Result of FASTA (ccds) for
pFN21AE1643
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1643, 158 aa
1>>>pF1KE1643 158 - 158 aa - 158 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9550+/-0.000686; mu= 13.5244+/- 0.041
mean_var=56.1974+/-11.152, 0's: 0 Z-trim(108.5): 19 B-trim: 45 in 1/53
Lambda= 0.171087
statistics sampled from 10203 (10221) to 10203 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.314), width: 16
Scan time: 1.820
The best scores are: opt bits E(32554)
CCDS42734.1 IL36A gene_id:27179|Hs108|chr2 ( 158) 1059 269.0 8.7e-73
CCDS2108.1 IL36G gene_id:56300|Hs108|chr2 ( 169) 616 159.6 7.6e-40
CCDS2110.1 IL36B gene_id:27177|Hs108|chr2 ( 157) 502 131.5 2.1e-31
CCDS62992.1 IL36G gene_id:56300|Hs108|chr2 ( 134) 481 126.3 6.7e-30
CCDS2107.1 IL37 gene_id:27178|Hs108|chr2 ( 192) 306 83.2 9.2e-17
CCDS2104.1 IL37 gene_id:27178|Hs108|chr2 ( 197) 306 83.2 9.4e-17
CCDS2103.1 IL37 gene_id:27178|Hs108|chr2 ( 218) 306 83.2 1e-16
CCDS2109.1 IL36B gene_id:27177|Hs108|chr2 ( 164) 266 73.2 7.5e-14
CCDS2111.1 IL36RN gene_id:26525|Hs108|chr2 ( 155) 245 68.0 2.6e-12
CCDS2115.1 IL1RN gene_id:3557|Hs108|chr2 ( 143) 235 65.6 1.3e-11
CCDS2113.1 IL1RN gene_id:3557|Hs108|chr2 ( 159) 235 65.6 1.5e-11
CCDS46396.1 IL1RN gene_id:3557|Hs108|chr2 ( 177) 235 65.6 1.6e-11
CCDS2114.1 IL1RN gene_id:3557|Hs108|chr2 ( 180) 235 65.6 1.6e-11
CCDS2112.1 IL1F10 gene_id:84639|Hs108|chr2 ( 152) 231 64.6 2.8e-11
>>CCDS42734.1 IL36A gene_id:27179|Hs108|chr2 (158 aa)
initn: 1059 init1: 1059 opt: 1059 Z-score: 1420.2 bits: 269.0 E(32554): 8.7e-73
Smith-Waterman score: 1059; 99.4% identity (100.0% similar) in 158 aa overlap (1-158:1-158)
10 20 30 40 50 60
pF1KE1 MEKALKIDTPQRGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MEKALKIDTPQQGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 NPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFES
70 80 90 100 110 120
130 140 150
pF1KE1 VAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF
::::::::::::::::::::::::::::::::::::::
CCDS42 VAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF
130 140 150
>>CCDS2108.1 IL36G gene_id:56300|Hs108|chr2 (169 aa)
initn: 617 init1: 561 opt: 616 Z-score: 828.8 bits: 159.6 E(32554): 7.6e-40
Smith-Waterman score: 616; 59.9% identity (87.8% similar) in 147 aa overlap (10-156:22-167)
10 20 30 40
pF1KE1 MEKALKIDTPQRGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALIS
: :.:.:.:..::.:: :.:.::::.: ..:::.:.:.
CCDS21 MRGTPGDADGGGRAVYQSMCKPITGTINDLNQQVWTLQGQNLVAVPRSDSVTPVTVAVIT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 CRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFY
:.. :.::. ::.:::::... ..::.: :::.::::::::. :::::.:::::: ::::
CCDS21 CKYPEALEQGRGDPIYLGIQNPEMCLYCEKVGEQPTLQLKEQKIMDLYGQPEPVKPFLFY
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 HSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF
....::.::.:::::: :::: ::. :.:::.::::. .: : :..
CCDS21 RAKTGRTSTLESVAFPDWFIA-SSKRDQPIILTSELGKSYNTAFELNIND
130 140 150 160
>>CCDS2110.1 IL36B gene_id:27177|Hs108|chr2 (157 aa)
initn: 504 init1: 484 opt: 502 Z-score: 677.2 bits: 131.5 E(32554): 2.1e-31
Smith-Waterman score: 502; 49.0% identity (80.0% similar) in 145 aa overlap (10-154:9-153)
10 20 30 40 50 60
pF1KE1 MEKALKIDTPQRGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRG
:. .:.: . ::::. ..:::.: . ..:::. ::.:: .: .:..:
CCDS21 MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKG
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 NPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFES
: .:::..: .:::.::.. .::::::::.::::: . . : :::.:.. : .:.:.:
CCDS21 NMVYLGIKGKDLCLFCAEIQGKPTLQLKEKNIMDLYVEKKAQKPFLFFHNKEGSTSVFQS
60 70 80 90 100 110
130 140 150
pF1KE1 VAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF
:..::::::.:. .: :..::.: : .:.:.: :
CCDS21 VSYPGWFIATSTTSGQPIFLTKERGITNNTNFYLDSVE
120 130 140 150
>>CCDS62992.1 IL36G gene_id:56300|Hs108|chr2 (134 aa)
initn: 482 init1: 426 opt: 481 Z-score: 650.3 bits: 126.3 E(32554): 6.7e-30
Smith-Waterman score: 481; 60.9% identity (87.8% similar) in 115 aa overlap (42-156:19-132)
20 30 40 50 60 70
pF1KE1 RGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNGLN
.:.:.:.:.. :.::. ::.:::::... .
CCDS62 MRGTPGDADGGGRAVYQSITVAVITCKYPEALEQGRGDPIYLGIQNPE
10 20 30 40
80 90 100 110 120 130
pF1KE1 LCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVS
.::.: :::.::::::::. :::::.:::::: ::::....::.::.:::::: :::: :
CCDS62 MCLYCEKVGEQPTLQLKEQKIMDLYGQPEPVKPFLFYRAKTGRTSTLESVAFPDWFIA-S
50 60 70 80 90 100
140 150
pF1KE1 SEGGCPLILTQELGKANTTDFGLTMLF
:. :.:::.::::. .: : :..
CCDS62 SKRDQPIILTSELGKSYNTAFELNIND
110 120 130
>>CCDS2107.1 IL37 gene_id:27178|Hs108|chr2 (192 aa)
initn: 271 init1: 105 opt: 306 Z-score: 414.4 bits: 83.2 E(32554): 9.2e-17
Smith-Waterman score: 306; 37.6% identity (67.1% similar) in 149 aa overlap (10-154:31-177)
10 20 30
pF1KE1 MEKALKIDTPQRGSIQDINHRVWVLQDQTLIAVPRKDRM
:.. ::.: .:.: ::.. .::::: :. .
CCDS21 MSGCDRRETETKGKNSFKKRLRGPKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 SP-VTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQ--PTLQLKEKDIMDLY
: . .:: : . :: :.:: ::.. ..::.: : : :.::::.. .: :
CCDS21 RPEIFFALASSLSSASAEK--GSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLA
70 80 90 100 110
100 110 120 130 140 150
pF1KE1 NQPEPVKS-FLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLT
: : .. :.::..: : . .::.: ::::: .: . . :. .:... . . .:..
CCDS21 AQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ
120 130 140 150 160 170
pF1KE1 MLF
CCDS21 PVCKAEMSPSEVSD
180 190
>>CCDS2104.1 IL37 gene_id:27178|Hs108|chr2 (197 aa)
initn: 271 init1: 105 opt: 306 Z-score: 414.3 bits: 83.2 E(32554): 9.4e-17
Smith-Waterman score: 306; 37.6% identity (67.1% similar) in 149 aa overlap (10-154:36-182)
10 20 30
pF1KE1 MEKALKIDTPQRGSIQDINHRVWVLQDQTLIAVPRKDRM
:.. ::.: .:.: ::.. .::::: :. .
CCDS21 ENSGVKMGSEDWEKDEPQCCLEGPKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 SP-VTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQ--PTLQLKEKDIMDLY
: . .:: : . :: :.:: ::.. ..::.: : : :.::::.. .: :
CCDS21 RPEIFFALASSLSSASAEK--GSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 NQPEPVKS-FLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLT
: : .. :.::..: : . .::.: ::::: .: . . :. .:... . . .:..
CCDS21 AQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ
130 140 150 160 170 180
pF1KE1 MLF
CCDS21 PVCKAEMSPSEVSD
190
>>CCDS2103.1 IL37 gene_id:27178|Hs108|chr2 (218 aa)
initn: 271 init1: 105 opt: 306 Z-score: 413.6 bits: 83.2 E(32554): 1e-16
Smith-Waterman score: 306; 37.6% identity (67.1% similar) in 149 aa overlap (10-154:57-203)
10 20 30
pF1KE1 MEKALKIDTPQRGSIQDINHRVWVLQDQTLIAVPRKDRM
:.. ::.: .:.: ::.. .::::: :. .
CCDS21 EDPAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYI
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 SP-VTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQ--PTLQLKEKDIMDLY
: . .:: : . :: :.:: ::.. ..::.: : : :.::::.. .: :
CCDS21 RPEIFFALASSLSSASAEK--GSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLA
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 NQPEPVKS-FLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLT
: : .. :.::..: : . .::.: ::::: .: . . :. .:... . . .:..
CCDS21 AQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ
150 160 170 180 190 200
pF1KE1 MLF
CCDS21 PVCKAEMSPSEVSD
210
>>CCDS2109.1 IL36B gene_id:27177|Hs108|chr2 (164 aa)
initn: 248 init1: 248 opt: 266 Z-score: 362.1 bits: 73.2 E(32554): 7.5e-14
Smith-Waterman score: 266; 44.7% identity (76.5% similar) in 85 aa overlap (10-94:9-93)
10 20 30 40 50 60
pF1KE1 MEKALKIDTPQRGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRG
:. .:.: . ::::. ..:::.: . ..:::. ::.:: .: .:..:
CCDS21 MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKG
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 NPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFES
: .:::..: .:::.::.. .:::::: . .:
CCDS21 NMVYLGIKGKDLCLFCAEIQGKPTLQLKLQGSQDNIGKDTCWKLVGIHTCINLDVRESCF
60 70 80 90 100 110
130 140 150
pF1KE1 VAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF
CCDS21 MGTLDQWGIGVGRKKWKSSFQHHHLRKKDKDFSSMRTNIGMPGRM
120 130 140 150 160
>>CCDS2111.1 IL36RN gene_id:26525|Hs108|chr2 (155 aa)
initn: 224 init1: 192 opt: 245 Z-score: 334.5 bits: 68.0 E(32554): 2.6e-12
Smith-Waterman score: 245; 44.8% identity (68.8% similar) in 96 aa overlap (61-152:55-149)
40 50 60 70 80 90
pF1KE1 IAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEK
.:. ::..: . :: :. ::..::: :.
CCDS21 QLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILGVQGGSQCLSCG-VGQEPTLTLEPV
30 40 50 60 70 80
100 110 120 130 140
pF1KE1 DIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQ--ELGKAN
.::.:: . ::: ::. . : .:.:::.:.::::. . :. :. ::: : : :
CCDS21 NIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWN
90 100 110 120 130 140
150
pF1KE1 T--TDFGLTMLF
. :::
CCDS21 APITDFYFQQCD
150
>>CCDS2115.1 IL1RN gene_id:3557|Hs108|chr2 (143 aa)
initn: 222 init1: 222 opt: 235 Z-score: 321.7 bits: 65.6 E(32554): 1.3e-11
Smith-Waterman score: 235; 33.1% identity (63.8% similar) in 127 aa overlap (15-141:6-125)
10 20 30 40 50 60
pF1KE1 MEKALKIDTPQRGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRG
: :.:.... :... :.: .. .. : : .:
CCDS21 MQAFRIWDVNQKTFYLRNNQLVA----GYLQGPNVNLEEKIDVVPIEP---
10 20 30 40
70 80 90 100 110 120
pF1KE1 NPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFES
. ..::..: ..:: :.: ::. :::. .: :: .. . : : : .:.:: ...:::
CCDS21 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
50 60 70 80 90 100
130 140 150
pF1KE1 VAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF
.: ::::. .. :. :. ::
CCDS21 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
110 120 130 140
158 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 11:01:18 2016 done: Sun Nov 6 11:01:18 2016
Total Scan time: 1.820 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]