Result of FASTA (omim) for
pFN21AE1671
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1671, 189 aa
1>>>pF1KE1671 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8798+/-0.000389; mu= 15.4770+/- 0.024
mean_var=64.4950+/-12.530, 0's: 0 Z-trim(112.1): 18 B-trim: 0 in 0/53
Lambda= 0.159702
statistics sampled from 20938 (20955) to 20938 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.246), width: 16
Scan time: 4.770
The best scores are: opt bits E(85289)
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1255 297.7 7.5e-81
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1100 262.0 4.2e-70
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1091 259.9 1.8e-69
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 1074 256.0 2.7e-68
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 1069 254.8 6e-68
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 1068 254.6 7e-68
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 1064 253.7 1.3e-67
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 1058 252.3 3.4e-67
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 1058 252.3 3.4e-67
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 1041 248.4 5.2e-66
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 1039 247.9 7.2e-66
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 1022 244.0 1.1e-64
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 1002 239.4 2.6e-63
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 715 173.3 2.2e-43
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 357 90.8 1.5e-18
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 346 88.2 8.3e-18
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 159 45.2 8.3e-05
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1255 init1: 1255 opt: 1255 Z-score: 1572.5 bits: 297.7 E(85289): 7.5e-81
Smith-Waterman score: 1255; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
:::::::::
NP_002 LQERLRRKE
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 1100 init1: 1100 opt: 1100 Z-score: 1379.5 bits: 262.0 E(85289): 4.2e-70
Smith-Waterman score: 1100; 86.8% identity (96.3% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
::: : ::::..::. ::::::::::::::::.:::.:...:::::::::::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
::::::::::::::::::::::::::::::::::::::::...::.:: ::: :::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
::..::::::.::::::::::.:.::::::::::::::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
130 140 150 160 170 180
pF1KE1 LQERLRRKE
.::::::::
NP_002 FQERLRRKE
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1091 init1: 1091 opt: 1091 Z-score: 1368.3 bits: 259.9 E(85289): 1.8e-69
Smith-Waterman score: 1091; 84.7% identity (96.3% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
:::::.:.::::::.::: :::::.: :::::.::::::.:::: ::::::::::::::
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
:::::::::::::::::::::::.::::::::::.:::.::::::.::: ::.::.::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
::..::::::.::::: ::::.:.:::::::::: :::::::::::::::::::.:.:.:
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
::.:::::.
NP_002 LQKRLRRKD
>>NP_066282 (OMIM: 147566) interferon alpha-6 precursor (189 aa)
initn: 1074 init1: 1074 opt: 1074 Z-score: 1347.2 bits: 256.0 E(85289): 2.7e-68
Smith-Waterman score: 1074; 86.2% identity (93.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
:::::.::::::::.::: ::: :::::::::..:::.:..::: ::: ::::::::::
NP_066 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
::::::::::::::.:::::::.::::::::::::::..::: ::::.::::::::::::
NP_066 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
::.:::: : ::::: ::::.:::::::::::::::::::::::::::::::::: : :
NP_066 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
:::::::::
NP_066 LQERLRRKE
>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs (190 aa)
initn: 1069 init1: 1069 opt: 1069 Z-score: 1340.9 bits: 254.8 E(85289): 6e-68
Smith-Waterman score: 1069; 84.7% identity (94.2% similar) in 189 aa overlap (1-189:2-190)
10 20 30 40 50
pF1KE1 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDF
:: ::.::::::::.::: ::::::::.::::.::::::..:::.:::: ::: :::::
NP_008 MMASPFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 GFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDL
::::::::::::::: :::::::.::: ::::.::::::.::: ::::: ::::::::::
NP_008 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 EACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSA
:::.::: : .:::::.::::.:.:::.::::::::::::::::::::::::::.:::.
NP_008 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
130 140 150 160 170 180
180
pF1KE1 NLQERLRRKE
::::::::::
NP_008 NLQERLRRKE
190
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1083 init1: 1068 opt: 1068 Z-score: 1339.7 bits: 254.6 E(85289): 7e-68
Smith-Waterman score: 1068; 83.6% identity (96.8% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
::: : ::::..::. ::::::::::::::::.:::.:...::::::: :::::::::::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
::.:::::.::::::::::::::::::::::::.::::.:...::.:: :::::::::::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
::..::::::.::::: ::::.::::::::::::::::::::::::::::::::.:.:.:
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
::.:::::.
NP_066 LQKRLRRKD
>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs (189 aa)
initn: 1064 init1: 1064 opt: 1064 Z-score: 1334.7 bits: 253.7 E(85289): 1.3e-67
Smith-Waterman score: 1064; 84.1% identity (94.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
:: ::.:::.::::.::: ::::::::.::::.::::::..:::.:::: ::: ::::::
NP_076 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
:::::::::::::: :::::::.::: ::::.::::::.::: ::::: :::::::::::
NP_076 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
::.::: : .:::::.::::.:.:::.::::::::::::::::::::::::::.:::.:
NP_076 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
:::::::::
NP_076 LQERLRRKE
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1073 init1: 1058 opt: 1058 Z-score: 1327.2 bits: 252.3 E(85289): 3.4e-67
Smith-Waterman score: 1058; 82.5% identity (96.8% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
::: : ::::..::. ::::::::::::::::.:::.:...:::::::::::::::::::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
.::::::::::::.:::::::::::::::::::.::::.:...::.:: ::::::::.::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
::..::::.:.::::: ::::.::::::::::::::::::::::::::::::::.:.:.:
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
::. ::::.
NP_067 LQKILRRKD
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1073 init1: 1058 opt: 1058 Z-score: 1327.2 bits: 252.3 E(85289): 3.4e-67
Smith-Waterman score: 1058; 82.5% identity (96.3% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE1 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
::: : ::::..::. ::::::::::::::::.:::.:....:::::::::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
.::::::::::::::::::::::::::::::::.::::.:...::.:: :::::::::::
NP_002 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
::..::::::.::::: ::::.:::::::::::: :.:::::::::::::::::.:.:.:
NP_002 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE1 LQERLRRKE
::.:::::.
NP_002 LQKRLRRKD
>>NP_000596 (OMIM: 147562) interferon alpha-2 precursor (188 aa)
initn: 1039 init1: 683 opt: 1041 Z-score: 1306.1 bits: 248.4 E(85289): 5.2e-66
Smith-Waterman score: 1041; 83.6% identity (93.1% similar) in 189 aa overlap (1-189:1-188)
10 20 30 40 50 60
pF1KE1 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
::: :.::.::.::.::: ::.::::::::::..:::::..::: ::: :::::::::::
NP_000 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
:::::: :::::::..: :::::::: :::::::::::.:::::::::::::::::::::
NP_000 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
::..: ::: .::::. ::::.:::::::::::: :::::::::::::::::::::::.:
NP_000 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
120 130 140 150 160 170
pF1KE1 LQERLRRKE
::: :: ::
NP_000 LQESLRSKE
180
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 07:34:20 2016 done: Tue Nov 8 07:34:21 2016
Total Scan time: 4.770 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]