Result of FASTA (omim) for
pFN21AE1521
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1521, 329 aa
1>>>pF1KE1521 329 - 329 aa - 329 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8367+/-0.000383; mu= 13.9195+/- 0.024
mean_var=92.8679+/-18.149, 0's: 0 Z-trim(116.1): 111 B-trim: 879 in 1/55
Lambda= 0.133089
statistics sampled from 26828 (26984) to 26828 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.316), width: 16
Scan time: 6.580
The best scores are: opt bits E(85289)
NP_787058 (OMIM: 601020) T-lymphocyte activation a ( 329) 2203 433.0 4.1e-121
NP_008820 (OMIM: 601020) T-lymphocyte activation a ( 323) 2153 423.4 3.1e-118
NP_001193854 (OMIM: 601020) T-lymphocyte activatio ( 247) 1658 328.3 1e-89
NP_795711 (OMIM: 601020) T-lymphocyte activation a ( 275) 1486 295.3 9.8e-80
NP_001193853 (OMIM: 601020) T-lymphocyte activatio ( 217) 1309 261.3 1.4e-69
NP_005182 (OMIM: 112203) T-lymphocyte activation a ( 288) 277 63.2 7.7e-10
XP_016863009 (OMIM: 112203) PREDICTED: T-lymphocyt ( 249) 243 56.6 6.3e-08
XP_011527816 (OMIM: 605717) PREDICTED: ICOS ligand ( 361) 242 56.5 9.6e-08
XP_011511629 (OMIM: 112203) PREDICTED: T-lymphocyt ( 217) 234 54.8 1.9e-07
NP_001316557 (OMIM: 605715) CD276 antigen isoform ( 316) 233 54.8 2.9e-07
NP_079516 (OMIM: 605715) CD276 antigen isoform b p ( 316) 233 54.8 2.9e-07
XP_011527818 (OMIM: 605717) PREDICTED: ICOS ligand ( 334) 225 53.3 8.7e-07
NP_056074 (OMIM: 605717) ICOS ligand isoform a pre ( 302) 219 52.1 1.8e-06
XP_011527817 (OMIM: 605717) PREDICTED: ICOS ligand ( 304) 219 52.1 1.8e-06
NP_001269979 (OMIM: 605717) ICOS ligand isoform b ( 309) 219 52.1 1.8e-06
XP_016883799 (OMIM: 605717) PREDICTED: ICOS ligand ( 275) 202 48.8 1.6e-05
NP_054862 (OMIM: 605402) programmed cell death 1 l ( 290) 202 48.8 1.7e-05
NP_001015887 (OMIM: 608351) immunoglobulin superfa ( 431) 200 48.5 3e-05
XP_011510772 (OMIM: 608351) PREDICTED: immunoglobu ( 430) 197 48.0 4.4e-05
NP_689751 (OMIM: 608351) immunoglobulin superfamil ( 430) 197 48.0 4.4e-05
XP_011510771 (OMIM: 608351) PREDICTED: immunoglobu ( 430) 197 48.0 4.4e-05
XP_011510770 (OMIM: 608351) PREDICTED: immunoglobu ( 443) 197 48.0 4.5e-05
XP_011510766 (OMIM: 608351) PREDICTED: immunoglobu ( 480) 197 48.0 4.8e-05
XP_011510765 (OMIM: 608351) PREDICTED: immunoglobu ( 480) 197 48.0 4.8e-05
XP_011510767 (OMIM: 608351) PREDICTED: immunoglobu ( 480) 197 48.0 4.8e-05
XP_011510764 (OMIM: 608351) PREDICTED: immunoglobu ( 481) 197 48.0 4.8e-05
NP_001723 (OMIM: 601610) butyrophilin subfamily 1 ( 526) 195 47.6 6.7e-05
XP_005249397 (OMIM: 601610) PREDICTED: butyrophili ( 626) 195 47.7 7.7e-05
XP_011510776 (OMIM: 608351) PREDICTED: immunoglobu ( 323) 186 45.8 0.00015
XP_011510769 (OMIM: 608351) PREDICTED: immunoglobu ( 453) 184 45.5 0.00026
NP_078902 (OMIM: 608162) V-set domain-containing T ( 282) 181 44.8 0.00027
XP_016857824 (OMIM: 608162) PREDICTED: V-set domai ( 287) 181 44.8 0.00027
XP_011520398 (OMIM: 605715) PREDICTED: CD276 antig ( 534) 181 45.0 0.00044
NP_001019907 (OMIM: 605715) CD276 antigen isoform ( 534) 181 45.0 0.00044
XP_016878127 (OMIM: 605715) PREDICTED: CD276 antig ( 534) 181 45.0 0.00044
XP_005254757 (OMIM: 605715) PREDICTED: CD276 antig ( 534) 181 45.0 0.00044
XP_011520397 (OMIM: 605715) PREDICTED: CD276 antig ( 534) 181 45.0 0.00044
XP_011510774 (OMIM: 608351) PREDICTED: immunoglobu ( 406) 174 43.5 0.0009
NP_001300958 (OMIM: 605402) programmed cell death ( 245) 171 42.8 0.00091
XP_011510773 (OMIM: 608351) PREDICTED: immunoglobu ( 429) 174 43.5 0.00094
XP_011510768 (OMIM: 608351) PREDICTED: immunoglobu ( 457) 174 43.6 0.00099
XP_011512570 (OMIM: 613594) PREDICTED: butyrophili ( 339) 172 43.1 0.001
XP_006715042 (OMIM: 613594) PREDICTED: butyrophili ( 339) 172 43.1 0.001
XP_006715043 (OMIM: 613594) PREDICTED: butyrophili ( 339) 172 43.1 0.001
XP_006715044 (OMIM: 613594) PREDICTED: butyrophili ( 339) 172 43.1 0.001
XP_011512569 (OMIM: 613594) PREDICTED: butyrophili ( 339) 172 43.1 0.001
XP_011512571 (OMIM: 613594) PREDICTED: butyrophili ( 297) 164 41.5 0.0027
XP_016865702 (OMIM: 613594) PREDICTED: butyrophili ( 297) 164 41.5 0.0027
XP_006715045 (OMIM: 613594) PREDICTED: butyrophili ( 297) 164 41.5 0.0027
NP_001184177 (OMIM: 613594) butyrophilin subfamily ( 311) 162 41.1 0.0036
>>NP_787058 (OMIM: 601020) T-lymphocyte activation antig (329 aa)
initn: 2203 init1: 2203 opt: 2203 Z-score: 2295.5 bits: 433.0 E(85289): 4.1e-121
Smith-Waterman score: 2203; 99.7% identity (100.0% similar) in 329 aa overlap (1-329:1-329)
10 20 30 40 50 60
pF1KE1 MDPQCTMGLSNILFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNQSLSELVVFWQDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 MDPQCTMGLSNILFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNQSLSELVVFWQDQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ENLVLNEVYLGKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCIIHHKKPTGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 ENLVLNEVYLGKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCIIHHKKPTGM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVLLRTKNSTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 IRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVLLRTKNSTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EYDGIMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPFSIELEDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 EYDGIMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPFSIELEDPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 PPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCGTNTMEREESEQTKKREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 PPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCGTNTMEREESEQTKKREK
250 260 270 280 290 300
310 320
pF1KE1 IHIPERSDETQRVFKSSKTSSCDKSDTCF
:::::::::.:::::::::::::::::::
NP_787 IHIPERSDEAQRVFKSSKTSSCDKSDTCF
310 320
>>NP_008820 (OMIM: 601020) T-lymphocyte activation antig (323 aa)
initn: 2153 init1: 2153 opt: 2153 Z-score: 2243.7 bits: 423.4 E(85289): 3.1e-118
Smith-Waterman score: 2153; 99.7% identity (100.0% similar) in 323 aa overlap (7-329:1-323)
10 20 30 40 50 60
pF1KE1 MDPQCTMGLSNILFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNQSLSELVVFWQDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MGLSNILFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNQSLSELVVFWQDQ
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 ENLVLNEVYLGKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCIIHHKKPTGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 ENLVLNEVYLGKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCIIHHKKPTGM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 IRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVLLRTKNSTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 IRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVLLRTKNSTI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 EYDGIMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPFSIELEDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 EYDGIMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPFSIELEDPQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 PPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCGTNTMEREESEQTKKREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 PPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCGTNTMEREESEQTKKREK
240 250 260 270 280 290
310 320
pF1KE1 IHIPERSDETQRVFKSSKTSSCDKSDTCF
:::::::::.:::::::::::::::::::
NP_008 IHIPERSDEAQRVFKSSKTSSCDKSDTCF
300 310 320
>>NP_001193854 (OMIM: 601020) T-lymphocyte activation an (247 aa)
initn: 1658 init1: 1658 opt: 1658 Z-score: 1731.6 bits: 328.3 E(85289): 1e-89
Smith-Waterman score: 1658; 99.6% identity (100.0% similar) in 247 aa overlap (83-329:1-247)
60 70 80 90 100 110
pF1KE1 LVVFWQDQENLVLNEVYLGKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCII
::::::::::::::::::::::::::::::
NP_001 MGRTSFDSDSWTLRLHNLQIKDKGLYQCII
10 20 30
120 130 140 150 160 170
pF1KE1 HHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVL
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE1 LRTKNSTIEYDGIMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTKNSTIEYDGIMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPF
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE1 SIELEDPQPPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCGTNTMEREES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIELEDPQPPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCGTNTMEREES
160 170 180 190 200 210
300 310 320
pF1KE1 EQTKKREKIHIPERSDETQRVFKSSKTSSCDKSDTCF
:::::::::::::::::.:::::::::::::::::::
NP_001 EQTKKREKIHIPERSDEAQRVFKSSKTSSCDKSDTCF
220 230 240
>>NP_795711 (OMIM: 601020) T-lymphocyte activation antig (275 aa)
initn: 1486 init1: 1486 opt: 1486 Z-score: 1552.5 bits: 295.3 E(85289): 9.8e-80
Smith-Waterman score: 1683; 84.8% identity (85.1% similar) in 323 aa overlap (7-329:1-275)
10 20 30 40 50 60
pF1KE1 MDPQCTMGLSNILFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNQSLSELVVFWQDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 MGLSNILFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNQSLSELVVFWQDQ
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 ENLVLNEVYLGKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCIIHHKKPTGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 ENLVLNEVYLGKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCIIHHKKPTGM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 IRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVLLRTKNSTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 IRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVLLRTKNSTI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 EYDGIMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPFSIELEDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 EYDGIMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPFSI------
180 190 200 210 220
250 260 270 280 290 300
pF1KE1 PPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCGTNTMEREESEQTKKREK
::::::::::::::::::
NP_795 ------------------------------------------GTNTMEREESEQTKKREK
230 240
310 320
pF1KE1 IHIPERSDETQRVFKSSKTSSCDKSDTCF
:::::::::.:::::::::::::::::::
NP_795 IHIPERSDEAQRVFKSSKTSSCDKSDTCF
250 260 270
>>NP_001193853 (OMIM: 601020) T-lymphocyte activation an (217 aa)
initn: 1435 init1: 1309 opt: 1309 Z-score: 1370.3 bits: 261.3 E(85289): 1.4e-69
Smith-Waterman score: 1309; 99.5% identity (100.0% similar) in 196 aa overlap (134-329:22-217)
110 120 130 140 150 160
pF1KE1 DKGLYQCIIHHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGY
::::::::::::::::::::::::::::::
NP_001 MDPQCTMGLSNILFVMAFLLSANFSQPEIVPISNITENVYINLTCSSIHGY
10 20 30 40 50
170 180 190 200 210 220
pF1KE1 PEPKKMSVLLRTKNSTIEYDGIMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEPKKMSVLLRTKNSTIEYDGIMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETD
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE1 KTRLLSSPFSIELEDPQPPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTRLLSSPFSIELEDPQPPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCG
120 130 140 150 160 170
290 300 310 320
pF1KE1 TNTMEREESEQTKKREKIHIPERSDETQRVFKSSKTSSCDKSDTCF
::::::::::::::::::::::::::.:::::::::::::::::::
NP_001 TNTMEREESEQTKKREKIHIPERSDEAQRVFKSSKTSSCDKSDTCF
180 190 200 210
>>NP_005182 (OMIM: 112203) T-lymphocyte activation antig (288 aa)
initn: 144 init1: 54 opt: 277 Z-score: 297.7 bits: 63.2 E(85289): 7.7e-10
Smith-Waterman score: 277; 25.9% identity (58.0% similar) in 274 aa overlap (12-278:24-277)
10 20 30 40
pF1KE1 MDPQCTMGLSNILFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNQ
.: .. . ::. ... .:.: : : : . .
NP_005 MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGV--IHVTKEVKEVATLSCGH-NVSVE
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 SLSELVVFWQDQENLVLNEVYLGKEKFDSVHSKYMGRTSFD-SDSWTLRLHNLQIKDKGL
:.. ..:: ....::. .. : .. .: .:: :: ... .. . :. .:.:
NP_005 ELAQTRIYWQKEKKMVLT-MMSGDM---NIWPEYKNRTIFDITNNLSIVILALRPSDEGT
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 YQCIIHHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPK
:.:.. . . .. : : . ::: :.: : : . : :. . ::. :.:::.
NP_005 YECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIR-RIICSTSGGFPEPH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 KMSVLLRTKNSTIEYDGIMQK-SQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTR
.: : .:. : ..: ::: :::: :: .:. ..:.: ...:... . :
NP_005 -LSWL---ENGE-ELNAINTTVSQDPETELYAVSSKLDF---NMTTNHSFMCLIKYGHLR
180 190 200 210 220
230 240 250 260 270 280
pF1KE1 LLSSPFSIELEDPQPPPDHI-P-WITAVLPT---VIICVMVFCLILWKWKKKKRPRNSYK
. .. :. . . ::.. : : ... . .:: ...:. . ..: ::
NP_005 V-NQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCFA---PRCRERRRNERL
230 240 250 260 270 280
290 300 310 320
pF1KE1 CGTNTMEREESEQTKKREKIHIPERSDETQRVFKSSKTSSCDKSDTCF
NP_005 RRESVRPV
>>XP_016863009 (OMIM: 112203) PREDICTED: T-lymphocyte ac (249 aa)
initn: 144 init1: 54 opt: 243 Z-score: 263.3 bits: 56.6 E(85289): 6.3e-08
Smith-Waterman score: 243; 27.5% identity (59.2% similar) in 218 aa overlap (12-227:24-225)
10 20 30 40
pF1KE1 MDPQCTMGLSNILFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNQ
.: .. . ::. ... .:.: : : : . .
XP_016 MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGV--IHVTKEVKEVATLSCGH-NVSVE
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 SLSELVVFWQDQENLVLNEVYLGKEKFDSVHSKYMGRTSFD-SDSWTLRLHNLQIKDKGL
:.. ..:: ....::. .. : .. .: .:: :: ... .. . :. .:.:
XP_016 ELAQTRIYWQKEKKMVLT-MMSGDM---NIWPEYKNRTIFDITNNLSIVILALRPSDEGT
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 YQCIIHHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPK
:.:.. . . .. : : . ::: :.: : : . : :. . ::. :.:::.
XP_016 YECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIR-RIICSTSGGFPEPH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 KMSVLLRTKNSTIEYDGIMQK-SQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTR
.: : .:. : ..: ::: :::: :: .:. ..:.: ...:... . :
XP_016 -LSWL---ENGE-ELNAINTTVSQDPETELYAVSSKLDF---NMTTNHSFMCLIKYGHLR
180 190 200 210 220
230 240 250 260 270 280
pF1KE1 LLSSPFSIELEDPQPPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCGTNT
.
XP_016 VNQTFNWNTKVNSGNHLMSPFNLVF
230 240
>>XP_011527816 (OMIM: 605717) PREDICTED: ICOS ligand iso (361 aa)
initn: 70 init1: 70 opt: 242 Z-score: 260.0 bits: 56.5 E(85289): 9.6e-08
Smith-Waterman score: 242; 21.6% identity (56.8% similar) in 338 aa overlap (7-325:3-327)
10 20 30 40 50
pF1KE1 MDPQCTMGLSNILFVM-AFLLSGAAPLKIQAYFNETADLPCQFANSQNQSLSELVVFWQD
.: ..::.. . : . . ...:. . ..: : ... .:... :.::
XP_011 MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQT
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 QENLVLNEVYLGKEK-FDSVHSKYMGRTSFDS-----DSWTLRLHNLQIKDKGLYQCIIH
.:. .. .. ... ...: :.: .:. .. ...::: :. .:. ..:..
XP_011 SESKTVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 HKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVLL
.. :. .. ... : : :::: : .: . . ...::.::.:::.:. . .
XP_011 -SQSLGFQEVLSVEVTLHVAANFSVP-VVSAPHSPSQDELTFTCTSINGYPRPN-VYWIN
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 RTKNSTIEYDGIMQKSQD--NVTELYDVSISLSVSFPDVTSNMTIFCILET---DKTRLL
.: :: . : .:.. :. :::: : .. : ...: : .:. ... .
XP_011 KTDNSLL--DQALQNDTVFLNMRGLYDVVSVLRIAR---TPSVNIGCCIENVLLQQNLTV
180 190 200 210 220
230 240 250 260 270 280
pF1KE1 SSPFSIEL-------EDPQPPPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYK
.: . .. :.: .. ..: ...:..: . : . : .
XP_011 GSQTGNDIGERDKITENPVSTGEKNAATWSIL--AVLCLLVVVAVAIGWVCRDRCLQHSY
230 240 250 260 270 280
290 300 310 320
pF1KE1 CGTNTMEREESEQTKKREKIHIPERSDETQRVFKSSKTSSCDKSDTCF
:. .. :.: : .:. .. . .: ..::: .::. .
XP_011 AGAWAVS-PETELTVSRHGFE--QTTDVLPFILKSSLGASCEPTAFPLPPAAPGPCAHLF
290 300 310 320 330 340
XP_011 IWMLAECTPCSPVWSSIS
350 360
>>XP_011511629 (OMIM: 112203) PREDICTED: T-lymphocyte ac (217 aa)
initn: 108 init1: 54 opt: 234 Z-score: 254.8 bits: 54.8 E(85289): 1.9e-07
Smith-Waterman score: 234; 27.7% identity (58.2% similar) in 213 aa overlap (77-278:11-206)
50 60 70 80 90 100
pF1KE1 NQSLSELVVFWQDQENLVLNEVYLGKEKFDSVHSKYMGRTSFD-SDSWTLRLHNLQIKDK
.. .: .:: :: ... .. . :. .:.
XP_011 MVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDE
10 20 30 40
110 120 130 140 150 160
pF1KE1 GLYQCIIHHKKPTGMIRIHQMNSELSVLANFSQPEI----VPISNITENVYINLTCSSIH
: :.:.. . . .. : : . ::: :.: : : .: ::: . . ::.
XP_011 GTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRII-----CSTSG
50 60 70 80 90
170 180 190 200 210 220
pF1KE1 GYPEPKKMSVLLRTKNSTIEYDGIMQK-SQDNVTELYDVSISLSVSFPDVTSNMTIFCIL
:.:::. .: : .:. : ..: ::: :::: :: .:. ..:.: ...:..
XP_011 GFPEPH-LSWL---ENGE-ELNAINTTVSQDPETELYAVSSKLDF---NMTTNHSFMCLI
100 110 120 130 140
230 240 250 260 270
pF1KE1 ETDKTRLLSSPFSIELEDPQPPPDHI-P-WITAVLPT---VIICVMVFCLILWKWKKKKR
. . :. .. :. . . ::.. : : ... . .:: ...:. . ..:
XP_011 KYGHLRV-NQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCF---APRCRER
150 160 170 180 190 200
280 290 300 310 320
pF1KE1 PRNSYKCGTNTMEREESEQTKKREKIHIPERSDETQRVFKSSKTSSCDKSDTCF
::
XP_011 RRNERLRRESVRPV
210
>>NP_001316557 (OMIM: 605715) CD276 antigen isoform b pr (316 aa)
initn: 89 init1: 65 opt: 233 Z-score: 251.4 bits: 54.8 E(85289): 2.9e-07
Smith-Waterman score: 233; 23.9% identity (52.4% similar) in 330 aa overlap (3-313:8-315)
10 20 30 40 50
pF1KE1 MDPQCTMGLSNILFVMAFLLSGAAPLKIQ-----AYFNETADLPCQFANSQNQSL
: . .. : .. : :.:: ... : . : : :.:. . ::
NP_001 MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
10 20 30 40 50 60
60 70 80 90 100
pF1KE1 SELVVFWQ--DQENLVLNEVYLGKEKFDSVHSKYMGRTSFDSD-----SWTLRLHNLQIK
..: ..:: : ..:: . :... : : .::.. : . .:::. ...
NP_001 AQLNLIWQLTDTKQLV-HSFAEGQDQ----GSAYANRTALFPDLLAQGNASLRLQRVRVA
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 DKGLYQCIIHHKKPTGMIRIHQMNSELSVLANFSQPEIV--PISNITENVYINLTCSSIH
:.: . :.. . : . :.: : .:.: .. : ... . ...:::: .
NP_001 DEGSFTCFVS-IRDFGSAAVS-----LQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYR
120 130 140 150 160
170 180 190 200 210 220
pF1KE1 GYPEPKKMSVLLRTKNSTIEYDGIMQKSQ-DNVTELYDVSISLSVSFPDVTSNMTIFCIL
:::: . .. .. . : . :: : :.:: : : . .: : :..
NP_001 GYPEAE----VFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVL---GANGTYSCLV
170 180 190 200 210 220
230 240 250 260 270
pF1KE1 ETDKTRLLSSPFSIELEDPQP---PPDHIPWITAVLPTVIICVMVFCLILWKWKKKKRPR
. . . .. :. . :: ::. . :.:. : . .: ..: : . :.: :.
NP_001 R-NPVLQQDAHGSVTITG-QPMTFPPEAL-WVTVGLSVCLIALLV-ALAFVCWRKIKQSC
230 240 250 260 270
280 290 300 310 320
pF1KE1 NSYKCGTNTMERE-ESEQTKKREKIHIPERSDETQRVFKSSKTSSCDKSDTCF
. . :.. .. : :. .: . : . :. :..
NP_001 EEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA
280 290 300 310
329 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:14:25 2016 done: Sun Nov 6 22:14:26 2016
Total Scan time: 6.580 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]