Result of FASTA (omim) for
pFN21AE1639
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1639, 152 aa
1>>>pF1KE1639 152 - 152 aa - 152 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7217+/-0.000326; mu= 14.5191+/- 0.020
mean_var=55.5197+/-11.246, 0's: 0 Z-trim(115.0): 41 B-trim: 146 in 1/48
Lambda= 0.172128
statistics sampled from 25124 (25165) to 25124 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.295), width: 16
Scan time: 5.020
The best scores are: opt bits E(85289)
NP_002659 (OMIM: 300112) proteolipid protein 2 [Ho ( 152) 1020 260.9 5.7e-70
NP_612469 (OMIM: 607888) CKLF-like MARVEL transmem ( 156) 255 70.9 9e-13
XP_016876442 (OMIM: 607888) PREDICTED: CKLF-like M ( 156) 255 70.9 9e-13
XP_016876443 (OMIM: 607888) PREDICTED: CKLF-like M ( 156) 255 70.9 9e-13
NP_853531 (OMIM: 607886) CKLF-like MARVEL transmem ( 182) 217 61.5 7.1e-10
XP_006721194 (OMIM: 607886) PREDICTED: CKLF-like M ( 182) 217 61.5 7.1e-10
NP_653202 (OMIM: 607886) CKLF-like MARVEL transmem ( 182) 217 61.5 7.1e-10
NP_612419 (OMIM: 607890) CKLF-like MARVEL transmem ( 175) 192 55.3 5.1e-08
NP_852662 (OMIM: 607887) CKLF-like MARVEL transmem ( 208) 175 51.1 1.1e-06
XP_016878443 (OMIM: 607887) PREDICTED: CKLF-like M ( 221) 175 51.2 1.1e-06
NP_848933 (OMIM: 607887) CKLF-like MARVEL transmem ( 234) 175 51.2 1.2e-06
XP_016861135 (OMIM: 607890) PREDICTED: CKLF-like M ( 179) 172 50.3 1.6e-06
XP_011531621 (OMIM: 607890) PREDICTED: CKLF-like M ( 151) 171 50.1 1.7e-06
NP_443725 (OMIM: 607884) CKLF-like MARVEL transmem ( 286) 170 50.0 3.3e-06
NP_001032365 (OMIM: 607888) CKLF-like MARVEL trans ( 125) 161 47.5 8e-06
XP_011521184 (OMIM: 607887) PREDICTED: CKLF-like M ( 179) 159 47.1 1.5e-05
NP_001275675 (OMIM: 607888) CKLF-like MARVEL trans ( 223) 159 47.2 1.8e-05
NP_851786 (OMIM: 607884) CKLF-like MARVEL transmem ( 169) 156 46.4 2.4e-05
NP_851785 (OMIM: 607884) CKLF-like MARVEL transmem ( 231) 147 44.2 0.00015
NP_851787 (OMIM: 607884) CKLF-like MARVEL transmem ( 114) 133 40.5 0.00092
NP_058647 (OMIM: 616074) chemokine-like factor iso ( 152) 131 40.1 0.0016
NP_653274 (OMIM: 607885) CKLF-like MARVEL transmem ( 248) 133 40.8 0.0017
>>NP_002659 (OMIM: 300112) proteolipid protein 2 [Homo s (152 aa)
initn: 1020 init1: 1020 opt: 1020 Z-score: 1377.1 bits: 260.9 E(85289): 5.7e-70
Smith-Waterman score: 1020; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KE1 MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFSASTPGYSSLSVIEMILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFSASTPGYSSLSVIEMILA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSIVVLVERGNHSKIVAGVLGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSIVVLVERGNHSKIVAGVLGLI
70 80 90 100 110 120
130 140 150
pF1KE1 ATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
::::::::::::::::::::::::::::::::
NP_002 ATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
130 140 150
>>NP_612469 (OMIM: 607888) CKLF-like MARVEL transmembran (156 aa)
initn: 225 init1: 202 opt: 255 Z-score: 350.3 bits: 70.9 E(85289): 9e-13
Smith-Waterman score: 255; 35.7% identity (73.2% similar) in 112 aa overlap (19-130:29-139)
10 20 30 40 50
pF1KE1 MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFSASTPGYS
: ..::::: .:. : :.:.:::.:: .:
NP_612 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 SLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSIVVLVERGNHS
. ...:.... :. .: . . .. :::: ::.: . : :..:..:..... : . .
NP_612 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSR-DGA
70 80 90 100 110
120 130 140 150
pF1KE1 KIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
:.: :.:.: . .:.:::.
NP_612 AIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
120 130 140 150
>>XP_016876442 (OMIM: 607888) PREDICTED: CKLF-like MARVE (156 aa)
initn: 225 init1: 202 opt: 255 Z-score: 350.3 bits: 70.9 E(85289): 9e-13
Smith-Waterman score: 255; 35.7% identity (73.2% similar) in 112 aa overlap (19-130:29-139)
10 20 30 40 50
pF1KE1 MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFSASTPGYS
: ..::::: .:. : :.:.:::.:: .:
XP_016 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 SLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSIVVLVERGNHS
. ...:.... :. .: . . .. :::: ::.: . : :..:..:..... : . .
XP_016 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSR-DGA
70 80 90 100 110
120 130 140 150
pF1KE1 KIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
:.: :.:.: . .:.:::.
XP_016 AIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
120 130 140 150
>>XP_016876443 (OMIM: 607888) PREDICTED: CKLF-like MARVE (156 aa)
initn: 225 init1: 202 opt: 255 Z-score: 350.3 bits: 70.9 E(85289): 9e-13
Smith-Waterman score: 255; 35.7% identity (73.2% similar) in 112 aa overlap (19-130:29-139)
10 20 30 40 50
pF1KE1 MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFSASTPGYS
: ..::::: .:. : :.:.:::.:: .:
XP_016 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 SLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSIVVLVERGNHS
. ...:.... :. .: . . .. :::: ::.: . : :..:..:..... : . .
XP_016 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSR-DGA
70 80 90 100 110
120 130 140 150
pF1KE1 KIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
:.: :.:.: . .:.:::.
XP_016 AIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
120 130 140 150
>>NP_853531 (OMIM: 607886) CKLF-like MARVEL transmembran (182 aa)
initn: 218 init1: 152 opt: 217 Z-score: 298.3 bits: 61.5 E(85289): 7.1e-10
Smith-Waterman score: 217; 31.8% identity (64.3% similar) in 129 aa overlap (8-133:23-151)
10 20 30 40
pF1KE1 MADSERLSAPGCWA--ACTNFSRTRKGILLFAEIILCLVILICFS
..:: : : . :: ::.:: : .. .::.
NP_853 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 ASTPG-YSSLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSIVV
::. . . . ..:..:: :. . .:. : . :: ::.: . ::..:. ::..
NP_853 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 LVERGNHSKIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
... .. .. .:::.:..:: .:. : :. :
NP_853 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
130 140 150 160 170 180
NP_853 SD
>>XP_006721194 (OMIM: 607886) PREDICTED: CKLF-like MARVE (182 aa)
initn: 218 init1: 152 opt: 217 Z-score: 298.3 bits: 61.5 E(85289): 7.1e-10
Smith-Waterman score: 217; 31.8% identity (64.3% similar) in 129 aa overlap (8-133:23-151)
10 20 30 40
pF1KE1 MADSERLSAPGCWA--ACTNFSRTRKGILLFAEIILCLVILICFS
..:: : : . :: ::.:: : .. .::.
XP_006 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 ASTPG-YSSLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSIVV
::. . . . ..:..:: :. . .:. : . :: ::.: . ::..:. ::..
XP_006 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 LVERGNHSKIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
... .. .. .:::.:..:: .:. : :. :
XP_006 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
130 140 150 160 170 180
XP_006 SD
>>NP_653202 (OMIM: 607886) CKLF-like MARVEL transmembran (182 aa)
initn: 218 init1: 152 opt: 217 Z-score: 298.3 bits: 61.5 E(85289): 7.1e-10
Smith-Waterman score: 217; 31.8% identity (64.3% similar) in 129 aa overlap (8-133:23-151)
10 20 30 40
pF1KE1 MADSERLSAPGCWA--ACTNFSRTRKGILLFAEIILCLVILICFS
..:: : : . :: ::.:: : .. .::.
NP_653 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 ASTPG-YSSLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSIVV
::. . . . ..:..:: :. . .:. : . :: ::.: . ::..:. ::..
NP_653 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 LVERGNHSKIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
... .. .. .:::.:..:: .:. : :. :
NP_653 IAKYSDGASKAAGVFGFFATIVFATDFYLIFNDVAKFLKQGDSADETTAHKTEEENSDSD
130 140 150 160 170 180
NP_653 SD
>>NP_612419 (OMIM: 607890) CKLF-like MARVEL transmembran (175 aa)
initn: 201 init1: 97 opt: 192 Z-score: 265.0 bits: 55.3 E(85289): 5.1e-08
Smith-Waterman score: 192; 28.6% identity (65.1% similar) in 126 aa overlap (18-135:39-164)
10 20 30 40
pF1KE1 MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFSAST-
.. ::. ..: :... :. .:: .:
NP_612 RTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAFICVRSSLW
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 PGYSSLSVIE------MILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITSI
.::. : .: .:. :..:.. .. . :.:: :.... ::...: ::.::
NP_612 TNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGTLLLLIASI
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 VVLVERGNHSKIVAG-VLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
:. . :.: .::: ..:..:: : . .... .
NP_612 VAASKSYNQSGLVAGAIFGFMATFLCMASIWLSYKISCVTQSTDAAV
130 140 150 160 170
>>NP_852662 (OMIM: 607887) CKLF-like MARVEL transmembran (208 aa)
initn: 162 init1: 100 opt: 175 Z-score: 241.1 bits: 51.1 E(85289): 1.1e-06
Smith-Waterman score: 175; 28.2% identity (66.9% similar) in 124 aa overlap (18-131:48-170)
10 20 30 40
pF1KE1 MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFS---A
.. : : : :..:: :. .::. :
NP_852 SMISGASSPYQPTTEPVSQRRGLAGLRCDPDYLRGALGRLKVAQVILALIAFICIETIMA
20 30 40 50 60 70
50 60 70 80 90
pF1KE1 STP--G---YSSLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITS
.: : . .: ........... .:: .:: ::: .:. : ..:.:..:.:
NP_852 CSPCEGLYFFEFVSCSAFVVTGVLLIMFSLNLHMRIPQINWNLTDLVNTGLSAFLFFIAS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 IVV--LVERGNHSKIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
::. : .:.. ..:.: ..:..:: .. ....
NP_852 IVLAALNHRAG-AEIAAVIFGFLATAAYAVNTFLAVQKWRVSVRQQSTNDYIRARTESRD
140 150 160 170 180 190
NP_852 VDSRPEIQRLDT
200
>>XP_016878443 (OMIM: 607887) PREDICTED: CKLF-like MARVE (221 aa)
initn: 162 init1: 100 opt: 175 Z-score: 240.7 bits: 51.2 E(85289): 1.1e-06
Smith-Waterman score: 175; 28.2% identity (66.9% similar) in 124 aa overlap (18-131:48-170)
10 20 30 40
pF1KE1 MADSERLSAPGCWAACTNFSRTRKGILLFAEIILCLVILICFS---A
.. : : : :..:: :. .::. :
XP_016 SMISGASSPYQPTTEPVSQRRGLAGLRCDPDYLRGALGRLKVAQVILALIAFICIETIMA
20 30 40 50 60 70
50 60 70 80 90
pF1KE1 STP--G---YSSLSVIEMILAAIFFVVYMCDLHTKIPFINWPWSDFFRTLIAAILYLITS
.: : . .: ........... .:: .:: ::: .:. : ..:.:..:.:
XP_016 CSPCEGLYFFEFVSCSAFVVTGVLLIMFSLNLHMRIPQINWNLTDLVNTGLSAFLFFIAS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 IVV--LVERGNHSKIVAGVLGLIATCLFGYDAYVTFPVRQPRHTAAPTDPADGPV
::. : .:.. ..:.: ..:..:: .. ....
XP_016 IVLAALNHRAG-AEIAAVIFGFLATAAYAVNTFLAVQKWRVSVRQQSTNDYIRARTESRD
140 150 160 170 180 190
XP_016 VDSRPEIQRLDTLNWKPNGHQQVKG
200 210 220
152 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:42:58 2016 done: Sun Nov 6 09:42:58 2016
Total Scan time: 5.020 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]