Result of FASTA (omim) for
pFN21AE1530
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1530, 446 aa
1>>>pF1KE1530 446 - 446 aa - 446 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9783+/-0.000383; mu= 19.5821+/- 0.024
mean_var=69.1907+/-13.681, 0's: 0 Z-trim(112.7): 63 B-trim: 0 in 0/54
Lambda= 0.154188
statistics sampled from 21617 (21680) to 21617 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.254), width: 16
Scan time: 6.480
The best scores are: opt bits E(85289)
NP_115914 (OMIM: 615103) tubulin beta-6 chain isof ( 446) 3006 678.0 1.4e-194
NP_001290453 (OMIM: 615103) tubulin beta-6 chain i ( 446) 3006 678.0 1.4e-194
NP_006077 (OMIM: 600638,602661,614039) tubulin bet ( 450) 2810 634.4 1.9e-181
NP_006078 (OMIM: 602662) tubulin beta-4A chain iso ( 444) 2776 626.8 3.5e-179
NP_001276058 (OMIM: 602662) tubulin beta-4A chain ( 444) 2776 626.8 3.5e-179
NP_001276056 (OMIM: 602662) tubulin beta-4A chain ( 489) 2776 626.8 3.7e-179
NP_001276052 (OMIM: 602662) tubulin beta-4A chain ( 495) 2776 626.8 3.8e-179
NP_821080 (OMIM: 610031,612850) tubulin beta-2B ch ( 445) 2760 623.2 4.1e-178
NP_006079 (OMIM: 602660) tubulin beta-4B chain [Ho ( 445) 2754 621.9 1e-177
NP_001060 (OMIM: 615101,615763) tubulin beta-2A ch ( 445) 2745 619.9 4.1e-177
NP_821133 (OMIM: 156610,191130,615771) tubulin bet ( 444) 2741 619.0 7.6e-177
NP_001280141 (OMIM: 156610,191130,615771) tubulin ( 464) 2621 592.3 8.6e-169
NP_817124 (OMIM: 616768,616780) tubulin beta-8 cha ( 444) 2614 590.8 2.4e-168
NP_001290456 (OMIM: 615103) tubulin beta-6 chain i ( 374) 2520 569.8 4.2e-162
NP_001280143 (OMIM: 156610,191130,615771) tubulin ( 400) 2422 548.0 1.6e-155
NP_110400 (OMIM: 612901,613112) tubulin beta-1 cha ( 451) 2414 546.3 6.1e-155
NP_001290457 (OMIM: 615103) tubulin beta-6 chain i ( 381) 2378 538.2 1.4e-152
NP_001184110 (OMIM: 600638,602661,614039) tubulin ( 378) 2370 536.4 4.7e-152
NP_001290455 (OMIM: 615103) tubulin beta-6 chain i ( 409) 2368 536.0 6.8e-152
NP_001276059 (OMIM: 602662) tubulin beta-4A chain ( 372) 2361 534.4 1.9e-151
NP_001276060 (OMIM: 602662) tubulin beta-4A chain ( 372) 2361 534.4 1.9e-151
NP_001280145 (OMIM: 156610,191130,615771) tubulin ( 372) 2328 527.1 3e-149
NP_001280144 (OMIM: 156610,191130,615771) tubulin ( 372) 2328 527.1 3e-149
XP_016883574 (OMIM: 612901,613112) PREDICTED: tubu ( 429) 2265 513.1 5.6e-145
XP_011517761 (OMIM: 616768,616780) PREDICTED: tubu ( 372) 2229 505.1 1.3e-142
NP_001297244 (OMIM: 615101,615763) tubulin beta-2A ( 360) 2179 493.9 2.8e-139
NP_001290458 (OMIM: 615103) tubulin beta-6 chain i ( 300) 1991 452.1 9.4e-127
NP_001290459 (OMIM: 615103) tubulin beta-6 chain i ( 300) 1991 452.1 9.4e-127
XP_016871682 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 1953 443.6 3.6e-124
XP_016871681 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 1953 443.6 3.6e-124
XP_011517762 (OMIM: 616768,616780) PREDICTED: tubu ( 291) 1592 363.3 4.8e-100
NP_005991 (OMIM: 191110,616208) tubulin alpha-4A c ( 448) 1280 294.0 5.2e-79
NP_006073 (OMIM: 602530) tubulin alpha-1B chain [H ( 451) 1274 292.7 1.3e-78
NP_006000 (OMIM: 602529,611603) tubulin alpha-1A c ( 451) 1266 290.9 4.6e-78
NP_001257328 (OMIM: 602529,611603) tubulin alpha-1 ( 451) 1266 290.9 4.6e-78
NP_005992 (OMIM: 602528) tubulin alpha-3C/D chain ( 450) 1256 288.7 2.1e-77
NP_061816 (OMIM: 605742,613180) tubulin alpha-8 ch ( 449) 1235 284.0 5.4e-76
NP_001265481 (OMIM: 191110,616208) tubulin alpha-4 ( 433) 1228 282.5 1.5e-75
NP_001257329 (OMIM: 602529,611603) tubulin alpha-1 ( 416) 1157 266.6 8.5e-71
NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 ( 383) 1091 251.9 2.1e-66
NP_001061 (OMIM: 191135,615412) tubulin gamma-1 ch ( 451) 1003 232.4 1.9e-60
NP_057521 (OMIM: 605785) tubulin gamma-2 chain iso ( 451) 994 230.4 7.5e-60
XP_016860313 (OMIM: 191110,616208) PREDICTED: tubu ( 295) 788 184.4 3.4e-46
NP_001280142 (OMIM: 156610,191130,615771) tubulin ( 242) 754 176.8 5.4e-44
NP_001290454 (OMIM: 615103) tubulin beta-6 chain i ( 104) 634 149.8 3.1e-36
NP_001307438 (OMIM: 605785) tubulin gamma-2 chain ( 460) 630 149.5 1.8e-35
XP_016879942 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 526 126.2 1.2e-28
XP_011522916 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 526 126.2 1.2e-28
NP_057346 (OMIM: 607345) tubulin epsilon chain [Ho ( 475) 517 124.3 6.8e-28
XP_016879943 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 490 118.1 2.9e-26
>>NP_115914 (OMIM: 615103) tubulin beta-6 chain isoform (446 aa)
initn: 3006 init1: 3006 opt: 3006 Z-score: 3614.4 bits: 678.0 E(85289): 1.4e-194
Smith-Waterman score: 3006; 100.0% identity (100.0% similar) in 446 aa overlap (1-446:1-446)
10 20 30 40 50 60
pF1KE1 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
430 440
pF1KE1 EYQQYQDATANDGEEAFEDEEEEIDG
::::::::::::::::::::::::::
NP_115 EYQQYQDATANDGEEAFEDEEEEIDG
430 440
>>NP_001290453 (OMIM: 615103) tubulin beta-6 chain isofo (446 aa)
initn: 3006 init1: 3006 opt: 3006 Z-score: 3614.4 bits: 678.0 E(85289): 1.4e-194
Smith-Waterman score: 3006; 100.0% identity (100.0% similar) in 446 aa overlap (1-446:1-446)
10 20 30 40 50 60
pF1KE1 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
430 440
pF1KE1 EYQQYQDATANDGEEAFEDEEEEIDG
::::::::::::::::::::::::::
NP_001 EYQQYQDATANDGEEAFEDEEEEIDG
430 440
>>NP_006077 (OMIM: 600638,602661,614039) tubulin beta-3 (450 aa)
initn: 2810 init1: 2810 opt: 2810 Z-score: 3378.8 bits: 634.4 E(85289): 1.9e-181
Smith-Waterman score: 2810; 93.0% identity (98.4% similar) in 443 aa overlap (1-443:1-443)
10 20 30 40 50 60
pF1KE1 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
:::::::::::::::::.::::::::::::::.:.::::: ::::::.:::::.::.:::
NP_006 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
::: ::::::::::::::: ::.:::::::::::.:::::::::::::::::::.:::::
NP_006 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
:::::.::::::::::::::::::::::::::::.:::.::::::::::.::::::::::
NP_006 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
::::::::.::::::::::::::::::::::::::::.::::::::::::::::::::::
NP_006 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::.:::
NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_006 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
:::.:::::::::::::::::::::.:::::::::::.::::::::::::::::::::::
NP_006 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
430 440
pF1KE1 EYQQYQDATANDGEEAFEDEEEEIDG
::::::::::.. : .::.:::
NP_006 EYQQYQDATAEEEGEMYEDDEEESEAQGPK
430 440 450
>>NP_006078 (OMIM: 602662) tubulin beta-4A chain isoform (444 aa)
initn: 2772 init1: 2772 opt: 2776 Z-score: 3338.0 bits: 626.8 E(85289): 3.5e-179
Smith-Waterman score: 2776; 92.3% identity (97.5% similar) in 443 aa overlap (1-443:1-441)
10 20 30 40 50 60
pF1KE1 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
::::::.::::::::::.::::::::::::::.: : ::: ::::::::::::... .::
NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
:::.:::::::::::::::::::.::::::.:::.:::::::::::::::::::::::::
NP_006 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
::: : :::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_006 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_006 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
::::::::::::::.:::: :::::::::::..:::::::::::::::::.:::::::::
NP_006 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
::::.::::::::::::::::::::.:::::::::::.::::::::::::::::::::::
NP_006 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
430 440
pF1KE1 EYQQYQDATANDGEEAFEDEEEEIDG
::::::::::..:: ::.: ::
NP_006 EYQQYQDATAEEGE--FEEEAEEEVA
430 440
>>NP_001276058 (OMIM: 602662) tubulin beta-4A chain isof (444 aa)
initn: 2772 init1: 2772 opt: 2776 Z-score: 3338.0 bits: 626.8 E(85289): 3.5e-179
Smith-Waterman score: 2776; 92.3% identity (97.5% similar) in 443 aa overlap (1-443:1-441)
10 20 30 40 50 60
pF1KE1 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
::::::.::::::::::.::::::::::::::.: : ::: ::::::::::::... .::
NP_001 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
:::.:::::::::::::::::::.::::::.:::.:::::::::::::::::::::::::
NP_001 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
::: : :::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_001 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
::::::::::::::.:::: :::::::::::..:::::::::::::::::.:::::::::
NP_001 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
::::.::::::::::::::::::::.:::::::::::.::::::::::::::::::::::
NP_001 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
430 440
pF1KE1 EYQQYQDATANDGEEAFEDEEEEIDG
::::::::::..:: ::.: ::
NP_001 EYQQYQDATAEEGE--FEEEAEEEVA
430 440
>>NP_001276056 (OMIM: 602662) tubulin beta-4A chain isof (489 aa)
initn: 2772 init1: 2772 opt: 2776 Z-score: 3337.4 bits: 626.8 E(85289): 3.7e-179
Smith-Waterman score: 2776; 92.3% identity (97.5% similar) in 443 aa overlap (1-443:46-486)
10 20 30
pF1KE1 MREIVHIQAGQCGNQIGTKFWEVISDEHGI
::::::.::::::::::.::::::::::::
NP_001 AVSAASSTLAAAAAPRARATAAASTLSATAMREIVHLQAGQCGNQIGAKFWEVISDEHGI
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 DPAGGYVGDSALQLERINVYYNESSSQKYVPRAALVDLEPGTMDSVRSGPFGQLFRPDNF
::.: : ::: ::::::::::::... .:::::.:::::::::::::::::::.::::::
NP_001 DPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 IFGQTGAGNNWAKGHYTEGAELVDAVLDVVRKECEHCDCLQGFQLTHSLGGGTGSGMGTL
.:::.:::::::::::::::::::::::::::: : ::::::::::::::::::::::::
NP_001 VFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE1 LISKIREEFPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
NP_001 LISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE1 CFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_001 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE1 APLTSRGSQQYRALTVPELTQQMFDARNMMAACDPRHGRYLTVATVFRGPMSMKEVDEQM
::::::::::::::::::::::::::.:::::::::::::::::.:::: ::::::::::
NP_001 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE1 LAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMASTFIGNSTAIQELFKRISEQFSAMFR
:..:::::::::::::::::.:::::::::::::.::::::::::::::::::::.::::
NP_001 LSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR
380 390 400 410 420 430
400 410 420 430 440
pF1KE1 RKAFLHWFTGEGMDEMEFTEAESNMNDLVSEYQQYQDATANDGEEAFEDEEEEIDG
:::::::.::::::::::::::::::::::::::::::::..:: ::.: ::
NP_001 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGE--FEEEAEEEVA
440 450 460 470 480
>>NP_001276052 (OMIM: 602662) tubulin beta-4A chain isof (495 aa)
initn: 2772 init1: 2772 opt: 2776 Z-score: 3337.3 bits: 626.8 E(85289): 3.8e-179
Smith-Waterman score: 2776; 92.3% identity (97.5% similar) in 443 aa overlap (1-443:52-492)
10 20 30
pF1KE1 MREIVHIQAGQCGNQIGTKFWEVISDEHGI
::::::.::::::::::.::::::::::::
NP_001 AVSAASSTLAAAAAPRARATAAASTLSATAMREIVHLQAGQCGNQIGAKFWEVISDEHGI
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 DPAGGYVGDSALQLERINVYYNESSSQKYVPRAALVDLEPGTMDSVRSGPFGQLFRPDNF
::.: : ::: ::::::::::::... .:::::.:::::::::::::::::::.::::::
NP_001 DPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 IFGQTGAGNNWAKGHYTEGAELVDAVLDVVRKECEHCDCLQGFQLTHSLGGGTGSGMGTL
.:::.:::::::::::::::::::::::::::: : ::::::::::::::::::::::::
NP_001 VFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE1 LISKIREEFPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
NP_001 LISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE1 CFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_001 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 APLTSRGSQQYRALTVPELTQQMFDARNMMAACDPRHGRYLTVATVFRGPMSMKEVDEQM
::::::::::::::::::::::::::.:::::::::::::::::.:::: ::::::::::
NP_001 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE1 LAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMASTFIGNSTAIQELFKRISEQFSAMFR
:..:::::::::::::::::.:::::::::::::.::::::::::::::::::::.::::
NP_001 LSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR
390 400 410 420 430 440
400 410 420 430 440
pF1KE1 RKAFLHWFTGEGMDEMEFTEAESNMNDLVSEYQQYQDATANDGEEAFEDEEEEIDG
:::::::.::::::::::::::::::::::::::::::::..:: ::.: ::
NP_001 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGE--FEEEAEEEVA
450 460 470 480 490
>>NP_821080 (OMIM: 610031,612850) tubulin beta-2B chain (445 aa)
initn: 2740 init1: 2740 opt: 2760 Z-score: 3318.7 bits: 623.2 E(85289): 4.1e-178
Smith-Waterman score: 2760; 91.4% identity (97.3% similar) in 443 aa overlap (1-443:1-442)
10 20 30 40 50 60
pF1KE1 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
:::::::::::::::::.::::::::::::::.:.: ::: ::::::::::::....:::
NP_821 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
::: :::::::::::::::::::.::::::.:::.:::::::::::::::::::.:::::
NP_821 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
::: : ::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_821 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_821 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::..:::
NP_821 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
::::::::::::::..::: ::::::::::: .:.:::::::::::::::.:::::::::
NP_821 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
:::..::::::::::::::::::::.:::::::::::.::::::::::::::::::::::
NP_821 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
430 440
pF1KE1 EYQQYQDATANDGEEAFEDEEEEIDG
::::::::::.. : ::.:: :
NP_821 EYQQYQDATADEQGE-FEEEEGEDEA
430 440
>>NP_006079 (OMIM: 602660) tubulin beta-4B chain [Homo s (445 aa)
initn: 2776 init1: 2754 opt: 2754 Z-score: 3311.5 bits: 621.9 E(85289): 1e-177
Smith-Waterman score: 2754; 91.4% identity (97.1% similar) in 443 aa overlap (1-443:1-442)
10 20 30 40 50 60
pF1KE1 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
::::::.::::::::::.::::::::::::::.: : ::: ::::::::::::... :::
NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
:::.:::::::::::::::::::.::::::.:::.:::::::::::::::::::.:::::
NP_006 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
::: : ::::::::::::::::::::::::::::::::.::::::::::.::::::::::
NP_006 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_006 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
::::::::::::::.:::: ::::::::::: .:.:::::::::::::::.:::::::::
NP_006 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
:::..::::::::::::::::::::.:::::::::::.::::::::::::::::::::::
NP_006 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
430 440
pF1KE1 EYQQYQDATANDGEEAFEDEEEEIDG
::::::::::.. : ::.: ::
NP_006 EYQQYQDATAEE-EGEFEEEAEEEVA
430 440
>>NP_001060 (OMIM: 615101,615763) tubulin beta-2A chain (445 aa)
initn: 2725 init1: 2725 opt: 2745 Z-score: 3300.7 bits: 619.9 E(85289): 4.1e-177
Smith-Waterman score: 2745; 91.2% identity (97.1% similar) in 443 aa overlap (1-443:1-442)
10 20 30 40 50 60
pF1KE1 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV
:::::::::::::::::.::::::::::::::.:.: ::: ::::::::::::....:::
NP_001 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV
::: :::::::::::::::::::.::::::.:::.:::::::::::::::::::.:::::
NP_001 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV
::: : ::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_001 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL
:::::::::::::::::::: ::::::::::::::::::::::::::::::::::::: :
NP_001 EPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::..:::
NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
::::::::::::::..::: ::::::::::: .:.:::::::::::::::.:::::::::
NP_001 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS
:::..::::::::::::::::::::.:::::::::::.::::::::::::::::::::::
NP_001 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
370 380 390 400 410 420
430 440
pF1KE1 EYQQYQDATANDGEEAFEDEEEEIDG
::::::::::.. : ::.:: :
NP_001 EYQQYQDATADEQGE-FEEEEGEDEA
430 440
446 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:37:45 2016 done: Mon Nov 7 02:37:46 2016
Total Scan time: 6.480 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]