Result of FASTA (omim) for
pFN21AE1714
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1714, 218 aa
1>>>pF1KE1714 218 - 218 aa - 218 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0022+/-0.000369; mu= 15.3556+/- 0.023
mean_var=67.8592+/-13.420, 0's: 0 Z-trim(113.1): 56 B-trim: 0 in 0/53
Lambda= 0.155693
statistics sampled from 22196 (22252) to 22196 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.261), width: 16
Scan time: 5.990
The best scores are: opt bits E(85289)
NP_000552 (OMIM: 138350) glutathione S-transferase ( 218) 1499 345.5 4e-95
NP_000841 (OMIM: 138333) glutathione S-transferase ( 218) 1332 308.0 7.8e-84
NP_000842 (OMIM: 138385) glutathione S-transferase ( 218) 1299 300.6 1.3e-81
XP_005270841 (OMIM: 138385) PREDICTED: glutathione ( 218) 1299 300.6 1.3e-81
NP_000839 (OMIM: 138380) glutathione S-transferase ( 218) 1296 299.9 2.1e-81
XP_005270839 (OMIM: 138350) PREDICTED: glutathione ( 184) 1272 294.5 7.8e-80
NP_671489 (OMIM: 138333) glutathione S-transferase ( 195) 1161 269.6 2.6e-72
XP_016856574 (OMIM: 138333) PREDICTED: glutathione ( 254) 1162 269.9 2.7e-72
NP_001135840 (OMIM: 138380) glutathione S-transfer ( 191) 1104 256.7 1.8e-68
NP_000840 (OMIM: 138390) glutathione S-transferase ( 225) 1104 256.8 2.1e-68
NP_666533 (OMIM: 138350) glutathione S-transferase ( 181) 1050 244.6 7.9e-65
XP_016856576 (OMIM: 138333) PREDICTED: glutathione ( 177) 942 220.3 1.6e-57
XP_016856575 (OMIM: 138333) PREDICTED: glutathione ( 213) 772 182.2 5.6e-46
XP_005270842 (OMIM: 138385) PREDICTED: glutathione ( 114) 632 150.6 1e-36
XP_016856577 (OMIM: 138333) PREDICTED: glutathione ( 150) 476 115.6 4.4e-26
NP_000843 (OMIM: 134660) glutathione S-transferase ( 210) 327 82.2 6.8e-16
NP_055300 (OMIM: 602598) hematopoietic prostagland ( 199) 264 68.1 1.2e-11
NP_000837 (OMIM: 138360) glutathione S-transferase ( 222) 209 55.8 6.8e-08
XP_011512834 (OMIM: 138360) PREDICTED: glutathione ( 222) 209 55.8 6.8e-08
NP_714543 (OMIM: 607605) glutathione S-transferase ( 222) 204 54.6 1.5e-07
NP_000838 (OMIM: 605449) glutathione S-transferase ( 222) 203 54.4 1.7e-07
NP_665683 (OMIM: 138359) glutathione S-transferase ( 222) 195 52.6 6e-07
XP_005249091 (OMIM: 138359) PREDICTED: glutathione ( 225) 175 48.1 1.4e-05
NP_001503 (OMIM: 605450) glutathione S-transferase ( 222) 173 47.7 1.8e-05
XP_005249092 (OMIM: 605450) PREDICTED: glutathione ( 222) 173 47.7 1.8e-05
XP_005262989 (OMIM: 602598) PREDICTED: hematopoiet ( 168) 171 47.1 2e-05
XP_011512836 (OMIM: 605450) PREDICTED: glutathione ( 185) 170 46.9 2.5e-05
XP_011512837 (OMIM: 605450) PREDICTED: glutathione ( 185) 170 46.9 2.5e-05
XP_016866283 (OMIM: 605449) PREDICTED: glutathione ( 172) 165 45.8 5.2e-05
XP_006715135 (OMIM: 605449) PREDICTED: glutathione ( 172) 165 45.8 5.2e-05
>>NP_000552 (OMIM: 138350) glutathione S-transferase Mu (218 aa)
initn: 1499 init1: 1499 opt: 1499 Z-score: 1828.8 bits: 345.5 E(85289): 4e-95
Smith-Waterman score: 1499; 100.0% identity (100.0% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
::::::::::::::::::::::::::::::::::::::
NP_000 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
190 200 210
>>NP_000841 (OMIM: 138333) glutathione S-transferase Mu (218 aa)
initn: 1332 init1: 1332 opt: 1332 Z-score: 1626.1 bits: 308.0 E(85289): 7.8e-84
Smith-Waterman score: 1332; 86.7% identity (95.9% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
: : ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
:::::::::::::::::::::::::::::::::::::::::::.:: ::. .::.:.:
NP_000 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
:::::.:::::: .. .:.::::::::.:.::::::::.::::::::::::.:::::::
NP_000 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
:::::::::::::::::::::::::.:.....::::::
NP_000 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
190 200 210
>>NP_000842 (OMIM: 138385) glutathione S-transferase Mu (218 aa)
initn: 1269 init1: 1269 opt: 1299 Z-score: 1586.0 bits: 300.6 E(85289): 1.3e-81
Smith-Waterman score: 1299; 87.6% identity (95.4% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
::: :::::::::::::::::::::::: :::::.:::::::::::::::::::::::::
NP_000 MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
::::::::::::::::: :::::::::::::::::::::::::.:::::.: .::.:.:
NP_000 PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
::::::::::::::::::::::::::::::.::::::::.:::::..::::::::::: :
NP_000 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
:::::::::::.:::::::::.:: .:.: :.:..:
NP_000 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
190 200 210
>>XP_005270841 (OMIM: 138385) PREDICTED: glutathione S-t (218 aa)
initn: 1269 init1: 1269 opt: 1299 Z-score: 1586.0 bits: 300.6 E(85289): 1.3e-81
Smith-Waterman score: 1299; 87.6% identity (95.4% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
::: :::::::::::::::::::::::: :::::.:::::::::::::::::::::::::
XP_005 MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
::::::::::::::::: :::::::::::::::::::::::::.:::::.: .::.:.:
XP_005 PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
::::::::::::::::::::::::::::::.::::::::.:::::..::::::::::: :
XP_005 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
:::::::::::.:::::::::.:: .:.: :.:..:
XP_005 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
190 200 210
>>NP_000839 (OMIM: 138380) glutathione S-transferase Mu (218 aa)
initn: 1296 init1: 1296 opt: 1296 Z-score: 1582.4 bits: 299.9 E(85289): 2.1e-81
Smith-Waterman score: 1296; 84.4% identity (95.9% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KE1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
::: ::::.::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
::::::.:::::::::: :::::::::::.:.:.:: :::::: ::..:::. .::.:.:
NP_000 PYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
:::::.::. ::: :::::.::::.::: :.:::::::..::::. ...:::.:::::::
NP_000 EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
:::::::::::::::::::::::::::::.::::::::
NP_000 LKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
190 200 210
>>XP_005270839 (OMIM: 138350) PREDICTED: glutathione S-t (184 aa)
initn: 1272 init1: 1272 opt: 1272 Z-score: 1554.3 bits: 294.5 E(85289): 7.8e-80
Smith-Waterman score: 1272; 100.0% identity (100.0% similar) in 184 aa overlap (35-218:1-184)
10 20 30 40 50 60
pF1KE1 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI
::::::::::::::::::::::::::::::
XP_005 MGDAPDYDRSQWLNEKFKLGLDFPNLPYLI
10 20 30
70 80 90 100 110 120
pF1KE1 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDF
100 110 120 130 140 150
190 200 210
pF1KE1 ISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
::::::::::::::::::::::::::::::::::
XP_005 ISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
160 170 180
>>NP_671489 (OMIM: 138333) glutathione S-transferase Mu (195 aa)
initn: 1161 init1: 1161 opt: 1161 Z-score: 1419.2 bits: 269.6 E(85289): 2.6e-72
Smith-Waterman score: 1161; 87.8% identity (95.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
: : ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
:::::::::::::::::::::::::::::::::::::::::::.:: ::. .::.:.:
NP_671 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
:::::.:::::: .. .:.::::::::.:.::::::::.::::::::::::.:::::::
NP_671 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
:::::::::
NP_671 LKDFISRFEVSCGIM
190
>>XP_016856574 (OMIM: 138333) PREDICTED: glutathione S-t (254 aa)
initn: 1161 init1: 1161 opt: 1162 Z-score: 1418.8 bits: 269.9 E(85289): 2.7e-72
Smith-Waterman score: 1162; 82.8% identity (91.7% similar) in 204 aa overlap (1-204:1-204)
10 20 30 40 50 60
pF1KE1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
: : ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
:::::::::::::::::::::::::::::::::::::::::::.:: ::. .::.:.:
XP_016 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
:::::.:::::: .. .:.::::::::.:.::::::::.::::::::::::.:::::::
XP_016 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
::::::::: . :.:. .:
XP_016 LKDFISRFECSKCSPCEMSSTLILLLFTDLLLCMRQGVRHSGSCIDDCPILEMSAVRGLQ
190 200 210 220 230 240
>>NP_001135840 (OMIM: 138380) glutathione S-transferase (191 aa)
initn: 1104 init1: 1104 opt: 1104 Z-score: 1350.1 bits: 256.7 E(85289): 1.8e-68
Smith-Waterman score: 1104; 82.5% identity (95.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
::: ::::.::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
::::::.:::::::::: :::::::::::.:.:.:: :::::: ::..:::. .::.:.:
NP_001 PYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
:::::.::. ::: :::::.::::.::: :.:::::::..::::. ...:::.:::::::
NP_001 EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPN
130 140 150 160 170 180
190 200 210
pF1KE1 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
:::::::::
NP_001 LKDFISRFEHS
190
>>NP_000840 (OMIM: 138390) glutathione S-transferase Mu (225 aa)
initn: 1104 init1: 1104 opt: 1104 Z-score: 1349.1 bits: 256.8 E(85289): 2.1e-68
Smith-Waterman score: 1104; 73.1% identity (88.4% similar) in 216 aa overlap (3-218:7-222)
10 20 30 40 50
pF1KE1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD
:.::::::::::::::::::.::.:::::.:: :.::::::::::. :::: ::
NP_000 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICY
:::::::.:: .::::::::: :::::::.:::::::::::::.:::.:: . :: .::
NP_000 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 NPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLD
. . :::::.:::::: .:: .: :::: ::::.:.::::::.::.:: .:::.:::::
NP_000 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
130 140 150 160 170 180
180 190 200 210
pF1KE1 AFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
::::: :. :::.::::.::..:..: :. .::: ::::
NP_000 EFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
190 200 210 220
218 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:00:06 2016 done: Sun Nov 6 19:00:07 2016
Total Scan time: 5.990 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]