FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1815, 331 aa
  1>>>pF1KE1815 331 - 331 aa - 331 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.3962+/-0.000375; mu= 5.9216+/- 0.023
 mean_var=123.7622+/-25.060, 0's: 0 Z-trim(116.3): 21  B-trim: 288 in 2/54
 Lambda= 0.115287
 statistics sampled from 27333 (27352) to 27333 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.321), width:  16
 Scan time:  7.930

The best scores are:                                      opt bits E(85289)
NP_004392 (OMIM: 601882) DNA fragmentation factor  ( 331) 2118 363.4 3.9e-100
NP_998731 (OMIM: 601882) DNA fragmentation factor  ( 268) 1669 288.6 9.7e-78
NP_001270 (OMIM: 604440) cell death activator CIDE ( 219)  180 40.9  0.0029
NP_001305312 (OMIM: 604440) cell death activator C ( 253)  180 41.0  0.0033


>>NP_004392 (OMIM: 601882) DNA fragmentation factor subu  (331 aa)
 initn: 2118 init1: 2118 opt: 2118  Z-score: 1918.8  bits: 363.4 E(85289): 3.9e-100
Smith-Waterman score: 2118; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331)

               10        20        30        40        50        60
pF1KE1 MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 ILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQT
              250       260       270       280       290       300

              310       320       330 
pF1KE1 QSLHSLRSISASKASPPGDLQNPKRARQDPT
       :::::::::::::::::::::::::::::::
NP_004 QSLHSLRSISASKASPPGDLQNPKRARQDPT
              310       320       330 

>>NP_998731 (OMIM: 601882) DNA fragmentation factor subu  (268 aa)
 initn: 1669 init1: 1669 opt: 1669  Z-score: 1516.6  bits: 288.6 E(85289): 9.7e-78
Smith-Waterman score: 1669; 99.6% identity (100.0% similar) in 262 aa overlap (1-262:1-262)

               10        20        30        40        50        60
pF1KE1 MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 ILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQT
       :::::::::::::::::::::.                                      
NP_998 ILTALREKQAPELSLSSQDLEVGGNQGH                                
              250       260                                        

>>NP_001270 (OMIM: 604440) cell death activator CIDE-A i  (219 aa)
 initn: 151 init1: 130 opt: 180  Z-score: 179.5  bits: 40.9 E(85289): 0.0029
Smith-Waterman score: 180; 30.1% identity (55.4% similar) in 166 aa overlap (26-184:41-204)

                    10        20        30         40        50    
pF1KE1      MEVTGDAGVPESGEIRTLKPCLLRRNYSRE-QHGVAASCLEDLRSKACDILAIDK
                                     :..:  ..:: :: :..: ::. : :.:  
NP_001 LIRPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELISKTLDALVIAT
               20        30        40        50        60        70

           60        70        80        90             100        
pF1KE1 SLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNN------SDGGTAWISQ
       .:  ::::: ::::.:: ...:  : .::.:. : ...::  ..      :    . :..
NP_001 GL--VTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSPPKRSGIAR
                 80        90       100       110       120        

      110       120       130       140       150       160        
pF1KE1 ESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATV
        .::. . .    .   ::   . :  :    .    :. :. .    :.   . .   .
NP_001 VTFDLYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYSAQVTGQFL
      130       140       150       160       170       180        

      170       180       190       200       210       220        
pF1KE1 QRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGIS
         :   . .:::..::                                            
NP_001 IYLGTYMLRVLDDKEERPSLRSQAKGRFTCG                             
      190       200       210                                      

>>NP_001305312 (OMIM: 604440) cell death activator CIDE-  (253 aa)
 initn: 151 init1: 130 opt: 180  Z-score: 178.6  bits: 41.0 E(85289): 0.0033
Smith-Waterman score: 180; 30.1% identity (55.4% similar) in 166 aa overlap (26-184:75-238)

                    10        20        30         40        50    
pF1KE1      MEVTGDAGVPESGEIRTLKPCLLRRNYSRE-QHGVAASCLEDLRSKACDILAIDK
                                     :..:  ..:: :: :..: ::. : :.:  
NP_001 PSRPLTFMGSQTKRVLFTPLMHPARPFRVSNHDRSSRRGVMASSLQELISKTLDALVIAT
           50        60        70        80        90       100    

           60        70        80        90             100        
pF1KE1 SLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNN------SDGGTAWISQ
       .:  ::::: ::::.:: ...:  : .::.:. : ...::  ..      :    . :..
NP_001 GL--VTLVLEEDGTVVDTEEFFQTLGDNTHFMILEKGQKWMPGSQHVPTCSPPKRSGIAR
            110       120       130       140       150       160  

      110       120       130       140       150       160        
pF1KE1 ESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATV
        .::. . .    .   ::   . :  :    .    :. :. .    :.   . .   .
NP_001 VTFDLYRLNPKDFIGCLNVKATMYEMYSVSYDIRCTGLKGLLRSLLRFLSYSAQVTGQFL
            170       180       190       200       210       220  

      170       180       190       200       210       220        
pF1KE1 QRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGIS
         :   . .:::..::                                            
NP_001 IYLGTYMLRVLDDKEERPSLRSQAKGRFTCG                             
            230       240       250                                




331 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 19:31:19 2016 done: Sun Nov  6 19:31:20 2016
 Total Scan time:  7.930 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]