Result of FASTA (omim) for
pFN21AE1559
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1559, 495 aa
1>>>pF1KE1559 495 - 495 aa - 495 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3784+/-0.000299; mu= 10.2466+/- 0.019
mean_var=136.9024+/-27.386, 0's: 0 Z-trim(121.1): 71 B-trim: 53 in 1/59
Lambda= 0.109615
statistics sampled from 37067 (37143) to 37067 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.435), width: 16
Scan time: 11.340
The best scores are: opt bits E(85289)
NP_055022 (OMIM: 153340) T-cell surface glycoprote ( 495) 3456 557.6 2.9e-158
NP_001333385 (OMIM: 153340) T-cell surface glycopr ( 438) 3054 494.0 3.6e-139
XP_011537700 (OMIM: 601969) PREDICTED: deleted in (2521) 366 69.4 1.4e-10
XP_011537717 (OMIM: 601969) PREDICTED: deleted in (1766) 344 65.8 1.1e-09
XP_011537715 (OMIM: 601969) PREDICTED: deleted in (2282) 344 65.9 1.4e-09
XP_011537713 (OMIM: 601969) PREDICTED: deleted in (2403) 344 65.9 1.5e-09
XP_011537711 (OMIM: 601969) PREDICTED: deleted in (2411) 344 65.9 1.5e-09
XP_011537712 (OMIM: 601969) PREDICTED: deleted in (2411) 344 65.9 1.5e-09
XP_011537709 (OMIM: 601969) PREDICTED: deleted in (2411) 344 65.9 1.5e-09
NP_001307573 (OMIM: 601969) deleted in malignant b (2412) 344 65.9 1.5e-09
XP_011537705 (OMIM: 601969) PREDICTED: deleted in (2413) 344 65.9 1.5e-09
NP_015568 (OMIM: 601969) deleted in malignant brai (2413) 344 65.9 1.5e-09
XP_011537703 (OMIM: 601969) PREDICTED: deleted in (2413) 344 65.9 1.5e-09
XP_011537707 (OMIM: 601969) PREDICTED: deleted in (2413) 344 65.9 1.5e-09
XP_006717728 (OMIM: 601969) PREDICTED: deleted in (2510) 344 65.9 1.5e-09
XP_011537701 (OMIM: 601969) PREDICTED: deleted in (2510) 344 65.9 1.5e-09
XP_011537698 (OMIM: 601969) PREDICTED: deleted in (2526) 344 65.9 1.5e-09
XP_006717723 (OMIM: 601969) PREDICTED: deleted in (2526) 344 65.9 1.5e-09
XP_011537695 (OMIM: 601969) PREDICTED: deleted in (2532) 344 65.9 1.5e-09
XP_011537696 (OMIM: 601969) PREDICTED: deleted in (2532) 344 65.9 1.5e-09
XP_011537694 (OMIM: 601969) PREDICTED: deleted in (2532) 344 65.9 1.5e-09
XP_011537692 (OMIM: 601969) PREDICTED: deleted in (2532) 344 65.9 1.5e-09
XP_011537697 (OMIM: 601969) PREDICTED: deleted in (2532) 344 65.9 1.5e-09
XP_011537691 (OMIM: 601969) PREDICTED: deleted in (2541) 344 65.9 1.5e-09
XP_011537690 (OMIM: 601969) PREDICTED: deleted in (2542) 344 65.9 1.5e-09
XP_011537710 (OMIM: 601969) PREDICTED: deleted in (2411) 342 65.6 1.8e-09
XP_011537704 (OMIM: 601969) PREDICTED: deleted in (2413) 332 64.0 5.5e-09
XP_011537716 (OMIM: 601969) PREDICTED: deleted in (1783) 263 53.0 8.2e-06
NP_004397 (OMIM: 601969) deleted in malignant brai (1785) 263 53.0 8.3e-06
XP_011537702 (OMIM: 601969) PREDICTED: deleted in (2434) 263 53.1 1.1e-05
XP_016871287 (OMIM: 601969) PREDICTED: deleted in (1990) 245 50.2 6.5e-05
NP_060049 (OMIM: 601969) deleted in malignant brai (2403) 246 50.4 6.8e-05
XP_011537693 (OMIM: 601969) PREDICTED: deleted in (2532) 246 50.4 7.1e-05
NP_115992 (OMIM: 607163) lysyl oxidase homolog 3 i ( 753) 213 44.9 0.00099
XP_011531436 (OMIM: 607163) PREDICTED: lysyl oxida ( 753) 213 44.9 0.00099
>>NP_055022 (OMIM: 153340) T-cell surface glycoprotein C (495 aa)
initn: 3456 init1: 3456 opt: 3456 Z-score: 2962.3 bits: 557.6 E(85289): 2.9e-158
Smith-Waterman score: 3456; 99.6% identity (100.0% similar) in 495 aa overlap (1-495:1-495)
10 20 30 40 50 60
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 NSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 KKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 TGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSRLSAYPALEGVLHRSSMQPD
::::::::::::::::::::::::::::::::::::::::.:::::::::.:::::::::
NP_055 TGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPD
430 440 450 460 470 480
490
pF1KE1 NSSDSDYDLHGAQRL
:::::::::::::::
NP_055 NSSDSDYDLHGAQRL
490
>>NP_001333385 (OMIM: 153340) T-cell surface glycoprotei (438 aa)
initn: 3054 init1: 3054 opt: 3054 Z-score: 2619.5 bits: 494.0 E(85289): 3.6e-139
Smith-Waterman score: 3054; 99.5% identity (100.0% similar) in 438 aa overlap (58-495:1-438)
30 40 50 60 70 80
pF1KE1 WYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCG
::::::::::::::::::::::::::::::
NP_001 MVCSQSWGRSSKQWEDPSQASKVCQRLNCG
10 20 30
90 100 110 120 130 140
pF1KE1 VPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTTPPTTRPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTTPPTTRPPP
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 TTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCG
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 SFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLC
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 SGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSY
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 RVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILAL
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE1 VLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGPTGMNQNMSFHRNHTATVRSHAENPTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGPTGMNQNMSFHRNHTATVRSHAENPTAS
340 350 360 370 380 390
450 460 470 480 490
pF1KE1 HVDNEYSQPPRNSRLSAYPALEGVLHRSSMQPDNSSDSDYDLHGAQRL
:::::::::::::.:::::::::.::::::::::::::::::::::::
NP_001 HVDNEYSQPPRNSHLSAYPALEGALHRSSMQPDNSSDSDYDLHGAQRL
400 410 420 430
>>XP_011537700 (OMIM: 601969) PREDICTED: deleted in mali (2521 aa)
initn: 310 init1: 114 opt: 366 Z-score: 311.1 bits: 69.4 E(85289): 1.4e-10
Smith-Waterman score: 366; 28.2% identity (55.4% similar) in 316 aa overlap (30-326:97-390)
10 20 30 40 50
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMV
: . ::. ....:::..:. . .: :
XP_011 SLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTV
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE1 CSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGS
:..:: : ..:. ::..:.:: .: .: . . :. : : :. .
XP_011 CDDSW--------DTNDANVVCRQLGCGWAMS-APGNAWFGQGSGPIALDDVRCSGHESY
130 140 150 160 170
120 130 140 150 160
pF1KE1 FSNCSHSR--NDMC-HS--LGLTC--LEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQ
. .: :. . : :. :. : .::.: : . : . : :: . : :
XP_011 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE1 SGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQD
.::..: : :: .: :: : :. . : :.: : .: .: :: .. ... :...
XP_011 NGGDRCRGRVEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSG
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE1 P---GEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVG
: . : :. ... . ..: .. . .: ..::: . .. :::.
XP_011 PIVLDDVRCSGHESYLWSCPHNGWLT-HNCGHS---EDAG----VICSGPESSLALRLVN
300 310 320 330 340
290 300 310 320 330 340
pF1KE1 GSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGL
:.. :.: ::: ..:...::.: :. . :::. :: ..:
XP_011 GGDRCQGRVEVLYRGSWGTVCDDSWDTSDA--NVVCRQLGCGWATSAPGNARFGQGSGPI
350 360 370 380 390 400
350 360 370 380 390 400
pF1KE1 FCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPL
XP_011 VLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPAST
410 420 430 440 450 460
>--
initn: 177 init1: 108 opt: 250 Z-score: 212.0 bits: 51.1 E(85289): 4.5e-05
Smith-Waterman score: 307; 27.4% identity (51.3% similar) in 318 aa overlap (36-322:842-1145)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
820 830 840 850 860 870
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
XP_011 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
880 890 900 910 920
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
XP_011 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
930 940 950 960 970 980
180 190 200 210 220
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEP
: :: .:.:: : :. .. : :.: : .: .: :: .. ... :... : .
XP_011 GRVEVLYQGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV
990 1000 1010 1020 1030
230 240 250 260 270
pF1KE1 REHQPLPIQWKIQNS-----SCTSLEH----CF-RKIKPQKSGRVLALL---CSGFQPKV
: :. .. .: : : . .: : . .: . ..
XP_011 RCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSL
1040 1050 1060 1070 1080 1090
280 290 300 310 320 330
pF1KE1 QSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGD
:::.:.. :.: ::: ..:...::. .. . :::. ::
XP_011 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQLGCGWAMSAPGNARFG
1100 1110 1120 1130 1140 1150
340 350 360 370 380 390
pF1KE1 PTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLL
XP_011 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTS
1160 1170 1180 1190 1200 1210
>--
initn: 442 init1: 98 opt: 231 Z-score: 195.8 bits: 48.1 E(85289): 0.00036
Smith-Waterman score: 287; 26.2% identity (50.3% similar) in 320 aa overlap (36-326:1231-1536)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::.. :
XP_011 SASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYW-
1210 1220 1230 1240 1250
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: ..:. ::..:.:: : .: . . :. : : :. . . .: :
XP_011 -------DTNDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGHESYLWSCPH
1260 1270 1280 1290 1300 1310
120 130 140 150 160 170
pF1KE1 ----SRNDMCH-SLGLTCLEPQKTTPPTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGV
:.: : . :. : :. :. ::. . . : : .::..: :
XP_011 NGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGR
1320 1330 1340 1350 1360 1370
180 190 200 210 220
pF1KE1 VE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPRE
:: .: :: : :. . : :.: : .: .: :: . ... :... : . :
XP_011 VEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
1380 1390 1400 1410 1420
230 240 250 260 270
pF1KE1 HQPLPIQWKIQNS-----SCTSLEH----CF-RKIKPQKSGRVLALL---CSGFQPKVQS
:. .. .: : : . .: : . .: . ..
XP_011 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL
1430 1440 1450 1460 1470 1480
280 290 300 310 320 330
pF1KE1 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPT
:::.:.. :.: ::: ..:...::. .. . :::. :: ..:
XP_011 RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQLGCGWATSAPGNARFGQG
1490 1500 1510 1520 1530 1540
340 350 360 370 380 390
pF1KE1 SRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVV
XP_011 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA
1550 1560 1570 1580 1590 1600
>--
initn: 205 init1: 114 opt: 231 Z-score: 195.8 bits: 48.1 E(85289): 0.00036
Smith-Waterman score: 277; 27.1% identity (50.7% similar) in 339 aa overlap (18-326:460-760)
10 20 30 40
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQ
: :: .: : .. ::. ....:::.
XP_011 NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES----SLALRLVNGGDRCQGR
430 440 450 460 470 480
50 60 70 80 90 100
pF1KE1 LEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII-
.:: . .: ::..:: : ..:. ::..:.:: . :.: . . :. :
XP_011 VEVLYRGSWGTVCDDSW--------DTNDANVVCRQLGCGWAM-LAPGNARFGQGSGPIV
490 500 510 520 530
110 120 130 140 150
pF1KE1 -----CYGQLGSFSNCSHSR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTTPEPTAP
: :. . . .: :. . : :: :. : :...
XP_011 LDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLA----------------
540 550 560 570 580
160 170 180 190 200 210
pF1KE1 PRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPE
:.:: .::..: : :: .: :: : :. .. : :.: : .: .: :: . .
XP_011 --LRLV--NGGDRCQGRVEVLYRGSWG-TVCDDSWD-TND-ANVVCRQLGCGWATSAPGN
590 600 610 620 630
220 230 240 250
pF1KE1 TEAGRAQDP---GEPREHQPLPIQWKIQNS-----SCTSLEH----CF----RKI-KPQK
.. :... : . : :. :. .: : : :. .:.
XP_011 ARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDT
640 650 660 670 680 690
260 270 280 290 300 310
pF1KE1 SGRV-LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCR
. . : : . .. :::.::. :.: ::: ..:...::.: .. . :::
XP_011 LSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDA--NVVCR
700 710 720 730 740 750
320 330 340 350 360 370
pF1KE1 EQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAA
. :: ..:
XP_011 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC
760 770 780 790 800 810
>>XP_011537717 (OMIM: 601969) PREDICTED: deleted in mali (1766 aa)
initn: 295 init1: 114 opt: 344 Z-score: 294.6 bits: 65.8 E(85289): 1.1e-09
Smith-Waterman score: 344; 28.8% identity (54.7% similar) in 309 aa overlap (36-326:364-650)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
340 350 360 370 380 390
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
XP_011 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
400 410 420 430 440
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
XP_011 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
450 460 470 480 490 500
180 190 200 210 220
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEP
: :: .: :: : :. .. : :.: : .: .: :: . ... :... : .
XP_011 GRVEVLYRGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDV
510 520 530 540 550 560
230 240 250 260 270 280
pF1KE1 REHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEG
: :. ... : ..: .. . .: ..::: . .. :::.:.. :.:
XP_011 RCSGNESYLWSCPHNGWLS-HNCGHS---EDAG----VICSGPESSLALRLVNGGDRCQG
570 580 590 600 610
290 300 310 320 330 340
pF1KE1 TVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKL
::: ..:...::.: .. . :::. :: ..:
XP_011 RVEVLYRGSWGTVCDDSWDTNDA--NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
620 630 640 650 660 670
350 360 370 380 390 400
pF1KE1 SQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVK
XP_011 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL
680 690 700 710 720 730
>--
initn: 303 init1: 110 opt: 267 Z-score: 228.8 bits: 53.6 E(85289): 5.3e-06
Smith-Waterman score: 267; 29.4% identity (55.0% similar) in 211 aa overlap (30-224:97-295)
10 20 30 40 50
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMV
: . ::. ....:::..:. . .: :
XP_011 SLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTV
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE1 CSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGS
:..:: : ..:. ::..:.:: .: .: . . :. : : :. .
XP_011 CDDSW--------DTNDANVVCRQLGCGWAMS-APGNAWFGQGSGPIALDDVRCSGHESY
130 140 150 160 170
120 130 140 150 160
pF1KE1 FSNCSHSR--NDMC-HS--LGLTC--LEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQ
. .: :. . : :. :. : .::.: : . : . : :: . : :
XP_011 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE1 SGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQD
.::..: : :: .: :: : :. . : :.: : .: .: :: .. ... :...
XP_011 NGGDRCRGRVEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSG
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE1 PGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSS
:
XP_011 PIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHAST
300 310 320 330 340 350
>--
initn: 215 init1: 108 opt: 250 Z-score: 214.2 bits: 51.0 E(85289): 3.4e-05
Smith-Waterman score: 250; 30.4% identity (54.9% similar) in 204 aa overlap (36-224:863-1054)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
840 850 860 870 880 890
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
XP_011 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
900 910 920 930 940
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
XP_011 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
950 960 970 980 990 1000
180 190 200 210 220 230
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREH
: :: .:.:: : :. .. : :.: : .: .: :: .. ... :... :
XP_011 GRVEVLYQGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV
1010 1020 1030 1040 1050 1060
240 250 260 270 280 290
pF1KE1 QPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVE
XP_011 RCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCG
1070 1080 1090 1100 1110 1120
>>XP_011537715 (OMIM: 601969) PREDICTED: deleted in mali (2282 aa)
initn: 210 init1: 114 opt: 344 Z-score: 293.0 bits: 65.9 E(85289): 1.4e-09
Smith-Waterman score: 344; 28.8% identity (54.7% similar) in 309 aa overlap (36-326:364-650)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
340 350 360 370 380 390
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
XP_011 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
400 410 420 430 440
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
XP_011 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
450 460 470 480 490 500
180 190 200 210 220
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEP
: :: .: :: : :. .. : :.: : .: .: :: . ... :... : .
XP_011 GRVEVLYRGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDV
510 520 530 540 550 560
230 240 250 260 270 280
pF1KE1 REHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEG
: :. ... : ..: .. . .: ..::: . .. :::.:.. :.:
XP_011 RCSGNESYLWSCPHNGWLS-HNCGHS---EDAG----VICSGPESSLALRLVNGGDRCQG
570 580 590 600 610
290 300 310 320 330 340
pF1KE1 TVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKL
::: ..:...::.: .. . :::. :: ..:
XP_011 RVEVLYRGSWGTVCDDSWDTNDA--NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
620 630 640 650 660 670
350 360 370 380 390 400
pF1KE1 SQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVK
XP_011 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLPTITLPASTVGSESSL
680 690 700 710 720 730
>--
initn: 303 init1: 110 opt: 267 Z-score: 227.2 bits: 53.7 E(85289): 6.5e-06
Smith-Waterman score: 267; 29.4% identity (55.0% similar) in 211 aa overlap (30-224:97-295)
10 20 30 40 50
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMV
: . ::. ....:::..:. . .: :
XP_011 SLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTV
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE1 CSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGS
:..:: : ..:. ::..:.:: .: .: . . :. : : :. .
XP_011 CDDSW--------DTNDANVVCRQLGCGWAMS-APGNAWFGQGSGPIALDDVRCSGHESY
130 140 150 160 170
120 130 140 150 160
pF1KE1 FSNCSHSR--NDMC-HS--LGLTC--LEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQ
. .: :. . : :. :. : .::.: : . : . : :: . : :
XP_011 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE1 SGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQD
.::..: : :: .: :: : :. . : :.: : .: .: :: .. ... :...
XP_011 NGGDRCRGRVEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSG
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE1 PGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSS
:
XP_011 PIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHAST
300 310 320 330 340 350
>--
initn: 104 init1: 104 opt: 247 Z-score: 210.1 bits: 50.6 E(85289): 5.8e-05
Smith-Waterman score: 304; 26.6% identity (50.9% similar) in 338 aa overlap (18-326:720-1039)
10 20 30 40
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQ
: :: .: : .. ::. ....:::.
XP_011 NCGHHEDAGVICSAAQSRSTPRPDTLPTITLPASTVGSES----SLALRLVNGGDRCQGR
690 700 710 720 730 740
50 60 70 80 90 100
pF1KE1 LEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII-
.:: . .: ::..:: : ..:. ::..:.:: .: .: . . :. :
XP_011 VEVLYQGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMS-APGNARFGQGSGPIV
750 760 770 780 790
110 120 130 140 150
pF1KE1 -----CYGQLGSFSNCSHSR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTTPEPT-A
: :. . . .: :. . : :: :. : :. :. ::. . .
XP_011 LDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGS
800 810 820 830 840 850
160 170 180 190 200 210
pF1KE1 PPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLP
: : .::..: : :: .: :: : :. . : :.: : .: .: :: ..
XP_011 ESSLALRLVNGGDRCQGRVEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPG
860 870 880 890 900 910
220 230 240 250 260
pF1KE1 ETEAGRAQDP---GEPREHQPLPIQWKIQNS-----SCTSLEH----CF-RKIKPQKSGR
... :... : . : :. .. .: : : . .: :
XP_011 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPD
920 930 940 950 960 970
270 280 290 300 310
pF1KE1 VLALL---CSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCRE
. .: . .. :::.:.. :.: ::: ..:...::. .. . :::.
XP_011 TWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQ
980 990 1000 1010 1020 1030
320 330 340 350 360 370
pF1KE1 QQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAG
:: ..:
XP_011 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS
1040 1050 1060 1070 1080 1090
>>XP_011537713 (OMIM: 601969) PREDICTED: deleted in mali (2403 aa)
initn: 210 init1: 114 opt: 344 Z-score: 292.6 bits: 65.9 E(85289): 1.5e-09
Smith-Waterman score: 344; 28.8% identity (54.7% similar) in 309 aa overlap (36-326:364-650)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
340 350 360 370 380 390
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
XP_011 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
400 410 420 430 440
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
XP_011 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
450 460 470 480 490 500
180 190 200 210 220
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEP
: :: .: :: : :. .. : :.: : .: .: :: . ... :... : .
XP_011 GRVEVLYRGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDV
510 520 530 540 550 560
230 240 250 260 270 280
pF1KE1 REHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEG
: :. ... : ..: .. . .: ..::: . .. :::.:.. :.:
XP_011 RCSGNESYLWSCPHNGWLS-HNCGHS---EDAG----VICSGPESSLALRLVNGGDRCQG
570 580 590 600 610
290 300 310 320 330 340
pF1KE1 TVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKL
::: ..:...::.: .. . :::. :: ..:
XP_011 RVEVLYRGSWGTVCDDSWDTNDA--NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
620 630 640 650 660 670
350 360 370 380 390 400
pF1KE1 SQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVK
XP_011 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL
680 690 700 710 720 730
>--
initn: 106 init1: 106 opt: 300 Z-score: 255.0 bits: 59.0 E(85289): 1.8e-07
Smith-Waterman score: 304; 26.6% identity (50.9% similar) in 338 aa overlap (18-326:841-1160)
10 20 30 40
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQ
: :: .: : .. ::. ....:::.
XP_011 SCPHNGWLSHNCGHHEDAGVICSDTLPTITLPASTVGSES----SLALRLVNGGDRCQGR
820 830 840 850 860
50 60 70 80 90 100
pF1KE1 LEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII-
.:: . .: ::..:: : ..:. ::..:.:: .: .: . . :. :
XP_011 VEVLYQGSWGTVCDDSW--------DTNDANVVCRQLGCGWAMS-APGNARFGQGSGPIV
870 880 890 900 910
110 120 130 140 150
pF1KE1 -----CYGQLGSFSNCSHSR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTTPEPT-A
: :. . . .: :. . : :: :. : :. :. ::. . .
XP_011 LDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGS
920 930 940 950 960 970
160 170 180 190 200 210
pF1KE1 PPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLP
: : .::..: : :: .: :: : :. . : :.: : .: .: :: ..
XP_011 ESSLALRLVNGGDRCQGRVEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPG
980 990 1000 1010 1020 1030
220 230 240 250 260
pF1KE1 ETEAGRAQDP---GEPREHQPLPIQWKIQNS-----SCTSLEH----CF-RKIKPQKSGR
... :... : . : :. .. .: : : . .: :
XP_011 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPD
1040 1050 1060 1070 1080 1090
270 280 290 300 310
pF1KE1 VLALL---CSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCRE
. .: . .. :::.:.. :.: ::: ..:...::. .. . :::.
XP_011 TWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQ
1100 1110 1120 1130 1140 1150
320 330 340 350 360 370
pF1KE1 QQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAG
:: ..:
XP_011 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS
1160 1170 1180 1190 1200 1210
>--
initn: 303 init1: 110 opt: 267 Z-score: 226.8 bits: 53.7 E(85289): 6.8e-06
Smith-Waterman score: 267; 29.4% identity (55.0% similar) in 211 aa overlap (30-224:97-295)
10 20 30 40 50
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMV
: . ::. ....:::..:. . .: :
XP_011 SLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTV
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE1 CSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGS
:..:: : ..:. ::..:.:: .: .: . . :. : : :. .
XP_011 CDDSW--------DTNDANVVCRQLGCGWAMS-APGNAWFGQGSGPIALDDVRCSGHESY
130 140 150 160 170
120 130 140 150 160
pF1KE1 FSNCSHSR--NDMC-HS--LGLTC--LEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQ
. .: :. . : :. :. : .::.: : . : . : :: . : :
XP_011 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE1 SGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQD
.::..: : :: .: :: : :. . : :.: : .: .: :: .. ... :...
XP_011 NGGDRCRGRVEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSG
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE1 PGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSS
:
XP_011 PIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHAST
300 310 320 330 340 350
>>XP_011537711 (OMIM: 601969) PREDICTED: deleted in mali (2411 aa)
initn: 210 init1: 114 opt: 344 Z-score: 292.6 bits: 65.9 E(85289): 1.5e-09
Smith-Waterman score: 344; 28.8% identity (54.7% similar) in 309 aa overlap (36-326:364-650)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
340 350 360 370 380 390
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
XP_011 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
400 410 420 430 440
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
XP_011 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
450 460 470 480 490 500
180 190 200 210 220
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEP
: :: .: :: : :. .. : :.: : .: .: :: . ... :... : .
XP_011 GRVEVLYRGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDV
510 520 530 540 550 560
230 240 250 260 270 280
pF1KE1 REHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEG
: :. ... : ..: .. . .: ..::: . .. :::.:.. :.:
XP_011 RCSGNESYLWSCPHNGWLS-HNCGHS---EDAG----VICSGPESSLALRLVNGGDRCQG
570 580 590 600 610
290 300 310 320 330 340
pF1KE1 TVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKL
::: ..:...::.: .. . :::. :: ..:
XP_011 RVEVLYRGSWGTVCDDSWDTNDA--NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
620 630 640 650 660 670
350 360 370 380 390 400
pF1KE1 SQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVK
XP_011 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL
680 690 700 710 720 730
>--
initn: 303 init1: 110 opt: 267 Z-score: 226.8 bits: 53.7 E(85289): 6.8e-06
Smith-Waterman score: 267; 29.4% identity (55.0% similar) in 211 aa overlap (30-224:97-295)
10 20 30 40 50
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMV
: . ::. ....:::..:. . .: :
XP_011 SLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTV
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE1 CSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGS
:..:: : ..:. ::..:.:: .: .: . . :. : : :. .
XP_011 CDDSW--------DTNDANVVCRQLGCGWAMS-APGNAWFGQGSGPIALDDVRCSGHESY
130 140 150 160 170
120 130 140 150 160
pF1KE1 FSNCSHSR--NDMC-HS--LGLTC--LEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQ
. .: :. . : :. :. : .::.: : . : . : :: . : :
XP_011 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE1 SGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQD
.::..: : :: .: :: : :. . : :.: : .: .: :: .. ... :...
XP_011 NGGDRCRGRVEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSG
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE1 PGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSS
:
XP_011 PIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHAST
300 310 320 330 340 350
>--
initn: 177 init1: 108 opt: 245 Z-score: 208.0 bits: 50.3 E(85289): 7.6e-05
Smith-Waterman score: 302; 26.9% identity (50.6% similar) in 320 aa overlap (36-326:863-1168)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
840 850 860 870 880 890
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
XP_011 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
900 910 920 930 940
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGV
. . : :: :. : :. :. ::. . . : : .::..: :
XP_011 NGWLSHNCQHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGR
950 960 970 980 990 1000
180 190 200 210 220
pF1KE1 VE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPRE
:: .: :: : :. . : :.: : .: .: :: .. ... :... : . :
XP_011 VEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC
1010 1020 1030 1040 1050 1060
230 240 250 260 270
pF1KE1 HQPLPIQWKIQNS-----SCTSLEH----CF-RKIKPQKSGRVLALL---CSGFQPKVQS
:. .. .: : : . .: : . .: . ..
XP_011 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL
1070 1080 1090 1100 1110 1120
280 290 300 310 320 330
pF1KE1 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPT
:::.:.. :.: ::: ..:...::. .. . :::. :: ..:
XP_011 RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQLGCGWATSAPGNARFGQG
1130 1140 1150 1160 1170
340 350 360 370 380 390
pF1KE1 SRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVV
XP_011 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA
1180 1190 1200 1210 1220 1230
>>XP_011537712 (OMIM: 601969) PREDICTED: deleted in mali (2411 aa)
initn: 210 init1: 114 opt: 344 Z-score: 292.6 bits: 65.9 E(85289): 1.5e-09
Smith-Waterman score: 344; 28.8% identity (54.7% similar) in 309 aa overlap (36-326:364-650)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
340 350 360 370 380 390
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
XP_011 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
400 410 420 430 440
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
XP_011 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
450 460 470 480 490 500
180 190 200 210 220
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEP
: :: .: :: : :. .. : :.: : .: .: :: . ... :... : .
XP_011 GRVEVLYRGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDV
510 520 530 540 550 560
230 240 250 260 270 280
pF1KE1 REHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEG
: :. ... : ..: .. . .: ..::: . .. :::.:.. :.:
XP_011 RCSGNESYLWSCPHNGWLS-HNCGHS---EDAG----VICSGPESSLALRLVNGGDRCQG
570 580 590 600 610
290 300 310 320 330 340
pF1KE1 TVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKL
::: ..:...::.: .. . :::. :: ..:
XP_011 RVEVLYRGSWGTVCDDSWDTNDA--NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
620 630 640 650 660 670
350 360 370 380 390 400
pF1KE1 SQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVK
XP_011 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL
680 690 700 710 720 730
>--
initn: 303 init1: 110 opt: 267 Z-score: 226.8 bits: 53.7 E(85289): 6.8e-06
Smith-Waterman score: 267; 29.4% identity (55.0% similar) in 211 aa overlap (30-224:97-295)
10 20 30 40 50
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMV
: . ::. ....:::..:. . .: :
XP_011 SLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTV
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE1 CSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGS
:..:: : ..:. ::..:.:: .: .: . . :. : : :. .
XP_011 CDDSW--------DTNDANVVCRQLGCGWAMS-APGNAWFGQGSGPIALDDVRCSGHESY
130 140 150 160 170
120 130 140 150 160
pF1KE1 FSNCSHSR--NDMC-HS--LGLTC--LEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQ
. .: :. . : :. :. : .::.: : . : . : :: . : :
XP_011 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE1 SGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQD
.::..: : :: .: :: : :. . : :.: : .: .: :: .. ... :...
XP_011 NGGDRCRGRVEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSG
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE1 PGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSS
:
XP_011 PIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHAST
300 310 320 330 340 350
>--
initn: 240 init1: 108 opt: 250 Z-score: 212.3 bits: 51.0 E(85289): 4.4e-05
Smith-Waterman score: 307; 27.4% identity (51.3% similar) in 318 aa overlap (36-322:863-1166)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
840 850 860 870 880 890
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
XP_011 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
900 910 920 930 940
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
XP_011 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
950 960 970 980 990 1000
180 190 200 210 220
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEP
: :: .:.:: : :. .. : :.: : .: .: :: .. ... :... : .
XP_011 GRVEVLYQGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV
1010 1020 1030 1040 1050 1060
230 240 250 260 270
pF1KE1 REHQPLPIQWKIQNS-----SCTSLEH----CF-RKIKPQKSGRVLALL---CSGFQPKV
: :. .. .: : : . .: : . .: . ..
XP_011 RCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSL
1070 1080 1090 1100 1110 1120
280 290 300 310 320 330
pF1KE1 QSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGD
:::.:.. :.: ::: ..:...::. .. . :::. ::
XP_011 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQLGCGWAMSAPGNARFG
1130 1140 1150 1160 1170
340 350 360 370 380 390
pF1KE1 PTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLL
XP_011 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTS
1180 1190 1200 1210 1220 1230
>--
initn: 401 init1: 98 opt: 231 Z-score: 196.0 bits: 48.0 E(85289): 0.00035
Smith-Waterman score: 287; 26.2% identity (50.3% similar) in 320 aa overlap (36-326:1252-1557)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::.. :
XP_011 SASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYW-
1230 1240 1250 1260 1270 1280
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: ..:. ::..:.:: : .: . . :. : : :. . . .: :
XP_011 -------DTNDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGHESYLWSCPH
1290 1300 1310 1320 1330
120 130 140 150 160 170
pF1KE1 ----SRNDMCH-SLGLTCLEPQKTTPPTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGV
:.: : . :. : :. :. ::. . . : : .::..: :
XP_011 NGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGR
1340 1350 1360 1370 1380 1390
180 190 200 210 220
pF1KE1 VE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPRE
:: .: :: : :. . : :.: : .: .: :: . ... :... : . :
XP_011 VEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
1400 1410 1420 1430 1440
230 240 250 260 270
pF1KE1 HQPLPIQWKIQNS-----SCTSLEH----CF-RKIKPQKSGRVLALL---CSGFQPKVQS
:. .. .: : : . .: : . .: . ..
XP_011 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL
1450 1460 1470 1480 1490 1500
280 290 300 310 320 330
pF1KE1 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPT
:::.:.. :.: ::: ..:...::. .. . :::. :: ..:
XP_011 RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQLGCGWATSAPGNARFGQG
1510 1520 1530 1540 1550 1560
340 350 360 370 380 390
pF1KE1 SRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVV
XP_011 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA
1570 1580 1590 1600 1610 1620
>>XP_011537709 (OMIM: 601969) PREDICTED: deleted in mali (2411 aa)
initn: 210 init1: 114 opt: 344 Z-score: 292.6 bits: 65.9 E(85289): 1.5e-09
Smith-Waterman score: 344; 28.8% identity (54.7% similar) in 309 aa overlap (36-326:364-650)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
340 350 360 370 380 390
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
XP_011 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
400 410 420 430 440
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
XP_011 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
450 460 470 480 490 500
180 190 200 210 220
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEP
: :: .: :: : :. .. : :.: : .: .: :: . ... :... : .
XP_011 GRVEVLYRGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDV
510 520 530 540 550 560
230 240 250 260 270 280
pF1KE1 REHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEG
: :. ... : ..: .. . .: ..::: . .. :::.:.. :.:
XP_011 RCSGNESYLWSCPHNGWLS-HNCGHS---EDAG----VICSGPESSLALRLVNGGDRCQG
570 580 590 600 610
290 300 310 320 330 340
pF1KE1 TVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKL
::: ..:...::.: .. . :::. :: ..:
XP_011 RVEVLYRGSWGTVCDDSWDTNDA--NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
620 630 640 650 660 670
350 360 370 380 390 400
pF1KE1 SQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVK
XP_011 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL
680 690 700 710 720 730
>--
initn: 303 init1: 110 opt: 267 Z-score: 226.8 bits: 53.7 E(85289): 6.8e-06
Smith-Waterman score: 267; 29.4% identity (55.0% similar) in 211 aa overlap (30-224:97-295)
10 20 30 40 50
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMV
: . ::. ....:::..:. . .: :
XP_011 SLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTV
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE1 CSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGS
:..:: : ..:. ::..:.:: .: .: . . :. : : :. .
XP_011 CDDSW--------DTNDANVVCRQLGCGWAMS-APGNAWFGQGSGPIALDDVRCSGHESY
130 140 150 160 170
120 130 140 150 160
pF1KE1 FSNCSHSR--NDMC-HS--LGLTC--LEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQ
. .: :. . : :. :. : .::.: : . : . : :: . : :
XP_011 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE1 SGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQD
.::..: : :: .: :: : :. . : :.: : .: .: :: .. ... :...
XP_011 NGGDRCRGRVEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSG
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE1 PGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSS
:
XP_011 PIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHAST
300 310 320 330 340 350
>--
initn: 175 init1: 106 opt: 244 Z-score: 207.2 bits: 50.1 E(85289): 8.4e-05
Smith-Waterman score: 303; 26.6% identity (51.2% similar) in 320 aa overlap (36-326:863-1168)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
XP_011 SVSQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSW-
840 850 860 870 880 890
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: ..:. ::..:.:: .: .: . . :. : : :. . . .: :
XP_011 -------DTNDANVVCRQLGCGWAMS-APGNARFGQGSGPIVLDDVRCSGHESYLWSCPH
900 910 920 930 940
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTTPEPT-APPRLQLVAQSGGQHCAGV
. . : :: :. : :. :. ::. . . : : .::..: :
XP_011 NGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGR
950 960 970 980 990 1000
180 190 200 210 220
pF1KE1 VE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEPRE
:: .: :: : :. . : :.: : .: .: :: .. ... :... : . :
XP_011 VEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC
1010 1020 1030 1040 1050 1060
230 240 250 260 270
pF1KE1 HQPLPIQWKIQNS-----SCTSLEH----CF-RKIKPQKSGRVLALL---CSGFQPKVQS
:. .. .: : : . .: : . .: . ..
XP_011 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL
1070 1080 1090 1100 1110 1120
280 290 300 310 320 330
pF1KE1 RLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPT
:::.:.. :.: ::: ..:...::. .. . :::. :: ..:
XP_011 RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQLGCGWATSAPGNARFGQG
1130 1140 1150 1160 1170
340 350 360 370 380 390
pF1KE1 SRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVV
XP_011 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA
1180 1190 1200 1210 1220 1230
>>NP_001307573 (OMIM: 601969) deleted in malignant brain (2412 aa)
initn: 210 init1: 114 opt: 344 Z-score: 292.6 bits: 65.9 E(85289): 1.5e-09
Smith-Waterman score: 344; 28.8% identity (54.7% similar) in 309 aa overlap (36-326:364-650)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
NP_001 SAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
340 350 360 370 380 390
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
NP_001 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
400 410 420 430 440
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
NP_001 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
450 460 470 480 490 500
180 190 200 210 220
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEP
: :: .: :: : :. .. : :.: : .: .: :: . ... :... : .
NP_001 GRVEVLYRGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDV
510 520 530 540 550 560
230 240 250 260 270 280
pF1KE1 REHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEG
: :. ... : ..: .. . .: ..::: . .. :::.:.. :.:
NP_001 RCSGNESYLWSCPHNGWLS-HNCGHS---EDAG----VICSGPESSLALRLVNGGDRCQG
570 580 590 600 610
290 300 310 320 330 340
pF1KE1 TVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKL
::: ..:...::.: .. . :::. :: ..:
NP_001 RVEVLYRGSWGTVCDDSWDTNDA--NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
620 630 640 650 660 670
350 360 370 380 390 400
pF1KE1 SQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVK
NP_001 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL
680 690 700 710 720 730
>--
initn: 303 init1: 110 opt: 267 Z-score: 226.8 bits: 53.7 E(85289): 6.8e-06
Smith-Waterman score: 267; 29.4% identity (55.0% similar) in 211 aa overlap (30-224:97-295)
10 20 30 40 50
pF1KE1 MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMV
: . ::. ....:::..:. . .: :
NP_001 SLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTV
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE1 CSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGS
:..:: : ..:. ::..:.:: .: .: . . :. : : :. .
NP_001 CDDSW--------DTNDANVVCRQLGCGWAMS-APGNAWFGQGSGPIALDDVRCSGHESY
130 140 150 160 170
120 130 140 150 160
pF1KE1 FSNCSHSR--NDMC-HS--LGLTC--LEPQKTTPPTTRPPPTTTPEPT--APPRLQLVAQ
. .: :. . : :. :. : .::.: : . : . : :: . : :
NP_001 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE1 SGGQHCAGVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQD
.::..: : :: .: :: : :. . : :.: : .: .: :: .. ... :...
NP_001 NGGDRCRGRVEVLYRGSWG-TVCDDYWD-TND-ANVVCRQLGCGWAMSAPGNAQFGQGSG
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE1 PGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSS
:
NP_001 PIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHAST
300 310 320 330 340 350
>--
initn: 240 init1: 108 opt: 250 Z-score: 212.3 bits: 51.0 E(85289): 4.4e-05
Smith-Waterman score: 307; 27.4% identity (51.3% similar) in 318 aa overlap (36-322:863-1166)
10 20 30 40 50 60
pF1KE1 LQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWG
::. ....:::..:: . .: ::..::
NP_001 SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW-
840 850 860 870 880 890
70 80 90 100 110
pF1KE1 RSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSII------CYGQLGSFSNCSH
: :.:. ::..:.:: : .: . . :. : : : . . .: :
NP_001 -------DTSDANVVCRQLGCGWATS-APGNARFGQGSGPIVLDDVRCSGYESYLWSCPH
900 910 920 930 940
120 130 140 150 160 170
pF1KE1 SR--NDMC-HS--LGLTCLEPQKTTPPTTRPPPTTT-PEPT--APPRLQLVAQSGGQHCA
. . : :: :. : .. . :. :: : : : . : : .::..:
NP_001 NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ
950 960 970 980 990 1000
180 190 200 210 220
pF1KE1 GVVE-FYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP---GEP
: :: .:.:: : :. .. : :.: : .: .: :: .. ... :... : .
NP_001 GRVEVLYQGSWG-TVCDDSWD-TND-ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV
1010 1020 1030 1040 1050 1060
230 240 250 260 270
pF1KE1 REHQPLPIQWKIQNS-----SCTSLEH----CF-RKIKPQKSGRVLALL---CSGFQPKV
: :. .. .: : : . .: : . .: . ..
NP_001 RCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSL
1070 1080 1090 1100 1110 1120
280 290 300 310 320 330
pF1KE1 QSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGD
:::.:.. :.: ::: ..:...::. .. . :::. ::
NP_001 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA--NVVCRQLGCGWAMSAPGNARFG
1130 1140 1150 1160 1170
340 350 360 370 380 390
pF1KE1 PTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLL
NP_001 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTS
1180 1190 1200 1210 1220 1230
495 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:25:16 2016 done: Mon Nov 7 00:25:18 2016
Total Scan time: 11.340 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]