Result of FASTA (omim) for
pFN21AE1623
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1623, 137 aa
1>>>pF1KE1623 137 - 137 aa - 137 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8452+/-0.000315; mu= 13.4516+/- 0.020
mean_var=57.6212+/-11.175, 0's: 0 Z-trim(115.5): 57 B-trim: 70 in 1/50
Lambda= 0.168960
statistics sampled from 25878 (25938) to 25878 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.304), width: 16
Scan time: 4.550
The best scores are: opt bits E(85289)
NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 908 229.0 1.9e-60
NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 506 131.0 5.3e-31
NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 306 82.2 2.4e-16
NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 244 67.0 7.1e-12
NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 242 66.5 1e-11
NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 242 66.5 1e-11
NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 238 65.6 2e-11
NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 233 64.4 5.3e-11
NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 215 60.0 9.6e-10
NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 209 58.5 2.6e-09
NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 204 57.3 6.1e-09
NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 191 54.1 5.5e-08
NP_002978 (OMIM: 601520) C-C motif chemokine 17 pr ( 94) 190 53.9 6.7e-08
XP_011521558 (OMIM: 601520) PREDICTED: C-C motif c ( 122) 190 53.9 8.2e-08
XP_016879019 (OMIM: 601520) PREDICTED: C-C motif c ( 123) 190 53.9 8.3e-08
NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 175 50.2 7.9e-07
XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 175 50.2 8.4e-07
NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 175 50.2 8.4e-07
XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 177 50.8 8.7e-07
NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 168 48.5 2.9e-06
XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 163 47.4 7.7e-06
NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 163 47.4 7.7e-06
XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 163 47.4 7.7e-06
NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 161 46.8 9.2e-06
NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 161 46.8 9.3e-06
NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 160 46.6 1.1e-05
NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 155 45.4 2.6e-05
NP_001278404 (OMIM: 610757) C-C motif chemokine 4- ( 103) 151 44.4 5.2e-05
XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 146 43.2 0.00014
NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 146 43.2 0.00014
NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 143 42.5 0.00025
XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 143 42.5 0.00027
NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 141 41.9 0.00027
NP_002986 (OMIM: 600250) lymphotactin precursor [H ( 114) 141 42.0 0.00031
XP_011508167 (OMIM: 600250) PREDICTED: lymphotacti ( 114) 141 42.0 0.00031
NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 139 41.4 0.00036
XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 139 41.4 0.00036
NP_003166 (OMIM: 604828) cytokine SCM-1 beta precu ( 114) 139 41.5 0.00043
NP_001123518 (OMIM: 601960) C-C motif chemokine 20 ( 95) 135 40.5 0.00073
NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 135 40.5 0.00074
NP_004582 (OMIM: 601960) C-C motif chemokine 20 is ( 96) 133 40.0 0.001
NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 133 40.0 0.0011
NP_001278399 (OMIM: 610757) C-C motif chemokine 4- ( 64) 129 38.9 0.0015
NP_001278398 (OMIM: 610757) C-C motif chemokine 4- ( 64) 129 38.9 0.0015
NP_001278402 (OMIM: 610757) C-C motif chemokine 4- ( 86) 129 39.0 0.0019
NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 129 39.0 0.002
NP_002987 (OMIM: 601880) fractalkine isoform 1 pre ( 397) 131 39.9 0.0046
>>NP_005055 (OMIM: 602494) C-C motif chemokine 23 isofor (137 aa)
initn: 908 init1: 908 opt: 908 Z-score: 1206.3 bits: 229.0 E(85289): 1.9e-60
Smith-Waterman score: 908; 99.3% identity (100.0% similar) in 137 aa overlap (1-137:1-137)
10 20 30 40 50 60
pF1KE1 MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AAGFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AAGFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQ
70 80 90 100 110 120
130
pF1KE1 VCVRMLKLDTRIKTRKN
::.::::::::::::::
NP_005 VCMRMLKLDTRIKTRKN
130
>>NP_665905 (OMIM: 602494) C-C motif chemokine 23 isofor (120 aa)
initn: 767 init1: 506 opt: 506 Z-score: 677.6 bits: 131.0 E(85289): 5.3e-31
Smith-Waterman score: 735; 86.1% identity (86.9% similar) in 137 aa overlap (1-137:1-120)
10 20 30 40 50 60
pF1KE1 MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSH
:::::::::::::::::::::::::::::::::::::::::::::
NP_665 MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDR--------------
10 20 30 40
70 80 90 100 110 120
pF1KE1 AAGFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 ---FHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQ
50 60 70 80 90 100
130
pF1KE1 VCVRMLKLDTRIKTRKN
::.::::::::::::::
NP_665 VCMRMLKLDTRIKTRKN
110 120
>>NP_116741 (OMIM: 601393) C-C motif chemokine 15 prepro (113 aa)
initn: 518 init1: 302 opt: 306 Z-score: 414.5 bits: 82.2 E(85289): 2.4e-16
Smith-Waterman score: 492; 63.8% identity (77.2% similar) in 127 aa overlap (1-127:1-109)
10 20 30 40 50 60
pF1KE1 MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSH
::::::::::::::..:::::. :.:::::.:::::::::::.:.
NP_116 MKVSVAALSCLMLVAVLGSQAQFTNDAETELMMSKLPLENPVVLN---------------
10 20 30 40
70 80 90 100 110 120
pF1KE1 AAGFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQ
.:: .:::: :: .::::::..:::::.::::::::::::::::. ::.:: ::
NP_116 --SFH-FAADCCTSYISQSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQ
50 60 70 80 90 100
130
pF1KE1 VCVRMLKLDTRIKTRKN
:.. ::
NP_116 DCMKKLKPYSI
110
>>NP_002974 (OMIM: 182283,609423) C-C motif chemokine 3 (92 aa)
initn: 268 init1: 237 opt: 244 Z-score: 334.1 bits: 67.0 E(85289): 7.1e-12
Smith-Waterman score: 244; 52.7% identity (77.0% similar) in 74 aa overlap (55-128:20-90)
30 40 50 60 70 80
pF1KE1 KDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIPCSL
:.. : :: : . ::.::: :.:: ..
NP_002 MQVSTAALAVLLCTMALCNQFSASLAAD---TPTACCFSYTSRQIPQNF
10 20 30 40
90 100 110 120 130
pF1KE1 LESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCVRMLKLDTRIKTRKN
. .::::.:.:::::::::::..:. ::.::.. :: : :.:
NP_002 IADYFETSSQCSKPGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA
50 60 70 80 90
>>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa)
initn: 268 init1: 237 opt: 242 Z-score: 331.4 bits: 66.5 E(85289): 1e-11
Smith-Waterman score: 242; 56.5% identity (82.3% similar) in 62 aa overlap (67-128:30-91)
40 50 60 70 80 90
pF1KE1 PLENPVLLDMLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIPCSLLESYFETNSECS
: . ::.::: :.:: ... .::::.:.::
NP_001 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCS
10 20 30 40 50
100 110 120 130
pF1KE1 KPGVIFLTKKGRRFCANPSDKQVQVCVRMLKLDTRIKTRKN
::.::::::.::. ::.::.. :: : :.:
NP_001 KPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA
60 70 80 90
>>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa)
initn: 268 init1: 237 opt: 242 Z-score: 331.4 bits: 66.5 E(85289): 1e-11
Smith-Waterman score: 242; 56.5% identity (82.3% similar) in 62 aa overlap (67-128:30-91)
40 50 60 70 80 90
pF1KE1 PLENPVLLDMLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIPCSLLESYFETNSECS
: . ::.::: :.:: ... .::::.:.::
NP_066 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCS
10 20 30 40 50
100 110 120 130
pF1KE1 KPGVIFLTKKGRRFCANPSDKQVQVCVRMLKLDTRIKTRKN
::.::::::.::. ::.::.. :: : :.:
NP_066 KPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA
60 70 80 90
>>NP_116739 (OMIM: 601392) C-C motif chemokine 14 isofor (93 aa)
initn: 267 init1: 227 opt: 238 Z-score: 326.2 bits: 65.6 E(85289): 2e-11
Smith-Waterman score: 238; 42.1% identity (72.4% similar) in 76 aa overlap (52-127:18-91)
30 40 50 60 70 80
pF1KE1 RVTKDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIP
.: . : . .: . .::..:: .::
NP_116 MKISVAAIPFFLLITIALGTKTESSSRGPYHPS--ECCFTYTTYKIP
10 20 30 40
90 100 110 120 130
pF1KE1 CSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCVRMLKLDTRIKTRKN
. . .:.::::.:::::..:.::.:. :.::::: :: .. .:
NP_116 RQRIMDYYETNSQCSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN
50 60 70 80 90
>>NP_116738 (OMIM: 601392) C-C motif chemokine 14 isofor (109 aa)
initn: 267 init1: 227 opt: 233 Z-score: 318.6 bits: 64.4 E(85289): 5.3e-11
Smith-Waterman score: 253; 35.9% identity (65.6% similar) in 128 aa overlap (1-127:1-107)
10 20 30 40 50
pF1KE1 MKVSVAALSCLMLVT-ALGSQARVTKDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLS
::.::::. ..:.: :::.... .... . . :. :. :. ::
NP_116 MKISVAAIPFFLLITIALGTKTESSSQTGGKPKVVKIQLK---LVG-------GP-----
10 20 30 40
60 70 80 90 100 110
pF1KE1 HAAGFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQV
.: . .::..:: .:: . . .:.::::.:::::..:.::.:. :.::::: :
NP_116 ----YHPS--ECCFTYTTYKIPRQRIMDYYETNSQCSKPGIVFITKRGHSVCTNPSDKWV
50 60 70 80 90
120 130
pF1KE1 QVCVRMLKLDTRIKTRKN
: .. .:
NP_116 QDYIKDMKEN
100
>>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa)
initn: 241 init1: 202 opt: 215 Z-score: 295.9 bits: 60.0 E(85289): 9.6e-10
Smith-Waterman score: 215; 43.2% identity (74.3% similar) in 74 aa overlap (56-129:20-92)
30 40 50 60 70 80
pF1KE1 DAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIPCSLL
..:: : .: ::.::: :..: ...
NP_996 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTA-CCFSYTARKLPRNFV
10 20 30 40
90 100 110 120 130
pF1KE1 ESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCVRMLKLDTRIKTRKN
.:.::.: ::.:.:.: ::.:.. ::.::.. :: : :.:.
NP_996 VDYYETSSLCSQPAVVFQTKRGKQVCADPSESWVQEYVYDLELN
50 60 70 80 90
>>NP_002979 (OMIM: 603757) C-C motif chemokine 18 precur (89 aa)
initn: 235 init1: 205 opt: 209 Z-score: 288.2 bits: 58.5 E(85289): 2.6e-09
Smith-Waterman score: 209; 43.2% identity (70.3% similar) in 74 aa overlap (56-129:15-88)
30 40 50 60 70 80
pF1KE1 DAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIPCSLL
:.: : ... ::. :: .:: ...
NP_002 MKGLAAALLVLVCTMALCSCAQVGTNKELCCLVYTSWQIPQKFI
10 20 30 40
90 100 110 120 130
pF1KE1 ESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCVRMLKLDTRIKTRKN
.: ::. .: :::::.:::.::..::.:. : :: . :::.
NP_002 VDYSETSPQCPKPGVILLTKRGRQICADPNKKWVQKYISDLKLNA
50 60 70 80
137 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:52:59 2016 done: Sun Nov 6 13:53:00 2016
Total Scan time: 4.550 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]