XP_016 IHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAEL
40 50 60 70 80 90
100 110 120 130 140
pF1KE1 RLQLSSPVDLPTE---GSLAIEIFHQPKPDTEQASDSCLERFQMDLFTV---TLSQVTFS
:: . :: . : :.:.. :: .: . . :. .: : . ::.
XP_016 RL-FREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRL-LDTRLVHHNVTRWETFD
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE1 LGSMVLEVTRPLSKWLKRPG-ALEKQMSRVAGECWPRPPTPPATNVLLMLYSNLSQEQRQ
.. ::. :: :.:. .: ..... : . . : .. : . :
XP_016 VSPAVLRWTRE-----KQPNYGLAIEVTHLH---QTRTHQGQHVRISRSLPQG-SGNWAQ
160 170 180 190 200
210 220 230 240 250 260
pF1KE1 LGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSWII
: . . .. .: . . . .:. .. ... ::. .. :::. .::..::.
XP_016 LRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIV
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE1 YPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYV
: :.:. :.:.:: :...... :::: .:.:.. . .:..::.:.. . .::::.
XP_016 APPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSS-IPKACCVPTELSAISMLYL
270 280 290 300 310 320
330 340
pF1KE1 DN-GRVLLDHHKDMIVEECGCL
:. .:.: ....:.:: :::
XP_016 DEYDKVVLKNYQEMVVEGCGCR
330 340
>>XP_016877093 (OMIM: 112262,600625,607932) PREDICTED: b (345 aa)
initn: 310 init1: 266 opt: 377 Z-score: 446.5 bits: 91.1 E(85289): 3.9e-18
Smith-Waterman score: 381; 26.6% identity (55.5% similar) in 353 aa overlap (29-346:4-344)
10 20 30 40
pF1KE1 MHAHCLPFLLHAWWALLQAGAATVATALLRTRGQPSSPSPLA-YMLSLYR----------
:: : :::. . . :: .:::
XP_016 MFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQ
10 20 30
50 60 70 80 90
pF1KE1 ----------DPLPRADIIRSLQAED--VAVDGQN----WTFAFDFSFLSQQEDLAWAEL
: ::. .::.. :. . : . . : :..: . ..: .. :::
XP_016 IHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAEL
40 50 60 70 80 90
100 110 120 130 140
pF1KE1 RLQLSSPVDLPTE---GSLAIEIFHQPKPDTEQASDSCLERFQMDLFTV---TLSQVTFS
:: . :: . : :.:.. :: .: . . :. .: : . ::.
XP_016 RL-FREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRL-LDTRLVHHNVTRWETFD
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE1 LGSMVLEVTRPLSKWLKRPG-ALEKQMSRVAGECWPRPPTPPATNVLLMLYSNLSQEQRQ
.. ::. :: :.:. .: ..... : . . : .. : . :
XP_016 VSPAVLRWTRE-----KQPNYGLAIEVTHLH---QTRTHQGQHVRISRSLPQG-SGNWAQ
160 170 180 190 200
210 220 230 240 250 260
pF1KE1 LGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSWII
: . . .. .: . . . .:. .. ... ::. .. :::. .::..::.
XP_016 LRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIV
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE1 YPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYV
: :.:. :.:.:: :...... :::: .:.:.. . .:..::.:.. . .::::.
XP_016 APPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSS-IPKACCVPTELSAISMLYL
270 280 290 300 310 320
330 340
pF1KE1 DN-GRVLLDHHKDMIVEECGCL
:. .:.: ....:.:: :::
XP_016 DEYDKVVLKNYQEMVVEGCGCR
330 340
>>XP_005268072 (OMIM: 112262,600625,607932) PREDICTED: b (408 aa)
initn: 290 init1: 266 opt: 377 Z-score: 445.5 bits: 91.1 E(85289): 4.5e-18
Smith-Waterman score: 381; 26.6% identity (55.5% similar) in 353 aa overlap (29-346:67-407)
10 20 30 40
pF1KE1 MHAHCLPFLLHAWWALLQAGAATVATALLRTRGQPSSPSPLA-YMLSLYR--------
:: : :::. . . :: .:::
XP_005 EIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEE
40 50 60 70 80 90
50 60 70 80 90
pF1KE1 ------------DPLPRADIIRSLQAED--VAVDGQN----WTFAFDFSFLSQQEDLAWA
: ::. .::.. :. . : . . : :..: . ..: .. :
XP_005 EQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSA
100 110 120 130 140 150
100 110 120 130 140
pF1KE1 ELRLQLSSPVDLPTE---GSLAIEIFHQPKPDTEQASDSCLERFQMDLFTV---TLSQVT
:::: . :: . : :.:.. :: .: . . :. .: : . :
XP_005 ELRL-FREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRL-LDTRLVHHNVTRWET
160 170 180 190 200 210
150 160 170 180 190 200
pF1KE1 FSLGSMVLEVTRPLSKWLKRPG-ALEKQMSRVAGECWPRPPTPPATNVLLMLYSNLSQEQ
:... ::. :: :.:. .: ..... : . . : .. : .
XP_005 FDVSPAVLRWTRE-----KQPNYGLAIEVTHLH---QTRTHQGQHVRISRSLPQG-SGNW
220 230 240 250 260
210 220 230 240 250 260
pF1KE1 RQLGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSW
:: . . .. .: . . . .:. .. ... ::. .. :::. .::..:
XP_005 AQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDW
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE1 IIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSML
:. : :.:. :.:.:: :...... :::: .:.:.. . .:..::.:.. . .:::
XP_005 IVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSS-IPKACCVPTELSAISML
330 340 350 360 370 380
330 340
pF1KE1 YVDN-GRVLLDHHKDMIVEECGCL
:.:. .:.: ....:.:: :::
XP_005 YLDEYDKVVLKNYQEMVVEGCGCR
390 400
>>XP_016877092 (OMIM: 112262,600625,607932) PREDICTED: b (408 aa)
initn: 290 init1: 266 opt: 377 Z-score: 445.5 bits: 91.1 E(85289): 4.5e-18
Smith-Waterman score: 381; 26.6% identity (55.5% similar) in 353 aa overlap (29-346:67-407)
10 20 30 40
pF1KE1 MHAHCLPFLLHAWWALLQAGAATVATALLRTRGQPSSPSPLA-YMLSLYR--------
:: : :::. . . :: .:::
XP_016 EIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEE
40 50 60 70 80 90
50 60 70 80 90
pF1KE1 ------------DPLPRADIIRSLQAED--VAVDGQN----WTFAFDFSFLSQQEDLAWA
: ::. .::.. :. . : . . : :..: . ..: .. :
XP_016 EQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSA
100 110 120 130 140 150
100 110 120 130 140
pF1KE1 ELRLQLSSPVDLPTE---GSLAIEIFHQPKPDTEQASDSCLERFQMDLFTV---TLSQVT
:::: . :: . : :.:.. :: .: . . :. .: : . :
XP_016 ELRL-FREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRL-LDTRLVHHNVTRWET
160 170 180 190 200 210
150 160 170 180 190 200
pF1KE1 FSLGSMVLEVTRPLSKWLKRPG-ALEKQMSRVAGECWPRPPTPPATNVLLMLYSNLSQEQ
:... ::. :: :.:. .: ..... : . . : .. : .
XP_016 FDVSPAVLRWTRE-----KQPNYGLAIEVTHLH---QTRTHQGQHVRISRSLPQG-SGNW
220 230 240 250 260
210 220 230 240 250 260
pF1KE1 RQLGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSW
:: . . .. .: . . . .:. .. ... ::. .. :::. .::..:
XP_016 AQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDW
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE1 IIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSML
:. : :.:. :.:.:: :...... :::: .:.:.. . .:..::.:.. . .:::
XP_016 IVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSS-IPKACCVPTELSAISML
330 340 350 360 370 380
330 340
pF1KE1 YVDN-GRVLLDHHKDMIVEECGCL
:.:. .:.: ....:.:: :::
XP_016 YLDEYDKVVLKNYQEMVVEGCGCR
390 400
>>NP_001193 (OMIM: 112262,600625,607932) bone morphogene (408 aa)
initn: 290 init1: 266 opt: 377 Z-score: 445.5 bits: 91.1 E(85289): 4.5e-18
Smith-Waterman score: 381; 26.6% identity (55.5% similar) in 353 aa overlap (29-346:67-407)
10 20 30 40
pF1KE1 MHAHCLPFLLHAWWALLQAGAATVATALLRTRGQPSSPSPLA-YMLSLYR--------
:: : :::. . . :: .:::
NP_001 EIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEE
40 50 60 70 80 90
50 60 70 80 90
pF1KE1 ------------DPLPRADIIRSLQAED--VAVDGQN----WTFAFDFSFLSQQEDLAWA
: ::. .::.. :. . : . . : :..: . ..: .. :
NP_001 EQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSA
100 110 120 130 140 150
100 110 120 130 140
pF1KE1 ELRLQLSSPVDLPTE---GSLAIEIFHQPKPDTEQASDSCLERFQMDLFTV---TLSQVT
:::: . :: . : :.:.. :: .: . . :. .: : . :
NP_001 ELRL-FREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRL-LDTRLVHHNVTRWET
160 170 180 190 200 210
150 160 170 180 190 200
pF1KE1 FSLGSMVLEVTRPLSKWLKRPG-ALEKQMSRVAGECWPRPPTPPATNVLLMLYSNLSQEQ
:... ::. :: :.:. .: ..... : . . : .. : .
NP_001 FDVSPAVLRWTRE-----KQPNYGLAIEVTHLH---QTRTHQGQHVRISRSLPQG-SGNW
220 230 240 250 260
210 220 230 240 250 260
pF1KE1 RQLGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSW
:: . . .. .: . . . .:. .. ... ::. .. :::. .::..:
NP_001 AQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDW
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE1 IIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSML
:. : :.:. :.:.:: :...... :::: .:.:.. . .:..::.:.. . .:::
NP_001 IVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSS-IPKACCVPTELSAISML
330 340 350 360 370 380
330 340
pF1KE1 YVDN-GRVLLDHHKDMIVEECGCL
:.:. .:.: ....:.:: :::
NP_001 YLDEYDKVVLKNYQEMVVEGCGCR
390 400
>>NP_570911 (OMIM: 112262,600625,607932) bone morphogene (408 aa)
initn: 290 init1: 266 opt: 377 Z-score: 445.5 bits: 91.1 E(85289): 4.5e-18
Smith-Waterman score: 381; 26.6% identity (55.5% similar) in 353 aa overlap (29-346:67-407)
10 20 30 40
pF1KE1 MHAHCLPFLLHAWWALLQAGAATVATALLRTRGQPSSPSPLA-YMLSLYR--------
:: : :::. . . :: .:::
NP_570 EIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEE
40 50 60 70 80 90
50 60 70 80 90
pF1KE1 ------------DPLPRADIIRSLQAED--VAVDGQN----WTFAFDFSFLSQQEDLAWA
: ::. .::.. :. . : . . : :..: . ..: .. :
NP_570 EQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSA
100 110 120 130 140 150
100 110 120 130 140
pF1KE1 ELRLQLSSPVDLPTE---GSLAIEIFHQPKPDTEQASDSCLERFQMDLFTV---TLSQVT
:::: . :: . : :.:.. :: .: . . :. .: : . :
NP_570 ELRL-FREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRL-LDTRLVHHNVTRWET
160 170 180 190 200 210
150 160 170 180 190 200
pF1KE1 FSLGSMVLEVTRPLSKWLKRPG-ALEKQMSRVAGECWPRPPTPPATNVLLMLYSNLSQEQ
:... ::. :: :.:. .: ..... : . . : .. : .
NP_570 FDVSPAVLRWTRE-----KQPNYGLAIEVTHLH---QTRTHQGQHVRISRSLPQG-SGNW
220 230 240 250 260
210 220 230 240 250 260
pF1KE1 RQLGGSTLLWEAESSWRAQEGQLSWEWGKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSW
:: . . .. .: . . . .:. .. ... ::. .. :::. .::..:
NP_570 AQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDW
270 280 290 300 310 320
270 280 290 300 310 320
pF1KE1 IIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSML
:. : :.:. :.:.:: :...... :::: .:.:.. . .:..::.:.. . .:::
NP_570 IVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSS-IPKACCVPTELSAISML
330 340 350 360 370 380
330 340
pF1KE1 YVDN-GRVLLDHHKDMIVEECGCL
:.:. .:.: ....:.:: :::
NP_570 YLDEYDKVVLKNYQEMVVEGCGCR
390 400
347 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:43:27 2016 done: Mon Nov 7 16:43:28 2016
Total Scan time: 6.680 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]