FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1723, 234 aa
  1>>>pF1KE1723 234 - 234 aa - 234 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0292+/-0.000302; mu= 16.2871+/- 0.019
 mean_var=65.1472+/-13.090, 0's: 0 Z-trim(117.0): 10  B-trim: 213 in 2/48
 Lambda= 0.158901
 statistics sampled from 28701 (28707) to 28701 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.337), width:  16
 Scan time:  6.060

The best scores are:                                      opt bits E(85289)
NP_003249 (OMIM: 188300) thymidine kinase, cytosol ( 234) 1573 368.7 4.7e-102
XP_016880481 (OMIM: 188300) PREDICTED: thymidine k ( 309) 1128 266.8   3e-71


>>NP_003249 (OMIM: 188300) thymidine kinase, cytosolic [  (234 aa)
 initn: 1573 init1: 1573 opt: 1573  Z-score: 1953.2  bits: 368.7 E(85289): 4.7e-102
Smith-Waterman score: 1573; 100.0% identity (100.0% similar) in 234 aa overlap (1-234:1-234)

               10        20        30        40        50        60
pF1KE1 MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
              130       140       150       160       170       180

              190       200       210       220       230    
pF1KE1 YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
              190       200       210       220       230    

>>XP_016880481 (OMIM: 188300) PREDICTED: thymidine kinas  (309 aa)
 initn: 1128 init1: 1128 opt: 1128  Z-score: 1400.1  bits: 266.8 E(85289): 3e-71
Smith-Waterman score: 1490; 87.6% identity (87.6% similar) in 266 aa overlap (1-233:43-308)

                                             10        20        30
pF1KE1                               MSCINLPTVLPGSPSKTRGQIQVILGPMFS
                                     ::::::::::::::::::::::::::::::
XP_016 RGLKRSAREPGAYCGTALESTRVRELPGGAMSCINLPTVLPGSPSKTRGQIQVILGPMFS
             20        30        40        50        60        70  

               40        50        60        70        80        90
pF1KE1 GKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALG
             80        90       100       110       120       130  

              100       110       120       130       140       150
pF1KE1 VAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLT
            140       150       160       170       180       190  

              160       170                                        
pF1KE1 AVCMECFREAAYTKRLGTEKEV---------------------------------EVIGG
       ::::::::::::::::::::::                                 :::::
XP_016 AVCMECFREAAYTKRLGTEKEVAPPAFPAGRRGGGMALPPSCPGPSPIPCPCGQVEVIGG
            200       210       220       230       240       250  

       180       190       200       210       220       230    
pF1KE1 ADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_016 ADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
            260       270       280       290       300         




234 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 09:47:23 2016 done: Sun Nov  6 09:47:24 2016
 Total Scan time:  6.060 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]