Result of FASTA (omim) for
pFN21AE1539
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1539, 313 aa
1>>>pF1KE1539 313 - 313 aa - 313 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2706+/-0.000304; mu= 17.0620+/- 0.019
mean_var=75.3080+/-15.139, 0's: 0 Z-trim(117.3): 11 B-trim: 0 in 0/55
Lambda= 0.147793
statistics sampled from 29120 (29131) to 29120 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.342), width: 16
Scan time: 8.220
The best scores are: opt bits E(85289)
NP_055288 (OMIM: 612499) probable dimethyladenosin ( 313) 2067 449.6 3.8e-126
XP_011541625 (OMIM: 612499) PREDICTED: probable di ( 160) 1066 235.9 4e-62
XP_005267063 (OMIM: 607033) PREDICTED: dimethylade ( 251) 186 48.5 1.7e-05
XP_016866406 (OMIM: 607033) PREDICTED: dimethylade ( 251) 186 48.5 1.7e-05
XP_011534175 (OMIM: 607033) PREDICTED: dimethylade ( 251) 186 48.5 1.7e-05
NP_057104 (OMIM: 607033) dimethyladenosine transfe ( 346) 186 48.6 2.2e-05
XP_011534172 (OMIM: 607033) PREDICTED: dimethylade ( 267) 167 44.4 0.0003
XP_011534174 (OMIM: 607033) PREDICTED: dimethylade ( 267) 167 44.4 0.0003
XP_011534173 (OMIM: 607033) PREDICTED: dimethylade ( 267) 167 44.4 0.0003
>>NP_055288 (OMIM: 612499) probable dimethyladenosine tr (313 aa)
initn: 2067 init1: 2067 opt: 2067 Z-score: 2385.7 bits: 449.6 E(85289): 3.8e-126
Smith-Waterman score: 2067; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313)
10 20 30 40 50 60
pF1KE1 MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIR
250 260 270 280 290 300
310
pF1KE1 LLHGFNAEGIHFS
:::::::::::::
NP_055 LLHGFNAEGIHFS
310
>>XP_011541625 (OMIM: 612499) PREDICTED: probable dimeth (160 aa)
initn: 1066 init1: 1066 opt: 1066 Z-score: 1236.3 bits: 235.9 E(85289): 4e-62
Smith-Waterman score: 1066; 100.0% identity (100.0% similar) in 160 aa overlap (154-313:1-160)
130 140 150 160 170 180
pF1KE1 TCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLA
::::::::::::::::::::::::::::::
XP_011 MFQREFALRLVAKPGDKLYCRLSINTQLLA
10 20 30
190 200 210 220 230 240
pF1KE1 RVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFK
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE1 SSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLH
100 110 120 130 140 150
310
pF1KE1 GFNAEGIHFS
::::::::::
XP_011 GFNAEGIHFS
160
>>XP_005267063 (OMIM: 607033) PREDICTED: dimethyladenosi (251 aa)
initn: 166 init1: 141 opt: 186 Z-score: 219.5 bits: 48.5 E(85289): 1.7e-05
Smith-Waterman score: 189; 33.3% identity (58.9% similar) in 129 aa overlap (98-215:13-141)
70 80 90 100 110 120
pF1KE1 GNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKT---DLPFFDT
:.: .. :.. .. :: : :
XP_005 MLSDAAPGKLRIVHGDVLTFKVEKAFSESLKRPWEDDPPNVH
10 20 30 40
130 140 150 160 170
pF1KE1 CVANLPYQISSPFVFKLLLH---R--PFF--RCAI-LMFQREFALRLVAKPGDKLYCRLS
..:::...:.:...: : . : :: : . : ::.: : ::.:. :.: :::
XP_005 IIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLS
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE1 INTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNK
. .: : : :.. . . : : :.:. .::.. : :
XP_005 VMAQYLCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPKIEQPFKLVEKVVQNVFQFRR
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE1 TLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDID
XP_005 KYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISHFKSLCDVYRKMCDEDPQL
170 180 190 200 210 220
>>XP_016866406 (OMIM: 607033) PREDICTED: dimethyladenosi (251 aa)
initn: 166 init1: 141 opt: 186 Z-score: 219.5 bits: 48.5 E(85289): 1.7e-05
Smith-Waterman score: 189; 33.3% identity (58.9% similar) in 129 aa overlap (98-215:13-141)
70 80 90 100 110 120
pF1KE1 GNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKT---DLPFFDT
:.: .. :.. .. :: : :
XP_016 MLSDAAPGKLRIVHGDVLTFKVEKAFSESLKRPWEDDPPNVH
10 20 30 40
130 140 150 160 170
pF1KE1 CVANLPYQISSPFVFKLLLH---R--PFF--RCAI-LMFQREFALRLVAKPGDKLYCRLS
..:::...:.:...: : . : :: : . : ::.: : ::.:. :.: :::
XP_016 IIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLS
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE1 INTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNK
. .: : : :.. . . : : :.:. .::.. : :
XP_016 VMAQYLCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPKIEQPFKLVEKVVQNVFQFRR
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE1 TLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDID
XP_016 KYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISHFKSLCDVYRKMCDEDPQL
170 180 190 200 210 220
>>XP_011534175 (OMIM: 607033) PREDICTED: dimethyladenosi (251 aa)
initn: 166 init1: 141 opt: 186 Z-score: 219.5 bits: 48.5 E(85289): 1.7e-05
Smith-Waterman score: 189; 33.3% identity (58.9% similar) in 129 aa overlap (98-215:13-141)
70 80 90 100 110 120
pF1KE1 GNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKT---DLPFFDT
:.: .. :.. .. :: : :
XP_011 MLSDAAPGKLRIVHGDVLTFKVEKAFSESLKRPWEDDPPNVH
10 20 30 40
130 140 150 160 170
pF1KE1 CVANLPYQISSPFVFKLLLH---R--PFF--RCAI-LMFQREFALRLVAKPGDKLYCRLS
..:::...:.:...: : . : :: : . : ::.: : ::.:. :.: :::
XP_011 IIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLS
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE1 INTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNK
. .: : : :.. . . : : :.:. .::.. : :
XP_011 VMAQYLCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPKIEQPFKLVEKVVQNVFQFRR
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE1 TLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDID
XP_011 KYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISHFKSLCDVYRKMCDEDPQL
170 180 190 200 210 220
>>NP_057104 (OMIM: 607033) dimethyladenosine transferase (346 aa)
initn: 211 init1: 141 opt: 186 Z-score: 217.5 bits: 48.6 E(85289): 2.2e-05
Smith-Waterman score: 264; 30.0% identity (59.1% similar) in 220 aa overlap (20-215:19-236)
10 20 30 40 50 60
pF1KE1 MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVV
::. . :. ..:..: . . ..:. ::. . :
NP_057 MAASGKLSTCRLPPLPTIREIIKLLRLQAAKQLSQNFLLDLRLTDKIVRKAGNLTNAYV
10 20 30 40 50
70 80 90 100 110
pF1KE1 LEVGPGTGNMTVKLLEK-AKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVL--KT
::::: :..: ..:. . .... : : :.. :. ...: .::... :::: :.
NP_057 YEVGPGPGGITRSILNADVAELLVVEKDTRFIPGLQMLSDAAP--GKLRIVHGDVLTFKV
60 70 80 90 100 110
120 130 140 150
pF1KE1 DLPFFDTC-------------VANLPYQISSPFVFKLLLH---R--PFF--RCAI-LMFQ
. : .. ..:::...:.:...: : . : :: : . : ::
NP_057 EKAFSESLKRPWEDDPPNVHIIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE1 REFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPP
.: : ::.:. :.: :::. .: : : :.. . . : : :.:. .::.. : :
NP_057 KEVAERLAANTGSKQRSRLSVMAQYLCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPK
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 PINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKI
NP_057 IEQPFKLVEKVVQNVFQFRRKYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSI
240 250 260 270 280 290
>>XP_011534172 (OMIM: 607033) PREDICTED: dimethyladenosi (267 aa)
initn: 167 init1: 97 opt: 167 Z-score: 197.2 bits: 44.4 E(85289): 0.0003
Smith-Waterman score: 245; 28.5% identity (57.9% similar) in 221 aa overlap (20-216:19-237)
10 20 30 40 50 60
pF1KE1 MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVV
::. . :. ..:..: . . ..:. ::. . :
XP_011 MAASGKLSTCRLPPLPTIREIIKLLRLQAAKQLSQNFLLDLRLTDKIVRKAGNLTNAYV
10 20 30 40 50
70 80 90 100 110
pF1KE1 LEVGPGTGNMTVKLLEK-AKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVL--KT
::::: :..: ..:. . .... : : :.. :. ...: .::... :::: :.
XP_011 YEVGPGPGGITRSILNADVAELLVVEKDTRFIPGLQMLSDAAP--GKLRIVHGDVLTFKV
60 70 80 90 100 110
120 130 140 150
pF1KE1 DLPFFDTC-------------VANLPYQISSPFVFKLLLH---R--PFF--RCAI-LMFQ
. : .. ..:::...:.:...: : . : :: : . : ::
XP_011 EKAFSESLKRPWEDDPPNVHIIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE1 REFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPP
.: : ::.:. :.: :::. .: : : :.. . . : : :.. . ..: . :
XP_011 KEVAERLAANTGSKQRSRLSVMAQYLCNVRHIFTIPGQAFVPKPEIFLHLNCLHPLSGAP
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 PINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKI
XP_011 LWGRGDSVDPILQPPLQFCPFLGRNRSWGT
240 250 260
>>XP_011534174 (OMIM: 607033) PREDICTED: dimethyladenosi (267 aa)
initn: 167 init1: 97 opt: 167 Z-score: 197.2 bits: 44.4 E(85289): 0.0003
Smith-Waterman score: 245; 28.5% identity (57.9% similar) in 221 aa overlap (20-216:19-237)
10 20 30 40 50 60
pF1KE1 MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVV
::. . :. ..:..: . . ..:. ::. . :
XP_011 MAASGKLSTCRLPPLPTIREIIKLLRLQAAKQLSQNFLLDLRLTDKIVRKAGNLTNAYV
10 20 30 40 50
70 80 90 100 110
pF1KE1 LEVGPGTGNMTVKLLEK-AKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVL--KT
::::: :..: ..:. . .... : : :.. :. ...: .::... :::: :.
XP_011 YEVGPGPGGITRSILNADVAELLVVEKDTRFIPGLQMLSDAAP--GKLRIVHGDVLTFKV
60 70 80 90 100 110
120 130 140 150
pF1KE1 DLPFFDTC-------------VANLPYQISSPFVFKLLLH---R--PFF--RCAI-LMFQ
. : .. ..:::...:.:...: : . : :: : . : ::
XP_011 EKAFSESLKRPWEDDPPNVHIIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE1 REFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPP
.: : ::.:. :.: :::. .: : : :.. . . : : :.. . ..: . :
XP_011 KEVAERLAANTGSKQRSRLSVMAQYLCNVRHIFTIPGQAFVPKPEIFLHLNCLHPLSGAP
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 PINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKI
XP_011 LWGRGDSVDPILQPPLQFCPFLGRNRSWGT
240 250 260
>>XP_011534173 (OMIM: 607033) PREDICTED: dimethyladenosi (267 aa)
initn: 167 init1: 97 opt: 167 Z-score: 197.2 bits: 44.4 E(85289): 0.0003
Smith-Waterman score: 245; 28.5% identity (57.9% similar) in 221 aa overlap (20-216:19-237)
10 20 30 40 50 60
pF1KE1 MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVV
::. . :. ..:..: . . ..:. ::. . :
XP_011 MAASGKLSTCRLPPLPTIREIIKLLRLQAAKQLSQNFLLDLRLTDKIVRKAGNLTNAYV
10 20 30 40 50
70 80 90 100 110
pF1KE1 LEVGPGTGNMTVKLLEK-AKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVL--KT
::::: :..: ..:. . .... : : :.. :. ...: .::... :::: :.
XP_011 YEVGPGPGGITRSILNADVAELLVVEKDTRFIPGLQMLSDAAP--GKLRIVHGDVLTFKV
60 70 80 90 100 110
120 130 140 150
pF1KE1 DLPFFDTC-------------VANLPYQISSPFVFKLLLH---R--PFF--RCAI-LMFQ
. : .. ..:::...:.:...: : . : :: : . : ::
XP_011 EKAFSESLKRPWEDDPPNVHIIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE1 REFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPP
.: : ::.:. :.: :::. .: : : :.. . . : : :.. . ..: . :
XP_011 KEVAERLAANTGSKQRSRLSVMAQYLCNVRHIFTIPGQAFVPKPEIFLHLNCLHPLSGAP
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 PINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKI
XP_011 LWGRGDSVDPILQPPLQFCPFLGRNRSWGT
240 250 260
313 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:53:24 2016 done: Mon Nov 7 01:53:25 2016
Total Scan time: 8.220 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]