Result of FASTA (ccds) for
pFN21AE1501
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1501, 283 aa
1>>>pF1KE1501 283 - 283 aa - 283 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6124+/-0.00075; mu= 16.0511+/- 0.045
mean_var=132.3174+/-24.763, 0's: 0 Z-trim(114.4): 61 B-trim: 22 in 1/50
Lambda= 0.111498
statistics sampled from 14948 (15010) to 14948 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.461), width: 16
Scan time: 2.660
The best scores are: opt bits E(32554)
CCDS44046.1 TNFRSF14 gene_id:8764|Hs108|chr1 ( 283) 2050 340.3 9.3e-94
CCDS13393.1 CD40 gene_id:958|Hs108|chr20 ( 277) 381 71.8 6.1e-13
CCDS13394.1 CD40 gene_id:958|Hs108|chr20 ( 203) 368 69.6 2.1e-12
CCDS145.1 TNFRSF1B gene_id:7133|Hs108|chr1 ( 461) 366 69.7 4.4e-12
CCDS13532.1 TNFRSF6B gene_id:8771|Hs108|chr20 ( 300) 352 67.2 1.6e-11
CCDS59233.1 LTBR gene_id:4055|Hs108|chr12 ( 416) 353 67.6 1.8e-11
CCDS8544.1 LTBR gene_id:4055|Hs108|chr12 ( 435) 350 67.1 2.5e-11
>>CCDS44046.1 TNFRSF14 gene_id:8764|Hs108|chr1 (283 aa)
initn: 2050 init1: 2050 opt: 2050 Z-score: 1796.7 bits: 340.3 E(32554): 9.3e-94
Smith-Waterman score: 2050; 99.6% identity (100.0% similar) in 283 aa overlap (1-283:1-283)
10 20 30 40 50 60
pF1KE1 MEPPGDWGPPPWRSTPRTDVLRLVLYLTFLGAPCYAPALPSCKEDEYPVGSECCPKCSPG
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS44 MEPPGDWGPPPWRSTPKTDVLRLVLYLTFLGAPCYAPALPSCKEDEYPVGSECCPKCSPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 CSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 CSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 HQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIICVKRRKPRGDVVKVIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIICVKRRKPRGDVVKVIVS
190 200 210 220 230 240
250 260 270 280
pF1KE1 VQRKRQEAEGEATVIEALQAPPDVTTVAVEETIPSFTGRSPNH
:::::::::::::::::::::::::::::::::::::::::::
CCDS44 VQRKRQEAEGEATVIEALQAPPDVTTVAVEETIPSFTGRSPNH
250 260 270 280
>>CCDS13393.1 CD40 gene_id:958|Hs108|chr20 (277 aa)
initn: 269 init1: 269 opt: 381 Z-score: 345.9 bits: 71.8 E(32554): 6.1e-13
Smith-Waterman score: 381; 31.9% identity (61.0% similar) in 182 aa overlap (21-197:6-182)
10 20 30 40 50
pF1KE1 MEPPGDWGPPPWRSTPRTDVLRLVLYLTFLGAPCYAPALPS-CKEDEYPVGSECCPKCSP
:. ::. .: : : :. :.: .: ..:.:: :.:
CCDS13 MVRLPLQCVLWGCLLTA--VHPEPPTACREKQYLINSQCCSLCQP
10 20 30 40
60 70 80 90 100 110
pF1KE1 GYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVC
: .. : :.: : : :: . .. : ..: : ..::: .:::.... . ...:
CCDS13 GQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTIC
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 GCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSP-NGTLEE
: : : .. : .: . . ::: :.. .: .::.:. :: : :: ....:.
CCDS13 TCEEGWHC---TSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEK
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 CQHQTKC---SWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIICVKRRKPRGDVV
:. :.: . .: .::.. .
CCDS13 CHPWTSCETKDLVVQQAGTNKTDVVCGPQDRLRALVVIPIIFGILFAILLVLVFIKKVAK
170 180 190 200 210 220
>>CCDS13394.1 CD40 gene_id:958|Hs108|chr20 (203 aa)
initn: 290 init1: 215 opt: 368 Z-score: 336.1 bits: 69.6 E(32554): 2.1e-12
Smith-Waterman score: 368; 32.5% identity (60.8% similar) in 166 aa overlap (21-184:6-166)
10 20 30 40 50
pF1KE1 MEPPGDWGPPPWRSTPRTDVLRLVLYLTFLGAPCYAPALPS-CKEDEYPVGSECCPKCSP
:. ::. .: : : :. :.: .: ..:.:: :.:
CCDS13 MVRLPLQCVLWGCLLTA--VHPEPPTACREKQYLINSQCCSLCQP
10 20 30 40
60 70 80 90 100 110
pF1KE1 GYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVC
: .. : :.: : : :: . .. : ..: : ..::: .:::.... . ...:
CCDS13 GQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTIC
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 GCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSP-NGTLEE
: : : .. : .: . . ::: :.. .: .::.:. :: : :: ....:.
CCDS13 TCEEGWHCT---SEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEK
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 CQHQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIICVKRRKPRGDVVKVI
:. :.
CCDS13 CHPWTRSPGSAESPGGDPHHLRDPVCHPLGAGLYQKGGQEANQ
170 180 190 200
>>CCDS145.1 TNFRSF1B gene_id:7133|Hs108|chr1 (461 aa)
initn: 347 init1: 206 opt: 366 Z-score: 330.3 bits: 69.7 E(32554): 4.4e-12
Smith-Waterman score: 366; 32.7% identity (58.2% similar) in 165 aa overlap (35-194:32-194)
10 20 30 40 50 60
pF1KE1 GDWGPPPWRSTPRTDVLRLVLYLTFLGAPCYAPALPS-CKEDEY--PVGSECCPKCSPGY
::: : :. :: ... :: :::::
CCDS14 APVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQC-QMCDPAMGLRASRNCSRTENAVCG
..: : . . :::. : .:: : . .::.: . :. . .. :.: .: .:
CCDS14 HAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQ--VETQACTREQNRICT
70 80 90 100 110
130 140 150 160 170
pF1KE1 CSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFS-PNGTLEEC
: :: .: .. . : : :: : . :::..:..:. : ::::: ... . :
CCDS14 CRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDIC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 QHQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIICVKRRKPRGDVVKVIV
. . :. .. ..:
CCDS14 RPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPST
180 190 200 210 220 230
>>CCDS13532.1 TNFRSF6B gene_id:8771|Hs108|chr20 (300 aa)
initn: 272 init1: 145 opt: 352 Z-score: 320.3 bits: 67.2 E(32554): 1.6e-11
Smith-Waterman score: 352; 34.7% identity (52.8% similar) in 193 aa overlap (16-200:7-189)
10 20 30 40 50
pF1KE1 MEPPGDWGPPPWRSTPRTDVLRLVLYL-TFLGAPCY--APALPSCKEDEYPVGSE-CCPK
: ..: ::: : ..: .: . :. . .: . : .
CCDS13 MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQ
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 CSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQ-MCDPAMGLRA--SRNCSR
: :: :.. : . . :.: :::: : : : .: :. .: : : .: :
CCDS13 CPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLC----GEREEEARACHA
60 70 80 90 100
120 130 140 150 160 170
pF1KE1 TENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPN
:.: .: : : : : . : .:. :: : :: ::.: :: ::::::: .
CCDS13 THNRACRCRTGFFA------HAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSAS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 GTL-EECQHQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIICVKRRKPRG
.. :.:: . .:. : .. ::::
CCDS13 SSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAF
170 180 190 200 210 220
>>CCDS59233.1 LTBR gene_id:4055|Hs108|chr12 (416 aa)
initn: 301 init1: 264 opt: 353 Z-score: 319.5 bits: 67.6 E(32554): 1.8e-11
Smith-Waterman score: 366; 26.4% identity (54.3% similar) in 254 aa overlap (30-261:12-262)
10 20 30 40 50
pF1KE1 MEPPGDWGPPPWRSTPRTDVLRLVLYLTFLGAPCYAPALPSCK--EDEY--PVGSECCPK
: .: :: .:. : :: : :: .
CCDS59 MEATGISLASQLKVPPYASENQTCRDQEKEYYEPQHRICCSR
10 20 30 40
60 70 80 90 100 110
pF1KE1 CSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTEN
: :: :. :... ::: : ..: : : :. : :. :::.:::. :. ..
CCDS59 CPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 AVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQ-KGGTESQDTLCQNCPPGTFSPNGT
. : :.:: :: . . :. :. . :: ... : . . .. : : : :. ...
CCDS59 TQCRCQPGMFCAAWALE-CTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSS
110 120 130 140 150 160
180 190 200 210 220
pF1KE1 -LEECQHQTKC-SWLVTKAGAGTSSSHW--------VWWFLSGSLVIVIVCSTVGLII--
.:: .:.: . ...:. ::..: . .::..... : .....
CCDS59 PSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLLL
170 180 190 200 210 220
230 240 250 260 270
pF1KE1 -----CVKRRKPRGDVVKVIVSVQRKRQEAEGEATVIEALQAPPDVTTVAVEETIPSFTG
:. . .: .. . . :. ..: ..:: : . . :
CCDS59 ATVFSCIWKSHP--SLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLPIS
230 240 250 260 270
280
pF1KE1 RSPNH
CCDS59 GDVSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHVTGGSMTIT
280 290 300 310 320 330
>>CCDS8544.1 LTBR gene_id:4055|Hs108|chr12 (435 aa)
initn: 301 init1: 264 opt: 350 Z-score: 316.7 bits: 67.1 E(32554): 2.5e-11
Smith-Waterman score: 367; 27.0% identity (52.7% similar) in 281 aa overlap (11-261:4-281)
10 20 30 40
pF1KE1 MEPPGDWGPPPW-RSTPRTDVLRLVLYLTFLGA-------PCYAPALPSCK--EDEY--P
:: :.: ::: : : : : :: .:. : :: :
CCDS85 MLLPWATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEP
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 VGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRAS
:: .: :: :. :... ::: : ..: : : :. : :. :::.:::.
CCDS85 QHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEI
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 RNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQ-KGGTESQDTLCQNCPP
:. ... : :.:: :: . . .:. :. . :: ... : . . .. : :
CCDS85 APCTSKRKTQCRCQPGMFCAAW-ALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKA
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 GTFSPNGT-LEECQHQTKC-SWLVTKAGAGTSSSHW--------VWWFLSGSLVIVIVCS
: :. ... .:: .:.: . ...:. ::..: . .::..... :
CCDS85 GHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 TVGLII-------CVKRRKPRGDVVKVIVSVQRKRQEAEGEATVIEALQAPPDVTTVAVE
..... :. . .: .. . . :. ..: ..:: : . . :
CCDS85 PLAFFLLLATVFSCIWKSHP--SLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDL
240 250 260 270 280 290
280
pF1KE1 ETIPSFTGRSPNH
CCDS85 VQPLLPISGDVSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHV
300 310 320 330 340 350
283 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:15:03 2016 done: Sun Nov 6 20:15:03 2016
Total Scan time: 2.660 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]