Result of FASTA (omim) for
pFN21AE1656
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1656, 173 aa
1>>>pF1KE1656 173 - 173 aa - 173 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1834+/-0.000326; mu= 13.3105+/- 0.020
mean_var=90.2428+/-18.455, 0's: 0 Z-trim(117.9): 197 B-trim: 514 in 1/49
Lambda= 0.135011
statistics sampled from 29973 (30292) to 29973 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.355), width: 16
Scan time: 5.370
The best scores are: opt bits E(85289)
XP_005250821 (OMIM: 606449) PREDICTED: protein tyr ( 173) 1182 239.6 1.9e-63
XP_011515105 (OMIM: 606449) PREDICTED: protein tyr ( 173) 1182 239.6 1.9e-63
NP_116000 (OMIM: 606449) protein tyrosine phosphat ( 173) 1182 239.6 1.9e-63
XP_011515107 (OMIM: 606449) PREDICTED: protein tyr ( 173) 1182 239.6 1.9e-63
XP_006716563 (OMIM: 606449) PREDICTED: protein tyr ( 149) 962 196.7 1.3e-50
XP_011534414 (OMIM: 601585) PREDICTED: protein tyr ( 173) 962 196.8 1.5e-50
XP_016866759 (OMIM: 601585) PREDICTED: protein tyr ( 173) 962 196.8 1.5e-50
XP_016866760 (OMIM: 601585) PREDICTED: protein tyr ( 173) 962 196.8 1.5e-50
NP_003454 (OMIM: 601585) protein tyrosine phosphat ( 173) 962 196.8 1.5e-50
XP_011534413 (OMIM: 601585) PREDICTED: protein tyr ( 173) 962 196.8 1.5e-50
NP_536316 (OMIM: 601584) protein tyrosine phosphat ( 167) 927 189.9 1.6e-48
XP_016866761 (OMIM: 601585) PREDICTED: protein tyr ( 135) 763 157.9 5.8e-39
XP_016868487 (OMIM: 606449) PREDICTED: protein tyr ( 148) 761 157.6 8.1e-39
NP_009010 (OMIM: 606449) protein tyrosine phosphat ( 148) 761 157.6 8.1e-39
XP_005271288 (OMIM: 601584) PREDICTED: protein tyr ( 142) 602 126.6 1.7e-29
NP_001182029 (OMIM: 601584) protein tyrosine phosp ( 142) 602 126.6 1.7e-29
XP_016857890 (OMIM: 601584) PREDICTED: protein tyr ( 136) 600 126.2 2.1e-29
NP_001182030 (OMIM: 601584) protein tyrosine phosp ( 136) 600 126.2 2.1e-29
XP_005271289 (OMIM: 601584) PREDICTED: protein tyr ( 136) 600 126.2 2.1e-29
XP_016868488 (OMIM: 606449) PREDICTED: protein tyr ( 124) 541 114.6 5.7e-26
XP_016870738 (OMIM: 603505) PREDICTED: dual specif ( 296) 199 48.4 1.2e-05
XP_011517461 (OMIM: 603505) PREDICTED: dual specif ( 331) 199 48.4 1.3e-05
XP_016870737 (OMIM: 603505) PREDICTED: dual specif ( 390) 199 48.5 1.4e-05
XP_016870736 (OMIM: 603505) PREDICTED: dual specif ( 422) 199 48.5 1.5e-05
XP_016870735 (OMIM: 603505) PREDICTED: dual specif ( 448) 199 48.6 1.6e-05
XP_005252345 (OMIM: 603505) PREDICTED: dual specif ( 448) 199 48.6 1.6e-05
NP_003662 (OMIM: 603505) dual specificity protein ( 459) 199 48.6 1.6e-05
NP_001070649 (OMIM: 603505) dual specificity prote ( 461) 199 48.6 1.6e-05
XP_011517460 (OMIM: 603505) PREDICTED: dual specif ( 471) 199 48.6 1.6e-05
XP_016870734 (OMIM: 603505) PREDICTED: dual specif ( 479) 199 48.6 1.7e-05
XP_016870733 (OMIM: 603505) PREDICTED: dual specif ( 483) 199 48.6 1.7e-05
XP_016870732 (OMIM: 603505) PREDICTED: dual specif ( 485) 199 48.6 1.7e-05
NP_201588 (OMIM: 603505) dual specificity protein ( 498) 199 48.6 1.7e-05
XP_011517458 (OMIM: 603505) PREDICTED: dual specif ( 514) 199 48.6 1.7e-05
XP_016870731 (OMIM: 603505) PREDICTED: dual specif ( 520) 199 48.6 1.8e-05
XP_016870730 (OMIM: 603505) PREDICTED: dual specif ( 544) 199 48.7 1.8e-05
XP_011517455 (OMIM: 603505) PREDICTED: dual specif ( 552) 199 48.7 1.8e-05
XP_011517454 (OMIM: 603505) PREDICTED: dual specif ( 564) 199 48.7 1.9e-05
XP_011517453 (OMIM: 603505) PREDICTED: dual specif ( 578) 199 48.7 1.9e-05
XP_011517452 (OMIM: 603505) PREDICTED: dual specif ( 578) 199 48.7 1.9e-05
XP_011517451 (OMIM: 603505) PREDICTED: dual specif ( 585) 199 48.7 1.9e-05
XP_011517450 (OMIM: 603505) PREDICTED: dual specif ( 591) 199 48.7 1.9e-05
XP_011517449 (OMIM: 603505) PREDICTED: dual specif ( 603) 199 48.7 1.9e-05
XP_016870729 (OMIM: 603505) PREDICTED: dual specif ( 613) 199 48.7 2e-05
NP_201570 (OMIM: 603504,616958) dual specificity p ( 383) 186 46.0 8.2e-05
XP_011540648 (OMIM: 603504,616958) PREDICTED: dual ( 392) 186 46.0 8.3e-05
XP_016858136 (OMIM: 603504,616958) PREDICTED: dual ( 489) 186 46.1 9.7e-05
XP_016858135 (OMIM: 603504,616958) PREDICTED: dual ( 490) 186 46.1 9.7e-05
XP_011540647 (OMIM: 603504,616958) PREDICTED: dual ( 495) 186 46.1 9.8e-05
NP_001306140 (OMIM: 603504,616958) dual specificit ( 565) 186 46.1 0.00011
>>XP_005250821 (OMIM: 606449) PREDICTED: protein tyrosin (173 aa)
initn: 1182 init1: 1182 opt: 1182 Z-score: 1260.2 bits: 239.6 E(85289): 1.9e-63
Smith-Waterman score: 1182; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KE1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
>>XP_011515105 (OMIM: 606449) PREDICTED: protein tyrosin (173 aa)
initn: 1182 init1: 1182 opt: 1182 Z-score: 1260.2 bits: 239.6 E(85289): 1.9e-63
Smith-Waterman score: 1182; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KE1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
>>NP_116000 (OMIM: 606449) protein tyrosine phosphatase (173 aa)
initn: 1182 init1: 1182 opt: 1182 Z-score: 1260.2 bits: 239.6 E(85289): 1.9e-63
Smith-Waterman score: 1182; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KE1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
>>XP_011515107 (OMIM: 606449) PREDICTED: protein tyrosin (173 aa)
initn: 1182 init1: 1182 opt: 1182 Z-score: 1260.2 bits: 239.6 E(85289): 1.9e-63
Smith-Waterman score: 1182; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KE1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
>>XP_006716563 (OMIM: 606449) PREDICTED: protein tyrosin (149 aa)
initn: 962 init1: 962 opt: 962 Z-score: 1029.4 bits: 196.7 E(85289): 1.3e-50
Smith-Waterman score: 970; 86.1% identity (86.1% similar) in 173 aa overlap (1-173:1-149)
10 20 30 40 50 60
pF1KE1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
::::::::::: :::::::::::::::::::::::::
XP_006 MARMNRPAPVE------------------------DLKKYGATTVVRVCEVTYDKTPLEK
10 20 30
70 80 90 100 110 120
pF1KE1 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
100 110 120 130 140
>>XP_011534414 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 978 init1: 962 opt: 962 Z-score: 1028.6 bits: 196.8 E(85289): 1.5e-50
Smith-Waterman score: 962; 79.1% identity (92.4% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KE1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
::::::::::::.::.::::::::::::::. :::.:::::.::.:::::.::: : .::
XP_011 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
.:: :.:::::::::: ...:.::::::: :: : :: :.::::::::::::::::::::
XP_011 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
:.:::::::.::::::::::.::::: ::::::::.:::::: . :.. ::.
XP_011 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>XP_016866759 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 978 init1: 962 opt: 962 Z-score: 1028.6 bits: 196.8 E(85289): 1.5e-50
Smith-Waterman score: 962; 79.1% identity (92.4% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KE1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
::::::::::::.::.::::::::::::::. :::.:::::.::.:::::.::: : .::
XP_016 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
.:: :.:::::::::: ...:.::::::: :: : :: :.::::::::::::::::::::
XP_016 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
:.:::::::.::::::::::.::::: ::::::::.:::::: . :.. ::.
XP_016 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>XP_016866760 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 978 init1: 962 opt: 962 Z-score: 1028.6 bits: 196.8 E(85289): 1.5e-50
Smith-Waterman score: 962; 79.1% identity (92.4% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KE1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
::::::::::::.::.::::::::::::::. :::.:::::.::.:::::.::: : .::
XP_016 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
.:: :.:::::::::: ...:.::::::: :: : :: :.::::::::::::::::::::
XP_016 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
:.:::::::.::::::::::.::::: ::::::::.:::::: . :.. ::.
XP_016 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>NP_003454 (OMIM: 601585) protein tyrosine phosphatase (173 aa)
initn: 978 init1: 962 opt: 962 Z-score: 1028.6 bits: 196.8 E(85289): 1.5e-50
Smith-Waterman score: 962; 79.1% identity (92.4% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KE1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
::::::::::::.::.::::::::::::::. :::.:::::.::.:::::.::: : .::
NP_003 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
.:: :.:::::::::: ...:.::::::: :: : :: :.::::::::::::::::::::
NP_003 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
:.:::::::.::::::::::.::::: ::::::::.:::::: . :.. ::.
NP_003 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>XP_011534413 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 978 init1: 962 opt: 962 Z-score: 1028.6 bits: 196.8 E(85289): 1.5e-50
Smith-Waterman score: 962; 79.1% identity (92.4% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KE1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
::::::::::::.::.::::::::::::::. :::.:::::.::.:::::.::: : .::
XP_011 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
.:: :.:::::::::: ...:.::::::: :: : :: :.::::::::::::::::::::
XP_011 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
:.:::::::.::::::::::.::::: ::::::::.:::::: . :.. ::.
XP_011 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
173 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:53:06 2016 done: Sun Nov 6 15:53:07 2016
Total Scan time: 5.370 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]