Result of FASTA (omim) for
pFN21AE1710
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1710, 215 aa
1>>>pF1KE1710 215 - 215 aa - 215 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4061+/-0.000361; mu= 1.6647+/- 0.023
mean_var=224.3298+/-44.516, 0's: 0 Z-trim(120.5): 30 B-trim: 0 in 0/58
Lambda= 0.085631
statistics sampled from 35848 (35879) to 35848 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.421), width: 16
Scan time: 6.810
The best scores are: opt bits E(85289)
NP_005316 (OMIM: 142709) histone H1.1 [Homo sapien ( 215) 1303 172.8 3.9e-43
NP_005312 (OMIM: 142220) histone H1.4 [Homo sapien ( 219) 877 120.1 2.7e-27
NP_005311 (OMIM: 142210) histone H1.3 [Homo sapien ( 221) 827 114.0 2e-25
NP_005313 (OMIM: 142711) histone H1.5 [Homo sapien ( 226) 823 113.5 2.8e-25
NP_005310 (OMIM: 142710) histone H1.2 [Homo sapien ( 213) 799 110.5 2.1e-24
NP_005314 (OMIM: 142712) histone H1t [Homo sapiens ( 207) 558 80.7 1.9e-15
NP_005309 (OMIM: 142708) histone H1.0 [Homo sapien ( 194) 372 57.7 1.5e-08
NP_006017 (OMIM: 602785) histone H1x [Homo sapiens ( 213) 322 51.6 1.2e-06
>>NP_005316 (OMIM: 142709) histone H1.1 [Homo sapiens] (215 aa)
initn: 1303 init1: 1303 opt: 1303 Z-score: 895.5 bits: 172.8 E(85289): 3.9e-43
Smith-Waterman score: 1303; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215)
10 20 30 40 50 60
pF1KE1 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 PGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKV
130 140 150 160 170 180
190 200 210
pF1KE1 AKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
:::::::::::::::::::::::::::::::::::
NP_005 AKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
190 200 210
>>NP_005312 (OMIM: 142220) histone H1.4 [Homo sapiens] (219 aa)
initn: 732 init1: 540 opt: 877 Z-score: 610.9 bits: 120.1 E(85289): 2.7e-27
Smith-Waterman score: 877; 70.7% identity (86.0% similar) in 222 aa overlap (1-215:1-219)
10 20 30 40 50 60
pF1KE1 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
::::.: :::: : :: . :::.: .:.:.:.: .:: :::::..:...::::.::
NP_005 MSETAPAAPAAPAPAEKTPVKKKARK---SAGAAKRKASGPPVSELITKAVAASKERSGV
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
::::::::::::::::::::::::::.:::::::::::::::::::::::::::.: :.:
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
60 70 80 90 100 110
130 140 150 160 170
pF1KE1 PGASKV--ATKTKATGASKKLKKATGAS--KKSVK-TPKKAKKPAATR--KSSKNPKKPK
: :.:. : : .::.:: ::::::. :::.: ::::::::::. :..:.::: :
NP_005 PKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAK
120 130 140 150 160 170
180 190 200 210
pF1KE1 TVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
..::::. ::::::::::::::: ...:::.::::::: :::
NP_005 AAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
180 190 200 210
>>NP_005311 (OMIM: 142210) histone H1.3 [Homo sapiens] (221 aa)
initn: 501 init1: 501 opt: 827 Z-score: 577.5 bits: 114.0 E(85289): 2e-25
Smith-Waterman score: 827; 67.7% identity (83.0% similar) in 223 aa overlap (1-215:1-221)
10 20 30 40 50 60
pF1KE1 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
::::.: ::. : :: . ::::: .:.:.:.: .:: :::::..:...::::.::
NP_005 MSETAPLAPTIPAPAEKTPVKKKAKKA--GATAGKRKASGPPVSELITKAVAASKERSGV
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
::::::::::::::::::::::::::.:::::::::::::::::::::::::::.: : :
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGK
60 70 80 90 100 110
130 140 150 160 170
pF1KE1 PGASKV--ATKTKATGASKKLKKATGAS--KKSVK-TPKKAKKPAA---TRKSSKNPKKP
: :.:. : : .::.:: ::..::. :::.: ::::.::::. :.: .:. ::
NP_005 PKAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKV
120 130 140 150 160 170
180 190 200 210
pF1KE1 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
:: .:::.::::::::: :::::: . :::..: ::::::::
NP_005 KTPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
180 190 200 210 220
>>NP_005313 (OMIM: 142711) histone H1.5 [Homo sapiens] (226 aa)
initn: 735 init1: 554 opt: 823 Z-score: 574.7 bits: 113.5 E(85289): 2.8e-25
Smith-Waterman score: 823; 66.8% identity (83.2% similar) in 220 aa overlap (1-214:1-220)
10 20 30 40 50 60
pF1KE1 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
::::.: :. : :: : ::: : : .:.:.:.: .:: :::::..:...::::.:.
NP_005 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
:::::::::::.::::::::::::::.:::::::::::::::::::::::::::.: :.:
NP_005 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 PGASKV--ATKTKATGAS-KKLKKATGASKKSVKTPKKAKKPAAT--RKSSKNPKKPKTV
: :.:. : : .::. :: :::.::.: :::::::::::. .: .:.::: :..
NP_005 PKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAA
130 140 150 160 170 180
180 190 200 210
pF1KE1 -KPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
::::..::::: ::::::::: ...:::.:::: : ::
NP_005 AKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
190 200 210 220
>>NP_005310 (OMIM: 142710) histone H1.2 [Homo sapiens] (213 aa)
initn: 585 init1: 511 opt: 799 Z-score: 559.0 bits: 110.5 E(85289): 2.1e-24
Smith-Waterman score: 799; 67.7% identity (83.4% similar) in 223 aa overlap (1-215:1-213)
10 20 30 40 50 60
pF1KE1 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
::::.: ::::. :: . ::: :: :... .: .:: :::::..:...::::.::
NP_005 MSETAPAAPAAAPPAEKAPVKKKA---AKKAGGTPRKASGPPVSELITKAVAASKERSGV
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
::::::::::::::::::::::::::.:::::::::::::::::::::::::::.: :.:
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
60 70 80 90 100 110
130 140 150 160 170
pF1KE1 PGASKVA-TKTKA-TGASKKLKKATGAS--KKSVK-TPKKAKKPAA---TRKSSKNPKKP
: ..:.. :: : .::.:: :::.:.. :::.: :::::::::: :.: .:.:::
NP_005 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA
120 130 140 150 160 170
180 190 200 210
pF1KE1 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
:..::::.::: :: :::::::: ::..::::::::::
NP_005 KVAKPKKAAKSAAK--AVKPKAAK-----PKVVKPKKAAPKKK
180 190 200 210
>>NP_005314 (OMIM: 142712) histone H1t [Homo sapiens] (207 aa)
initn: 529 init1: 355 opt: 558 Z-score: 398.3 bits: 80.7 E(85289): 1.9e-15
Smith-Waterman score: 558; 53.1% identity (73.2% similar) in 213 aa overlap (1-209:1-207)
10 20 30 40 50
pF1KE1 MSETVPPAPAAS--AAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERG
:::::: : :.. :: :: . :...::: .::.: : . :::.::..: : :.::
NP_005 MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVP-NLSVSKLITEALSVSQERV
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 GVSLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVE
:.::.::::::::::::::::::::::..::::.:: ::::.::::::::::.::.
NP_005 GMSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 TKPGASK-VATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATR-KSSKNPKKPKTVK
:. :.: :..::: :. : : :..:: :.:::: :: :. .. .: : .:
NP_005 TRSKAKKSVSAKTKKLVLSRDSK-----SPKTAKTNKRAKKPRATTPKTVRSGRKAKGAK
120 130 140 150 160 170
180 190 200 210
pF1KE1 PKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
:. :::.::.: : : .. . .. . : ::
NP_005 GKQQQKSPVKARASKSKLTQHHEVNVRKATSKK
180 190 200
>>NP_005309 (OMIM: 142708) histone H1.0 [Homo sapiens] (194 aa)
initn: 268 init1: 268 opt: 372 Z-score: 274.4 bits: 57.7 E(85289): 1.5e-08
Smith-Waterman score: 372; 47.1% identity (66.5% similar) in 191 aa overlap (24-203:10-194)
10 20 30 40 50 60
pF1KE1 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
: :: : : ::::. :. :..:: : .. :.:.:
NP_005 MTENSTSAPAAKP-KRAKASKKSTDHPKYSDMIVAAIQAEKNRAGS
10 20 30 40
70 80 90 100 110
pF1KE1 SLAALKKALAAAGYDVEKN-NSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKK---ASS
: ...: . . : : .: .:.:::.:: ::. :.: ::::.::::::.: :. .:
NP_005 SRQSIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 V---ETKPGASKVATKTKATGASKKLKKATGASKKSVKTP-KKAKKPAATRKSSKNPKKP
: .:: .:::: ::. .: .:: .:: :: ::::: :. . :. :::
NP_005 VAFKKTKKEIKKVATPKKASKPKKAASKAP--TKKPKATPVKKAKKKLAA--TPKKAKKP
110 120 130 140 150 160
180 190 200 210
pF1KE1 KTVKPKKV-AKSPAKAKAVKPKAAKA--RVTKPKTAKPKKAAPKKK
:::: : : :..: ::: ::::: .. :. : :
NP_005 KTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
170 180 190
>>NP_006017 (OMIM: 602785) histone H1x [Homo sapiens] (213 aa)
initn: 231 init1: 180 opt: 322 Z-score: 240.5 bits: 51.6 E(85289): 1.2e-06
Smith-Waterman score: 322; 38.1% identity (61.4% similar) in 215 aa overlap (1-209:5-213)
10 20 30 40 50
pF1KE1 MSETVPPAPAASAAPEKPLAGKKAK-KPAKAAAASKKKPAGPSVSELIVQAASSSK
. :..: . : . : . :: .: .:.: :::: . :.:.:..
NP_006 MSVELEEALPVTTAEGMAKKVTKAGGSAALSPSKKRKNSKKKNQPGKYSQLVVETIRRLG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 ERGGVSLAAL-KKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLN-KK
::.: ::: . .: . .: ... . .: .::.::.. ::.:.:::::.:::::: ::
NP_006 ERNGSSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFKLNRKK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ASSVETKPGASKVATKTKATGASKKLKKATGA--SKKSVKTPKKAKKPAA-TRKSSKNPK
. . :: .:: . : : : : : :: :... : : ...:: ..:.. . :
NP_006 LEGGGERRGAPAAAT-APAPTAHKAKKAAPGAAGSRRADKKPARGQKPEQRSHKKGAGAK
130 140 150 160 170
180 190 200 210
pF1KE1 KPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
: : : ::.: : .: :: :::: : ::. : .:
NP_006 KDKGGKAKKTAA--AGGKKVK-KAAKPSV--PKVPKGRK
180 190 200 210
215 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 16:57:58 2016 done: Sun Nov 6 16:57:59 2016
Total Scan time: 6.810 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]