Result of FASTA (omim) for
pFN21AE1553
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1553, 632 aa
1>>>pF1KE1553 632 - 632 aa - 632 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1651+/-0.000465; mu= 10.0751+/- 0.028
mean_var=172.2128+/-38.513, 0's: 0 Z-trim(114.8): 313 B-trim: 1086 in 2/55
Lambda= 0.097733
statistics sampled from 24378 (24836) to 24378 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.291), width: 16
Scan time: 11.270
The best scores are: opt bits E(85289)
NP_116011 (OMIM: 609732) E3 ubiquitin-protein liga ( 632) 4241 611.3 3.3e-174
NP_001119800 (OMIM: 609732) E3 ubiquitin-protein l ( 728) 4045 583.7 7.7e-166
XP_016864265 (OMIM: 609732) PREDICTED: E3 ubiquiti ( 728) 4045 583.7 7.7e-166
XP_005265842 (OMIM: 609732) PREDICTED: E3 ubiquiti ( 728) 4045 583.7 7.7e-166
XP_016875923 (OMIM: 609733) PREDICTED: ligand of N ( 690) 1651 246.1 3e-64
NP_699202 (OMIM: 609733) ligand of Numb protein X ( 690) 1651 246.1 3e-64
XP_011533297 (OMIM: 609733) PREDICTED: ligand of N ( 567) 932 144.6 8.7e-34
XP_016870743 (OMIM: 603785,615219) PREDICTED: mult (2000) 743 118.5 2.2e-25
XP_016870744 (OMIM: 603785,615219) PREDICTED: mult (2000) 743 118.5 2.2e-25
XP_005251680 (OMIM: 603785,615219) PREDICTED: mult (2000) 743 118.5 2.2e-25
XP_006716952 (OMIM: 603785,615219) PREDICTED: mult (2037) 743 118.6 2.3e-25
NP_001248335 (OMIM: 603785,615219) multiple PDZ do (2037) 743 118.6 2.3e-25
XP_006716950 (OMIM: 603785,615219) PREDICTED: mult (2070) 743 118.6 2.3e-25
NP_001317566 (OMIM: 603785,615219) multiple PDZ do (2070) 743 118.6 2.3e-25
XP_006716949 (OMIM: 603785,615219) PREDICTED: mult (2070) 743 118.6 2.3e-25
XP_006716948 (OMIM: 603785,615219) PREDICTED: mult (2070) 743 118.6 2.3e-25
XP_016870741 (OMIM: 603785,615219) PREDICTED: mult (2042) 595 97.7 4.3e-19
NP_795352 (OMIM: 603199) inaD-like protein [Homo s (1801) 383 67.7 3.9e-10
XP_016870746 (OMIM: 603785,615219) PREDICTED: mult (1971) 379 67.2 6.2e-10
XP_016870745 (OMIM: 603785,615219) PREDICTED: mult (1971) 379 67.2 6.2e-10
XP_006716954 (OMIM: 603785,615219) PREDICTED: mult (2008) 379 67.2 6.3e-10
NP_001248336 (OMIM: 603785,615219) multiple PDZ do (2008) 379 67.2 6.3e-10
XP_016870742 (OMIM: 603785,615219) PREDICTED: mult (2008) 379 67.2 6.3e-10
NP_003820 (OMIM: 603785,615219) multiple PDZ domai (2041) 379 67.2 6.4e-10
XP_006716951 (OMIM: 603785,615219) PREDICTED: mult (2041) 379 67.2 6.4e-10
XP_005270398 (OMIM: 603199) PREDICTED: inaD-like p (1882) 360 64.5 3.8e-09
XP_011538768 (OMIM: 603199) PREDICTED: inaD-like p (1907) 355 63.8 6.3e-09
XP_011538769 (OMIM: 603199) PREDICTED: inaD-like p (1856) 322 59.2 1.6e-07
NP_001305120 (OMIM: 613323) FERM and PDZ domain-co (1284) 303 56.3 7.7e-07
NP_001018081 (OMIM: 613323) FERM and PDZ domain-co (1309) 303 56.3 7.8e-07
XP_016855490 (OMIM: 603199) PREDICTED: inaD-like p ( 992) 299 55.6 9.5e-07
XP_016855489 (OMIM: 603199) PREDICTED: inaD-like p (1634) 299 55.9 1.4e-06
XP_011538767 (OMIM: 603199) PREDICTED: inaD-like p (1912) 299 55.9 1.5e-06
XP_011538766 (OMIM: 603199) PREDICTED: inaD-like p (1921) 299 55.9 1.5e-06
XP_011538765 (OMIM: 603199) PREDICTED: inaD-like p (1937) 299 55.9 1.5e-06
XP_011538764 (OMIM: 603199) PREDICTED: inaD-like p (1937) 299 55.9 1.5e-06
XP_005252593 (OMIM: 606745) PREDICTED: partitionin ( 741) 281 53.0 4.5e-06
XP_011517886 (OMIM: 606745) PREDICTED: partitionin ( 744) 281 53.0 4.5e-06
NP_001171722 (OMIM: 606745) partitioning defective (1000) 281 53.1 5.6e-06
XP_016871919 (OMIM: 606745) PREDICTED: partitionin (1015) 281 53.1 5.6e-06
XP_005252591 (OMIM: 606745) PREDICTED: partitionin (1030) 281 53.1 5.7e-06
NP_001171721 (OMIM: 606745) partitioning defective (1031) 281 53.1 5.7e-06
XP_011517885 (OMIM: 606745) PREDICTED: partitionin (1034) 281 53.1 5.7e-06
XP_011517883 (OMIM: 606745) PREDICTED: partitionin (1144) 281 53.2 6.1e-06
XP_011517881 (OMIM: 606745) PREDICTED: partitionin (1278) 281 53.2 6.6e-06
XP_005252589 (OMIM: 606745) PREDICTED: partitionin (1309) 281 53.2 6.7e-06
XP_011517878 (OMIM: 606745) PREDICTED: partitionin (1312) 281 53.2 6.7e-06
NP_001171716 (OMIM: 606745) partitioning defective (1319) 281 53.2 6.8e-06
XP_011517877 (OMIM: 606745) PREDICTED: partitionin (1322) 281 53.2 6.8e-06
XP_005252588 (OMIM: 606745) PREDICTED: partitionin (1323) 281 53.2 6.8e-06
>>NP_116011 (OMIM: 609732) E3 ubiquitin-protein ligase L (632 aa)
initn: 4241 init1: 4241 opt: 4241 Z-score: 3248.5 bits: 611.3 E(85289): 3.3e-174
Smith-Waterman score: 4241; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KE1 MKALLLLVLPWLSPANYIDNVGNLHFLYSELCKGASHYGLTKDRKRRSQDGCPDGCASLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MKALLLLVLPWLSPANYIDNVGNLHFLYSELCKGASHYGLTKDRKRRSQDGCPDGCASLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ATAPSPEVSAAATISLMTDEPGLDNPAYVSSAEDGQPAISPVDSGRSNRTRARPFERSTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ATAPSPEVSAAATISLMTDEPGLDNPAYVSSAEDGQPAISPVDSGRSNRTRARPFERSTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFPRLYHLIPDGEITSIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 RSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFPRLYHLIPDGEITSIK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 INRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 INRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 HNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 HNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 HLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVVNIQKDPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 HLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVVNIQKDPGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 LLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSNHNMAPPSDWSPSWVMWLELPRCLYNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSNHNMAPPSDWSPSWVMWLELPRCLYNC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 KDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 KDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRS
550 560 570 580 590 600
610 620 630
pF1KE1 TSGMIHACLARLLKELKGRITLTIVSWPGTFL
::::::::::::::::::::::::::::::::
NP_116 TSGMIHACLARLLKELKGRITLTIVSWPGTFL
610 620 630
>>NP_001119800 (OMIM: 609732) E3 ubiquitin-protein ligas (728 aa)
initn: 4039 init1: 4039 opt: 4045 Z-score: 3098.3 bits: 583.7 E(85289): 7.7e-166
Smith-Waterman score: 4045; 96.3% identity (97.9% similar) in 628 aa overlap (5-632:101-728)
10 20 30
pF1KE1 MKALLLLVLPWLSPANYIDNVGNLHFLYSELCKG
::.. :. . . . .:. .. :::
NP_001 EKDFCPMDRKPLVLQHCKKSSILVNKLLNKLLVTCPFREHCTQVLQRCDLEHHFQTSCKG
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE1 ASHYGLTKDRKRRSQDGCPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASHYGLTKDRKRRSQDGCPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAED
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE1 GQPAISPVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGREN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQPAISPVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGREN
200 210 220 230 240 250
160 170 180 190 200 210
pF1KE1 SENTTAPEVFPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SENTTAPEVFPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDG
260 270 280 290 300 310
220 230 240 250 260 270
pF1KE1 VIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAP
320 330 340 350 360 370
280 290 300 310 320 330
pF1KE1 DAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVL
380 390 400 410 420 430
340 350 360 370 380 390
pF1KE1 AINGHDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AINGHDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGER
440 450 460 470 480 490
400 410 420 430 440 450
pF1KE1 SNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDG
500 510 520 530 540 550
460 470 480 490 500 510
pF1KE1 RIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSN
560 570 580 590 600 610
520 530 540 550 560 570
pF1KE1 HNMAPPSDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNMAPPSDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKS
620 630 640 650 660 670
580 590 600 610 620 630
pF1KE1 IVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL
680 690 700 710 720
>>XP_016864265 (OMIM: 609732) PREDICTED: E3 ubiquitin-pr (728 aa)
initn: 4039 init1: 4039 opt: 4045 Z-score: 3098.3 bits: 583.7 E(85289): 7.7e-166
Smith-Waterman score: 4045; 96.3% identity (97.9% similar) in 628 aa overlap (5-632:101-728)
10 20 30
pF1KE1 MKALLLLVLPWLSPANYIDNVGNLHFLYSELCKG
::.. :. . . . .:. .. :::
XP_016 EKDFCPMDRKPLVLQHCKKSSILVNKLLNKLLVTCPFREHCTQVLQRCDLEHHFQTSCKG
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE1 ASHYGLTKDRKRRSQDGCPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASHYGLTKDRKRRSQDGCPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAED
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE1 GQPAISPVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGREN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQPAISPVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGREN
200 210 220 230 240 250
160 170 180 190 200 210
pF1KE1 SENTTAPEVFPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SENTTAPEVFPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDG
260 270 280 290 300 310
220 230 240 250 260 270
pF1KE1 VIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAP
320 330 340 350 360 370
280 290 300 310 320 330
pF1KE1 DAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVL
380 390 400 410 420 430
340 350 360 370 380 390
pF1KE1 AINGHDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AINGHDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGER
440 450 460 470 480 490
400 410 420 430 440 450
pF1KE1 SNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDG
500 510 520 530 540 550
460 470 480 490 500 510
pF1KE1 RIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSN
560 570 580 590 600 610
520 530 540 550 560 570
pF1KE1 HNMAPPSDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNMAPPSDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKS
620 630 640 650 660 670
580 590 600 610 620 630
pF1KE1 IVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL
680 690 700 710 720
>>XP_005265842 (OMIM: 609732) PREDICTED: E3 ubiquitin-pr (728 aa)
initn: 4039 init1: 4039 opt: 4045 Z-score: 3098.3 bits: 583.7 E(85289): 7.7e-166
Smith-Waterman score: 4045; 96.3% identity (97.9% similar) in 628 aa overlap (5-632:101-728)
10 20 30
pF1KE1 MKALLLLVLPWLSPANYIDNVGNLHFLYSELCKG
::.. :. . . . .:. .. :::
XP_005 EKDFCPMDRKPLVLQHCKKSSILVNKLLNKLLVTCPFREHCTQVLQRCDLEHHFQTSCKG
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE1 ASHYGLTKDRKRRSQDGCPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASHYGLTKDRKRRSQDGCPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAED
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE1 GQPAISPVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGREN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQPAISPVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGREN
200 210 220 230 240 250
160 170 180 190 200 210
pF1KE1 SENTTAPEVFPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SENTTAPEVFPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDG
260 270 280 290 300 310
220 230 240 250 260 270
pF1KE1 VIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAP
320 330 340 350 360 370
280 290 300 310 320 330
pF1KE1 DAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVL
380 390 400 410 420 430
340 350 360 370 380 390
pF1KE1 AINGHDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AINGHDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGER
440 450 460 470 480 490
400 410 420 430 440 450
pF1KE1 SNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDG
500 510 520 530 540 550
460 470 480 490 500 510
pF1KE1 RIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSN
560 570 580 590 600 610
520 530 540 550 560 570
pF1KE1 HNMAPPSDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HNMAPPSDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKS
620 630 640 650 660 670
580 590 600 610 620 630
pF1KE1 IVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL
680 690 700 710 720
>>XP_016875923 (OMIM: 609733) PREDICTED: ligand of Numb (690 aa)
initn: 1682 init1: 508 opt: 1651 Z-score: 1274.3 bits: 246.1 E(85289): 3e-64
Smith-Waterman score: 1651; 50.9% identity (77.7% similar) in 511 aa overlap (131-632:185-690)
110 120 130 140 150
pF1KE1 PVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENS--ENT
:. : :. :.: . . : .: :..
XP_016 TQAEIENENGPTLLDPAGTLSPEADCLGTGAVPVERHLTSASLSTWSEEPGLDNPAFEES
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE1 TAPEVFPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIAR
.. .. . : :.::::.:.:.: .: .:.: .:::.::::..:.::..::::::::
XP_016 AGADTTQQPLSL-PEGEITTIEIHRSNPYIQLGISIVGGNETPLINIVIQEVYRDGVIAR
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE1 DGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYR
::::: :: ::.::...:::: :::: .: :::..: :::.::..: .: .... :.
XP_016 DGRLLAGDQILQVNNYNISNVSHNYARAVLSQPCNTLHLTVLRERRFGNRAHNHS-DSNS
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE1 PRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAING
::.. :.: :.: . :::::::::..:::::::...:.::.: . :.: :::::::::
XP_016 PREEIFQVALHKRDSGEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLSSNDRVLAING
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE1 HDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSW--SPGPG-ERS
:::.::.:: ::..:::: .::.:...: . . . ..::: .:..: .: : :
XP_016 HDLKYGTPELAAQIIQASGERVNLTIARPGKPQPGNTIREAGNHSSSSQHHTPPPYYSRP
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE1 NTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGR
.. : : .::.:: ....:.: :::::::::: . . .:::.: :: : : ..::::
XP_016 SSHKDLTQCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGR
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE1 IKTGDILLNVDGVELTEVSRSEAVALLKRTSSS--IVLKALEVK--EYEPQEDCSSPAAL
:: ::.:::..:..::..:.:::::.:: ...: ..::::::. : :. .:...
XP_016 IKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVALKALEVQIVEEATQNAEEQPSTF
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE1 DSNHNMAPPSDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFF
. :. : .::::::::: :: :..:.::::::. :: :: ::::::: . :.:::
XP_016 SENEYDA---SWSPSWVMWLGLPSTLHSCHDIVLRRSYLGSWGFSIVGGYEENHTNQPFF
580 590 600 610 620
580 590 600 610 620 630
pF1KE1 IKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTF
::.:: ::::: :::..:::...:::: :: :: :. :. .::: ....:::.. :::..
XP_016 IKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVICWPGSL
630 640 650 660 670 680
pF1KE1 L
.
XP_016 V
690
>>NP_699202 (OMIM: 609733) ligand of Numb protein X 2 [H (690 aa)
initn: 1682 init1: 508 opt: 1651 Z-score: 1274.3 bits: 246.1 E(85289): 3e-64
Smith-Waterman score: 1651; 50.9% identity (77.7% similar) in 511 aa overlap (131-632:185-690)
110 120 130 140 150
pF1KE1 PVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENS--ENT
:. : :. :.: . . : .: :..
NP_699 TQAEIENENGPTLLDPAGTLSPEADCLGTGAVPVERHLTSASLSTWSEEPGLDNPAFEES
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE1 TAPEVFPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIAR
.. .. . : :.::::.:.:.: .: .:.: .:::.::::..:.::..::::::::
NP_699 AGADTTQQPLSL-PEGEITTIEIHRSNPYIQLGISIVGGNETPLINIVIQEVYRDGVIAR
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE1 DGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYR
::::: :: ::.::...:::: :::: .: :::..: :::.::..: .: .... :.
NP_699 DGRLLAGDQILQVNNYNISNVSHNYARAVLSQPCNTLHLTVLRERRFGNRAHNHS-DSNS
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE1 PRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAING
::.. :.: :.: . :::::::::..:::::::...:.::.: . :.: :::::::::
NP_699 PREEIFQVALHKRDSGEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLSSNDRVLAING
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE1 HDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSW--SPGPG-ERS
:::.::.:: ::..:::: .::.:...: . . . ..::: .:..: .: : :
NP_699 HDLKYGTPELAAQIIQASGERVNLTIARPGKPQPGNTIREAGNHSSSSQHHTPPPYYSRP
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE1 NTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGR
.. : : .::.:: ....:.: :::::::::: . . .:::.: :: : : ..::::
NP_699 SSHKDLTQCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGR
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE1 IKTGDILLNVDGVELTEVSRSEAVALLKRTSSS--IVLKALEVK--EYEPQEDCSSPAAL
:: ::.:::..:..::..:.:::::.:: ...: ..::::::. : :. .:...
NP_699 IKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVALKALEVQIVEEATQNAEEQPSTF
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE1 DSNHNMAPPSDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFF
. :. : .::::::::: :: :..:.::::::. :: :: ::::::: . :.:::
NP_699 SENEYDA---SWSPSWVMWLGLPSTLHSCHDIVLRRSYLGSWGFSIVGGYEENHTNQPFF
580 590 600 610 620
580 590 600 610 620 630
pF1KE1 IKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTF
::.:: ::::: :::..:::...:::: :: :: :. :. .::: ....:::.. :::..
NP_699 IKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVICWPGSL
630 640 650 660 670 680
pF1KE1 L
.
NP_699 V
690
>>XP_011533297 (OMIM: 609733) PREDICTED: ligand of Numb (567 aa)
initn: 1273 init1: 508 opt: 932 Z-score: 727.5 bits: 144.6 E(85289): 8.7e-34
Smith-Waterman score: 967; 44.6% identity (71.7% similar) in 361 aa overlap (279-632:227-567)
250 260 270 280 290 300
pF1KE1 RQPCQVLWLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEP
:. . . ...:.: ::::..: . :
XP_011 LSTWSEEPGLDNPAFEESAGADTTQQPLSLPEGEITTIEIHRSNPYIQLGISIVGGNETP
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE1 GVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRVHLVVSRQV
..:.. : :: : . .. :.:: :. ...::: .::.:...:
XP_011 ---LINIVIQEV-YRDGVIARDGRLLA--------GD-----QILQASGERVNLTIARPG
260 270 280 290
370 380 390 400 410 420
pF1KE1 RQRSPDIFQEAGWNSNGSW--SPGPG-ERSNTPKPLHPTITCHEKVVNIQKDPGESLGMT
. . . ..::: .:..: .: : : .. : : .::.:: ....:.: ::::::
XP_011 KPQPGNTIREAGNHSSSSQHHTPPPYYSRPSSHKDLTQCVTCQEKHITVKKEPHESLGMT
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE1 VAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVALLKRT
:::: . . .:::.: :: : : ..:::::: ::.:::..:..::..:.:::::.:: .
XP_011 VAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKAS
360 370 380 390 400 410
490 500 510 520 530 540
pF1KE1 SSS--IVLKALEVK--EYEPQEDCSSPAALDSNHNMAPPSDWSPSWVMWLELPRCLYNCK
..: ..::::::. : :. .:.... :. : .::::::::: :: :..:.
XP_011 AASPAVALKALEVQIVEEATQNAEEQPSTFSENEYDA---SWSPSWVMWLGLPSTLHSCH
420 430 440 450 460 470
550 560 570 580 590 600
pF1KE1 DIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRST
::::::. :: :: ::::::: . :.:::::.:: ::::: :::..:::...:::: ::
XP_011 DIVLRRSYLGSWGFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLST
480 490 500 510 520 530
610 620 630
pF1KE1 SGMIHACLARLLKELKGRITLTIVSWPGTFL
:: :. :. .::: ....:::.. :::...
XP_011 VGMSHSALVPMLKEQRNKVTLTVICWPGSLV
540 550 560
>>XP_016870743 (OMIM: 603785,615219) PREDICTED: multiple (2000 aa)
initn: 731 init1: 209 opt: 743 Z-score: 576.6 bits: 118.5 E(85289): 2.2e-25
Smith-Waterman score: 747; 31.9% identity (62.1% similar) in 496 aa overlap (154-626:1533-2000)
130 140 150 160 170 180
pF1KE1 SFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVF---PRLYHLIPDGEITSIK
:. ...: .: : .:: : :.:.
XP_016 AAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATCPIIPGCE-TTIE
1510 1520 1530 1540 1550 1560
190 200 210 220 230 240
pF1KE1 INRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVP
:.. . .::: ::::.: : :::...:..:. .:::: :: ::.:::.:. ..
XP_016 ISKGRTGLGLSI--VGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKAT
1570 1580 1590 1600 1610
250 260 270 280 290 300
pF1KE1 HNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIK
:. :. .::: : . ::..:. .:: . :.. . :.:. : . ::..
XP_016 HDEAINVLRQTPQRVRLTLYRD---------EAPYKEEEVCDTLTIELQKK-PGKGLGLS
1620 1630 1640 1650 1660
310 320 330 340 350 360
pF1KE1 LVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRV
.: : .. :::. ... ::.: :.: ..:..: .::.:.: .. :..: :.. : :
XP_016 IVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTV
1670 1680 1690 1700 1710 1720
370 380 390 400
pF1KE1 HLVVSRQVR------QRSPDIFQEAGWNSNGSWS-PGPG-------ERSNTPKPLHPTIT
: :.: .. .: :. .... .: .:.. : : : :. . : :
XP_016 TLEVGR-IKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQ
1730 1740 1750 1760 1770 1780
410 420 430 440 450 460
pF1KE1 CHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVD
..:...: : .:::...:::.. :.::.. ..: :: .. ....:: ....
XP_016 -GLRTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTIC
1790 1800 1810 1820 1830 1840
470 480 490 500 510 520
pF1KE1 GVELTEVSRSEAVALLKRTSSSIVLKALE-----VKEYEPQEDCSSPAALDS-NHNMAPP
:. .....:: ::: .:.:: .... : . :: :: .. . . .
XP_016 GTSTEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQ
1850 1860 1870 1880 1890 1900
530 540 550 560 570 580
pF1KE1 SDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTP
.: .: :.: :.:.:.:. : ::: ::::: .:. :...:..
XP_016 DDLGP--------PQC----KSITLERGPDG-LGFSIVGGYGSPHGDLPIYVKTVFAKGA
1910 1920 1930 1940 1950
590 600 610 620 630
pF1KE1 AYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL
: .:::.. :: ..::::.: :. : . .::. :: .:: ..:
XP_016 ASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVLS
1960 1970 1980 1990 2000
>>XP_016870744 (OMIM: 603785,615219) PREDICTED: multiple (2000 aa)
initn: 731 init1: 209 opt: 743 Z-score: 576.6 bits: 118.5 E(85289): 2.2e-25
Smith-Waterman score: 747; 31.9% identity (62.1% similar) in 496 aa overlap (154-626:1533-2000)
130 140 150 160 170 180
pF1KE1 SFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVF---PRLYHLIPDGEITSIK
:. ...: .: : .:: : :.:.
XP_016 AAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATCPIIPGCE-TTIE
1510 1520 1530 1540 1550 1560
190 200 210 220 230 240
pF1KE1 INRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVP
:.. . .::: ::::.: : :::...:..:. .:::: :: ::.:::.:. ..
XP_016 ISKGRTGLGLSI--VGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKAT
1570 1580 1590 1600 1610
250 260 270 280 290 300
pF1KE1 HNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIK
:. :. .::: : . ::..:. .:: . :.. . :.:. : . ::..
XP_016 HDEAINVLRQTPQRVRLTLYRD---------EAPYKEEEVCDTLTIELQKK-PGKGLGLS
1620 1630 1640 1650 1660
310 320 330 340 350 360
pF1KE1 LVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRV
.: : .. :::. ... ::.: :.: ..:..: .::.:.: .. :..: :.. : :
XP_016 IVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTV
1670 1680 1690 1700 1710 1720
370 380 390 400
pF1KE1 HLVVSRQVR------QRSPDIFQEAGWNSNGSWS-PGPG-------ERSNTPKPLHPTIT
: :.: .. .: :. .... .: .:.. : : : :. . : :
XP_016 TLEVGR-IKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQ
1730 1740 1750 1760 1770 1780
410 420 430 440 450 460
pF1KE1 CHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVD
..:...: : .:::...:::.. :.::.. ..: :: .. ....:: ....
XP_016 -GLRTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTIC
1790 1800 1810 1820 1830 1840
470 480 490 500 510 520
pF1KE1 GVELTEVSRSEAVALLKRTSSSIVLKALE-----VKEYEPQEDCSSPAALDS-NHNMAPP
:. .....:: ::: .:.:: .... : . :: :: .. . . .
XP_016 GTSTEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQ
1850 1860 1870 1880 1890 1900
530 540 550 560 570 580
pF1KE1 SDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTP
.: .: :.: :.:.:.:. : ::: ::::: .:. :...:..
XP_016 DDLGP--------PQC----KSITLERGPDG-LGFSIVGGYGSPHGDLPIYVKTVFAKGA
1910 1920 1930 1940 1950
590 600 610 620 630
pF1KE1 AYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL
: .:::.. :: ..::::.: :. : . .::. :: .:: ..:
XP_016 ASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVLS
1960 1970 1980 1990 2000
>>XP_005251680 (OMIM: 603785,615219) PREDICTED: multiple (2000 aa)
initn: 731 init1: 209 opt: 743 Z-score: 576.6 bits: 118.5 E(85289): 2.2e-25
Smith-Waterman score: 747; 31.9% identity (62.1% similar) in 496 aa overlap (154-626:1533-2000)
130 140 150 160 170 180
pF1KE1 SFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVF---PRLYHLIPDGEITSIK
:. ...: .: : .:: : :.:.
XP_005 AAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATCPIIPGCE-TTIE
1510 1520 1530 1540 1550 1560
190 200 210 220 230 240
pF1KE1 INRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVP
:.. . .::: ::::.: : :::...:..:. .:::: :: ::.:::.:. ..
XP_005 ISKGRTGLGLSI--VGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKAT
1570 1580 1590 1600 1610
250 260 270 280 290 300
pF1KE1 HNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIK
:. :. .::: : . ::..:. .:: . :.. . :.:. : . ::..
XP_005 HDEAINVLRQTPQRVRLTLYRD---------EAPYKEEEVCDTLTIELQKK-PGKGLGLS
1620 1630 1640 1650 1660
310 320 330 340 350 360
pF1KE1 LVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRV
.: : .. :::. ... ::.: :.: ..:..: .::.:.: .. :..: :.. : :
XP_005 IVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTV
1670 1680 1690 1700 1710 1720
370 380 390 400
pF1KE1 HLVVSRQVR------QRSPDIFQEAGWNSNGSWS-PGPG-------ERSNTPKPLHPTIT
: :.: .. .: :. .... .: .:.. : : : :. . : :
XP_005 TLEVGR-IKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQ
1730 1740 1750 1760 1770 1780
410 420 430 440 450 460
pF1KE1 CHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVD
..:...: : .:::...:::.. :.::.. ..: :: .. ....:: ....
XP_005 -GLRTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTIC
1790 1800 1810 1820 1830 1840
470 480 490 500 510 520
pF1KE1 GVELTEVSRSEAVALLKRTSSSIVLKALE-----VKEYEPQEDCSSPAALDS-NHNMAPP
:. .....:: ::: .:.:: .... : . :: :: .. . . .
XP_005 GTSTEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQ
1850 1860 1870 1880 1890 1900
530 540 550 560 570 580
pF1KE1 SDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTP
.: .: :.: :.:.:.:. : ::: ::::: .:. :...:..
XP_005 DDLGP--------PQC----KSITLERGPDG-LGFSIVGGYGSPHGDLPIYVKTVFAKGA
1910 1920 1930 1940 1950
590 600 610 620 630
pF1KE1 AYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL
: .:::.. :: ..::::.: :. : . .::. :: .:: ..:
XP_005 ASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVLS
1960 1970 1980 1990 2000
632 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:17:53 2016 done: Sun Nov 6 22:17:55 2016
Total Scan time: 11.270 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]