Result of FASTA (omim) for
pFN21AE1567
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1567, 418 aa
1>>>pF1KE1567 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5309+/-0.000383; mu= 21.1155+/- 0.024
mean_var=57.2778+/-11.426, 0's: 0 Z-trim(111.5): 70 B-trim: 330 in 1/55
Lambda= 0.169465
statistics sampled from 20076 (20146) to 20076 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.236), width: 16
Scan time: 8.310
The best scores are: opt bits E(85289)
NP_005992 (OMIM: 602528) tubulin alpha-3C/D chain ( 450) 2649 656.2 4.8e-188
NP_001257328 (OMIM: 602529,611603) tubulin alpha-1 ( 451) 2626 650.5 2.4e-186
NP_006000 (OMIM: 602529,611603) tubulin alpha-1A c ( 451) 2626 650.5 2.4e-186
NP_006073 (OMIM: 602530) tubulin alpha-1B chain [H ( 451) 2615 647.8 1.5e-185
NP_005991 (OMIM: 191110,616208) tubulin alpha-4A c ( 448) 2568 636.3 4.4e-182
NP_001265481 (OMIM: 191110,616208) tubulin alpha-4 ( 433) 2466 611.4 1.4e-174
NP_061816 (OMIM: 605742,613180) tubulin alpha-8 ch ( 449) 2441 605.3 9.8e-173
NP_001257329 (OMIM: 602529,611603) tubulin alpha-1 ( 416) 2364 586.4 4.3e-167
NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 ( 383) 2081 517.2 2.7e-146
XP_016860313 (OMIM: 191110,616208) PREDICTED: tubu ( 295) 1577 393.9 2.8e-109
NP_821133 (OMIM: 156610,191130,615771) tubulin bet ( 444) 1112 280.4 6.3e-75
NP_115914 (OMIM: 615103) tubulin beta-6 chain isof ( 446) 1104 278.4 2.5e-74
NP_001290453 (OMIM: 615103) tubulin beta-6 chain i ( 446) 1104 278.4 2.5e-74
NP_006079 (OMIM: 602660) tubulin beta-4B chain [Ho ( 445) 1100 277.4 4.8e-74
NP_006078 (OMIM: 602662) tubulin beta-4A chain iso ( 444) 1099 277.2 5.7e-74
NP_001276058 (OMIM: 602662) tubulin beta-4A chain ( 444) 1099 277.2 5.7e-74
NP_001276056 (OMIM: 602662) tubulin beta-4A chain ( 489) 1099 277.2 6.1e-74
NP_001276052 (OMIM: 602662) tubulin beta-4A chain ( 495) 1099 277.2 6.2e-74
NP_001060 (OMIM: 615101,615763) tubulin beta-2A ch ( 445) 1095 276.2 1.1e-73
NP_821080 (OMIM: 610031,612850) tubulin beta-2B ch ( 445) 1093 275.7 1.6e-73
NP_006077 (OMIM: 600638,602661,614039) tubulin bet ( 450) 1088 274.5 3.7e-73
NP_817124 (OMIM: 616768,616780) tubulin beta-8 cha ( 444) 1066 269.1 1.5e-71
NP_001280141 (OMIM: 156610,191130,615771) tubulin ( 464) 1050 265.2 2.4e-70
NP_110400 (OMIM: 612901,613112) tubulin beta-1 cha ( 451) 1042 263.3 9e-70
NP_001280143 (OMIM: 156610,191130,615771) tubulin ( 400) 981 248.3 2.5e-65
XP_016883574 (OMIM: 612901,613112) PREDICTED: tubu ( 429) 959 243.0 1.1e-63
NP_001290456 (OMIM: 615103) tubulin beta-6 chain i ( 374) 903 229.2 1.3e-59
NP_001280144 (OMIM: 156610,191130,615771) tubulin ( 372) 901 228.7 1.9e-59
NP_001280145 (OMIM: 156610,191130,615771) tubulin ( 372) 901 228.7 1.9e-59
NP_001276060 (OMIM: 602662) tubulin beta-4A chain ( 372) 896 227.5 4.3e-59
NP_001276059 (OMIM: 602662) tubulin beta-4A chain ( 372) 896 227.5 4.3e-59
NP_001184110 (OMIM: 600638,602661,614039) tubulin ( 378) 889 225.8 1.4e-58
XP_011517761 (OMIM: 616768,616780) PREDICTED: tubu ( 372) 880 223.6 6.5e-58
NP_001290457 (OMIM: 615103) tubulin beta-6 chain i ( 381) 842 214.3 4.2e-55
NP_001297244 (OMIM: 615101,615763) tubulin beta-2A ( 360) 829 211.1 3.6e-54
NP_001290455 (OMIM: 615103) tubulin beta-6 chain i ( 409) 829 211.2 4e-54
NP_001061 (OMIM: 191135,615412) tubulin gamma-1 ch ( 451) 767 196.0 1.6e-49
NP_057521 (OMIM: 605785) tubulin gamma-2 chain iso ( 451) 763 195.1 3.1e-49
XP_016871681 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 741 189.6 1e-47
XP_016871682 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 741 189.6 1e-47
NP_001290458 (OMIM: 615103) tubulin beta-6 chain i ( 300) 619 159.7 9e-39
NP_001290459 (OMIM: 615103) tubulin beta-6 chain i ( 300) 619 159.7 9e-39
XP_011517762 (OMIM: 616768,616780) PREDICTED: tubu ( 291) 566 146.7 7e-35
NP_001307438 (OMIM: 605785) tubulin gamma-2 chain ( 460) 494 129.3 2e-29
NP_057346 (OMIM: 607345) tubulin epsilon chain [Ho ( 475) 439 115.9 2.3e-25
NP_001280142 (OMIM: 156610,191130,615771) tubulin ( 242) 399 105.8 1.2e-22
XP_016866407 (OMIM: 607345) PREDICTED: tubulin eps ( 431) 392 104.3 6e-22
XP_016879942 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 388 103.2 8.9e-22
XP_011522916 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 388 103.2 8.9e-22
XP_016880205 (OMIM: 607344) PREDICTED: tubulin del ( 375) 372 99.4 1.6e-20
>>NP_005992 (OMIM: 602528) tubulin alpha-3C/D chain [Hom (450 aa)
initn: 2649 init1: 2649 opt: 2649 Z-score: 3496.9 bits: 656.2 E(85289): 4.8e-188
Smith-Waterman score: 2733; 92.9% identity (92.9% similar) in 450 aa overlap (1-418:1-450)
10 20 30 40 50 60
pF1KE1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
310 320 330 340 350 360
370 380 390
pF1KE1 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD----------------------------
::::::::::::::::::::::::::::::::
NP_005 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
370 380 390 400 410 420
400 410
pF1KE1 ----LAALEKDYEEVGVDSVEAEAEEGEEY
::::::::::::::::::::::::::
NP_005 AREDLAALEKDYEEVGVDSVEAEAEEGEEY
430 440 450
>>NP_001257328 (OMIM: 602529,611603) tubulin alpha-1A ch (451 aa)
initn: 2652 init1: 2626 opt: 2626 Z-score: 3466.5 bits: 650.5 E(85289): 2.4e-186
Smith-Waterman score: 2686; 90.5% identity (92.5% similar) in 451 aa overlap (1-418:1-451)
10 20 30 40 50 60
pF1KE1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
::::::::::::::.:::::::::::::::::::::::::::::::::::::::.:::::
NP_001 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
::::::: ::::::::.::::::::::::.:::::::::::::::::::.::::::::::
NP_001 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_001 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
310 320 330 340 350 360
370 380 390
pF1KE1 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD----------------------------
::::::::::::::::::::::::::::::::
NP_001 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
370 380 390 400 410 420
400 410
pF1KE1 ----LAALEKDYEEVGVDSVEAEAEE-GEEY
.::::::::::::::::.:.:: ::::
NP_001 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY
430 440 450
>>NP_006000 (OMIM: 602529,611603) tubulin alpha-1A chain (451 aa)
initn: 2652 init1: 2626 opt: 2626 Z-score: 3466.5 bits: 650.5 E(85289): 2.4e-186
Smith-Waterman score: 2686; 90.5% identity (92.5% similar) in 451 aa overlap (1-418:1-451)
10 20 30 40 50 60
pF1KE1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
::::::::::::::.:::::::::::::::::::::::::::::::::::::::.:::::
NP_006 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
::::::: ::::::::.::::::::::::.:::::::::::::::::::.::::::::::
NP_006 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_006 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
310 320 330 340 350 360
370 380 390
pF1KE1 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD----------------------------
::::::::::::::::::::::::::::::::
NP_006 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
370 380 390 400 410 420
400 410
pF1KE1 ----LAALEKDYEEVGVDSVEAEAEE-GEEY
.::::::::::::::::.:.:: ::::
NP_006 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY
430 440 450
>>NP_006073 (OMIM: 602530) tubulin alpha-1B chain [Homo (451 aa)
initn: 2641 init1: 2615 opt: 2615 Z-score: 3452.0 bits: 647.8 E(85289): 1.5e-185
Smith-Waterman score: 2675; 90.0% identity (92.5% similar) in 451 aa overlap (1-418:1-451)
10 20 30 40 50 60
pF1KE1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
::::::::::::::.:::::::::::::::::::::::::::::::::::::::.:::::
NP_006 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
::::::: ::::::::.::::::::::::.:::::::::::::::::::.::::::::::
NP_006 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_006 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
::::::::::::::::.::::::::::::::::::::::.::::::::::::::::::::
NP_006 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP
310 320 330 340 350 360
370 380 390
pF1KE1 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD----------------------------
::::::::::::::::::::::::::::::::
NP_006 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
370 380 390 400 410 420
400 410
pF1KE1 ----LAALEKDYEEVGVDSVEAEAEE-GEEY
.::::::::::::::::.:.:: ::::
NP_006 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY
430 440 450
>>NP_005991 (OMIM: 191110,616208) tubulin alpha-4A chain (448 aa)
initn: 2672 init1: 2568 opt: 2568 Z-score: 3389.9 bits: 636.3 E(85289): 4.4e-182
Smith-Waterman score: 2607; 87.3% identity (91.3% similar) in 449 aa overlap (1-417:1-448)
10 20 30 40 50 60
pF1KE1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
::::::.::::::::.:::::::::::::::::::::::::::::::::.::: ::::::
NP_005 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
::::::::::::::.::.:.: ::::::::::::::::::::::::::::::::.: :::
NP_005 HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
:::::.: ::::::::.::::::::::::.:::::::::::::::::::.::::::::::
NP_005 RIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_005 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
::::::::::::::::.::::::::::::::::.:::::.::::::::::::::::::::
NP_005 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP
310 320 330 340 350 360
370 380 390
pF1KE1 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD----------------------------
::::::::::::::::::::::::::::::::
NP_005 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
370 380 390 400 410 420
400 410
pF1KE1 ----LAALEKDYEEVGVDSVEAEAEEGEEY
.:::::::::::.:: : : .::::
NP_005 AREDMAALEKDYEEVGIDSYEDE-DEGEE
430 440
>>NP_001265481 (OMIM: 191110,616208) tubulin alpha-4A ch (433 aa)
initn: 2570 init1: 2466 opt: 2466 Z-score: 3255.4 bits: 611.4 E(85289): 1.4e-174
Smith-Waterman score: 2505; 87.1% identity (91.0% similar) in 434 aa overlap (16-417:1-433)
10 20 30 40 50 60
pF1KE1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
.:::::::::::::::::::::::::::::::::.::: ::::::
NP_001 MGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK
10 20 30 40
70 80 90 100 110 120
pF1KE1 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
::::::::::::::.::.:.: ::::::::::::::::::::::::::::::::.: :::
NP_001 HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
:::::.: ::::::::.::::::::::::.:::::::::::::::::::.::::::::::
NP_001 RIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_001 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
::::::::::::::::.::::::::::::::::.:::::.::::::::::::::::::::
NP_001 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP
290 300 310 320 330 340
370 380 390
pF1KE1 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD----------------------------
::::::::::::::::::::::::::::::::
NP_001 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
350 360 370 380 390 400
400 410
pF1KE1 ----LAALEKDYEEVGVDSVEAEAEEGEEY
.:::::::::::.:: : : .::::
NP_001 AREDMAALEKDYEEVGIDSYEDE-DEGEE
410 420 430
>>NP_061816 (OMIM: 605742,613180) tubulin alpha-8 chain (449 aa)
initn: 2545 init1: 2441 opt: 2441 Z-score: 3222.1 bits: 605.3 E(85289): 9.8e-173
Smith-Waterman score: 2481; 83.6% identity (89.8% similar) in 450 aa overlap (1-418:1-449)
10 20 30 40 50 60
pF1KE1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: ::
NP_061 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
::::::..:::::::::::.:::::::::::::::::::::::::::::.::: .:::::
NP_061 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
:::::.: :.:::::::::::::::::::.::::::::.:::::::::::::::::::::
NP_061 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_061 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
:::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: .
NP_061 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
:::::::::::::::::::::::::::::.:::.::::::::::::::::::::::::::
NP_061 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP
310 320 330 340 350 360
370 380 390
pF1KE1 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD----------------------------
::::::::::::::::::::::::::::::::
NP_061 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
370 380 390 400 410 420
400 410
pF1KE1 ----LAALEKDYEEVGVDSVEAEAEEGEEY
::::::::::::.:: : : .::::.
NP_061 AREDLAALEKDYEEVGTDSFEEE-NEGEEF
430 440
>>NP_001257329 (OMIM: 602529,611603) tubulin alpha-1A ch (416 aa)
initn: 2390 init1: 2364 opt: 2364 Z-score: 3120.8 bits: 586.4 E(85289): 4.3e-167
Smith-Waterman score: 2424; 89.7% identity (91.8% similar) in 416 aa overlap (36-418:1-416)
10 20 30 40 50 60
pF1KE1 SIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRA
::::::::::::::::::::::::::::::
NP_001 MPSDKTIGGGDDSFNTFFSETGAGKHVPRA
10 20 30
70 80 90 100 110 120
pF1KE1 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKL
:::::::::.:::::::::::::::::::::::::::::::::::::::.::::::::::
NP_001 VFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 ADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPY
:: ::::::::.::::::::::::.:::::::::::::::::::.:::::::::::::::
NP_001 ADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPY
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 NSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFD
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 GALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKC
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 DPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPG
280 290 300 310 320 330
370 380 390
pF1KE1 GDLAKVQRAVCMLSNTTAIAEAWARLD--------------------------------L
::::::::::::::::::::::::::: .
NP_001 GDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDM
340 350 360 370 380 390
400 410
pF1KE1 AALEKDYEEVGVDSVEAEAEE-GEEY
::::::::::::::::.:.:: ::::
NP_001 AALEKDYEEVGVDSVEGEGEEEGEEY
400 410
>>NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 cha (383 aa)
initn: 2185 init1: 2081 opt: 2081 Z-score: 2747.4 bits: 517.2 E(85289): 2.7e-146
Smith-Waterman score: 2121; 85.1% identity (90.1% similar) in 383 aa overlap (68-418:2-383)
40 50 60 70 80 90
pF1KE1 SDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKE
.:::::::::::.:::::::::::::::::
NP_001 MIDLEPTVVDEVRAGTYRQLFHPEQLITGKE
10 20 30
100 110 120 130 140 150
pF1KE1 DAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERL
::::::::::::.::: .::::::::::.: :.:::::::::::::::::::.:::::::
NP_001 DAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE1 SVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNL
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE1 DIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVIS
::::::::::::::.:::::::::::::::::::::::::::::::::::::.::::.::
NP_001 DIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIIS
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE1 AEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKT
:::::::::::::::..:::: .:::::::::::::::::::::::::::::.:::.:::
NP_001 AEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKT
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE1 KRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDL
280 290 300 310 320 330
400 410
pF1KE1 ---------------------------LAALEKDYEEVGVDSVEAEAEEGEEY
::::::::::::.:: : : .::::.
NP_001 MYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFE-EENEGEEF
340 350 360 370 380
>>XP_016860313 (OMIM: 191110,616208) PREDICTED: tubulin (295 aa)
initn: 1681 init1: 1577 opt: 1577 Z-score: 2083.0 bits: 393.9 E(85289): 2.8e-109
Smith-Waterman score: 1616; 85.5% identity (88.2% similar) in 296 aa overlap (154-417:1-295)
130 140 150 160 170 180
pF1KE1 KLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVE
::::::::::::::::.:::::::::::::
XP_016 MERLSVDYGKKSKLEFSIYPAPQVSTAVVE
10 20 30
190 200 210 220 230 240
pF1KE1 PYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLR
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_016 PYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLR
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE1 FDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMV
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE1 KCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVV
:::::::::::::.::::::::::::::::.:::::.:::::::::::::::::::::::
XP_016 KCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVV
160 170 180 190 200 210
370 380 390
pF1KE1 PGGDLAKVQRAVCMLSNTTAIAEAWARLD-------------------------------
:::::::::::::::::::::::::::::
XP_016 PGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARE
220 230 240 250 260 270
400 410
pF1KE1 -LAALEKDYEEVGVDSVEAEAEEGEEY
.:::::::::::.:: : : .::::
XP_016 DMAALEKDYEEVGIDSYEDE-DEGEE
280 290
418 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:49:27 2016 done: Mon Nov 7 01:49:29 2016
Total Scan time: 8.310 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]