Result of FASTA (omim) for
pFN21AE1670
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1670, 188 aa
1>>>pF1KE1670 188 - 188 aa - 188 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9714+/-0.000351; mu= 14.7037+/- 0.022
mean_var=58.0830+/-11.543, 0's: 0 Z-trim(112.7): 22 B-trim: 487 in 1/52
Lambda= 0.168287
statistics sampled from 21656 (21676) to 21656 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.254), width: 16
Scan time: 4.940
The best scores are: opt bits E(85289)
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 1227 305.9 2.4e-83
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 1043 261.3 6.9e-70
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1041 260.8 9.6e-70
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1024 256.6 1.7e-68
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 1007 252.5 2.9e-67
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 999 250.6 1.1e-66
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 994 249.4 2.6e-66
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 994 249.4 2.6e-66
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 993 249.1 3.1e-66
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 991 248.6 4.3e-66
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 988 247.9 7.2e-66
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 975 244.7 6.4e-65
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 954 239.6 2.2e-63
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 715 181.6 6.6e-46
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 345 91.8 7.7e-19
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 324 86.7 2.4e-17
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 158 46.4 3.5e-05
>>NP_000596 (OMIM: 147562) interferon alpha-2 precursor (188 aa)
initn: 1227 init1: 1227 opt: 1227 Z-score: 1617.2 bits: 305.9 E(85289): 2.4e-83
Smith-Waterman score: 1227; 100.0% identity (100.0% similar) in 188 aa overlap (1-188:1-188)
10 20 30 40 50 60
pF1KE1 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNL
130 140 150 160 170 180
pF1KE1 QESLRSKE
::::::::
NP_000 QESLRSKE
>>NP_066282 (OMIM: 147566) interferon alpha-6 precursor (189 aa)
initn: 1041 init1: 660 opt: 1043 Z-score: 1375.7 bits: 261.3 E(85289): 6.9e-70
Smith-Waterman score: 1043; 85.7% identity (91.0% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE1 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
::: ::::.::.:::::::::. :::::::::: :::.:::::::::::::::::::::
NP_066 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
:::::: ::::::::.: ::::.::: ::::::::::.:::: ::::.::::::::::::
NP_066 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
:::.: : : ::::.:::::::::::::::::: ::::::::::::::::::::: : :
NP_066 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
130 140 150 160 170 180
180
pF1KE1 LQESLRSKE
::: :: ::
NP_066 LQERLRRKE
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1039 init1: 683 opt: 1041 Z-score: 1373.1 bits: 260.8 E(85289): 9.6e-70
Smith-Waterman score: 1041; 83.6% identity (93.1% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE1 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
::: :.::.::.::.::: ::.::::::::::..:::::..::: ::: :::::::::::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
:::::: :::::::..: :::::::: :::::::::::.:::::::::::::::::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
::..: ::: .::::. ::::.:::::::::::: :::::::::::::::::::::::.:
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
180
pF1KE1 LQESLRSKE
::: :: ::
NP_002 LQERLRRKE
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1022 init1: 666 opt: 1024 Z-score: 1350.8 bits: 256.6 E(85289): 1.7e-68
Smith-Waterman score: 1024; 82.0% identity (93.1% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE1 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
::: :::..::.:::::::::.::.: :::::..::::::.::::::: ::::::::::
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
:::::: :::::::..: :::::.:: :::::::.::::::::::.::: ::.::.::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
::::: ::: :::::.:::::::.:::::::::: :::::::::::::::::::.:.:::
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
180
pF1KE1 LQESLRSKE
::. :: :.
NP_002 LQKRLRRKD
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1011 init1: 649 opt: 1007 Z-score: 1328.5 bits: 252.5 E(85289): 2.9e-67
Smith-Waterman score: 1007; 81.5% identity (93.1% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE1 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
:::.:.::.:.:::: :: ::.:::::::::::.::.:.::::: ::: :::::::::::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
::.::: :.:::::..: :::::::: ::::::.::::::...::.:: :::::::::::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
::::: ::: :::::.:::::::::::::::::: :::::::::::::::::::.:.:::
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
180
pF1KE1 LQESLRSKE
::. :: :.
NP_066 LQKRLRRKD
>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs (190 aa)
initn: 997 init1: 650 opt: 999 Z-score: 1318.0 bits: 250.6 E(85289): 1.1e-66
Smith-Waterman score: 999; 82.5% identity (89.4% similar) in 189 aa overlap (1-188:2-190)
10 20 30 40 50
pF1KE1 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDF
:: ::::.::.:::::::::.:::::.:::: .:::::::::: ::: ::: :::::
NP_008 MMASPFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 GFPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDL
::::::: ::::::: .: ::::.::::::::.:::::::::: ::::: ::::::::::
NP_008 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 EACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLST
::::.: : :::::. ::::::.:::.:::::: :::::::::::::::::::.::::
NP_008 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
130 140 150 160 170 180
180
pF1KE1 NLQESLRSKE
:::: :: ::
NP_008 NLQERLRRKE
190
>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs (189 aa)
initn: 992 init1: 650 opt: 994 Z-score: 1311.4 bits: 249.4 E(85289): 2.6e-66
Smith-Waterman score: 994; 82.0% identity (89.4% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE1 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
:: ::::..:.:::::::::.:::::.:::: .:::::::::: ::: ::: ::::::
NP_076 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
:::::: ::::::: .: ::::.::::::::.:::::::::: ::::: :::::::::::
NP_076 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
:::.: : :::::. ::::::.:::.:::::: :::::::::::::::::::.:::::
NP_076 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
130 140 150 160 170 180
180
pF1KE1 LQESLRSKE
::: :: ::
NP_076 LQERLRRKE
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 992 init1: 641 opt: 994 Z-score: 1311.4 bits: 249.4 E(85289): 2.6e-66
Smith-Waterman score: 994; 81.5% identity (91.0% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE1 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
:::.:.::.:.:::: :: ::.:::::::::::.::.:.::::: ::: :::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
:::::: :::::::..: :::::::: :::::::::::.:...::.:: ::: :::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
::::: ::: :::::. ::::::.:::::::::: :::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
130 140 150 160 170 180
180
pF1KE1 LQESLRSKE
.:: :: ::
NP_002 FQERLRRKE
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1006 init1: 647 opt: 993 Z-score: 1310.1 bits: 249.1 E(85289): 3.1e-66
Smith-Waterman score: 993; 80.4% identity (93.1% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE1 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
:::.:.::.:.:::: :: ::.:::::::::::.::.:.::::: ::: :::::::::::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
.::::: ::::::...: :::::::: ::::::.::::::...::.:: ::::::::.::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
::::: ::. :::::.:::::::::::::::::: :::::::::::::::::::.:.:::
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
180
pF1KE1 LQESLRSKE
::. :: :.
NP_067 LQKILRRKD
>>NP_002164 (OMIM: 147580) interferon alpha-16 precursor (189 aa)
initn: 989 init1: 654 opt: 991 Z-score: 1307.5 bits: 248.6 E(85289): 4.3e-66
Smith-Waterman score: 991; 81.0% identity (91.0% similar) in 189 aa overlap (1-188:1-189)
10 20 30 40 50 60
pF1KE1 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
:::.:.::.:.:::: :: ::.:::::::::::.::.:.::::: ::: :::::::.:::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
:::: : :::::::..: ..:::::: :::::::::::::::::::::: ::.:::::::
NP_002 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
::: : ::: : ::.:::::::::::::::::: ::::::::::::::::::::.:::
NP_002 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
180
pF1KE1 LQESLRSKE
::..:: :.
NP_002 LQKGLRRKD
188 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:48:47 2016 done: Sun Nov 6 15:48:48 2016
Total Scan time: 4.940 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]