Result of FASTA (omim) for
pFN21AE1734
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1734, 241 aa
1>>>pF1KE1734 241 - 241 aa - 241 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9047+/-0.000296; mu= 16.6747+/- 0.018
mean_var=64.4363+/-13.030, 0's: 0 Z-trim(117.4): 40 B-trim: 38 in 1/53
Lambda= 0.159775
statistics sampled from 29402 (29443) to 29402 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.345), width: 16
Scan time: 6.320
The best scores are: opt bits E(85289)
NP_004823 (OMIM: 605482) glutathione S-transferase ( 241) 1627 383.2 2.2e-106
NP_001177932 (OMIM: 605482) glutathione S-transfer ( 213) 1440 340.0 1.9e-93
NP_899062 (OMIM: 612314) glutathione S-transferase ( 243) 1097 261.0 1.3e-69
XP_011537572 (OMIM: 612314) PREDICTED: glutathione ( 243) 1097 261.0 1.3e-69
NP_001177943 (OMIM: 612314) glutathione S-transfer ( 215) 940 224.8 9.5e-59
NP_001177931 (OMIM: 605482) glutathione S-transfer ( 208) 835 200.6 1.8e-51
XP_011537573 (OMIM: 612314) PREDICTED: glutathione ( 166) 723 174.7 8.8e-44
XP_011537574 (OMIM: 612314) PREDICTED: glutathione ( 166) 723 174.7 8.8e-44
XP_006717687 (OMIM: 612314) PREDICTED: glutathione ( 183) 716 173.1 2.9e-43
NP_001177942 (OMIM: 612314) glutathione S-transfer ( 209) 668 162.1 6.9e-40
XP_011537575 (OMIM: 612314) PREDICTED: glutathione ( 149) 665 161.3 8.6e-40
XP_016871159 (OMIM: 612314) PREDICTED: glutathione ( 132) 664 161.0 9.2e-40
XP_016871160 (OMIM: 612314) PREDICTED: glutathione ( 132) 664 161.0 9.2e-40
NP_001177944 (OMIM: 612314) glutathione S-transfer ( 181) 511 125.8 4.9e-29
NP_665877 (OMIM: 603758) maleylacetoacetate isomer ( 216) 216 57.9 1.6e-08
NP_039234 (OMIM: 606536) chloride intracellular ch ( 253) 162 45.5 0.0001
NP_001299589 (OMIM: 603758) maleylacetoacetate iso ( 161) 152 43.1 0.00036
NP_001242952 (OMIM: 607293,616042) chloride intrac ( 205) 139 40.1 0.0035
XP_016876732 (OMIM: 603758) PREDICTED: maleylaceto ( 177) 138 39.9 0.0036
XP_011534972 (OMIM: 603758) PREDICTED: maleylaceto ( 177) 138 39.9 0.0036
NP_001280 (OMIM: 300138,300886) chloride intracell ( 247) 139 40.2 0.004
NP_058625 (OMIM: 607293,616042) chloride intracell ( 251) 139 40.2 0.0041
XP_011512994 (OMIM: 607293,616042) PREDICTED: chlo ( 371) 139 40.3 0.0055
XP_016866442 (OMIM: 607293,616042) PREDICTED: chlo ( 410) 139 40.4 0.006
NP_001107558 (OMIM: 607293,616042) chloride intrac ( 410) 139 40.4 0.006
>>NP_004823 (OMIM: 605482) glutathione S-transferase ome (241 aa)
initn: 1627 init1: 1627 opt: 1627 Z-score: 2030.9 bits: 383.2 E(85289): 2.2e-106
Smith-Waterman score: 1627; 99.6% identity (99.6% similar) in 241 aa overlap (1-241:1-241)
10 20 30 40 50 60
pF1KE1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SKVPSLVGSFIRSQNKEDYDGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_004 SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
190 200 210 220 230 240
pF1KE1 L
:
NP_004 L
>>NP_001177932 (OMIM: 605482) glutathione S-transferase (213 aa)
initn: 1440 init1: 1440 opt: 1440 Z-score: 1798.7 bits: 340.0 E(85289): 1.9e-93
Smith-Waterman score: 1440; 99.5% identity (99.5% similar) in 213 aa overlap (29-241:1-213)
10 20 30 40 50 60
pF1KE1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
::::::::::::::::::::::::::::::::
NP_001 MRFCPFAERTRLVLKAKGIRHEVININLKNKP
10 20 30
70 80 90 100 110 120
pF1KE1 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 SKVPSLVGSFIRSQNKEDYDGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
160 170 180 190 200 210
pF1KE1 L
:
NP_001 L
>>NP_899062 (OMIM: 612314) glutathione S-transferase ome (243 aa)
initn: 1103 init1: 683 opt: 1097 Z-score: 1370.6 bits: 261.0 E(85289): 1.3e-69
Smith-Waterman score: 1097; 64.0% identity (86.8% similar) in 242 aa overlap (1-241:1-242)
10 20 30 40 50 60
pF1KE1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
:::...:.::::: :::::::: ::::::::::...::::::::: :::::.::::.:::
NP_899 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
::.. :.::: .::::.:: ::::::.:.:::::.::::.::.: ::::.: :::.::::
NP_899 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 SKVPSLVGS-FIRSQNKEDYDGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP
::: :. .. . .. .:: .:.::..:::.: ..::::::. :::::::.::
NP_899 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDY
:::::... . .::.::: :.::..::: :::: ::: ... .::::.::.::.:.: :.
NP_899 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
190 200 210 220 230 240
240
pF1KE1 GL
::
NP_899 GLC
>>XP_011537572 (OMIM: 612314) PREDICTED: glutathione S-t (243 aa)
initn: 1103 init1: 683 opt: 1097 Z-score: 1370.6 bits: 261.0 E(85289): 1.3e-69
Smith-Waterman score: 1097; 64.0% identity (86.8% similar) in 242 aa overlap (1-241:1-242)
10 20 30 40 50 60
pF1KE1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
:::...:.::::: :::::::: ::::::::::...::::::::: :::::.::::.:::
XP_011 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
::.. :.::: .::::.:: ::::::.:.:::::.::::.::.: ::::.: :::.::::
XP_011 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 SKVPSLVGS-FIRSQNKEDYDGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP
::: :. .. . .. .:: .:.::..:::.: ..::::::. :::::::.::
XP_011 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDY
:::::... . .::.::: :.::..::: :::: ::: ... .::::.::.::.:.: :.
XP_011 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
190 200 210 220 230 240
240
pF1KE1 GL
::
XP_011 GLC
>>NP_001177943 (OMIM: 612314) glutathione S-transferase (215 aa)
initn: 946 init1: 526 opt: 940 Z-score: 1175.7 bits: 224.8 E(85289): 9.5e-59
Smith-Waterman score: 940; 62.1% identity (86.0% similar) in 214 aa overlap (29-241:1-214)
10 20 30 40 50 60
pF1KE1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
:::::...::::::::: :::::.::::.:::
NP_001 MRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30
70 80 90 100 110 120
pF1KE1 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
::.. :.::: .::::.:: ::::::.:.:::::.::::.::.: ::::.: :::.::::
NP_001 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 SKVPSLVGS-FIRSQNKEDYDGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP
::: :. .. . .. .:: .:.::..:::.: ..::::::. :::::::.::
NP_001 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDY
:::::... . .::.::: :.::..::: :::: ::: ... .::::.::.::.:.: :.
NP_001 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
160 170 180 190 200 210
240
pF1KE1 GL
::
NP_001 GLC
>>NP_001177931 (OMIM: 605482) glutathione S-transferase (208 aa)
initn: 835 init1: 835 opt: 835 Z-score: 1045.1 bits: 200.6 E(85289): 1.8e-51
Smith-Waterman score: 1349; 86.3% identity (86.3% similar) in 241 aa overlap (1-241:1-208)
10 20 30 40 50 60
pF1KE1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SKVPSLVGSFIRSQNKEDYDGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW
::: ::::::::::::::::::::::::
NP_001 SKV---------------------------------LTNKKTTFFGGNSISMIDYLIWPW
130 140
190 200 210 220 230 240
pF1KE1 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
150 160 170 180 190 200
pF1KE1 L
:
NP_001 L
>>XP_011537573 (OMIM: 612314) PREDICTED: glutathione S-t (166 aa)
initn: 721 init1: 683 opt: 723 Z-score: 907.0 bits: 174.7 E(85289): 8.8e-44
Smith-Waterman score: 723; 63.7% identity (83.3% similar) in 168 aa overlap (1-167:1-166)
10 20 30 40 50 60
pF1KE1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
:::...:.::::: :::::::: ::::::::::...::::::::: :::::.::::.:::
XP_011 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
::.. :.::: .::::.:: ::::::.:.:::::.::::.::.: ::::.: :::.::::
XP_011 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 SKVPSLVGS-FIRSQNKEDYDGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP
::: :. .. . .. .:: .:.::..::: :: :. :
XP_011 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEE--DRKKRKFIPG
130 140 150 160
180 190 200 210 220 230
pF1KE1 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDY
>>XP_011537574 (OMIM: 612314) PREDICTED: glutathione S-t (166 aa)
initn: 721 init1: 683 opt: 723 Z-score: 907.0 bits: 174.7 E(85289): 8.8e-44
Smith-Waterman score: 723; 63.7% identity (83.3% similar) in 168 aa overlap (1-167:1-166)
10 20 30 40 50 60
pF1KE1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
:::...:.::::: :::::::: ::::::::::...::::::::: :::::.::::.:::
XP_011 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
::.. :.::: .::::.:: ::::::.:.:::::.::::.::.: ::::.: :::.::::
XP_011 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 SKVPSLVGS-FIRSQNKEDYDGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP
::: :. .. . .. .:: .:.::..::: :: :. :
XP_011 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEE--DRKKRKFIPG
130 140 150 160
180 190 200 210 220 230
pF1KE1 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDY
>>XP_006717687 (OMIM: 612314) PREDICTED: glutathione S-t (183 aa)
initn: 722 init1: 683 opt: 716 Z-score: 897.7 bits: 173.1 E(85289): 2.9e-43
Smith-Waterman score: 716; 65.6% identity (86.6% similar) in 157 aa overlap (1-156:1-157)
10 20 30 40 50 60
pF1KE1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
:::...:.::::: :::::::: ::::::::::...::::::::: :::::.::::.:::
XP_006 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
::.. :.::: .::::.:: ::::::.:.:::::.::::.::.: ::::.: :::.::::
XP_006 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 SKVPSLVGS-FIRSQNKEDYDGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWP
::: :. .. . .. .:: .:.::..:::.
XP_006 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEELCEPHASPAALDISHEVGPHSLCS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDY
XP_006 SHG
>>NP_001177942 (OMIM: 612314) glutathione S-transferase (209 aa)
initn: 668 init1: 668 opt: 668 Z-score: 837.0 bits: 162.1 E(85289): 6.9e-40
Smith-Waterman score: 970; 60.2% identity (78.4% similar) in 241 aa overlap (1-241:1-208)
10 20 30 40 50 60
pF1KE1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
:::...:.::::: :::::::: ::::::::::...::::::::: :::::.::::.:::
NP_001 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
::.. :.::: .::::.:: ::::::.:.:::::.::::.::.: ::::.: :::.::::
NP_001 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SKVPSLVGSFIRSQNKEDYDGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW
:. .. :: ::::::. :::::::.:::
NP_001 CKI-------LEYQN--------------------------TTFFGGTCISMIDYLLWPW
130 140
190 200 210 220 230 240
pF1KE1 FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
::::... . .::.::: :.::..::: :::: ::: ... .::::.::.::.:.: :.:
NP_001 FERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDFG
150 160 170 180 190 200
pF1KE1 L
:
NP_001 LC
241 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:22:42 2016 done: Sun Nov 6 15:22:43 2016
Total Scan time: 6.320 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]