Result of FASTA (omim) for
pFN21AE1755
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1755, 261 aa
1>>>pF1KE1755 261 - 261 aa - 261 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0807+/-0.000303; mu= 16.5959+/- 0.019
mean_var=68.3565+/-13.427, 0's: 0 Z-trim(117.9): 23 B-trim: 0 in 0/55
Lambda= 0.155126
statistics sampled from 30395 (30418) to 30395 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.357), width: 16
Scan time: 7.400
The best scores are: opt bits E(85289)
NP_001138847 (OMIM: 610602) DNA oxidative demethyl ( 261) 1784 407.6 1.2e-113
NP_001138846 (OMIM: 610602) DNA oxidative demethyl ( 261) 1784 407.6 1.2e-113
XP_005253892 (OMIM: 610602) PREDICTED: DNA oxidati ( 261) 1784 407.6 1.2e-113
NP_001001655 (OMIM: 610602) DNA oxidative demethyl ( 261) 1784 407.6 1.2e-113
NP_001192108 (OMIM: 610602) DNA oxidative demethyl ( 157) 653 154.3 1.2e-37
NP_001192109 (OMIM: 610602) DNA oxidative demethyl ( 157) 653 154.3 1.2e-37
XP_005253893 (OMIM: 610602) PREDICTED: DNA oxidati ( 157) 653 154.3 1.2e-37
NP_631917 (OMIM: 610603) alpha-ketoglutarate-depen ( 286) 377 92.7 7.7e-19
>>NP_001138847 (OMIM: 610602) DNA oxidative demethylase (261 aa)
initn: 1784 init1: 1784 opt: 1784 Z-score: 2161.5 bits: 407.6 E(85289): 1.2e-113
Smith-Waterman score: 1784; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)
10 20 30 40 50 60
pF1KE1 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPV
190 200 210 220 230 240
250 260
pF1KE1 RKKVLAPRVNLTFRKILLTKK
:::::::::::::::::::::
NP_001 RKKVLAPRVNLTFRKILLTKK
250 260
>>NP_001138846 (OMIM: 610602) DNA oxidative demethylase (261 aa)
initn: 1784 init1: 1784 opt: 1784 Z-score: 2161.5 bits: 407.6 E(85289): 1.2e-113
Smith-Waterman score: 1784; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)
10 20 30 40 50 60
pF1KE1 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPV
190 200 210 220 230 240
250 260
pF1KE1 RKKVLAPRVNLTFRKILLTKK
:::::::::::::::::::::
NP_001 RKKVLAPRVNLTFRKILLTKK
250 260
>>XP_005253892 (OMIM: 610602) PREDICTED: DNA oxidative d (261 aa)
initn: 1784 init1: 1784 opt: 1784 Z-score: 2161.5 bits: 407.6 E(85289): 1.2e-113
Smith-Waterman score: 1784; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)
10 20 30 40 50 60
pF1KE1 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPV
190 200 210 220 230 240
250 260
pF1KE1 RKKVLAPRVNLTFRKILLTKK
:::::::::::::::::::::
XP_005 RKKVLAPRVNLTFRKILLTKK
250 260
>>NP_001001655 (OMIM: 610602) DNA oxidative demethylase (261 aa)
initn: 1784 init1: 1784 opt: 1784 Z-score: 2161.5 bits: 407.6 E(85289): 1.2e-113
Smith-Waterman score: 1784; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)
10 20 30 40 50 60
pF1KE1 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPV
190 200 210 220 230 240
250 260
pF1KE1 RKKVLAPRVNLTFRKILLTKK
:::::::::::::::::::::
NP_001 RKKVLAPRVNLTFRKILLTKK
250 260
>>NP_001192108 (OMIM: 610602) DNA oxidative demethylase (157 aa)
initn: 653 init1: 653 opt: 653 Z-score: 796.7 bits: 154.3 E(85289): 1.2e-37
Smith-Waterman score: 653; 75.2% identity (82.5% similar) in 137 aa overlap (1-137:1-137)
10 20 30 40 50 60
pF1KE1 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
:::::::::::::::::::::::::::::::::: : . :. . . .. . :
NP_001 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGIKMAVTTSGSTEMMKENWPLGAPLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
. . . ::: :::
NP_001 SPSVPAETLSSGIRIPVGKAPPGGWRWSGCRWPTGAY
130 140 150
>>NP_001192109 (OMIM: 610602) DNA oxidative demethylase (157 aa)
initn: 653 init1: 653 opt: 653 Z-score: 796.7 bits: 154.3 E(85289): 1.2e-37
Smith-Waterman score: 653; 75.2% identity (82.5% similar) in 137 aa overlap (1-137:1-137)
10 20 30 40 50 60
pF1KE1 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
:::::::::::::::::::::::::::::::::: : . :. . . .. . :
NP_001 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGIKMAVTTSGSTEMMKENWPLGAPLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
. . . ::: :::
NP_001 SPSVPAETLSSGIRIPVGKAPPGGWRWSGCRWPTGAY
130 140 150
>>XP_005253893 (OMIM: 610602) PREDICTED: DNA oxidative d (157 aa)
initn: 653 init1: 653 opt: 653 Z-score: 796.7 bits: 154.3 E(85289): 1.2e-37
Smith-Waterman score: 653; 75.2% identity (82.5% similar) in 137 aa overlap (1-137:1-137)
10 20 30 40 50 60
pF1KE1 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGL
:::::::::::::::::::::::::::::::::: : . :. . . .. . :
XP_005 RAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGIKMAVTTSGSTEMMKENWPLGAPLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAP
. . . ::: :::
XP_005 SPSVPAETLSSGIRIPVGKAPPGGWRWSGCRWPTGAY
130 140 150
>>NP_631917 (OMIM: 610603) alpha-ketoglutarate-dependent (286 aa)
initn: 339 init1: 163 opt: 377 Z-score: 459.2 bits: 92.7 E(85289): 7.7e-19
Smith-Waterman score: 377; 37.0% identity (60.9% similar) in 192 aa overlap (67-256:91-277)
40 50 60 70 80 90
pF1KE1 TRKRPRREAPGNGGHSAGPSWRHIRAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGAL
: : . ::: :...: ..: . .
NP_631 QVVRRAPEPRVIDREGVYEISLSPTGVSRVCLYPGFVDVKEADWILEQLCQDVPWKQRTG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 ARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKP-WIPVLERIRDHVSGVTGQTFNF
: .. .. :: : ::. : ::.: .:. :.: : :::. ..... ::.:::
NP_631 IREDIT---YQQPRLTAWYGE--LPYTYSRITMEPNPHWHPVLRTLKNRIEENTGHTFNS
130 140 150 160 170
160 170 180 190 200 210
pF1KE1 VLINRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFVFRHKDSRGKSPSRR-VAVV
.: : :.. : . : ::: :. :::.:::: : : .:.: .. . : :
NP_631 LLCNLYRNEKDSVDWHSDDEPSLGRCPIIASLSFGATRTFEMRKKPPPEENGDYTYVERV
180 190 200 210 220 230
220 230 240 250 260
pF1KE1 RLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLTKK
..:: ::.::.:. :.. : : .: . . :::::::: .
NP_631 KIPLDHGTLLIMEGATQADWQHRVPKEYHSREPRVNLTFRTVYPDPRGAPW
240 250 260 270 280
261 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:27:18 2016 done: Sun Nov 6 12:27:19 2016
Total Scan time: 7.400 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]