Result of FASTA (omim) for
pFN21AE1796
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1796, 313 aa
1>>>pF1KE1796 313 - 313 aa - 313 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8752+/-0.00037; mu= 7.7167+/- 0.023
mean_var=243.8435+/-48.470, 0's: 0 Z-trim(122.1): 372 B-trim: 674 in 2/53
Lambda= 0.082133
statistics sampled from 39289 (39767) to 39289 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.466), width: 16
Scan time: 8.280
The best scores are: opt bits E(85289)
NP_004099 (OMIM: 601624) ficolin-2 isoform a precu ( 313) 2226 276.0 6.9e-74
XP_011516694 (OMIM: 601624) PREDICTED: ficolin-2 i ( 302) 2075 258.1 1.6e-68
XP_006717078 (OMIM: 601624) PREDICTED: ficolin-2 i ( 264) 1748 219.3 6.9e-57
NP_056652 (OMIM: 601624) ficolin-2 isoform b precu ( 275) 1748 219.3 7.1e-57
NP_001994 (OMIM: 601252) ficolin-1 precursor [Homo ( 326) 1422 180.8 3.4e-45
NP_003656 (OMIM: 604973,613860) ficolin-3 isoform ( 299) 1021 133.2 6.4e-31
NP_775628 (OMIM: 604973,613860) ficolin-3 isoform ( 288) 956 125.5 1.3e-28
NP_116232 (OMIM: 613357) fibrinogen C domain-conta ( 461) 802 107.5 5.5e-23
NP_001138578 (OMIM: 613357) fibrinogen C domain-co ( 461) 802 107.5 5.5e-23
NP_002395 (OMIM: 600596) microfibril-associated gl ( 255) 758 102.0 1.4e-21
NP_001185624 (OMIM: 600596) microfibril-associated ( 279) 758 102.0 1.5e-21
NP_001315564 (OMIM: 601995) tenascin-R isoform 2 [ (1025) 726 98.9 4.7e-20
XP_011508251 (OMIM: 601995) PREDICTED: tenascin-R (1199) 726 98.9 5.2e-20
NP_003276 (OMIM: 601995) tenascin-R isoform 1 prec (1358) 726 99.0 5.7e-20
XP_016857708 (OMIM: 601995) PREDICTED: tenascin-R (1358) 726 99.0 5.7e-20
XP_016857707 (OMIM: 601995) PREDICTED: tenascin-R (1358) 726 99.0 5.7e-20
NP_115859 (OMIM: 600985,606408,615963) tenascin-X ( 673) 681 93.3 1.5e-18
NP_036230 (OMIM: 605001) angiopoietin-related prot ( 493) 670 91.9 2.9e-18
NP_061978 (OMIM: 600985,606408,615963) tenascin-X (4242) 681 94.3 4.8e-18
XP_005252032 (OMIM: 187380,615629) PREDICTED: tena (1564) 667 92.1 7.9e-18
XP_005252031 (OMIM: 187380,615629) PREDICTED: tena (1655) 667 92.1 8.2e-18
XP_006717164 (OMIM: 187380,615629) PREDICTED: tena (1655) 667 92.1 8.2e-18
XP_011516931 (OMIM: 187380,615629) PREDICTED: tena (1746) 667 92.1 8.5e-18
XP_011516930 (OMIM: 187380,615629) PREDICTED: tena (1746) 667 92.1 8.5e-18
XP_005252030 (OMIM: 187380,615629) PREDICTED: tena (1837) 667 92.2 8.8e-18
XP_011516928 (OMIM: 187380,615629) PREDICTED: tena (1929) 667 92.2 9.1e-18
XP_006717161 (OMIM: 187380,615629) PREDICTED: tena (2019) 667 92.2 9.3e-18
XP_011516927 (OMIM: 187380,615629) PREDICTED: tena (2019) 667 92.2 9.3e-18
XP_016870170 (OMIM: 187380,615629) PREDICTED: tena (2020) 667 92.2 9.3e-18
XP_005252029 (OMIM: 187380,615629) PREDICTED: tena (2110) 667 92.2 9.6e-18
XP_006717160 (OMIM: 187380,615629) PREDICTED: tena (2110) 667 92.2 9.6e-18
NP_002151 (OMIM: 187380,615629) tenascin precursor (2201) 667 92.3 9.9e-18
XP_016870169 (OMIM: 187380,615629) PREDICTED: tena (2292) 667 92.3 1e-17
XP_006717159 (OMIM: 187380,615629) PREDICTED: tena (2293) 667 92.3 1e-17
XP_016870168 (OMIM: 187380,615629) PREDICTED: tena (2293) 667 92.3 1e-17
XP_016870167 (OMIM: 187380,615629) PREDICTED: tena (2384) 667 92.3 1e-17
NP_004664 (OMIM: 603874) angiopoietin-related prot ( 491) 652 89.7 1.3e-17
XP_005245634 (OMIM: 603874) PREDICTED: angiopoieti ( 491) 652 89.7 1.3e-17
NP_001300980 (OMIM: 601667) angiopoietin-1 isoform ( 298) 620 85.7 1.3e-16
NP_001186788 (OMIM: 601667) angiopoietin-1 isoform ( 497) 620 85.9 1.8e-16
NP_001137 (OMIM: 601667) angiopoietin-1 isoform 1 ( 498) 620 85.9 1.8e-16
NP_001308340 (OMIM: 609336) angiopoietin-related p ( 470) 604 84.0 6.4e-16
XP_011526649 (OMIM: 609336) PREDICTED: angiopoieti ( 470) 604 84.0 6.4e-16
XP_016882836 (OMIM: 609336) PREDICTED: angiopoieti ( 470) 604 84.0 6.4e-16
XP_011526652 (OMIM: 609336) PREDICTED: angiopoieti ( 470) 604 84.0 6.4e-16
NP_114123 (OMIM: 609336) angiopoietin-related prot ( 470) 604 84.0 6.4e-16
XP_011526651 (OMIM: 609336) PREDICTED: angiopoieti ( 537) 604 84.1 7e-16
XP_011526650 (OMIM: 609336) PREDICTED: angiopoieti ( 537) 604 84.1 7e-16
XP_005260148 (OMIM: 609336) PREDICTED: angiopoieti ( 551) 604 84.1 7.1e-16
XP_016868807 (OMIM: 601922) PREDICTED: angiopoieti ( 443) 569 79.8 1.1e-14
>>NP_004099 (OMIM: 601624) ficolin-2 isoform a precursor (313 aa)
initn: 2226 init1: 2226 opt: 2226 Z-score: 1447.5 bits: 276.0 E(85289): 6.9e-74
Smith-Waterman score: 2226; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313)
10 20 30 40 50 60
pF1KE1 MELDRAVGVLGAATLLLSFLGMAWALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MELDRAVGVLGAATLLLSFLGMAWALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWHT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 HALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYN
250 260 270 280 290 300
310
pF1KE1 YSYKVSEMKVRPA
:::::::::::::
NP_004 YSYKVSEMKVRPA
310
>>XP_011516694 (OMIM: 601624) PREDICTED: ficolin-2 isofo (302 aa)
initn: 2047 init1: 2047 opt: 2075 Z-score: 1351.0 bits: 258.1 E(85289): 1.6e-68
Smith-Waterman score: 2075; 95.7% identity (97.0% similar) in 305 aa overlap (10-313:1-302)
10 20 30 40 50
pF1KE1 MELDRAVGVLGAATLLLSFLGMAWALQ-AADTCPEVKMVGLEGSDKLTILRGCPGLPGAP
.: : : :::: :.. . ::::::::::::::::::::::::::::::
XP_011 MGPALLALSFL---WTMALTEDTCPEVKMVGLEGSDKLTILRGCPGLPGAP
10 20 30 40
60 70 80 90 100 110
pF1KE1 GPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWH
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 TIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDN
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 IHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHN
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 NQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGY
230 240 250 260 270 280
300 310
pF1KE1 NYSYKVSEMKVRPA
::::::::::::::
XP_011 NYSYKVSEMKVRPA
290 300
>>XP_006717078 (OMIM: 601624) PREDICTED: ficolin-2 isofo (264 aa)
initn: 1748 init1: 1748 opt: 1748 Z-score: 1142.3 bits: 219.3 E(85289): 6.9e-57
Smith-Waterman score: 1748; 100.0% identity (100.0% similar) in 242 aa overlap (72-313:23-264)
50 60 70 80 90 100
pF1KE1 GSDKLTILRGCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTG
::::::::::::::::::::::::::::::
XP_006 MGPALLALSFLWTMALTEDTCPGERGPPGPPGKAGPPGPNGAPGEPQPCLTG
10 20 30 40 50
110 120 130 140 150 160
pF1KE1 PRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWAT
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE1 YKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNL
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE1 VLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLR
180 190 200 210 220 230
290 300 310
pF1KE1 GTHGSFANGINWKSGKGYNYSYKVSEMKVRPA
::::::::::::::::::::::::::::::::
XP_006 GTHGSFANGINWKSGKGYNYSYKVSEMKVRPA
240 250 260
>>NP_056652 (OMIM: 601624) ficolin-2 isoform b precursor (275 aa)
initn: 1949 init1: 1748 opt: 1748 Z-score: 1142.1 bits: 219.3 E(85289): 7.1e-57
Smith-Waterman score: 1877; 87.9% identity (87.9% similar) in 313 aa overlap (1-313:1-275)
10 20 30 40 50 60
pF1KE1 MELDRAVGVLGAATLLLSFLGMAWALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAPG
:::::::::::::::::::::::::::::::::
NP_056 MELDRAVGVLGAATLLLSFLGMAWALQAADTCP---------------------------
10 20 30
70 80 90 100 110 120
pF1KE1 PKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWHT
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 -----------GERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWHT
40 50 60 70 80
130 140 150 160 170 180
pF1KE1 IYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNI
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE1 HALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNN
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE1 QSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYN
210 220 230 240 250 260
310
pF1KE1 YSYKVSEMKVRPA
:::::::::::::
NP_056 YSYKVSEMKVRPA
270
>>NP_001994 (OMIM: 601252) ficolin-1 precursor [Homo sap (326 aa)
initn: 1420 init1: 1420 opt: 1422 Z-score: 932.5 bits: 180.8 E(85289): 3.4e-45
Smith-Waterman score: 1719; 77.0% identity (86.8% similar) in 326 aa overlap (1-313:1-326)
10 20 30 40 50
pF1KE1 MELDRAVGVLGAATLLLSFLGMA-WALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAP
:::. :. . : :.::. :: . ::::::::::.::::::::::::::::::::::
NP_001 MELSGATMARGLAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGSDKLTILRGCPGLPGAP
10 20 30 40 50 60
60 70 80 90 100
pF1KE1 GPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEP------------QPCLTGPRTCKD
:::::::. :.::::: :: :::::: ::.: :: : : ::::.:::
NP_001 GPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 LLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFG
:::::.:::::::::::::::::::::::::::::::::::.:::::::::::.::::::
NP_001 LLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 SRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFV
:.::::::::::::::::::.::::::::::: :.:::::.:::::::::::.:::::::
NP_001 SQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE1 EGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSF
::::.::: :::. :::::::::....::: ::::::: .::.::::: :: : : :.
NP_001 GGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESY
250 260 270 280 290 300
290 300 310
pF1KE1 ANGINWKSGKGYNYSYKVSEMKVRPA
::::::...:::.:::::::::::::
NP_001 ANGINWSAAKGYKYSYKVSEMKVRPA
310 320
>>NP_003656 (OMIM: 604973,613860) ficolin-3 isoform 1 pr (299 aa)
initn: 1213 init1: 990 opt: 1021 Z-score: 676.1 bits: 133.2 E(85289): 6.4e-31
Smith-Waterman score: 1034; 49.0% identity (73.0% similar) in 300 aa overlap (14-311:9-299)
10 20 30 40 50
pF1KE1 MELDRAVGVLGAATLLLSFLGMAWALQAAD--TCPEVKMVGLEGSDKLTILRGCPGLPGA
.: : .:: :.. . .:: . ::.: :...: .::: ::.
NP_003 MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRE--LEAS-KVVLLPSCPGAPGS
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 PGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGW
:: :: : .:::::::: :: : : : . : :::.:..::..: ::::
NP_003 PGEKGAPGP------QGPPGPPGKMGPKGEPGDPVNLLRCQEGPRNCRELLSQGATLSGW
60 70 80 90 100
120 130 140 150 160 170
pF1KE1 HTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGND
. . ::. : : :.:::::.:::: ::::: ::::::.:.:..:. :::.. .::::::.
NP_003 YHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEFWLGNE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 NIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFH
:.: :: ::. ::::.: ::. : ::.: .:.. :...:.:.:: : ::.:::::..:
NP_003 NLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLH
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 NNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKG
... :.: : :.: ...::::. .::::: .:. ::::::: . .. ::.: ::.:
NP_003 SGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSEAAAHKYGIDWASGRG
230 240 250 260 270 280
300 310
pF1KE1 YNYSYKVSEMKVRPA
.. :. .: .:
NP_003 VGHPYRRVRMMLR
290
>>NP_775628 (OMIM: 604973,613860) ficolin-3 isoform 2 pr (288 aa)
initn: 971 init1: 831 opt: 956 Z-score: 634.7 bits: 125.5 E(85289): 1.3e-28
Smith-Waterman score: 998; 48.7% identity (72.3% similar) in 300 aa overlap (14-311:9-288)
10 20 30 40 50
pF1KE1 MELDRAVGVLGAATLLLSFLGMAWALQAAD--TCPEVKMVGLEGSDKLTILRGCPGLPGA
.: : .:: :.. . .:: . ::.: :...: .::: ::.
NP_775 MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRE--LEAS-KVVLLPSCPGAPGS
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 PGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGW
:: :: : .:::::::: :: : :: :::.:..::..: ::::
NP_775 PGEKGAPGP------QGPPGPPGKMGPKG------EP-----GPRNCRELLSQGATLSGW
60 70 80 90
120 130 140 150 160 170
pF1KE1 HTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGND
. . ::. : : :.:::::.:::: ::::: ::::::.:.:..:. :::.. .::::::.
NP_775 YHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEFWLGNE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 NIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFH
:.: :: ::. ::::.: ::. : ::.: .:.. :...:.:.:: : ::.:::::..:
NP_775 NLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLH
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 NNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKG
... :.: : :.: ...::::. .::::: .:. ::::::: . .. ::.: ::.:
NP_775 SGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSEAAAHKYGIDWASGRG
220 230 240 250 260 270
300 310
pF1KE1 YNYSYKVSEMKVRPA
.. :. .: .:
NP_775 VGHPYRRVRMMLR
280
>>NP_116232 (OMIM: 613357) fibrinogen C domain-containin (461 aa)
initn: 787 init1: 391 opt: 802 Z-score: 533.7 bits: 107.5 E(85289): 5.5e-23
Smith-Waterman score: 802; 48.6% identity (71.9% similar) in 249 aa overlap (73-312:210-456)
50 60 70 80 90 100
pF1KE1 SDKLTILRGCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTG-
.:: : .:: . .:. : ::
NP_116 GRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGS
180 190 200 210 220 230
110 120 130 140 150
pF1KE1 -PRTCKDLLDRGHFLSGWHTIYLPDCRP--LTVLCDMDTDGGGWTVFQRRVDGSVDFYRD
:: : :.: :. .: .... : : . : ::: :::::::::::: ::::.:.:
NP_116 RPRDCLDVLLSGQQDDGVYSVF-PTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRG
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE1 WATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVA-----
: .:..::: :: ::: :::::.:.. ::.::: :::.. .:.: :: :.
NP_116 WDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVD
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE1 DEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVS
: . : :... . :.::::: :... :.:::.:.: . .:::....:::::.:::.:
NP_116 PEEDGYPLTVADY-SGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTS
360 370 380 390 400 410
280 290 300 310
pF1KE1 NLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA
::::.::::.:.:.:.:..:.: :..:: : ::::.::
NP_116 NLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR
420 430 440 450 460
>>NP_001138578 (OMIM: 613357) fibrinogen C domain-contai (461 aa)
initn: 787 init1: 391 opt: 802 Z-score: 533.7 bits: 107.5 E(85289): 5.5e-23
Smith-Waterman score: 802; 48.6% identity (71.9% similar) in 249 aa overlap (73-312:210-456)
50 60 70 80 90 100
pF1KE1 SDKLTILRGCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTG-
.:: : .:: . .:. : ::
NP_001 GRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGS
180 190 200 210 220 230
110 120 130 140 150
pF1KE1 -PRTCKDLLDRGHFLSGWHTIYLPDCRP--LTVLCDMDTDGGGWTVFQRRVDGSVDFYRD
:: : :.: :. .: .... : : . : ::: :::::::::::: ::::.:.:
NP_001 RPRDCLDVLLSGQQDDGVYSVF-PTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRG
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE1 WATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVA-----
: .:..::: :: ::: :::::.:.. ::.::: :::.. .:.: :: :.
NP_001 WDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVD
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE1 DEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVS
: . : :... . :.::::: :... :.:::.:.: . .:::....:::::.:::.:
NP_001 PEEDGYPLTVADY-SGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTS
360 370 380 390 400 410
280 290 300 310
pF1KE1 NLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA
::::.::::.:.:.:.:..:.: :..:: : ::::.::
NP_001 NLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR
420 430 440 450 460
>>NP_002395 (OMIM: 600596) microfibril-associated glycop (255 aa)
initn: 743 init1: 345 opt: 758 Z-score: 508.5 bits: 102.0 E(85289): 1.4e-21
Smith-Waterman score: 758; 46.9% identity (69.8% similar) in 245 aa overlap (76-313:16-255)
50 60 70 80 90 100
pF1KE1 LTILRGCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTC
:: : .: : . . :: : :
NP_002 MKALLALPLLLLLSTPPCAPQVSGIRGD----ALERFCLQQPLDC
10 20 30 40
110 120 130 140 150 160
pF1KE1 KDLLDRGHFLSGWHTIYLPD--CRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYK
:. .:. .: . :: :. :. :.::: :.:: :::::.: .:::.:.: : ::
NP_002 DDIYAQGYQSDGVYLIY-PSGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWNDYK
50 60 70 80 90 100
170 180 190 200 210
pF1KE1 QGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEA-----EK
::: ::.::: .:.: :: . :::::: :::.: .::: .:... .: .
NP_002 LGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDG
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE1 YNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGR
:.: ...: .:.:::::..:..:.::: :.:.:: . :::.. .::.:...:: .::::
NP_002 YTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGF
170 180 190 200 210 220
280 290 300 310
pF1KE1 YLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA
:: :.: :.:::::: . ::. :: : .:::.: :
NP_002 YLGGSHLSYANGINWAQWKGFYYSLKRTEMKIRRA
230 240 250
313 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:39:11 2016 done: Sun Nov 6 15:39:12 2016
Total Scan time: 8.280 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]