Result of FASTA (omim) for
pFN21AE1774
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1774, 281 aa
1>>>pF1KE1774 281 - 281 aa - 281 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0577+/-0.000333; mu= 16.5153+/- 0.021
mean_var=67.5235+/-13.765, 0's: 0 Z-trim(114.9): 36 B-trim: 0 in 0/50
Lambda= 0.156080
statistics sampled from 25046 (25082) to 25046 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.294), width: 16
Scan time: 6.240
The best scores are: opt bits E(85289)
NP_059998 (OMIM: 615733) probable 18S rRNA (guanin ( 281) 1913 439.5 3.4e-123
XP_006715910 (OMIM: 615733) PREDICTED: probable 18 ( 304) 1713 394.5 1.3e-109
NP_001189489 (OMIM: 615733) probable 18S rRNA (gua ( 298) 1607 370.6 2e-102
XP_011514081 (OMIM: 615733) PREDICTED: probable 18 ( 248) 1456 336.5 2.9e-92
XP_011514080 (OMIM: 615733) PREDICTED: probable 18 ( 271) 1256 291.5 1.1e-78
NP_689772 (OMIM: 612546) Williams-Beuren syndrome ( 245) 149 42.2 0.0011
XP_006723683 (OMIM: 252010,612360) PREDICTED: NADH ( 247) 149 42.2 0.0011
XP_016867266 (OMIM: 612546) PREDICTED: Williams-Be ( 271) 149 42.3 0.0012
XP_016867267 (OMIM: 612546) PREDICTED: Williams-Be ( 271) 149 42.3 0.0012
XP_011527644 (OMIM: 252010,612360) PREDICTED: NADH ( 299) 149 42.3 0.0013
NP_077025 (OMIM: 252010,612360) NADH dehydrogenase ( 345) 149 42.3 0.0015
>>NP_059998 (OMIM: 615733) probable 18S rRNA (guanine-N( (281 aa)
initn: 1913 init1: 1913 opt: 1913 Z-score: 2332.8 bits: 439.5 E(85289): 3.4e-123
Smith-Waterman score: 1913; 100.0% identity (100.0% similar) in 281 aa overlap (1-281:1-281)
10 20 30 40 50 60
pF1KE1 MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 GCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 SISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNERFPLRMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 AGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNERFPLRMS
190 200 210 220 230 240
250 260 270 280
pF1KE1 RRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF
:::::::::::::::::::::::::::::::::::::::::
NP_059 RRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF
250 260 270 280
>>XP_006715910 (OMIM: 615733) PREDICTED: probable 18S rR (304 aa)
initn: 1711 init1: 1711 opt: 1713 Z-score: 2088.9 bits: 394.5 E(85289): 1.3e-109
Smith-Waterman score: 1713; 98.1% identity (98.5% similar) in 261 aa overlap (23-281:44-304)
10 20 30 40 50
pF1KE1 MASRGRRPEHGGPPELFYDETEARKYVR--NSRMIDIQTRMAGRALELLYLP
::: : .:::::::::::::::::::::
XP_006 PGNTFASEGSLNTAGRPGVGKRQVAPVAGVARKGRRIWGSRMIDIQTRMAGRALELLYLP
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE1 ENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIP
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 FKPGTFDGCISISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FKPGTFDGCISISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQ
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE1 LELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVF
200 210 220 230 240 250
240 250 260 270 280
pF1KE1 TNERFPLRMSRRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TNERFPLRMSRRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF
260 270 280 290 300
>>NP_001189489 (OMIM: 615733) probable 18S rRNA (guanine (298 aa)
initn: 1597 init1: 1597 opt: 1607 Z-score: 1960.0 bits: 370.6 E(85289): 2e-102
Smith-Waterman score: 1869; 94.3% identity (94.3% similar) in 298 aa overlap (1-281:1-298)
10 20 30 40 50 60
pF1KE1 MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATK
130 140 150 160 170 180
190 200 210 220 230
pF1KE1 AGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNER------
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNEREGGAFE
190 200 210 220 230 240
240 250 260 270 280
pF1KE1 -----------FPLRMSRRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRGIRGHQTRRFPLRMSRRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF
250 260 270 280 290
>>XP_011514081 (OMIM: 615733) PREDICTED: probable 18S rR (248 aa)
initn: 1456 init1: 1456 opt: 1456 Z-score: 1777.4 bits: 336.5 E(85289): 2.9e-92
Smith-Waterman score: 1456; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214)
10 20 30 40 50 60
pF1KE1 MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 GCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNERFPLRMS
::::::::::::::::::::::::::::::::::
XP_011 AGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEVPIKDVEAGNGEEESGMGAGEEGAAQ
190 200 210 220 230 240
250 260 270 280
pF1KE1 RRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF
XP_011 APGQGSQT
>>XP_011514080 (OMIM: 615733) PREDICTED: probable 18S rR (271 aa)
initn: 1254 init1: 1254 opt: 1256 Z-score: 1533.5 bits: 291.5 E(85289): 1.1e-78
Smith-Waterman score: 1256; 97.4% identity (97.9% similar) in 194 aa overlap (23-214:44-237)
10 20 30 40 50
pF1KE1 MASRGRRPEHGGPPELFYDETEARKYVR--NSRMIDIQTRMAGRALELLYLP
::: : .:::::::::::::::::::::
XP_011 PGNTFASEGSLNTAGRPGVGKRQVAPVAGVARKGRRIWGSRMIDIQTRMAGRALELLYLP
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE1 ENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIP
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 FKPGTFDGCISISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKPGTFDGCISISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQ
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE1 LELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVF
::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEVPIKDVEAGNGEEESG
200 210 220 230 240 250
240 250 260 270 280
pF1KE1 TNERFPLRMSRRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF
XP_011 MGAGEEGAAQAPGQGSQT
260 270
>>NP_689772 (OMIM: 612546) Williams-Beuren syndrome chro (245 aa)
initn: 128 init1: 64 opt: 149 Z-score: 186.9 bits: 42.2 E(85289): 0.0011
Smith-Waterman score: 149; 30.4% identity (51.4% similar) in 138 aa overlap (4-131:13-150)
10 20 30 40
pF1KE1 MASRGR-RPEHGGPP---ELFYDETEARKYVRN-SRMIDIQTRMAGRALEL
:.: : :: : .: . . : : .. . .. :.: :
NP_689 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 LYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWV-GLDISPAMLDEAVDREIEGDLLLGDM
. .::..::::: .. : : . :.: ::.::..: . : : .
NP_689 ALPGPPHSALILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQAQAPGLYQRLSLCTL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 GQ-GIPFKPGTFDGCISISAV---QWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVL
:: .: ::::. . ..:. : :::
NP_689 GQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGGLVCLTTRTNSSNLQYKEAL
130 140 150 160 170 180
>>XP_006723683 (OMIM: 252010,612360) PREDICTED: NADH deh (247 aa)
initn: 66 init1: 66 opt: 149 Z-score: 186.9 bits: 42.2 E(85289): 0.0011
Smith-Waterman score: 149; 30.5% identity (61.0% similar) in 105 aa overlap (34-136:74-172)
10 20 30 40 50 60
pF1KE1 RGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDIGCG
.. .:.: :. . .:.: : ::.:::
XP_006 LNIFDRDLKRKQKNWAARQPEPTKFDYLKEEVGSRIADRVYD---IPRNFP-LALDLGCG
50 60 70 80 90
70 80 90 100 110 120
pF1KE1 TGLSGSYLSDE--GHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCIS
: ..::. : :... . ::. : .. . :: .:.: . .::: .::: .:
XP_006 RGYIAQYLNKETIGKFFQA-DIAENALKNSSETEIPTVSVLADE-EFLPFKENTFDLVVS
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE1 ISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATKA
...:. . . :
XP_006 SLSLHWVNDLPRALEQIHYILKPDGVFIGAMFGGDTLYELRCSLQLAETEREGGFSPHIS
160 170 180 190 200 210
>>XP_016867266 (OMIM: 612546) PREDICTED: Williams-Beuren (271 aa)
initn: 128 init1: 64 opt: 149 Z-score: 186.3 bits: 42.3 E(85289): 0.0012
Smith-Waterman score: 149; 30.4% identity (51.4% similar) in 138 aa overlap (4-131:13-150)
10 20 30 40
pF1KE1 MASRGR-RPEHGGPP---ELFYDETEARKYVRN-SRMIDIQTRMAGRALEL
:.: : :: : .: . . : : .. . .. :.: :
XP_016 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 LYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWV-GLDISPAMLDEAVDREIEGDLLLGDM
. .::..::::: .. : : . :.: ::.::..: . : : .
XP_016 ALPGPPHSALILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQAQAPGLYQRLSLCTL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 GQ-GIPFKPGTFDGCISISAV---QWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVL
:: .: ::::. . ..:. : :::
XP_016 GQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGTTIPSRDGPGLWLLPLPHLT
130 140 150 160 170 180
>>XP_016867267 (OMIM: 612546) PREDICTED: Williams-Beuren (271 aa)
initn: 128 init1: 64 opt: 149 Z-score: 186.3 bits: 42.3 E(85289): 0.0012
Smith-Waterman score: 149; 30.4% identity (51.4% similar) in 138 aa overlap (4-131:13-150)
10 20 30 40
pF1KE1 MASRGR-RPEHGGPP---ELFYDETEARKYVRN-SRMIDIQTRMAGRALEL
:.: : :: : .: . . : : .. . .. :.: :
XP_016 MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 LYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWV-GLDISPAMLDEAVDREIEGDLLLGDM
. .::..::::: .. : : . :.: ::.::..: . : : .
XP_016 ALPGPPHSALILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQAQAPGLYQRLSLCTL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 GQ-GIPFKPGTFDGCISISAV---QWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVL
:: .: ::::. . ..:. : :::
XP_016 GQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGTTIPSRDGPGLWLLPLPHLT
130 140 150 160 170 180
>>XP_011527644 (OMIM: 252010,612360) PREDICTED: NADH deh (299 aa)
initn: 66 init1: 66 opt: 149 Z-score: 185.7 bits: 42.3 E(85289): 0.0013
Smith-Waterman score: 149; 30.5% identity (61.0% similar) in 105 aa overlap (34-136:74-172)
10 20 30 40 50 60
pF1KE1 RGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDIGCG
.. .:.: :. . .:.: : ::.:::
XP_011 LNIFDRDLKRKQKNWAARQPEPTKFDYLKEEVGSRIADRVYD---IPRNFP-LALDLGCG
50 60 70 80 90
70 80 90 100 110 120
pF1KE1 TGLSGSYLSDE--GHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCIS
: ..::. : :... . ::. : .. . :: .:.: . .::: .::: .:
XP_011 RGYIAQYLNKETIGKFFQA-DIAENALKNSSETEIPTVSVLADE-EFLPFKENTFDLVVS
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE1 ISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATKA
...:. . . :
XP_011 SLSLHWVNDLPRALEQIHYILKPDGVFIGAMFGGDTLYELRCSLQLAETEREGGFSPHIS
160 170 180 190 200 210
281 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 16:24:04 2016 done: Sun Nov 6 16:24:05 2016
Total Scan time: 6.240 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]