Result of FASTA (omim) for
pFN21AE1511
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1511, 322 aa
1>>>pF1KE1511 322 - 322 aa - 322 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2902+/-0.000351; mu= 15.8629+/- 0.022
mean_var=62.9827+/-12.603, 0's: 0 Z-trim(113.9): 11 B-trim: 0 in 0/50
Lambda= 0.161608
statistics sampled from 23465 (23474) to 23465 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.275), width: 16
Scan time: 7.750
The best scores are: opt bits E(85289)
NP_000036 (OMIM: 207800,608313) arginase-1 isoform ( 322) 2133 505.8 4.7e-143
NP_001231367 (OMIM: 207800,608313) arginase-1 isof ( 330) 2107 499.8 3.2e-141
NP_001163 (OMIM: 107830) arginase-2, mitochondrial ( 354) 1336 320.0 4.4e-87
XP_011534103 (OMIM: 207800,608313) PREDICTED: argi ( 237) 884 214.6 1.7e-55
>>NP_000036 (OMIM: 207800,608313) arginase-1 isoform 2 [ (322 aa)
initn: 2133 init1: 2133 opt: 2133 Z-score: 2689.3 bits: 505.8 E(85289): 4.7e-143
Smith-Waterman score: 2133; 100.0% identity (100.0% similar) in 322 aa overlap (1-322:1-322)
10 20 30 40 50 60
pF1KE1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
250 260 270 280 290 300
310 320
pF1KE1 LACFGLAREGNHKPIDYLNPPK
::::::::::::::::::::::
NP_000 LACFGLAREGNHKPIDYLNPPK
310 320
>>NP_001231367 (OMIM: 207800,608313) arginase-1 isoform (330 aa)
initn: 2119 init1: 1858 opt: 2107 Z-score: 2656.4 bits: 499.8 E(85289): 3.2e-141
Smith-Waterman score: 2107; 97.6% identity (97.6% similar) in 330 aa overlap (1-322:1-330)
10 20 30 40 50
pF1KE1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQ--------ECDVKDYGD
::::::::::::::::::::::::::::::::::::::::::: :::::::::
NP_001 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQVTQNFLILECDVKDYGD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 LPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 RVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 DIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 VDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRT
250 260 270 280 290 300
300 310 320
pF1KE1 VNTAVAITLACFGLAREGNHKPIDYLNPPK
::::::::::::::::::::::::::::::
NP_001 VNTAVAITLACFGLAREGNHKPIDYLNPPK
310 320 330
>>NP_001163 (OMIM: 107830) arginase-2, mitochondrial pre (354 aa)
initn: 1353 init1: 1110 opt: 1336 Z-score: 1684.4 bits: 320.0 E(85289): 4.4e-87
Smith-Waterman score: 1336; 60.1% identity (85.4% similar) in 316 aa overlap (7-321:25-340)
10 20 30 40
pF1KE1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKE
....::::::.:: : :::.::...:.:::...:.
NP_001 MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 QECDVKDYGDLPFADIPNDSPFQ-IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDH
: .::.::: :. .:.:. .. .. :::::: :...:: :... ..: ..:::::
NP_001 LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 SLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPG
:::::.:::::: ::: :.:::::.::::::::.:::::::::::::.::. :.:..::
NP_001 SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 FSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLG
:::. ::::. .::::::::::: ::.:::. :.:::: ..::::: ::::.:.. :.:
NP_001 FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE1 RKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPS
...::::::::.:..::...::::::::::::::::.::.:::..:::::.::..::::.
NP_001 KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
250 260 270 280 290 300
290 300 310 320
pF1KE1 LGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK
:. . ::. :.: :: . . :: .:::.: : : :
NP_001 LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
310 320 330 340 350
>>XP_011534103 (OMIM: 207800,608313) PREDICTED: arginase (237 aa)
initn: 876 init1: 876 opt: 884 Z-score: 1117.5 bits: 214.6 E(85289): 1.7e-55
Smith-Waterman score: 1367; 73.6% identity (73.6% similar) in 322 aa overlap (1-322:1-237)
10 20 30 40 50 60
pF1KE1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
::::::::::::::::::::::::::::::::::::::::::
XP_011 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHS------------------
70 80 90 100
130 140 150 160 170 180
pF1KE1 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
XP_011 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE1 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------YILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
110 120 130 140 150
250 260 270 280 290 300
pF1KE1 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
160 170 180 190 200 210
310 320
pF1KE1 LACFGLAREGNHKPIDYLNPPK
::::::::::::::::::::::
XP_011 LACFGLAREGNHKPIDYLNPPK
220 230
322 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:44:31 2016 done: Mon Nov 7 00:44:32 2016
Total Scan time: 7.750 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]