Result of FASTA (omim) for
pFN21AE1754
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1754, 131 aa
1>>>pF1KE1754 131 - 131 aa - 131 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7253+/-0.000235; mu= 12.2932+/- 0.015
mean_var=106.3595+/-21.255, 0's: 0 Z-trim(125.4): 10 B-trim: 2167 in 1/58
Lambda= 0.124362
statistics sampled from 48910 (48920) to 48910 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.872), E-opt: 0.2 (0.574), width: 16
Scan time: 5.720
The best scores are: opt bits E(85289)
NP_001120713 (OMIM: 605854) bcl-2-binding componen ( 131) 938 176.8 8.9e-45
XP_006723204 (OMIM: 605854) PREDICTED: bcl-2-bindi ( 193) 714 136.8 1.5e-32
NP_055232 (OMIM: 605854) bcl-2-binding component 3 ( 193) 714 136.8 1.5e-32
XP_011525024 (OMIM: 605854) PREDICTED: bcl-2-bindi ( 209) 714 136.8 1.6e-32
NP_001120712 (OMIM: 605854) bcl-2-binding componen ( 261) 272 57.6 1.4e-08
NP_001120714 (OMIM: 605854) bcl-2-binding componen ( 101) 261 55.2 2.7e-08
>>NP_001120713 (OMIM: 605854) bcl-2-binding component 3 (131 aa)
initn: 938 init1: 938 opt: 938 Z-score: 924.9 bits: 176.8 E(85289): 8.9e-45
Smith-Waterman score: 938; 100.0% identity (100.0% similar) in 131 aa overlap (1-131:1-131)
10 20 30 40 50 60
pF1KE1 MKFGMGSAQACPCQVPRAASTTWVPCQICGPQPSLSLAEQHLESPVPSAPGALAGGPTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKFGMGSAQACPCQVPRAASTTWVPCQICGPQPSLSLAEQHLESPVPSAPGALAGGPTQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 APGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLPLP
70 80 90 100 110 120
130
pF1KE1 RGHRAPEMEPN
:::::::::::
NP_001 RGHRAPEMEPN
130
>>XP_006723204 (OMIM: 605854) PREDICTED: bcl-2-binding c (193 aa)
initn: 714 init1: 714 opt: 714 Z-score: 705.5 bits: 136.8 E(85289): 1.5e-32
Smith-Waterman score: 714; 100.0% identity (100.0% similar) in 102 aa overlap (30-131:92-193)
10 20 30 40 50
pF1KE1 MKFGMGSAQACPCQVPRAASTTWVPCQICGPQPSLSLAEQHLESPVPSAPGALAGGPTQ
::::::::::::::::::::::::::::::
XP_006 PTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQ
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE1 AAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLPL
130 140 150 160 170 180
120 130
pF1KE1 PRGHRAPEMEPN
::::::::::::
XP_006 PRGHRAPEMEPN
190
>>NP_055232 (OMIM: 605854) bcl-2-binding component 3 iso (193 aa)
initn: 714 init1: 714 opt: 714 Z-score: 705.5 bits: 136.8 E(85289): 1.5e-32
Smith-Waterman score: 714; 100.0% identity (100.0% similar) in 102 aa overlap (30-131:92-193)
10 20 30 40 50
pF1KE1 MKFGMGSAQACPCQVPRAASTTWVPCQICGPQPSLSLAEQHLESPVPSAPGALAGGPTQ
::::::::::::::::::::::::::::::
NP_055 PTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQ
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE1 AAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLPL
130 140 150 160 170 180
120 130
pF1KE1 PRGHRAPEMEPN
::::::::::::
NP_055 PRGHRAPEMEPN
190
>>XP_011525024 (OMIM: 605854) PREDICTED: bcl-2-binding c (209 aa)
initn: 714 init1: 714 opt: 714 Z-score: 705.1 bits: 136.8 E(85289): 1.6e-32
Smith-Waterman score: 714; 100.0% identity (100.0% similar) in 102 aa overlap (30-131:108-209)
10 20 30 40 50
pF1KE1 MKFGMGSAQACPCQVPRAASTTWVPCQICGPQPSLSLAEQHLESPVPSAPGALAGGPTQ
::::::::::::::::::::::::::::::
XP_011 PTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQHLESPVPSAPGALAGGPTQ
80 90 100 110 120 130
60 70 80 90 100 110
pF1KE1 AAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLPL
140 150 160 170 180 190
120 130
pF1KE1 PRGHRAPEMEPN
::::::::::::
XP_011 PRGHRAPEMEPN
200
>>NP_001120712 (OMIM: 605854) bcl-2-binding component 3 (261 aa)
initn: 299 init1: 243 opt: 272 Z-score: 275.3 bits: 57.6 E(85289): 1.4e-08
Smith-Waterman score: 272; 65.6% identity (75.0% similar) in 64 aa overlap (1-62:1-58)
10 20 30 40 50
pF1KE1 MKFGMGSAQACPCQVPRAASTTWVPCQICGPQPSLSLAEQHL-ESPVPSAPGALAG-GPT
:::::::::::::::::::::::::::::::. :.: ..: . ::: : ::
NP_001 MKFGMGSAQACPCQVPRAASTTWVPCQICGPR------ERHGPRTPGGQLPGARRGPGPR
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 QAAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLP
. ::
NP_001 RPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWG
60 70 80 90 100 110
>>NP_001120714 (OMIM: 605854) bcl-2-binding component 3 (101 aa)
initn: 292 init1: 246 opt: 261 Z-score: 269.9 bits: 55.2 E(85289): 2.7e-08
Smith-Waterman score: 261; 59.7% identity (71.6% similar) in 67 aa overlap (1-65:1-67)
10 20 30 40 50
pF1KE1 MKFGMGSAQACPCQVPRAASTTWVPCQICGPQPSLSLAEQHLESPVPSAPG--ALAGGPT
::::::::::::::::::::::::::::: . . . ::.:: : : ::. ::
NP_001 MKFGMGSAQACPCQVPRAASTTWVPCQICETRGAAAAPPLTLEGPVQSHHGTPALTQGPQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QAAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHRPSPWRVLYNLIMGLLP
. :..
NP_001 SPRDGAQLGACTRPVDVRDSGGRPLPPPDTLASAGDFLCTM
70 80 90 100
131 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:19:05 2016 done: Sun Nov 6 13:19:06 2016
Total Scan time: 5.720 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]