Result of FASTA (omim) for
pFN21AE1515
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1515, 260 aa
1>>>pF1KE1515 260 - 260 aa - 260 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2330+/-0.00039; mu= 15.1473+/- 0.024
mean_var=75.3794+/-15.363, 0's: 0 Z-trim(113.5): 115 B-trim: 363 in 3/49
Lambda= 0.147723
statistics sampled from 22766 (22893) to 22766 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.268), width: 16
Scan time: 6.650
The best scores are: opt bits E(85289)
NP_001229454 (OMIM: 142880) HLA class II histocomp ( 260) 1714 374.6 9.7e-104
NP_291032 (OMIM: 142880) HLA class II histocompati ( 260) 1714 374.6 9.7e-104
NP_001229453 (OMIM: 142880) HLA class II histocomp ( 260) 1714 374.6 9.7e-104
NP_061984 (OMIM: 142860) HLA class II histocompati ( 254) 1022 227.1 2.4e-59
NP_002113 (OMIM: 146880,212750) HLA class II histo ( 255) 979 218.0 1.4e-56
NP_064440 (OMIM: 613503) HLA class II histocompati ( 255) 958 213.5 3e-55
NP_002110 (OMIM: 142930) HLA class II histocompati ( 250) 938 209.2 5.7e-54
XP_006715142 (OMIM: 146880,212750) PREDICTED: HLA ( 206) 790 177.6 1.5e-44
NP_006111 (OMIM: 142855) HLA class II histocompati ( 261) 361 86.3 6.2e-17
NP_002112 (OMIM: 142858) HLA class II histocompati ( 258) 289 70.9 2.5e-12
NP_001287719 (OMIM: 615161) HLA class II histocomp ( 264) 268 66.5 5.7e-11
XP_005249108 (OMIM: 615161) PREDICTED: HLA class I ( 275) 268 66.5 5.9e-11
NP_001230890 (OMIM: 123400,126200,212750,604305) H ( 269) 258 64.3 2.6e-10
NP_001230894 (OMIM: 126200,142857,180300,181000) m ( 266) 255 63.7 3.9e-10
XP_011512862 (OMIM: 615161) PREDICTED: HLA class I ( 256) 253 63.3 5.1e-10
NP_002116 (OMIM: 604776) major histocompatibility ( 266) 250 62.6 8.3e-10
XP_011546040 (OMIM: 126200,142857,180300,181000) P ( 266) 250 62.6 8.3e-10
XP_011512864 (OMIM: 604776) PREDICTED: major histo ( 276) 250 62.6 8.5e-10
NP_002109 (OMIM: 142856) HLA class II histocompati ( 263) 248 62.2 1.1e-09
NP_002115 (OMIM: 126200,142857,180300,181000) majo ( 266) 247 62.0 1.3e-09
NP_002114 (OMIM: 123400,126200,212750,604305) HLA ( 261) 241 60.7 3.1e-09
NP_001230891 (OMIM: 123400,126200,212750,604305) H ( 261) 241 60.7 3.1e-09
NP_072049 (OMIM: 612735) major histocompatibility ( 266) 238 60.1 4.9e-09
NP_004039 (OMIM: 105200,109700,241600) beta-2-micr ( 119) 228 57.7 1.1e-08
XP_005254606 (OMIM: 105200,109700,241600) PREDICTE ( 122) 226 57.3 1.6e-08
NP_001185787 (OMIM: 615161) HLA class II histocomp ( 227) 229 58.1 1.6e-08
NP_002111 (OMIM: 600629) HLA class II histocompati ( 273) 229 58.2 1.9e-08
XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 226 57.5 2.5e-08
XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 226 57.6 3.3e-08
NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 226 57.6 3.5e-08
XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 226 57.6 3.8e-08
XP_016866301 (OMIM: 143110) PREDICTED: HLA class I ( 420) 226 57.7 4.1e-08
XP_016866299 (OMIM: 143110) PREDICTED: HLA class I ( 435) 226 57.7 4.2e-08
NP_001091949 (OMIM: 143110) HLA class I histocompa ( 442) 226 57.7 4.2e-08
XP_011512863 (OMIM: 615161) PREDICTED: HLA class I ( 219) 222 56.6 4.4e-08
XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 217 55.7 1.3e-07
XP_016866300 (OMIM: 143110) PREDICTED: HLA class I ( 431) 217 55.8 1.6e-07
XP_016866307 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 212 54.5 2.1e-07
XP_016866306 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 212 54.5 2.1e-07
XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 206 53.2 5.3e-07
NP_001181928 (OMIM: 600764) major histocompatibili ( 296) 206 53.3 6e-07
NP_001522 (OMIM: 600764) major histocompatibility ( 341) 206 53.3 6.6e-07
NP_620573 (OMIM: 104300,176100,176200,235200,61263 ( 256) 204 52.8 7.2e-07
NP_001129491 (OMIM: 601437) IgG receptor FcRn larg ( 365) 199 51.9 2e-06
NP_004098 (OMIM: 601437) IgG receptor FcRn large s ( 365) 199 51.9 2e-06
NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 198 51.7 2.3e-06
NP_620577 (OMIM: 104300,176100,176200,235200,61263 ( 246) 194 50.7 3e-06
NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 196 51.2 3.1e-06
NP_620575 (OMIM: 104300,176100,176200,235200,61263 ( 334) 194 50.8 3.9e-06
NP_620579 (OMIM: 104300,176100,176200,235200,61263 ( 168) 190 49.7 4.1e-06
>>NP_001229454 (OMIM: 142880) HLA class II histocompatib (260 aa)
initn: 1755 init1: 1714 opt: 1714 Z-score: 1983.5 bits: 374.6 E(85289): 9.7e-104
Smith-Waterman score: 1714; 97.3% identity (98.8% similar) in 260 aa overlap (1-260:1-260)
10 20 30 40 50 60
pF1KE1 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPEV
:.::::::::::::::::::.::::::::::::::::::::::::::::::::.::::::
NP_001 EMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKFH
:::::::::::::::::::::.::::::::::::::: ::::::::::::::::::::::
NP_001 TVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 YLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG
190 200 210 220 230 240
250 260
pF1KE1 TVLIIKSLRSGHDPRAQGPL
:::::::::::::::::: :
NP_001 TVLIIKSLRSGHDPRAQGTL
250 260
>>NP_291032 (OMIM: 142880) HLA class II histocompatibili (260 aa)
initn: 1755 init1: 1714 opt: 1714 Z-score: 1983.5 bits: 374.6 E(85289): 9.7e-104
Smith-Waterman score: 1714; 97.3% identity (98.8% similar) in 260 aa overlap (1-260:1-260)
10 20 30 40 50 60
pF1KE1 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_291 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPEV
:.::::::::::::::::::.::::::::::::::::::::::::::::::::.::::::
NP_291 EMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKFH
:::::::::::::::::::::.::::::::::::::: ::::::::::::::::::::::
NP_291 TVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 YLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_291 YLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG
190 200 210 220 230 240
250 260
pF1KE1 TVLIIKSLRSGHDPRAQGPL
:::::::::::::::::: :
NP_291 TVLIIKSLRSGHDPRAQGTL
250 260
>>NP_001229453 (OMIM: 142880) HLA class II histocompatib (260 aa)
initn: 1755 init1: 1714 opt: 1714 Z-score: 1983.5 bits: 374.6 E(85289): 9.7e-104
Smith-Waterman score: 1714; 97.3% identity (98.8% similar) in 260 aa overlap (1-260:1-260)
10 20 30 40 50 60
pF1KE1 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPEV
:.::::::::::::::::::.::::::::::::::::::::::::::::::::.::::::
NP_001 EMFYVDLDKKETVWHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKFH
:::::::::::::::::::::.::::::::::::::: ::::::::::::::::::::::
NP_001 TVFPKEPVELGQPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 YLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLTFVPSAEDFYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG
190 200 210 220 230 240
250 260
pF1KE1 TVLIIKSLRSGHDPRAQGPL
:::::::::::::::::: :
NP_001 TVLIIKSLRSGHDPRAQGTL
250 260
>>NP_061984 (OMIM: 142860) HLA class II histocompatibili (254 aa)
initn: 1008 init1: 1008 opt: 1022 Z-score: 1186.6 bits: 227.1 E(85289): 2.4e-59
Smith-Waterman score: 1022; 60.7% identity (81.4% similar) in 247 aa overlap (14-260:8-254)
10 20 30 40 50 60
pF1KE1 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDED
.: . .: :.: . . ::: .:: : : . .:::::.:: :
NP_061 MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGD
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPEV
: :.::. ::::::.:::::: ::::::.:::::. . ::. . .:::.: .: ::::
NP_061 EIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 TVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKFH
::. . :::: .::.::: ::.: :::.::::: ::.::: ::.:..:::: :. :.:::
NP_061 TVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 YLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVG
:: :.::.::::::::::::::.::::::: . : .:::::.:.:::::..::::::.:
NP_061 YLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIG
180 190 200 210 220 230
250 260
pF1KE1 TVLIIKSLRSGHDPRAQGPL
:..:::.::... . .:::
NP_061 TIFIIKGLRKSNAAERRGPL
240 250
>>NP_002113 (OMIM: 146880,212750) HLA class II histocomp (255 aa)
initn: 966 init1: 929 opt: 979 Z-score: 1137.0 bits: 218.0 E(85289): 1.4e-56
Smith-Waterman score: 979; 56.5% identity (79.6% similar) in 255 aa overlap (7-260:1-255)
10 20 30 40 50
pF1KE1 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDE
:. .:..: ::.:. ..: :. : ::::.. .. . : . :.:.. :::
NP_002 MILNKALLLGALALTTVMSPCGGEDIVADHVASCGVNLYQFYGPSGQYTHEFDG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 DEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPE
::::::::..:::.:. ::.. .:. ::.: :.:. ..::: .:.: : : :.:. ::
NP_002 DEQFYVDLERKETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRYNSTAATNEVPE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKF
:::: : :: ::::::::: .: .::::.:.::: ::. :::::.:. :: ..:.:: :.
NP_002 VTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 HYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIV
::::.:::...:::.::::::::::::::: . : : : ::::.::::: .::.::.:
NP_002 SYLTFLPSADEIYDCKVEHWGLDQPLLKHWEPEIPAPMSELTETVVCALGLSVGLMGIVV
180 190 200 210 220 230
240 250 260
pF1KE1 GTVLIIKSLRSGHDPRAQGPL
:::.::..::: : ::::
NP_002 GTVFIIQGLRSVGASRHQGPL
240 250
>>NP_064440 (OMIM: 613503) HLA class II histocompatibili (255 aa)
initn: 921 init1: 851 opt: 958 Z-score: 1112.8 bits: 213.5 E(85289): 3e-55
Smith-Waterman score: 958; 55.3% identity (80.4% similar) in 255 aa overlap (7-260:1-255)
10 20 30 40 50
pF1KE1 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDE
:. .:..: ::.:. ..: :. : ::::..:.. : :.: :.:.. :::
NP_064 MILNKALLLGALALTAVMSPCGGEDIVADHVASYGVNFYQSHGPSGQYTHEFDG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 DEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPE
::.:::::. :::::.: :.. .::. :..: :.:. ...:. ....:: : :.:. ::
NP_064 DEEFYVDLETKETVWQLPMFSKFISFDPQSALRNMAVGKHTLEFMMRQSNSTAATNEVPE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKF
:::: : :: ::::::::: .: .::::.:.::: ::. :::::.:. :: ..:.:: :.
NP_064 VTVFSKFPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 HYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIV
::::.:::...:::.:::::::.::::::: . : : : :::..::::: .::.::.:
NP_064 SYLTFLPSADEIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETLVCALGLSVGLMGIVV
180 190 200 210 220 230
240 250 260
pF1KE1 GTVLIIKSLRSGHDPRAQGPL
:::.::..::: : :: :
NP_064 GTVFIIQGLRSVGASRHQGLL
240 250
>>NP_002110 (OMIM: 142930) HLA class II histocompatibili (250 aa)
initn: 933 init1: 877 opt: 938 Z-score: 1089.9 bits: 209.2 E(85289): 5.7e-54
Smith-Waterman score: 938; 56.9% identity (78.2% similar) in 248 aa overlap (10-255:3-250)
10 20 30 40 50
pF1KE1 MRPEDRMFHIRA-VILRALSLAFLLSLRGAGAIKADHVSTYA-AFVQTHRPTGEFMFEFD
.:: ..: .: ::: . ::: ::::...:. :: :.. .:.: :::
NP_002 MALRAGLVLGFHTLMTLLSPQEAGATKADHMGSYGPAFYQSYGASGQFTHEFD
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 EDEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPP
:.. : ::: :.:.::.: ::: :. :::::.:: .. .:. :..:::...: : ::
NP_002 EEQLFSVDLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILVERSNRSRAINVPP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 EVTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHK
.:::.:: ::::::: ::: .: .::::.:.::: ::. ::::::.. : . :. :.:
NP_002 RVTVLPKSRVELGQPNILICIVDNIFPPVINITWLRNGQTVTEGVAQTSFYSQPDHLFRK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 FHYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGII
:::: :::::::::::.::::::: :::.::: : :: :.. ::..:::::..::::..
NP_002 FHYLPFVPSAEDVYDCQVEHWGLDAPLLRHWELQVPIPPPDAMETLVCALGLAIGLVGFL
180 190 200 210 220 230
240 250 260
pF1KE1 VGTVLIIKSLRSGHDPRAQGPL
::::::: . . ::
NP_002 VGTVLIIMGTYVSSVPR
240 250
>>XP_006715142 (OMIM: 146880,212750) PREDICTED: HLA clas (206 aa)
initn: 777 init1: 740 opt: 790 Z-score: 920.6 bits: 177.6 E(85289): 1.5e-44
Smith-Waterman score: 790; 55.4% identity (80.4% similar) in 204 aa overlap (7-209:1-204)
10 20 30 40 50
pF1KE1 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAA-FVQTHRPTGEFMFEFDE
:. .:..: ::.:. ..: :. : ::::.. .. . : . :.:.. :::
XP_006 MILNKALLLGALALTTVMSPCGGEDIVADHVASCGVNLYQFYGPSGQYTHEFDG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 DEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPE
::::::::..:::.:. ::.. .:. ::.: :.:. ..::: .:.: : : :.:. ::
XP_006 DEQFYVDLERKETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRYNSTAATNEVPE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKF
:::: : :: ::::::::: .: .::::.:.::: ::. :::::.:. :: ..:.:: :.
XP_006 VTVFSKSPVTLGQPNTLICLVDNIFPPVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 HYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIV
::::.:::...:::.::::::::::::::
XP_006 SYLTFLPSADEIYDCKVEHWGLDQPLLKHWVE
180 190 200
>>NP_006111 (OMIM: 142855) HLA class II histocompatibili (261 aa)
initn: 353 init1: 147 opt: 361 Z-score: 425.1 bits: 86.3 E(85289): 6.2e-17
Smith-Waterman score: 361; 31.0% identity (59.7% similar) in 216 aa overlap (35-245:41-252)
10 20 30 40 50 60
pF1KE1 DRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDEDEQFY
.:. .... : :. . .:::. :.
NP_006 LLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFF
20 30 40 50 60 70
70 80 90 100 110
pF1KE1 VDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDP-----PE
:.... : .: :: : . :: : . .. . .::. . .. : :
NP_006 FDFSQNTRVPRLPEF--ADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPI
80 90 100 110 120
120 130 140 150 160 170
pF1KE1 VTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKF
. :: .:.:.:.::::.: .. .:::.:.:.: .. :: :: . .. ::. :
NP_006 AEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPV-EGFGPTFVSAVDGLSFQAF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 HYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIV
::.:.: :...: : : . .: .. . . :.:::.... ::..::::
NP_006 SYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALP-SDLLENVLCGVAFGLGVLGIIV
190 200 210 220 230 240
240 250 260
pF1KE1 GTVLIIKSLRSGHDPRAQGPL
: ::::
NP_006 GIVLIIYFRKPCSGD
250 260
>>NP_002112 (OMIM: 142858) HLA class II histocompatibili (258 aa)
initn: 250 init1: 228 opt: 289 Z-score: 342.2 bits: 70.9 E(85289): 2.5e-12
Smith-Waterman score: 289; 28.0% identity (55.6% similar) in 243 aa overlap (11-243:11-246)
10 20 30 40 50
pF1KE1 MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHV----STYAAFVQTHRPTGEFMFE
:.: : :: ...: :. . : ... . :: :.: .....
NP_002 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRFLERYIYN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 FDEDEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLNTLIQRSNH------
.: .: :. . ..: :.:: . : .. .: . . . : :.
NP_002 REEFARFDSDVGEFRAV---TELGRP-AAEYWNSQKDILEEKRAVPDRMCRHNYELGGPM
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 TQAANDPPEVTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLP
: :.:.: :.. : . : :.::. :.: ..: :. ::. : ::. . ..
NP_002 TLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 RTDYSFHKFHYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGL
:..:. . .: ..:. ::: :.::: .::.:. .:.:: ..:. : :.
NP_002 NGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSD---SARSKTLTGAGGF
180 190 200 210 220 230
240 250 260
pF1KE1 VLGLVGIIVGTVLIIKSLRSGHDPRAQGPL
::::. :: .
NP_002 VLGLIICGVGIFMHRRSKKVQRGSA
240 250
260 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:59:43 2016 done: Mon Nov 7 01:59:44 2016
Total Scan time: 6.650 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]