Result of FASTA (omim) for
pFN21AE1507
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1507, 295 aa
1>>>pF1KE1507 295 - 295 aa - 295 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3646+/-0.000405; mu= 15.0635+/- 0.025
mean_var=66.1368+/-13.658, 0's: 0 Z-trim(110.4): 37 B-trim: 838 in 1/52
Lambda= 0.157708
statistics sampled from 18736 (18770) to 18736 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.22), width: 16
Scan time: 6.730
The best scores are: opt bits E(85289)
NP_954854 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 1931 448.4 7.7e-126
NP_004051 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 1931 448.4 7.7e-126
NP_004345 (OMIM: 603203) cyclin-G2 [Homo sapiens] ( 344) 972 230.2 4.2e-60
XP_011530700 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 972 230.2 4.2e-60
XP_011530701 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 972 230.2 4.2e-60
NP_444284 (OMIM: 168461,193300,254500) G1/S-specif ( 295) 217 58.4 1.9e-08
NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] ( 432) 211 57.1 6.8e-08
NP_001750 (OMIM: 123833,615938) G1/S-specific cycl ( 289) 190 52.3 1.3e-06
NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 i ( 292) 182 50.5 4.7e-06
NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 177 49.4 1.4e-05
XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 177 49.4 1.4e-05
XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 177 49.4 1.4e-05
XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 177 49.4 1.4e-05
NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 177 49.4 1.4e-05
NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D ( 242) 174 48.6 1.4e-05
NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [H ( 464) 177 49.4 1.5e-05
NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo ( 465) 177 49.4 1.5e-05
NP_391990 (OMIM: 300456) G2/mitotic-specific cycli ( 291) 165 46.6 6.9e-05
XP_011515668 (OMIM: 603775) PREDICTED: G1/S-specif ( 288) 160 45.5 0.00015
XP_016869448 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 160 45.5 0.0002
XP_016869446 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 160 45.5 0.0002
NP_477097 (OMIM: 603775) G1/S-specific cyclin-E2 [ ( 404) 160 45.5 0.0002
XP_016869447 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 160 45.5 0.0002
NP_004692 (OMIM: 602755) G2/mitotic-specific cycli ( 398) 159 45.3 0.00023
NP_066970 (OMIM: 607752,615872) cyclin-O [Homo sap ( 350) 156 44.6 0.00033
NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D ( 211) 150 43.1 0.00056
XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specif ( 276) 148 42.7 0.00096
>>NP_954854 (OMIM: 601578) cyclin-G1 [Homo sapiens] (295 aa)
initn: 1931 init1: 1931 opt: 1931 Z-score: 2380.2 bits: 448.4 E(85289): 7.7e-126
Smith-Waterman score: 1931; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295)
10 20 30 40 50 60
pF1KE1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 LIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
250 260 270 280 290
>>NP_004051 (OMIM: 601578) cyclin-G1 [Homo sapiens] (295 aa)
initn: 1931 init1: 1931 opt: 1931 Z-score: 2380.2 bits: 448.4 E(85289): 7.7e-126
Smith-Waterman score: 1931; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295)
10 20 30 40 50 60
pF1KE1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTF
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
250 260 270 280 290
>>NP_004345 (OMIM: 603203) cyclin-G2 [Homo sapiens] (344 aa)
initn: 972 init1: 498 opt: 972 Z-score: 1200.0 bits: 230.2 E(85289): 4.2e-60
Smith-Waterman score: 972; 52.8% identity (79.3% similar) in 290 aa overlap (3-292:7-295)
10 20 30 40 50
pF1KE1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEV
: :. .. .:: ::. :::: : ::. :: :::.. .: . ::. .:
NP_004 MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 KDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVP
.:: ::..::: :::: ::::.:::::. :::.::::.:.:. : ::.. .::. :.:
NP_004 EDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 LATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNS
. :.::::: . :.::. :::::. ::. ....::::..::.::.... . ::..
NP_004 STHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTS-ERKEI
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 INFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGR
.....::::::::.::.:::::::::::: .. ::... : ::: : . ..::::::
NP_004 LSLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 DLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
.. .:.:::::::.:::: .: ::...:: :::: :::..:..::: . .::::::
NP_004 EFFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCF
240 250 260 270 280 290
NP_004 DESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS
300 310 320 330 340
>>XP_011530700 (OMIM: 603203) PREDICTED: cyclin-G2 isofo (344 aa)
initn: 972 init1: 498 opt: 972 Z-score: 1200.0 bits: 230.2 E(85289): 4.2e-60
Smith-Waterman score: 972; 52.8% identity (79.3% similar) in 290 aa overlap (3-292:7-295)
10 20 30 40 50
pF1KE1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEV
: :. .. .:: ::. :::: : ::. :: :::.. .: . ::. .:
XP_011 MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 KDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVP
.:: ::..::: :::: ::::.:::::. :::.::::.:.:. : ::.. .::. :.:
XP_011 EDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 LATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNS
. :.::::: . :.::. :::::. ::. ....::::..::.::.... . ::..
XP_011 STHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTS-ERKEI
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 INFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGR
.....::::::::.::.:::::::::::: .. ::... : ::: : . ..::::::
XP_011 LSLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 DLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
.. .:.:::::::.:::: .: ::...:: :::: :::..:..::: . .::::::
XP_011 EFFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCF
240 250 260 270 280 290
XP_011 DESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS
300 310 320 330 340
>>XP_011530701 (OMIM: 603203) PREDICTED: cyclin-G2 isofo (344 aa)
initn: 972 init1: 498 opt: 972 Z-score: 1200.0 bits: 230.2 E(85289): 4.2e-60
Smith-Waterman score: 972; 52.8% identity (79.3% similar) in 290 aa overlap (3-292:7-295)
10 20 30 40 50
pF1KE1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEV
: :. .. .:: ::. :::: : ::. :: :::.. .: . ::. .:
XP_011 MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 KDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVP
.:: ::..::: :::: ::::.:::::. :::.::::.:.:. : ::.. .::. :.:
XP_011 EDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 LATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNS
. :.::::: . :.::. :::::. ::. ....::::..::.::.... . ::..
XP_011 STHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTS-ERKEI
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 INFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGR
.....::::::::.::.:::::::::::: .. ::... : ::: : . ..::::::
XP_011 LSLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 DLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
.. .:.:::::::.:::: .: ::...:: :::: :::..:..::: . .::::::
XP_011 EFFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCF
240 250 260 270 280 290
XP_011 DESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS
300 310 320 330 340
>>NP_444284 (OMIM: 168461,193300,254500) G1/S-specific c (295 aa)
initn: 111 init1: 69 opt: 217 Z-score: 272.6 bits: 58.4 E(85289): 1.9e-08
Smith-Waterman score: 217; 24.9% identity (57.2% similar) in 201 aa overlap (17-213:28-213)
10 20 30 40
pF1KE1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTA
: :.:. : : :.: .. ... ..
NP_444 MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQK------EVLP
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 RLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSI
.: . . .: . . . :.: ::.: :::::: :. ..: .: .:...: :
NP_444 SMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 EEERNVPLATDLIRI-SQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLL---
: ..::... . : .. . .:..:: ....:. :.. : : .:.. . : .
NP_444 E---TIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 QENLPLERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIE
.:: . :... .: : : . : . ::..: . .. .:
NP_444 EENKQIIRKHAQTFVAL------CATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLS
180 190 200 210 220
230 240 250 260 270 280
pF1KE1 CLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRIT
NP_444 YYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLAC
230 240 250 260 270 280
>>NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] (432 aa)
initn: 183 init1: 104 opt: 211 Z-score: 262.7 bits: 57.1 E(85289): 6.8e-08
Smith-Waterman score: 213; 31.7% identity (61.5% similar) in 161 aa overlap (2-162:170-319)
10 20 30
pF1KE1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKV
. : . : .. .: : :.: .:.:::
NP_001 PLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHEDIHTY--LREMEVKCKPKV
140 150 160 170 180 190
40 50 60 70 80 90
pF1KE1 CGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQP
: ... : .: .: . : :. . . . ...::. :::: .:::::.:.:
NP_001 -GY--MKKQPD----ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLR
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE1 KHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKA
.: :: . . :: : :: : ..... :.. .: ....:::..::. . . . :
NP_001 GKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAA
260 270 280 290 300
160 170 180 190 200 210
pF1KE1 TTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALE
:. ::: :.
NP_001 PTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVT
310 320 330 340 350 360
>>NP_001750 (OMIM: 123833,615938) G1/S-specific cyclin-D (289 aa)
initn: 113 init1: 94 opt: 190 Z-score: 239.5 bits: 52.3 E(85289): 1.3e-06
Smith-Waterman score: 190; 25.4% identity (57.3% similar) in 213 aa overlap (17-226:27-225)
10 20 30 40 50
pF1KE1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTAR
:. :: : : :. .. .. .: .
NP_001 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQ--KD----IQPY
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 LRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIE
.: . . .: . . . :.: ::.: :::::. . . .:: .: :..:: : :
NP_001 MRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKE
60 70 80 90 100 110
120 130 140 150 160
pF1KE1 EERNVPLATDLIRI-SQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENL
. ::... . : .. . ..:.. : .:: :. :.. :.: .:.. .:.. :
NP_001 ---TSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIE---HILRK-L
120 130 140 150 160
170 180 190 200 210 220
pF1KE1 PLERRNSINFERLEAQ--LKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECL
: ..:..... : .:: . : . :. ::..: . .. : . . : . .. :
NP_001 P-QQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCD
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 QKHSKINGRDLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHL
NP_001 ALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRD
230 240 250 260 270 280
>>NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 isofo (292 aa)
initn: 98 init1: 80 opt: 182 Z-score: 229.6 bits: 50.5 E(85289): 4.7e-06
Smith-Waterman score: 182; 24.3% identity (53.0% similar) in 251 aa overlap (17-260:28-265)
10 20 30 40
pF1KE1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTA
:..::. : : :.. .. .. ..
NP_001 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQR------EIKP
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 RLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSI
..: . . .: . . . :.: ::.: :::.:: . .. .: .: :. :: :
NP_001 HMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLR
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 EEERNVPLATDLIRI-SQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQEN
: ..::. . . : ... . .: : .:: :. : . :. : .:: . : . .
NP_001 E---TTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLA--FILHRLS
120 130 140 150 160
170 180 190 200 210 220
pF1KE1 LPLERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQ
:: .:. .. .. .. : : :. ::..: . :. .:. .. : : .
NP_001 LPRDRQALVK-KHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMS-GDELTE
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 KHSKINGRDLTFW---QELVSKCLTEY---SSNKCSKPNVQKLKWIVSGRTARQLKHSYY
. :.: .. :: . : : .:. :.:
NP_001 LLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDV
230 240 250 260 270 280
290
pF1KE1 RITHLPTIPEMVP
NP_001 TAIHL
290
>>NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [Homo (421 aa)
initn: 191 init1: 103 opt: 177 Z-score: 221.1 bits: 49.4 E(85289): 1.4e-05
Smith-Waterman score: 184; 27.9% identity (58.2% similar) in 208 aa overlap (3-210:160-350)
10 20 30
pF1KE1 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVC
.:...:. . ..: : : : : .::.
NP_001 HFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQY--LREAEIRHRPKA-
130 140 150 160 170 180
40 50 60 70 80 90
pF1KE1 GLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPK
. ... : .: .: . : :. . . . . .::. ::::.:::::: :.:
NP_001 --HYMKKQPD----ITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG
190 200 210 220 230 240
100 110 120 130 140 150
pF1KE1 HLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKAT
.: :: . . :: : :: : . ... :.. .: .:..::...:. . . . .
NP_001 KLQLVGTAAMLLASK--YEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVP
250 260 270 280 290
160 170 180 190 200 210
pF1KE1 TAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEI
:. ::: : : .... .. .: .. . :.: : : ::..: . . :
NP_001 TTNQFLLQY--LRRQGVCVRTENLAKYVAELSLLEADP----FLKYLPSLIAAAAFCLAN
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE1 QAQKCVELTEGIECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGR
NP_001 YTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLM
360 370 380 390 400 410
295 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:38:17 2016 done: Sun Nov 6 23:38:18 2016
Total Scan time: 6.730 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]