FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1489, 455 aa
  1>>>pF1KE1489 455 - 455 aa - 455 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.8114+/-0.000903; mu= 7.6622+/- 0.054
 mean_var=189.9039+/-37.680, 0's: 0 Z-trim(113.5): 41  B-trim: 66 in 2/51
 Lambda= 0.093069
 statistics sampled from 14075 (14111) to 14075 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.433), width:  16
 Scan time:  3.470

The best scores are:                                      opt bits E(32554)
CCDS8542.1 TNFRSF1A gene_id:7132|Hs108|chr12       ( 455) 3212 443.5 2.1e-124
CCDS72.1 TNFRSF25 gene_id:8718|Hs108|chr1          ( 426)  483 77.1   4e-14


>>CCDS8542.1 TNFRSF1A gene_id:7132|Hs108|chr12            (455 aa)
 initn: 3212 init1: 3212 opt: 3212  Z-score: 2347.1  bits: 443.5 E(32554): 2.1e-124
Smith-Waterman score: 3212; 100.0% identity (100.0% similar) in 455 aa overlap (1-455:1-455)

               10        20        30        40        50        60
pF1KE1 MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 KCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 RDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 RDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 SCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 SCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 SKLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 SKLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 PGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 PGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 AVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 AVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLEL
              370       380       390       400       410       420

              430       440       450     
pF1KE1 LGRVLRDMDLLGCLEDIEEALCGPAALPPAPSLLR
       :::::::::::::::::::::::::::::::::::
CCDS85 LGRVLRDMDLLGCLEDIEEALCGPAALPPAPSLLR
              430       440       450     

>>CCDS72.1 TNFRSF25 gene_id:8718|Hs108|chr1               (426 aa)
 initn: 415 init1: 132 opt: 483  Z-score: 367.1  bits: 77.1 E(32554): 4e-14
Smith-Waterman score: 538; 28.9% identity (50.8% similar) in 429 aa overlap (34-444:20-426)

            10        20        30           40        50        60
pF1KE1 STVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREK---RDSVCPQGKYIHPQNNSICCT
                                     :: : .   :.  :  .  .: . . .:: 
CCDS72            MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCR
                          10        20        30        40         

               70        80        90        100       110         
pF1KE1 KCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-HCLSCSKCRKEMGQVEISSCTV
        :  : ::   :  :  .. :  : . .: : :::   .:  :. : .. .:: . .:..
CCDS72 GCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSA
      50        60        70        80        90       100         

     120       130       140            150            160         
pF1KE1 DRDTVCGCRKNQYRHYWSENLFQC-----FNCSLCLN-GTVH----LSCQEKQNTVCTCH
         :: :::. . . .    .. ::     : :. ::. :..:    : :.....   :: 
CCDS72 VADTRCGCKPGWFVEC---QVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCL
     110       120          130       140       150       160      

     170       180       190       200       210       220         
pF1KE1 AGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLF
        ::. . . :::: .   ::  .     :     ..  . . :.   :.. :: .  :: 
CCDS72 PGFYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLG
        170       180       190       200       210       220      

     230       240       250       260       270       280         
pF1KE1 IGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVP
         : : :..         :    :   ..  :   . :.: :.   .:  .    ..: :
CCDS72 ATLTYTYRH---------CWPHKPLVTADEAG--MEALTPPPATHLSPLDSAHTLLAP-P
        230                240         250       260       270     

     290       300         310       320        330       340      
pF1KE1 SSTFTSSSTYTPGDC--PNFAAPRREVAPPYQGA-DPILATALASDPIPNPLQKWEDSAH
       .:.    ..   :.   :..   .. . :    . : . . ::.  :   :  . :. : 
CCDS72 DSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALG--PAAAPTLSPESPAG
          280       290       300       310         320       330  

        350       360       370       380       390       400      
pF1KE1 KPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLAT
       .:  .    :  :: :.. ::  ::::::: ::: . ::. .:.. :: .:. :: ::  
CCDS72 SPAMMLQPGPQ-LYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGR-FRDQQYEMLKR
            340        350       360       370        380       390

        410       420       430       440        450     
pF1KE1 WRRRTPRREATLELLGRVLRDMDLLGCLEDIEEALC-GPAALPPAPSLLR
       ::.. :   : :  .  .:. : : ::.::..  :  ::           
CCDS72 WRQQQP---AGLGAVYAALERMGLDGCVEDLRSRLQRGP           
                 400       410       420                 




455 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 01:57:41 2016 done: Mon Nov  7 01:57:41 2016
 Total Scan time:  3.470 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]