Result of FASTA (omim) for
pFN21AE1738
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1738, 244 aa
1>>>pF1KE1738 244 - 244 aa - 244 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.2426+/-0.000342; mu= 20.3043+/- 0.021
mean_var=55.0669+/-11.488, 0's: 0 Z-trim(114.6): 43 B-trim: 770 in 1/49
Lambda= 0.172834
statistics sampled from 24472 (24516) to 24472 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.287), width: 16
Scan time: 6.610
The best scores are: opt bits E(85289)
NP_000130 (OMIM: 147050,147138) high affinity immu ( 244) 1573 399.8 2.2e-111
XP_011543152 (OMIM: 147050,147138) PREDICTED: high ( 244) 1573 399.8 2.2e-111
XP_005273903 (OMIM: 147050,147138) PREDICTED: high ( 251) 1573 399.8 2.2e-111
XP_016872851 (OMIM: 147050,147138) PREDICTED: high ( 204) 1158 296.3 2.7e-80
NP_001243845 (OMIM: 147050,147138) high affinity i ( 199) 864 223.0 3.1e-58
NP_076926 (OMIM: 606547) membrane-spanning 4-domai ( 220) 257 71.7 1.2e-12
XP_016873398 (OMIM: 606547) PREDICTED: membrane-sp ( 220) 257 71.7 1.2e-12
NP_683876 (OMIM: 606547) membrane-spanning 4-domai ( 239) 257 71.7 1.3e-12
NP_006129 (OMIM: 606498) membrane-spanning 4-domai ( 214) 250 69.9 4e-12
NP_060186 (OMIM: 606550) membrane-spanning 4-domai ( 267) 239 67.2 3.2e-11
XP_011543419 (OMIM: 606550) PREDICTED: membrane-sp ( 267) 239 67.2 3.2e-11
NP_113645 (OMIM: 606549) membrane-spanning 4-domai ( 250) 214 61.0 2.3e-09
XP_011543665 (OMIM: 606498) PREDICTED: membrane-sp ( 154) 205 58.6 7.6e-09
NP_067024 (OMIM: 606502) membrane-spanning 4-domai ( 240) 186 54.0 2.8e-07
NP_996822 (OMIM: 606502) membrane-spanning 4-domai ( 240) 186 54.0 2.8e-07
NP_076434 (OMIM: 606499) membrane-spanning 4-domai ( 200) 183 53.2 4.1e-07
NP_001234928 (OMIM: 606548) membrane-spanning 4-do ( 253) 173 50.8 2.8e-06
XP_005274234 (OMIM: 606548) PREDICTED: membrane-sp ( 276) 173 50.8 2.9e-06
NP_001317204 (OMIM: 606548) membrane-spanning 4-do ( 276) 173 50.8 2.9e-06
NP_690590 (OMIM: 606548) membrane-spanning 4-domai ( 178) 168 49.4 5e-06
NP_071744 (OMIM: 606548) membrane-spanning 4-domai ( 225) 168 49.5 6e-06
NP_690591 (OMIM: 606548) membrane-spanning 4-domai ( 248) 168 49.5 6.4e-06
NP_996776 (OMIM: 608403) membrane-spanning 4-domai ( 267) 151 45.3 0.00013
XP_011543291 (OMIM: 608403) PREDICTED: membrane-sp ( 290) 151 45.3 0.00014
NP_001230195 (OMIM: 606547) membrane-spanning 4-do ( 186) 149 44.7 0.00014
XP_016873614 (OMIM: 606548) PREDICTED: membrane-sp ( 145) 142 42.8 0.00039
XP_011543511 (OMIM: 606548) PREDICTED: membrane-sp ( 148) 142 42.8 0.00039
NP_690605 (OMIM: 112210,613495) B-lymphocyte antig ( 297) 136 41.6 0.0019
NP_068769 (OMIM: 112210,613495) B-lymphocyte antig ( 297) 136 41.6 0.0019
>>NP_000130 (OMIM: 147050,147138) high affinity immunogl (244 aa)
initn: 1573 init1: 1573 opt: 1573 Z-score: 2120.7 bits: 399.8 E(85289): 2.2e-111
Smith-Waterman score: 1573; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:1-244)
10 20 30 40 50 60
pF1KE1 MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSP
190 200 210 220 230 240
pF1KE1 PIDL
::::
NP_000 PIDL
>>XP_011543152 (OMIM: 147050,147138) PREDICTED: high aff (244 aa)
initn: 1573 init1: 1573 opt: 1573 Z-score: 2120.7 bits: 399.8 E(85289): 2.2e-111
Smith-Waterman score: 1573; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:1-244)
10 20 30 40 50 60
pF1KE1 MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 IVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSP
190 200 210 220 230 240
pF1KE1 PIDL
::::
XP_011 PIDL
>>XP_005273903 (OMIM: 147050,147138) PREDICTED: high aff (251 aa)
initn: 1573 init1: 1573 opt: 1573 Z-score: 2120.5 bits: 399.8 E(85289): 2.2e-111
Smith-Waterman score: 1573; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:8-251)
10 20 30 40 50
pF1KE1 MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSVNEKMDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 LSIISERRNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSIISERRNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 MASFSTEIVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASFSTEIVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELE
190 200 210 220 230 240
240
pF1KE1 DPGEMSPPIDL
:::::::::::
XP_005 DPGEMSPPIDL
250
>>XP_016872851 (OMIM: 147050,147138) PREDICTED: high aff (204 aa)
initn: 1158 init1: 1158 opt: 1158 Z-score: 1562.5 bits: 296.3 E(85289): 2.7e-80
Smith-Waterman score: 1158; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:8-186)
10 20 30 40 50
pF1KE1 MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSVNEKMDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 LSIISERRNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSIISERRNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 MASFSTEIVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELE
::::::
XP_016 MASFSTVCIFFCVGRLRFWVLMKL
190 200
>>NP_001243845 (OMIM: 147050,147138) high affinity immun (199 aa)
initn: 880 init1: 864 opt: 864 Z-score: 1166.4 bits: 223.0 E(85289): 3.1e-58
Smith-Waterman score: 1162; 81.6% identity (81.6% similar) in 244 aa overlap (1-244:1-199)
10 20 30 40 50 60
pF1KE1 MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER
:: :::::::::::::
NP_001 LG---------------------------------------------FSISGMLSIISER
70
130 140 150 160 170 180
pF1KE1 RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTE
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE1 IVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSP
140 150 160 170 180 190
pF1KE1 PIDL
::::
NP_001 PIDL
>>NP_076926 (OMIM: 606547) membrane-spanning 4-domains s (220 aa)
initn: 217 init1: 156 opt: 257 Z-score: 347.9 bits: 71.7 E(85289): 1.2e-12
Smith-Waterman score: 257; 37.0% identity (62.4% similar) in 165 aa overlap (48-203:30-187)
20 30 40 50 60 70
pF1KE1 SSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTV----LKKEQEFLGVTQILTAMICL
: : . :: : . :::.:::::.. :
NP_076 MTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSL
10 20 30 40 50
80 90 100 110 120 130
pF1KE1 CFG-TVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLG
.: :..: . :. :. : :: .::...: ::: ::: . :.. :::::::
NP_076 SMGITMMCMA---SNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLG
60 70 80 90 100 110
140 150 160 170 180
pF1KE1 ANTASSIAGGTGITILIINLKKSLAYIHIHS--CQKFFETKCFMASFSTEIVV--MMLFL
: .::. ...:: .:: :::. .: :. . ... ...: . . :.:.:
NP_076 MNITSSVLAASGI---LINTF-SLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 TILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSPPIDL
..: . ::::. :
NP_076 SVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV
180 190 200 210 220
>>XP_016873398 (OMIM: 606547) PREDICTED: membrane-spanni (220 aa)
initn: 217 init1: 156 opt: 257 Z-score: 347.9 bits: 71.7 E(85289): 1.2e-12
Smith-Waterman score: 257; 37.0% identity (62.4% similar) in 165 aa overlap (48-203:30-187)
20 30 40 50 60 70
pF1KE1 SSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTV----LKKEQEFLGVTQILTAMICL
: : . :: : . :::.:::::.. :
XP_016 MTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSL
10 20 30 40 50
80 90 100 110 120 130
pF1KE1 CFG-TVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLG
.: :..: . :. :. : :: .::...: ::: ::: . :.. :::::::
XP_016 SMGITMMCMA---SNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLG
60 70 80 90 100 110
140 150 160 170 180
pF1KE1 ANTASSIAGGTGITILIINLKKSLAYIHIHS--CQKFFETKCFMASFSTEIVV--MMLFL
: .::. ...:: .:: :::. .: :. . ... ...: . . :.:.:
XP_016 MNITSSVLAASGI---LINTF-SLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 TILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSPPIDL
..: . ::::. :
XP_016 SVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV
180 190 200 210 220
>>NP_683876 (OMIM: 606547) membrane-spanning 4-domains s (239 aa)
initn: 217 init1: 156 opt: 257 Z-score: 347.4 bits: 71.7 E(85289): 1.3e-12
Smith-Waterman score: 257; 37.0% identity (62.4% similar) in 165 aa overlap (48-203:49-206)
20 30 40 50 60 70
pF1KE1 SSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTV----LKKEQEFLGVTQILTAMICL
: : . :: : . :::.:::::.. :
NP_683 AMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSL
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE1 CFG-TVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLG
.: :..: . :. :. : :: .::...: ::: ::: . :.. :::::::
NP_683 SMGITMMCMA---SNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLG
80 90 100 110 120 130
140 150 160 170 180
pF1KE1 ANTASSIAGGTGITILIINLKKSLAYIHIHS--CQKFFETKCFMASFSTEIVV--MMLFL
: .::. ...:: .:: :::. .: :. . ... ...: . . :.:.:
NP_683 MNITSSVLAASGI---LINTF-SLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLL
140 150 160 170 180 190
190 200 210 220 230 240
pF1KE1 TILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSPPIDL
..: . ::::. :
NP_683 SVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV
200 210 220 230
>>NP_006129 (OMIM: 606498) membrane-spanning 4-domains s (214 aa)
initn: 187 init1: 152 opt: 250 Z-score: 338.6 bits: 69.9 E(85289): 4e-12
Smith-Waterman score: 250; 29.3% identity (61.4% similar) in 184 aa overlap (27-204:23-198)
10 20 30 40 50 60
pF1KE1 MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF
: .:.:.... .:: . : . .
NP_006 MASHEVDNAELGSASAHGTPGSEAGPEELNTSVYQPIDGSPDYQ------KAKLQV
10 20 30 40 50
70 80 90 100 110
pF1KE1 LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFS-SFKAGYPFWGAIFFSISGMLSIISE
::. :::.: . : .:. . :. :.. .: .: .:::.:::.:: :: ::...
NP_006 LGAIQILNAAMILALGVFLGSLQYPYHFQKHFFFFTFYTGYPIWGAVFFCSSGTLSVVAG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 RRNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETK--C-FMAS
. . ...:.: : ::. . .: ..: .:. .. ..::.. :. : .:.:
NP_006 IKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQ--SLRSCHSSSESPDLCNYMGS
120 130 140 150 160
180 190 200 210 220 230
pF1KE1 FSTEIVVMMLFLTILGLGSAVSLTI--CGAGEELKGNKVPEDRVYEELNIYSATYSELED
.:. .: ..:.::.: : ..: :.:
NP_006 ISNGMVSLLLILTLLELCVTISTIAMWCNANCCNSREEISSPPNSV
170 180 190 200 210
>>NP_060186 (OMIM: 606550) membrane-spanning 4-domains s (267 aa)
initn: 197 init1: 143 opt: 239 Z-score: 322.5 bits: 67.2 E(85289): 3.2e-11
Smith-Waterman score: 239; 34.5% identity (69.1% similar) in 110 aa overlap (44-152:74-183)
20 30 40 50 60 70
pF1KE1 PQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICL
.: . : . .:.: . ::: ::..... .
NP_060 QGAQRAQPYGITSPGIFASSQPGQGNIQMINPSVGTAVMNFKEEAKALGVIQIMVGLMHI
50 60 70 80 90 100
80 90 100 110 120 130
pF1KE1 CFGTVVCSV-LDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLG
:: :.: . ... .. : .. .::::::.. : ::: ::. . .. . ::.::::
NP_060 GFGIVLCLISFSFREVLGFASTAVIGGYPFWGGLSFIISGSLSVSASKELSRCLVKGSLG
110 120 130 140 150 160
140 150 160 170 180 190
pF1KE1 ANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTEIVVMMLFLTILG
: .::: . :. .:....
NP_060 MNIVSSILAFIGVILLLVDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHF
170 180 190 200 210 220
244 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:33:10 2016 done: Sun Nov 6 21:33:11 2016
Total Scan time: 6.610 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]