Result of FASTA (omim) for
pFN21AE1518
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1518, 152 aa
1>>>pF1KE1518 152 - 152 aa - 152 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0453+/-0.000374; mu= 12.3272+/- 0.023
mean_var=57.7050+/-12.133, 0's: 0 Z-trim(112.6): 43 B-trim: 889 in 1/47
Lambda= 0.168837
statistics sampled from 21561 (21600) to 21561 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.253), width: 16
Scan time: 4.970
The best scores are: opt bits E(85289)
NP_058647 (OMIM: 616074) chemokine-like factor iso ( 152) 989 249.0 2.1e-66
NP_001035228 (OMIM: 616074) chemokine-like factor ( 113) 723 184.2 5.3e-47
NP_857592 (OMIM: 616074) chemokine-like factor iso ( 120) 537 138.9 2.4e-33
NP_857591 (OMIM: 616074) chemokine-like factor iso ( 99) 465 121.3 3.9e-28
NP_443725 (OMIM: 607884) CKLF-like MARVEL transmem ( 286) 333 89.4 4.6e-18
NP_851785 (OMIM: 607884) CKLF-like MARVEL transmem ( 231) 299 81.1 1.2e-15
NP_851786 (OMIM: 607884) CKLF-like MARVEL transmem ( 169) 289 78.6 4.9e-15
NP_057410 (OMIM: 616074) chemokine-like factor iso ( 67) 275 74.9 2.4e-14
NP_851787 (OMIM: 607884) CKLF-like MARVEL transmem ( 114) 255 70.2 1.1e-12
NP_612419 (OMIM: 607890) CKLF-like MARVEL transmem ( 175) 161 47.4 1.2e-05
XP_006721194 (OMIM: 607886) PREDICTED: CKLF-like M ( 182) 144 43.2 0.00023
NP_653202 (OMIM: 607886) CKLF-like MARVEL transmem ( 182) 144 43.2 0.00023
NP_853531 (OMIM: 607886) CKLF-like MARVEL transmem ( 182) 144 43.2 0.00023
NP_653274 (OMIM: 607885) CKLF-like MARVEL transmem ( 248) 139 42.1 0.00068
XP_011531621 (OMIM: 607890) PREDICTED: CKLF-like M ( 151) 133 40.5 0.0012
XP_016861135 (OMIM: 607890) PREDICTED: CKLF-like M ( 179) 133 40.6 0.0014
NP_002659 (OMIM: 300112) proteolipid protein 2 [Ho ( 152) 131 40.0 0.0017
XP_016876442 (OMIM: 607888) PREDICTED: CKLF-like M ( 156) 122 37.9 0.0081
XP_016876443 (OMIM: 607888) PREDICTED: CKLF-like M ( 156) 122 37.9 0.0081
NP_612469 (OMIM: 607888) CKLF-like MARVEL transmem ( 156) 122 37.9 0.0081
>>NP_058647 (OMIM: 616074) chemokine-like factor isoform (152 aa)
initn: 989 init1: 989 opt: 989 Z-score: 1313.0 bits: 249.0 E(85289): 2.1e-66
Smith-Waterman score: 989; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KE1 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_058 LLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVC
70 80 90 100 110 120
130 140 150
pF1KE1 CLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
::::::::::::::::::::::::::::::::
NP_058 CLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
130 140 150
>>NP_001035228 (OMIM: 616074) chemokine-like factor isof (113 aa)
initn: 745 init1: 723 opt: 723 Z-score: 964.9 bits: 184.2 E(85289): 5.3e-47
Smith-Waterman score: 723; 99.1% identity (100.0% similar) in 113 aa overlap (1-113:1-113)
10 20 30 40 50 60
pF1KE1 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVC
:::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 LLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGLF
70 80 90 100 110
130 140 150
pF1KE1 CLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
>>NP_857592 (OMIM: 616074) chemokine-like factor isoform (120 aa)
initn: 790 init1: 529 opt: 537 Z-score: 719.6 bits: 138.9 E(85289): 2.4e-33
Smith-Waterman score: 730; 78.9% identity (78.9% similar) in 152 aa overlap (1-152:1-120)
10 20 30 40 50 60
pF1KE1 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_857 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVC
::::::::::::::::::: :::::::::
NP_857 LLYVLRLDRLMKWLFWPLL--------------------------------VFALVTAVC
70 80
130 140 150
pF1KE1 CLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
::::::::::::::::::::::::::::::::
NP_857 CLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
90 100 110 120
>>NP_857591 (OMIM: 616074) chemokine-like factor isoform (99 aa)
initn: 465 init1: 465 opt: 465 Z-score: 626.1 bits: 121.3 E(85289): 3.9e-28
Smith-Waterman score: 530; 65.1% identity (65.1% similar) in 152 aa overlap (1-152:1-99)
10 20 30 40 50 60
pF1KE1 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFI
::::::::::::::::::::::::::
NP_857 MDNVQPKIKHRPFCFSVKGHVKMLRL----------------------------------
10 20
70 80 90 100 110 120
pF1KE1 LLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVC
:::::::::::::::::::::::::::::::::::::::::
NP_857 -------------------DIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVC
30 40 50 60
130 140 150
pF1KE1 CLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
::::::::::::::::::::::::::::::::
NP_857 CLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
70 80 90
>>NP_443725 (OMIM: 607884) CKLF-like MARVEL transmembran (286 aa)
initn: 330 init1: 295 opt: 333 Z-score: 445.3 bits: 89.4 E(85289): 4.6e-18
Smith-Waterman score: 333; 41.6% identity (72.8% similar) in 125 aa overlap (13-135:131-254)
10 20 30 40
pF1KE1 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAP
: :: : .:.:::.: . ... :::.::
NP_443 ESKLLNEMAIKERVEGRAKVPYKFRDSLKRFSFSPTGMLKILRLSLILGALACFIITQAN
110 120 130 140 150 160
50 60 70 80 90 100
pF1KE1 EPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPE
: .:.::..:. ...::::.::: : .:. .: :::::. ::..:.::. .:..::. .
NP_443 ESFITITSLEICIVVFFILIYVLTLHHLLTYLHWPLLDLTNSIITAVFLSVVAILAMQEK
170 180 190 200 210 220
110 120 130 140 150
pF1KE1 TTT--LTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
: :::.. .. :::. :. .. :. :
NP_443 KRRHLLYVGGSLCLTAVIVCCI-DAFVVTTKMRTNLKRFLGVEVERKLSPAKDAYPETGP
230 240 250 260 270
NP_443 DAPQRPA
280
>>NP_851785 (OMIM: 607884) CKLF-like MARVEL transmembran (231 aa)
initn: 323 init1: 288 opt: 299 Z-score: 401.9 bits: 81.1 E(85289): 1.2e-15
Smith-Waterman score: 299; 46.0% identity (76.0% similar) in 100 aa overlap (13-110:131-230)
10 20 30 40
pF1KE1 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAP
: :: : .:.:::.: . ... :::.::
NP_851 ESKLLNEMAIKERVEGRAKVPYKFRDSLKRFSFSPTGMLKILRLSLILGALACFIITQAN
110 120 130 140 150 160
50 60 70 80 90 100
pF1KE1 EPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPE
: .:.::..:. ...::::.::: : .:. .: :::::. ::..:.::. .:..::. .
NP_851 ESFITITSLEICIVVFFILIYVLTLHHLLTYLHWPLLDLTNSIITAVFLSVVAILAMQEK
170 180 190 200 210 220
110 120 130 140 150
pF1KE1 TTT--LTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
: :::
NP_851 KRRHLLYVGGR
230
>>NP_851786 (OMIM: 607884) CKLF-like MARVEL transmembran (169 aa)
initn: 286 init1: 251 opt: 289 Z-score: 390.9 bits: 78.6 E(85289): 4.9e-15
Smith-Waterman score: 289; 40.2% identity (73.2% similar) in 112 aa overlap (26-135:27-137)
10 20 30 40 50
pF1KE1 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFF
:.: . ... :::.:: : .:.::..:. ...::
NP_851 MDPEHAKPESSEAPSGNLKQPETAAALSLILGALACFIITQANESFITITSLEICIVVFF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 ILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTT--LTVGGGVFALVT
::.::: : .:. .: :::::. ::..:.::. .:..::. . : :::.. ..
NP_851 ILIYVLTLHHLLTYLHWPLLDLTNSIITAVFLSVVAILAMQEKKRRHLLYVGGSLCLTAV
70 80 90 100 110 120
120 130 140 150
pF1KE1 AVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
:::. :. .. :. :
NP_851 IVCCI-DAFVVTTKMRTNLKRFLGVEVERKLSPAKDAYPETGPDAPQRPA
130 140 150 160
>>NP_057410 (OMIM: 616074) chemokine-like factor isoform (67 aa)
initn: 275 init1: 275 opt: 275 Z-score: 378.6 bits: 74.9 E(85289): 2.4e-14
Smith-Waterman score: 281; 44.1% identity (44.1% similar) in 152 aa overlap (1-152:1-67)
10 20 30 40 50 60
pF1KE1 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFI
::::::::::::::::::::::::::
NP_057 MDNVQPKIKHRPFCFSVKGHVKMLRL----------------------------------
10 20
70 80 90 100 110 120
pF1KE1 LLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVC
:::::::::
NP_057 ---------------------------------------------------VFALVTAVC
30
130 140 150
pF1KE1 CLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
::::::::::::::::::::::::::::::::
NP_057 CLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
40 50 60
>>NP_851787 (OMIM: 607884) CKLF-like MARVEL transmembran (114 aa)
initn: 260 init1: 240 opt: 255 Z-score: 348.7 bits: 70.2 E(85289): 1.1e-12
Smith-Waterman score: 255; 44.8% identity (77.0% similar) in 87 aa overlap (26-110:27-113)
10 20 30 40 50
pF1KE1 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFF
:.: . ... :::.:: : .:.::..:. ...::
NP_851 MDPEHAKPESSEAPSGNLKQPETAAALSLILGALACFIITQANESFITITSLEICIVVFF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 ILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTT--LTVGGGVFALVT
::.::: : .:. .: :::::. ::..:.::. .:..::. . : :::
NP_851 ILIYVLTLHHLLTYLHWPLLDLTNSIITAVFLSVVAILAMQEKKRRHLLYVGGR
70 80 90 100 110
120 130 140 150
pF1KE1 AVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
>>NP_612419 (OMIM: 607890) CKLF-like MARVEL transmembran (175 aa)
initn: 136 init1: 107 opt: 161 Z-score: 222.1 bits: 47.4 E(85289): 1.2e-05
Smith-Waterman score: 161; 27.0% identity (63.9% similar) in 122 aa overlap (18-130:42-163)
10 20 30 40
pF1KE1 MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAP--EPY
. :. .:..: :: . :: ... :
NP_612 CSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAFICVRSSLWTNY
20 30 40 50 60 70
50 60 70 80 90
pF1KE1 IVITGFEVT------VILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLAL
. . :::. .:: : :....:. :.. . ::: .... :. :...::.:..:
NP_612 SAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGTLLLLIASIVAA
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 IPE-TTTLTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
. . :.:..:..... :.:. : :.
NP_612 SKSYNQSGLVAGAIFGFMATFLCMASIWLSYKISCVTQSTDAAV
140 150 160 170
152 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:27:12 2016 done: Mon Nov 7 02:27:13 2016
Total Scan time: 4.970 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]