FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1775, 282 aa
  1>>>pF1KE1775 282 - 282 aa - 282 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0848+/-0.000697; mu= 17.6832+/- 0.042
 mean_var=75.3109+/-15.521, 0's: 0 Z-trim(111.6): 15  B-trim: 1063 in 2/50
 Lambda= 0.147790
 statistics sampled from 12476 (12487) to 12476 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.384), width:  16
 Scan time:  2.670

The best scores are:                                      opt bits E(32554)
CCDS11343.1 PNMT gene_id:5409|Hs108|chr17          ( 282) 1928 419.7 1.2e-117
CCDS5430.1 INMT gene_id:11185|Hs108|chr7           ( 263)  602 136.9 1.4e-32
CCDS56479.1 INMT gene_id:11185|Hs108|chr7          ( 262)  593 135.0 5.5e-32
CCDS8368.1 NNMT gene_id:4837|Hs108|chr11           ( 264)  592 134.8 6.4e-32


>>CCDS11343.1 PNMT gene_id:5409|Hs108|chr17               (282 aa)
 initn: 1928 init1: 1928 opt: 1928  Z-score: 2225.7  bits: 419.7 E(32554): 1.2e-117
Smith-Waterman score: 1928; 100.0% identity (100.0% similar) in 282 aa overlap (1-282:1-282)

               10        20        30        40        50        60
pF1KE1 MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 FNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVR
              190       200       210       220       230       240

              250       260       270       280  
pF1KE1 EALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL
       ::::::::::::::::::::::::::::::::::::::::::
CCDS11 EALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL
              250       260       270       280  

>>CCDS5430.1 INMT gene_id:11185|Hs108|chr7                (263 aa)
 initn: 566 init1: 429 opt: 602  Z-score: 698.1  bits: 136.9 E(32554): 1.4e-32
Smith-Waterman score: 602; 39.2% identity (70.6% similar) in 255 aa overlap (27-279:11-259)

               10        20         30        40        50         
pF1KE1 MSGADRSPNAGAAPDSAPGQAAVASAYQR-FEPRAYLRNNYAPPRGDLCNPNGVGPWKLR
                                 ::. : :: :: . :.   :.      .  ..:.
CCDS54                 MKGGFTGGDEYQKHFLPRDYLATYYSFD-GSPSPEAEMLKFNLE
                               10        20         30        40   

      60        70        80        90       100       110         
pF1KE1 CLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPG
       :: .::. : ..: ::::::::::.::.:.::. :.:::..:: . ::.:: .::..:::
CCDS54 CLHKTFGPGGLQGDTLIDIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPG
            50        60        70        80        90       100   

     120       130       140       150       160       170         
pF1KE1 AFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLP-ADAL
       :..:.   . :: .::..  :..::..::: :::::  :::  .::   .:: :: :: .
CCDS54 AYDWTPAVKFACELEGNSGRWEEKEEKLRAAVKRVLKCDVHLGNPL---APAVLPLADCV
           110       120       130       140          150       160

      180       190       200       210       220       230        
pF1KE1 VSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEE
       .. . .: .  .: ... :: ....::.:::::.   .:.   :..:. ... : . .::
CCDS54 LTLLAMECACCSLDAYRAALCNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEE
              170       180       190       200       210       220

      240       250       260       270       280   
pF1KE1 VREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL 
       :..:.. .:. ...:    .   . .....  :: :  :.:    
CCDS54 VEQAVLDAGFDIEQLLHSPQSYSVTNAANN--GVCFIVARKKPGP
              230       240       250         260   

>>CCDS56479.1 INMT gene_id:11185|Hs108|chr7               (262 aa)
 initn: 525 init1: 388 opt: 593  Z-score: 687.8  bits: 135.0 E(32554): 5.5e-32
Smith-Waterman score: 593; 39.2% identity (70.6% similar) in 255 aa overlap (27-279:11-258)

               10        20         30        40        50         
pF1KE1 MSGADRSPNAGAAPDSAPGQAAVASAYQR-FEPRAYLRNNYAPPRGDLCNPNGVGPWKLR
                                 ::. : :: :: . :.   :.      .  ..:.
CCDS56                 MKGGFTGGDEYQKHFLPRDYLATYYSFD-GSPSPEAEMLKFNLE
                               10        20         30        40   

      60        70        80        90       100       110         
pF1KE1 CLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPG
       :: .::. : ..: ::::::::::.::.:.::. :.:::..:: . ::.:: .::..:::
CCDS56 CLHKTFGPG-LQGDTLIDIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPG
            50         60        70        80        90       100  

     120       130       140       150       160       170         
pF1KE1 AFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLP-ADAL
       :..:.   . :: .::..  :..::..::: :::::  :::  .::   .:: :: :: .
CCDS56 AYDWTPAVKFACELEGNSGRWEEKEEKLRAAVKRVLKCDVHLGNPL---APAVLPLADCV
            110       120       130       140          150         

      180       190       200       210       220       230        
pF1KE1 VSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEE
       .. . .: .  .: ... :: ....::.:::::.   .:.   :..:. ... : . .::
CCDS56 LTLLAMECACCSLDAYRAALCNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEE
     160       170       180       190       200       210         

      240       250       260       270       280   
pF1KE1 VREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL 
       :..:.. .:. ...:    .   . .....  :: :  :.:    
CCDS56 VEQAVLDAGFDIEQLLHSPQSYSVTNAANN--GVCFIVARKKPGP
     220       230       240         250       260  

>>CCDS8368.1 NNMT gene_id:4837|Hs108|chr11                (264 aa)
 initn: 583 init1: 345 opt: 592  Z-score: 686.6  bits: 134.8 E(32554): 6.4e-32
Smith-Waterman score: 592; 39.7% identity (68.7% similar) in 252 aa overlap (30-280:15-260)

               10        20        30        40        50          
pF1KE1 MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNG-VGPWKLR
                                    :.:: ::.. :    :.  . .. .    :.
CCDS83                MESGFTSKDTYLSHFNPRDYLEKYY--KFGSRHSAESQILKHLLK
                              10        20          30        40   

      60        70        80        90       100       110         
pF1KE1 CLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPG
        : . :    :.:  :::::::::.:::::::  :..:..::. . : ::: .::..:: 
CCDS83 NLFKIFCLDGVKGDLLIDIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPE
            50        60        70        80        90       100   

     120       130       140       150       160       170         
pF1KE1 AFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALV
       ::.::    ..: .::.     .::..::  ::.::  :: : :::::  : : ::: ..
CCDS83 AFDWSPVVTYVCDLEGNRVKGPEKEEKLRQAVKQVLKCDVTQSQPLGA-VPLP-PADCVL
           110       120       130       140       150         160 

     180       190       200       210       220       230         
pF1KE1 SAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEV
       :..::.:. ::: .. ::: .. .::.::: :... ::. :.:. :: ... .:...: :
CCDS83 STLCLDAACPDLPTYCRALRNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAV
             170       180       190       200       210       220 

     240       250       260       270       280    
pF1KE1 REALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL  
       . :. ..:: .. ..  ..    .. . . .:.:   :.:.    
CCDS83 EAAVKEAGYTIEWFE--VISQSYSSTMANNEGLFSLVARKLSRPL
             230         240       250       260    




282 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 13:51:02 2016 done: Sun Nov  6 13:51:02 2016
 Total Scan time:  2.670 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]