Result of FASTA (omim) for
pFN21AE1493
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1493, 292 aa
1>>>pF1KE1493 292 - 292 aa - 292 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3388+/-0.000561; mu= 14.9736+/- 0.034
mean_var=67.7253+/-14.149, 0's: 0 Z-trim(105.1): 144 B-trim: 38 in 1/47
Lambda= 0.155847
statistics sampled from 13204 (13353) to 13204 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.497), E-opt: 0.2 (0.157), width: 16
Scan time: 5.240
The best scores are: opt bits E(85289)
NP_861420 (OMIM: 600713,614662) corticosteroid 11- ( 292) 1858 427.5 1.5e-119
NP_005516 (OMIM: 600713,614662) corticosteroid 11- ( 292) 1858 427.5 1.5e-119
NP_001193670 (OMIM: 600713,614662) corticosteroid ( 292) 1858 427.5 1.5e-119
NP_057113 (OMIM: 612833) dehydrogenase/reductase S ( 339) 327 83.3 7.3e-16
XP_016876857 (OMIM: 612833) PREDICTED: dehydrogena ( 404) 327 83.3 8.4e-16
NP_057329 (OMIM: 612831) estradiol 17-beta-dehydro ( 300) 321 81.9 1.7e-15
NP_001309209 (OMIM: 612833) dehydrogenase/reductas ( 289) 319 81.4 2.2e-15
NP_001317088 (OMIM: 616160) dehydrogenase/reductas ( 310) 288 74.5 2.9e-13
NP_056325 (OMIM: 616160) dehydrogenase/reductase S ( 325) 288 74.5 3.1e-13
XP_016879915 (OMIM: 616160) PREDICTED: dehydrogena ( 325) 288 74.5 3.1e-13
XP_011522088 (OMIM: 616160) PREDICTED: dehydrogena ( 334) 288 74.5 3.1e-13
NP_066284 (OMIM: 611596) dehydrogenase/reductase S ( 278) 287 74.2 3.1e-13
XP_016879914 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 288 74.5 3.4e-13
XP_005256652 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 288 74.5 3.4e-13
NP_932349 (OMIM: 615196) dehydrogenase/reductase S ( 232) 271 70.6 3.3e-12
NP_835236 (OMIM: 612127) 17-beta-hydroxysteroid de ( 300) 266 69.5 8.8e-12
XP_005266734 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 298) 263 68.8 1.4e-11
NP_002026 (OMIM: 136440) 3-ketodihydrosphingosine ( 332) 263 68.9 1.5e-11
NP_005785 (OMIM: 615194) dehydrogenase/reductase S ( 280) 262 68.6 1.6e-11
XP_005267306 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 262 68.6 1.6e-11
XP_006720064 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 262 68.6 1.6e-11
NP_878912 (OMIM: 615194) dehydrogenase/reductase S ( 300) 260 68.2 2.2e-11
NP_001099041 (OMIM: 616161) dehydrogenase/reductas ( 311) 254 66.8 5.9e-11
XP_006720068 (OMIM: 611596) PREDICTED: dehydrogena ( 233) 248 65.4 1.2e-10
NP_057226 (OMIM: 609574) very-long-chain 3-oxoacyl ( 312) 248 65.5 1.5e-10
NP_001207422 (OMIM: 616161) dehydrogenase/reductas ( 312) 245 64.8 2.4e-10
XP_016873370 (OMIM: 609574) PREDICTED: very-long-c ( 280) 237 63.0 7.6e-10
NP_620419 (OMIM: 608989) epidermal retinol dehydro ( 309) 233 62.1 1.5e-09
NP_001304978 (OMIM: 608989) epidermal retinol dehy ( 318) 228 61.0 3.5e-09
NP_001276692 (OMIM: 612131) dehydrogenase/reductas ( 379) 225 60.4 6.4e-09
NP_001186700 (OMIM: 136880,601617) 11-cis retinol ( 318) 222 59.6 8.8e-09
NP_002896 (OMIM: 136880,601617) 11-cis retinol deh ( 318) 222 59.6 8.8e-09
XP_011508777 (OMIM: 612131) PREDICTED: dehydrogena ( 319) 219 59.0 1.4e-08
NP_001135742 (OMIM: 612131) dehydrogenase/reductas ( 319) 219 59.0 1.4e-08
NP_001135743 (OMIM: 612131) dehydrogenase/reductas ( 319) 219 59.0 1.4e-08
NP_954674 (OMIM: 612131) dehydrogenase/reductase S ( 319) 219 59.0 1.4e-08
XP_005269264 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 218 58.7 1.6e-08
XP_005269266 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 218 58.7 1.6e-08
XP_011537229 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 218 58.7 1.6e-08
XP_005269265 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 218 58.7 1.6e-08
XP_011537227 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 218 58.7 1.6e-08
XP_006719735 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 218 58.7 1.6e-08
XP_011537228 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 218 58.7 1.6e-08
NP_003716 (OMIM: 606623) 17-beta-hydroxysteroid de ( 317) 218 58.7 1.6e-08
NP_056540 (OMIM: 608575) retinol dehydrogenase 8 [ ( 331) 218 58.8 1.7e-08
NP_077284 (OMIM: 616159) dehydrogenase/reductase S ( 260) 208 56.4 6.6e-08
NP_004744 (OMIM: 612830) short-chain dehydrogenase ( 302) 202 55.1 1.9e-07
XP_016870165 (OMIM: 264300,605573) PREDICTED: test ( 238) 197 54.0 3.4e-07
XP_005257715 (OMIM: 616159) PREDICTED: dehydrogena ( 229) 196 53.7 3.9e-07
NP_000187 (OMIM: 218030,614232) corticosteroid 11- ( 405) 199 54.5 3.9e-07
>>NP_861420 (OMIM: 600713,614662) corticosteroid 11-beta (292 aa)
initn: 1858 init1: 1858 opt: 1858 Z-score: 2267.2 bits: 427.5 E(85289): 1.5e-119
Smith-Waterman score: 1858; 100.0% identity (100.0% similar) in 292 aa overlap (1-292:1-292)
10 20 30 40 50 60
pF1KE1 MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 AAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEE
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 CALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_861 CALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK
250 260 270 280 290
>>NP_005516 (OMIM: 600713,614662) corticosteroid 11-beta (292 aa)
initn: 1858 init1: 1858 opt: 1858 Z-score: 2267.2 bits: 427.5 E(85289): 1.5e-119
Smith-Waterman score: 1858; 100.0% identity (100.0% similar) in 292 aa overlap (1-292:1-292)
10 20 30 40 50 60
pF1KE1 MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEE
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 CALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK
250 260 270 280 290
>>NP_001193670 (OMIM: 600713,614662) corticosteroid 11-b (292 aa)
initn: 1858 init1: 1858 opt: 1858 Z-score: 2267.2 bits: 427.5 E(85289): 1.5e-119
Smith-Waterman score: 1858; 100.0% identity (100.0% similar) in 292 aa overlap (1-292:1-292)
10 20 30 40 50 60
pF1KE1 MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEE
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 CALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK
250 260 270 280 290
>>NP_057113 (OMIM: 612833) dehydrogenase/reductase SDR f (339 aa)
initn: 289 init1: 149 opt: 327 Z-score: 405.8 bits: 83.3 E(85289): 7.3e-16
Smith-Waterman score: 327; 33.8% identity (65.2% similar) in 210 aa overlap (28-231:43-250)
10 20 30 40 50
pF1KE1 MAFMKKYLLPILGLFMAYYYYSANEEFRPEM-LQGKKVIVTGASKGIGREMAYHLAK
::: : : :::::.:::.:.::.:.:
NP_057 CALLLLLVQLLRFLRADGDLTLLWAEWQGRRPEWELTDMVVWVTGASSGIGEELAYQLSK
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE1 MGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLM---GGL
.:. .:..:: . :..: .::: : . . : :.: . . : . .. : .
NP_057 LGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRI
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 DMLILNH-ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALP-MLKQSNGSIVVVSSL
:.:. : ... :: . .. :: .:.:.:. : :: .:: :.....:.::.:.:.
NP_057 DILVNNGGMSQRSLCM-DTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSI
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE1 AGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIV
: .. :. .: ::: :: :::...: : .. . ..: : .... . ....: :
NP_057 LGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICP-GPVQSNIVENSLAGEV
200 210 220 230 240 250
240 250 260 270 280 290
pF1KE1 HMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFIN
NP_057 TKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITN
260 270 280 290 300 310
>>XP_016876857 (OMIM: 612833) PREDICTED: dehydrogenase/r (404 aa)
initn: 311 init1: 149 opt: 327 Z-score: 404.7 bits: 83.3 E(85289): 8.4e-16
Smith-Waterman score: 327; 33.8% identity (65.2% similar) in 210 aa overlap (28-231:43-250)
10 20 30 40 50
pF1KE1 MAFMKKYLLPILGLFMAYYYYSANEEFRPEM-LQGKKVIVTGASKGIGREMAYHLAK
::: : : :::::.:::.:.::.:.:
XP_016 CALLLLLVQLLRFLRADGDLTLLWAEWQGRRPEWELTDMVVWVTGASSGIGEELAYQLSK
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE1 MGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLM---GGL
.:. .:..:: . :..: .::: : . . : :.: . . : . .. : .
XP_016 LGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRI
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 DMLILNH-ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALP-MLKQSNGSIVVVSSL
:.:. : ... :: . .. :: .:.:.:. : :: .:: :.....:.::.:.:.
XP_016 DILVNNGGMSQRSLCM-DTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSI
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE1 AGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIV
: .. :. .: ::: :: :::...: : .. . ..: : .... . ....: :
XP_016 LGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICP-GPVQSNIVENSLAGEV
200 210 220 230 240 250
240 250 260 270 280 290
pF1KE1 HMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFIN
XP_016 TKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITN
260 270 280 290 300 310
>>NP_057329 (OMIM: 612831) estradiol 17-beta-dehydrogena (300 aa)
initn: 262 init1: 185 opt: 321 Z-score: 399.3 bits: 81.9 E(85289): 1.7e-15
Smith-Waterman score: 321; 28.9% identity (59.1% similar) in 298 aa overlap (6-290:2-293)
10 20 30 40 50
pF1KE1 MAFMKKYLLPILGLFMAYYYYSANEEF-------RPEMLQGKKVIVTGASKGIGREMAYH
:.:: :: :.. . : : : . . :. :..:::..:::: ::.
NP_057 MKFLLDIL-LLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYE
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 LAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKL---M
.::. ...:. .:. :......: ::: ... : . :.. ..: :. .
NP_057 FAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVV----DCSNREDIYSSAKKVKAEI
60 70 80 90 100 110
120 130 140 150 160
pF1KE1 GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALP-MLKQSNGSIVVVS
: ...:. : . . .:: . ...:..::: :.. : : :: : :...: ::.:.
NP_057 GDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 SLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSG
: ::.:. :.. :: .:::: :: ... : .. ... : :. . . .: :
NP_057 SAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPST
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 IVHMQAAPKEECALEIIKGGALRQEEVYYDSSL-WTTLLIRN-PCRKILEFLYSTSYNMD
. : :: . ....: .:. .. ::. . : : : : : . . . : ..:
NP_057 SLGPTLEP-EEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFD
240 250 260 270 280 290
290
pF1KE1 RFINK
:
NP_057 AVIGYKMKAQ
300
>>NP_001309209 (OMIM: 612833) dehydrogenase/reductase SD (289 aa)
initn: 289 init1: 149 opt: 319 Z-score: 397.1 bits: 81.4 E(85289): 2.2e-15
Smith-Waterman score: 319; 33.5% identity (66.5% similar) in 200 aa overlap (37-231:3-200)
10 20 30 40 50 60
pF1KE1 YLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTAR
: :::::.:::.:.::.:.:.:. .:..::
NP_001 MVVWVTGASSGIGEELAYQLSKLGVSLVLSAR
10 20 30
70 80 90 100 110 120
pF1KE1 SKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLM---GGLDMLILNH-IT
. :..: .::: : . . : :.: . . : . .. : .:.:. : ..
NP_001 RVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 NTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALP-MLKQSNGSIVVVSSLAGKVAYPMVA
. :: . .. :: .:.:.:. : :: .:: :.....:.::.:.:. : .. :.
NP_001 QRSLCM-DTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 AYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEEC
.: ::: :: :::...: : .. . ..: : .... . ....: :
NP_001 GYCASKHALRGFFNGLRTELATYPGIIVSNICP-GPVQSNIVENSLAGEVTKTIGNNGDQ
160 170 180 190 200 210
250 260 270 280 290
pF1KE1 ALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK
NP_001 SHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQYMPTWAWWITNKMGKKRIENF
220 230 240 250 260 270
>>NP_001317088 (OMIM: 616160) dehydrogenase/reductase SD (310 aa)
initn: 222 init1: 110 opt: 288 Z-score: 359.0 bits: 74.5 E(85289): 2.9e-13
Smith-Waterman score: 289; 28.9% identity (62.9% similar) in 232 aa overlap (8-228:9-235)
10 20 30 40 50
pF1KE1 MAFMKKYLLPIL-GLFMAYYYYSANEEFRPE-MLQGKKVIVTGASKGIGREMAYHLAKM
.::.: : . .. . . : . .:.. :..:::..:.:.: : .
NP_001 MDFITSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 GAHVVVTARSKETLQKVVSHCLELGAASA-----HYIAGTMEDMTFAEQFVAQAGKLM--
::..:. .:. .:.... :: :. : : . :.: . .:: :....
NP_001 GAKLVLCGRNGGALEELIR---ELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQC
70 80 90 100 110
120 130 140 150 160
pF1KE1 -GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALP-MLKQSNGSIVVV
: .:.:. : . ... . .. ::.:... :.:: : :: :.:. .: ::..
NP_001 FGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAI
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 SSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVS
::. ::.. :. .::.::: : ..::. .: : . . .. .:. : : :. ...:..
NP_001 SSIQGKMSIPFRSAYAASKHATQAFFDCLRAE--MEQYEIEVTVISPGYIHTNLSVNAIT
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 GIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDR
NP_001 ADGSRYGVMDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFS
240 250 260 270 280 290
>>NP_056325 (OMIM: 616160) dehydrogenase/reductase SDR f (325 aa)
initn: 222 init1: 110 opt: 288 Z-score: 358.7 bits: 74.5 E(85289): 3.1e-13
Smith-Waterman score: 289; 28.9% identity (62.9% similar) in 232 aa overlap (8-228:24-250)
10 20 30 40
pF1KE1 MAFMKKYLLPIL-GLFMAYYYYSANEEFRPE-MLQGKKVIVTGA
.::.: : . .. . . : . .:.. :..:::
NP_056 MVSPATRKSLPKVKAMDFITSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGA
10 20 30 40 50 60
50 60 70 80 90
pF1KE1 SKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASA-----HYIAGTMEDMT
..:.:.: : . ::..:. .:. .:.... :: :. : : . :.:
NP_056 TSGLGKECAKVFYAAGAKLVLCGRNGGALEELIR---ELTASHATKVQTHKPYLVTFDLT
70 80 90 100 110
100 110 120 130 140 150
pF1KE1 FAEQFVAQAGKLM---GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAA
. .:: :.... : .:.:. : . ... . .. ::.:... :.:: :
NP_056 DSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKAL
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE1 LP-MLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLC
:: :.:. .: ::..::. ::.. :. .::.::: : ..::. .: : . . .. .:.
NP_056 LPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAE--MEQYEIEVTVI
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 VLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCR
: : :. ...:..
NP_056 SPGYIHTNLSVNAITADGSRYGVMDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPS
240 250 260 270 280 290
>>XP_016879915 (OMIM: 616160) PREDICTED: dehydrogenase/r (325 aa)
initn: 222 init1: 110 opt: 288 Z-score: 358.7 bits: 74.5 E(85289): 3.1e-13
Smith-Waterman score: 289; 28.9% identity (62.9% similar) in 232 aa overlap (8-228:24-250)
10 20 30 40
pF1KE1 MAFMKKYLLPIL-GLFMAYYYYSANEEFRPE-MLQGKKVIVTGA
.::.: : . .. . . : . .:.. :..:::
XP_016 MVSPATRKSLPKVKAMDFITSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGA
10 20 30 40 50 60
50 60 70 80 90
pF1KE1 SKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASA-----HYIAGTMEDMT
..:.:.: : . ::..:. .:. .:.... :: :. : : . :.:
XP_016 TSGLGKECAKVFYAAGAKLVLCGRNGGALEELIR---ELTASHATKVQTHKPYLVTFDLT
70 80 90 100 110
100 110 120 130 140 150
pF1KE1 FAEQFVAQAGKLM---GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAA
. .:: :.... : .:.:. : . ... . .. ::.:... :.:: :
XP_016 DSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKAL
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE1 LP-MLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLC
:: :.:. .: ::..::. ::.. :. .::.::: : ..::. .: : . . .. .:.
XP_016 LPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAE--MEQYEIEVTVI
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 VLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCR
: : :. ...:..
XP_016 SPGYIHTNLSVNAITADGSRYGVMDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPS
240 250 260 270 280 290
292 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:40:24 2016 done: Mon Nov 7 01:40:25 2016
Total Scan time: 5.240 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]