FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1691, 200 aa
  1>>>pF1KE1691 200 - 200 aa - 200 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.6127+/-0.000303; mu= 17.8382+/- 0.019
 mean_var=64.3395+/-12.821, 0's: 0 Z-trim(117.9): 23  B-trim: 2474 in 2/56
 Lambda= 0.159895
 statistics sampled from 30387 (30410) to 30387 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.357), width:  16
 Scan time:  6.520

The best scores are:                                      opt bits E(85289)
NP_742150 (OMIM: 607401) interferon lambda-2 [Homo ( 200) 1352 319.7 1.9e-87
XP_005258822 (OMIM: 607402,609532) PREDICTED: inte ( 200) 1294 306.4   2e-83
NP_742151 (OMIM: 607402,609532) interferon lambda- ( 196) 1268 300.4 1.3e-81
NP_742152 (OMIM: 607403) interferon lambda-1 precu ( 200)  884 211.8 6.1e-55
NP_001263183 (OMIM: 615090) interferon lambda-4 pr ( 179)  144 41.0  0.0014


>>NP_742150 (OMIM: 607401) interferon lambda-2 [Homo sap  (200 aa)
 initn: 1352 init1: 1352 opt: 1352  Z-score: 1690.9  bits: 319.7 E(85289): 1.9e-87
Smith-Waterman score: 1352; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200)

               10        20        30        40        50        60
pF1KE1 MKLDMTGDCTPVLVLMAAVLTVTGAVPVARLHGALPDARGCHIAQFKSLSPQELQAFKRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 MKLDMTGDCTPVLVLMAAVLTVTGAVPVARLHGALPDARGCHIAQFKSLSPQELQAFKRA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KDALEESLLLKDCRCHSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEATADTDPALV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 KDALEESLLLKDCRCHSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEATADTDPALV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 DVLDQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 DVLDQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTF
              130       140       150       160       170       180

              190       200
pF1KE1 NLFRLLTRDLNCVASGDLCV
       ::::::::::::::::::::
NP_742 NLFRLLTRDLNCVASGDLCV
              190       200

>>XP_005258822 (OMIM: 607402,609532) PREDICTED: interfer  (200 aa)
 initn: 1294 init1: 1294 opt: 1294  Z-score: 1618.6  bits: 306.4 E(85289): 2e-83
Smith-Waterman score: 1294; 96.0% identity (99.0% similar) in 200 aa overlap (1-200:1-200)

               10        20        30        40        50        60
pF1KE1 MKLDMTGDCTPVLVLMAAVLTVTGAVPVARLHGALPDARGCHIAQFKSLSPQELQAFKRA
       ::::::::: :::::::::::::::::::::.::::::::::::::::::::::::::::
XP_005 MKLDMTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KDALEESLLLKDCRCHSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEATADTDPALV
       :::::::::::::.:.:::::::::::::::::::.::::::::::::::::::::::: 
XP_005 KDALEESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 DVLDQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTF
       ::::::::::::::::.::::::::::::::::::::::.::::::::::::::::::::
XP_005 DVLDQPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTF
              130       140       150       160       170       180

              190       200
pF1KE1 NLFRLLTRDLNCVASGDLCV
       ::::::::::::::::::::
XP_005 NLFRLLTRDLNCVASGDLCV
              190       200

>>NP_742151 (OMIM: 607402,609532) interferon lambda-3 pr  (196 aa)
 initn: 1268 init1: 1268 opt: 1268  Z-score: 1586.3  bits: 300.4 E(85289): 1.3e-81
Smith-Waterman score: 1268; 95.9% identity (99.0% similar) in 196 aa overlap (5-200:1-196)

               10        20        30        40        50        60
pF1KE1 MKLDMTGDCTPVLVLMAAVLTVTGAVPVARLHGALPDARGCHIAQFKSLSPQELQAFKRA
           ::::: :::::::::::::::::::::.::::::::::::::::::::::::::::
NP_742     MTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRA
                   10        20        30        40        50      

               70        80        90       100       110       120
pF1KE1 KDALEESLLLKDCRCHSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEATADTDPALV
       :::::::::::::.:.:::::::::::::::::::.::::::::::::::::::::::: 
NP_742 KDALEESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALG
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KE1 DVLDQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTF
       ::::::::::::::::.::::::::::::::::::::::.::::::::::::::::::::
NP_742 DVLDQPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTF
        120       130       140       150       160       170      

              190       200
pF1KE1 NLFRLLTRDLNCVASGDLCV
       ::::::::::::::::::::
NP_742 NLFRLLTRDLNCVASGDLCV
        180       190      

>>NP_742152 (OMIM: 607403) interferon lambda-1 precursor  (200 aa)
 initn: 930 init1: 509 opt: 884  Z-score: 1107.4  bits: 211.8 E(85289): 6.1e-55
Smith-Waterman score: 884; 72.3% identity (85.9% similar) in 191 aa overlap (10-200:6-191)

               10        20        30        40        50        60
pF1KE1 MKLDMTGDCTPVLVLMAAVLTVTGAVPVARLHGALPDARGCHIAQFKSLSPQELQAFKRA
                : ::: ..  :.:.: ::...       ..::::..::::::::: .::.:
NP_742     MAAAWTVVLVTLVLGLAVAGPVPTSK---PTTTGKGCHIGRFKSLSPQELASFKKA
                   10        20           30        40        50   

               70        80        90       100       110       120
pF1KE1 KDALEESLLLKDCRCHSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEATADTDPALV
       .::::::: ::.  : : .:: .:::: :::::::.:::::::::::::::.:   ::: 
NP_742 RDALEESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAG--PALE
            60        70        80        90       100         110 

              130       140       150       160       170       180
pF1KE1 DVLDQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTF
       ::::::::::::::::..:::::::::::: ::::::::.:::::::::: :::::::::
NP_742 DVLDQPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTF
             120       130       140       150       160       170 

              190       200         
pF1KE1 NLFRLLTRDLNCVASGDLCV         
       ::::::::::. ::.:.::.         
NP_742 NLFRLLTRDLKYVADGNLCLRTSTHPEST
             180       190       200

>>NP_001263183 (OMIM: 615090) interferon lambda-4 precur  (179 aa)
 initn: 121 init1:  87 opt: 144  Z-score: 185.5  bits: 41.0 E(85289): 0.0014
Smith-Waterman score: 151; 28.1% identity (50.9% similar) in 167 aa overlap (39-200:25-179)

       10        20        30        40        50        60        
pF1KE1 CTPVLVLMAAVLTVTGAVPVARLHGALPDARGCHIAQFKSLSPQELQAFKRAKDALEESL
                                     : : .....:: :. : : :  .:  ::  
NP_001       MRPSVWAAVAAGLWVLCTVIAAAPRRCLLSHYRSLEPRTLAAAKALRDRYEEEA
                     10        20        30        40        50    

          70         80        90       100        110       120   
pF1KE1 L---LKDCRCHSRL-FPRTWDLRQLQVRERPMALEAELALT-LKVLEATADTDPALVDVL
       :    ..:  . :   ::  .  .:.   : .: .:. .:. :.  :    . : :    
NP_001 LSWGQRNCSFRPRRDPPRPSSCARLRHVARGIA-DAQAVLSGLHRSELLPGAGPIL----
           60        70        80         90       100             

           130       140       150       160       170       180   
pF1KE1 DQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTFNLF
           . :     .  ::..    : : .  ..     : ..  . .:: : .:::.:::.
NP_001 ----ELLAAAGRDVAACLE---LARPGSSRKVPGAQKRRHKPRRADSPRCRKASVVFNLL
         110       120          130       140       150       160  

           190       200
pF1KE1 RLLTRDLNCVASGDLCV
       :::: .:  .: .  :.
NP_001 RLLTWELRLAAHSGPCL
            170         




200 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 22:48:40 2016 done: Sat Nov  5 22:48:41 2016
 Total Scan time:  6.520 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]