Result of FASTA (omim) for
pFN21AE1765
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1765, 270 aa
1>>>pF1KE1765 270 - 270 aa - 270 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3621+/-0.000389; mu= 14.6749+/- 0.024
mean_var=65.2726+/-13.085, 0's: 0 Z-trim(112.3): 37 B-trim: 1268 in 1/52
Lambda= 0.158748
statistics sampled from 21075 (21111) to 21075 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.623), E-opt: 0.2 (0.248), width: 16
Scan time: 6.190
The best scores are: opt bits E(85289)
NP_001300973 (OMIM: 608678) interleukin-33 isoform ( 270) 1797 420.3 1.8e-117
NP_254274 (OMIM: 608678) interleukin-33 isoform a ( 270) 1797 420.3 1.8e-117
NP_001300974 (OMIM: 608678) interleukin-33 isoform ( 270) 1797 420.3 1.8e-117
XP_016870774 (OMIM: 608678) PREDICTED: interleukin ( 264) 1737 406.6 2.5e-113
NP_001300975 (OMIM: 608678) interleukin-33 isoform ( 264) 1737 406.6 2.5e-113
NP_001300976 (OMIM: 608678) interleukin-33 isoform ( 264) 1737 406.6 2.5e-113
XP_011516363 (OMIM: 608678) PREDICTED: interleukin ( 229) 1523 357.5 1.2e-98
NP_001300977 (OMIM: 608678) interleukin-33 isoform ( 228) 1044 247.8 1.3e-65
NP_001186569 (OMIM: 608678) interleukin-33 isoform ( 228) 789 189.4 5e-48
NP_001186570 (OMIM: 608678) interleukin-33 isoform ( 144) 774 185.9 3.6e-47
>>NP_001300973 (OMIM: 608678) interleukin-33 isoform a p (270 aa)
initn: 1797 init1: 1797 opt: 1797 Z-score: 2229.8 bits: 420.3 E(85289): 1.8e-117
Smith-Waterman score: 1797; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)
10 20 30 40 50 60
pF1KE1 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
190 200 210 220 230 240
250 260 270
pF1KE1 GVKDNHLALIKVDSSENLCTENILFKLSET
::::::::::::::::::::::::::::::
NP_001 GVKDNHLALIKVDSSENLCTENILFKLSET
250 260 270
>>NP_254274 (OMIM: 608678) interleukin-33 isoform a prec (270 aa)
initn: 1797 init1: 1797 opt: 1797 Z-score: 2229.8 bits: 420.3 E(85289): 1.8e-117
Smith-Waterman score: 1797; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)
10 20 30 40 50 60
pF1KE1 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_254 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_254 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_254 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_254 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
190 200 210 220 230 240
250 260 270
pF1KE1 GVKDNHLALIKVDSSENLCTENILFKLSET
::::::::::::::::::::::::::::::
NP_254 GVKDNHLALIKVDSSENLCTENILFKLSET
250 260 270
>>NP_001300974 (OMIM: 608678) interleukin-33 isoform a p (270 aa)
initn: 1797 init1: 1797 opt: 1797 Z-score: 2229.8 bits: 420.3 E(85289): 1.8e-117
Smith-Waterman score: 1797; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)
10 20 30 40 50 60
pF1KE1 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
190 200 210 220 230 240
250 260 270
pF1KE1 GVKDNHLALIKVDSSENLCTENILFKLSET
::::::::::::::::::::::::::::::
NP_001 GVKDNHLALIKVDSSENLCTENILFKLSET
250 260 270
>>XP_016870774 (OMIM: 608678) PREDICTED: interleukin-33 (264 aa)
initn: 1015 init1: 1015 opt: 1737 Z-score: 2155.7 bits: 406.6 E(85289): 2.5e-113
Smith-Waterman score: 1737; 97.8% identity (97.8% similar) in 270 aa overlap (1-270:1-264)
10 20 30 40 50 60
pF1KE1 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
:::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSS------IT
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
180 190 200 210 220 230
250 260 270
pF1KE1 GVKDNHLALIKVDSSENLCTENILFKLSET
::::::::::::::::::::::::::::::
XP_016 GVKDNHLALIKVDSSENLCTENILFKLSET
240 250 260
>>NP_001300975 (OMIM: 608678) interleukin-33 isoform d [ (264 aa)
initn: 1015 init1: 1015 opt: 1737 Z-score: 2155.7 bits: 406.6 E(85289): 2.5e-113
Smith-Waterman score: 1737; 97.8% identity (97.8% similar) in 270 aa overlap (1-270:1-264)
10 20 30 40 50 60
pF1KE1 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
:::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_001 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSS------IT
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
180 190 200 210 220 230
250 260 270
pF1KE1 GVKDNHLALIKVDSSENLCTENILFKLSET
::::::::::::::::::::::::::::::
NP_001 GVKDNHLALIKVDSSENLCTENILFKLSET
240 250 260
>>NP_001300976 (OMIM: 608678) interleukin-33 isoform d [ (264 aa)
initn: 1015 init1: 1015 opt: 1737 Z-score: 2155.7 bits: 406.6 E(85289): 2.5e-113
Smith-Waterman score: 1737; 97.8% identity (97.8% similar) in 270 aa overlap (1-270:1-264)
10 20 30 40 50 60
pF1KE1 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
:::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_001 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSS------IT
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
180 190 200 210 220 230
250 260 270
pF1KE1 GVKDNHLALIKVDSSENLCTENILFKLSET
::::::::::::::::::::::::::::::
NP_001 GVKDNHLALIKVDSSENLCTENILFKLSET
240 250 260
>>XP_011516363 (OMIM: 608678) PREDICTED: interleukin-33 (229 aa)
initn: 1523 init1: 1523 opt: 1523 Z-score: 1891.8 bits: 357.5 E(85289): 1.2e-98
Smith-Waterman score: 1523; 100.0% identity (100.0% similar) in 229 aa overlap (42-270:1-229)
20 30 40 50 60 70
pF1KE1 ISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYFRRETTKRPSLK
::::::::::::::::::::::::::::::
XP_011 MYFMKLRSGLMIKKEACYFRRETTKRPSLK
10 20 30
80 90 100 110 120 130
pF1KE1 TGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPITEYLASLSTYND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPITEYLASLSTYND
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE1 QSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGKMLMVTLSPTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGKMLMVTLSPTKD
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE1 FWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFIGVKDNHLALIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFIGVKDNHLALIK
160 170 180 190 200 210
260 270
pF1KE1 VDSSENLCTENILFKLSET
:::::::::::::::::::
XP_011 VDSSENLCTENILFKLSET
220
>>NP_001300977 (OMIM: 608678) interleukin-33 isoform e [ (228 aa)
initn: 1044 init1: 1044 opt: 1044 Z-score: 1298.9 bits: 247.8 E(85289): 1.3e-65
Smith-Waterman score: 1423; 84.4% identity (84.4% similar) in 270 aa overlap (1-270:1-228)
10 20 30 40 50 60
pF1KE1 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
::::::::::::: :::::
NP_001 RRETTKRPSLKTG------------------------------------------ISPIT
70
130 140 150 160 170 180
pF1KE1 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE1 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
140 150 160 170 180 190
250 260 270
pF1KE1 GVKDNHLALIKVDSSENLCTENILFKLSET
::::::::::::::::::::::::::::::
NP_001 GVKDNHLALIKVDSSENLCTENILFKLSET
200 210 220
>>NP_001186569 (OMIM: 608678) interleukin-33 isoform b [ (228 aa)
initn: 789 init1: 789 opt: 789 Z-score: 983.3 bits: 189.4 E(85289): 5e-48
Smith-Waterman score: 1444; 84.4% identity (84.4% similar) in 270 aa overlap (1-270:1-228)
10 20 30 40 50 60
pF1KE1 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSIT------
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
::::::::::::::::::::::::
NP_001 ------------------------------------DKVLLSYYESQHPSNESGDGVDGK
120 130
190 200 210 220 230 240
pF1KE1 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
140 150 160 170 180 190
250 260 270
pF1KE1 GVKDNHLALIKVDSSENLCTENILFKLSET
::::::::::::::::::::::::::::::
NP_001 GVKDNHLALIKVDSSENLCTENILFKLSET
200 210 220
>>NP_001186570 (OMIM: 608678) interleukin-33 isoform c [ (144 aa)
initn: 958 init1: 774 opt: 774 Z-score: 967.8 bits: 185.9 E(85289): 3.6e-47
Smith-Waterman score: 774; 99.1% identity (100.0% similar) in 114 aa overlap (157-270:31-144)
130 140 150 160 170 180
pF1KE1 STYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGKMLMVTL
.:::::::::::::::::::::::::::::
NP_001 MKPKMKYSTNKISTAKWKNTASKALCFKLGNKVLLSYYESQHPSNESGDGVDGKMLMVTL
10 20 30 40 50 60
190 200 210 220 230 240
pF1KE1 SPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFIGVKDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFIGVKDNH
70 80 90 100 110 120
250 260 270
pF1KE1 LALIKVDSSENLCTENILFKLSET
::::::::::::::::::::::::
NP_001 LALIKVDSSENLCTENILFKLSET
130 140
270 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:51:47 2016 done: Sun Nov 6 15:51:47 2016
Total Scan time: 6.190 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]