Result of FASTA (omim) for
pFN21AE1485
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1485, 423 aa
1>>>pF1KE1485 423 - 423 aa - 423 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5961+/-0.000465; mu= 15.3793+/- 0.029
mean_var=64.2431+/-13.074, 0's: 0 Z-trim(108.8): 46 B-trim: 0 in 0/50
Lambda= 0.160015
statistics sampled from 16872 (16914) to 16872 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.55), E-opt: 0.2 (0.198), width: 16
Scan time: 8.030
The best scores are: opt bits E(85289)
NP_001863 (OMIM: 603101) carboxypeptidase B2 isofo ( 423) 2845 666.0 4.9e-191
XP_016875882 (OMIM: 603101) PREDICTED: carboxypept ( 414) 2677 627.2 2.3e-179
NP_001265470 (OMIM: 603101) carboxypeptidase B2 is ( 386) 1319 313.7 5e-85
NP_001862 (OMIM: 114852) carboxypeptidase B prepro ( 417) 1155 275.9 1.3e-73
NP_001861 (OMIM: 114851) mast cell carboxypeptidas ( 417) 1121 268.0 3.1e-71
NP_065094 (OMIM: 609562,614417,614418) carboxypept ( 437) 1075 257.4 5.1e-68
NP_775100 (OMIM: 609563) carboxypeptidase O precur ( 374) 1028 246.6 8.1e-65
XP_016858861 (OMIM: 609563) PREDICTED: carboxypept ( 374) 1028 246.6 8.1e-65
XP_016869135 (OMIM: 609562,614417,614418) PREDICTE ( 289) 923 222.3 1.3e-57
XP_011515872 (OMIM: 609562,614417,614418) PREDICTE ( 289) 923 222.3 1.3e-57
NP_001860 (OMIM: 600688) carboxypeptidase A2 precu ( 419) 921 221.9 2.5e-57
NP_525124 (OMIM: 609561) carboxypeptidase A5 isofo ( 436) 904 217.9 3.9e-56
XP_011515000 (OMIM: 609561) PREDICTED: carboxypept ( 436) 904 217.9 3.9e-56
NP_001120913 (OMIM: 609561) carboxypeptidase A5 is ( 436) 904 217.9 3.9e-56
XP_011515005 (OMIM: 609561) PREDICTED: carboxypept ( 436) 904 217.9 3.9e-56
XP_011515004 (OMIM: 609561) PREDICTED: carboxypept ( 436) 904 217.9 3.9e-56
NP_001305152 (OMIM: 609561) carboxypeptidase A5 is ( 436) 904 217.9 3.9e-56
XP_005250769 (OMIM: 609561) PREDICTED: carboxypept ( 436) 904 217.9 3.9e-56
XP_011515003 (OMIM: 609561) PREDICTED: carboxypept ( 436) 904 217.9 3.9e-56
XP_005250767 (OMIM: 609561) PREDICTED: carboxypept ( 436) 904 217.9 3.9e-56
NP_001859 (OMIM: 114850) carboxypeptidase A1 prepr ( 419) 870 210.1 8.6e-54
NP_057436 (OMIM: 607635) carboxypeptidase A4 isofo ( 421) 865 208.9 1.9e-53
NP_001156918 (OMIM: 607635) carboxypeptidase A4 is ( 388) 789 191.4 3.4e-48
XP_011515006 (OMIM: 609561) PREDICTED: carboxypept ( 403) 674 164.8 3.5e-40
NP_001120914 (OMIM: 609561) carboxypeptidase A5 is ( 403) 674 164.8 3.5e-40
XP_011515007 (OMIM: 609561) PREDICTED: carboxypept ( 308) 504 125.6 1.8e-28
XP_016869136 (OMIM: 609562,614417,614418) PREDICTE ( 247) 386 98.3 2.3e-20
NP_001186704 (OMIM: 603102) carboxypeptidase D iso (1133) 176 50.0 3.6e-05
NP_001295 (OMIM: 603102) carboxypeptidase D isofor (1380) 176 50.1 4.2e-05
NP_001171628 (OMIM: 609555) probable carboxypeptid ( 660) 165 47.4 0.00013
NP_062555 (OMIM: 609555) probable carboxypeptidase ( 734) 165 47.4 0.00014
>>NP_001863 (OMIM: 603101) carboxypeptidase B2 isoform 1 (423 aa)
initn: 2845 init1: 2845 opt: 2845 Z-score: 3550.7 bits: 666.0 E(85289): 4.9e-191
Smith-Waterman score: 2845; 99.5% identity (99.5% similar) in 423 aa overlap (1-423:1-423)
10 20 30 40 50 60
pF1KE1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_001 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYTKPTCREAFAAVSKIAWHVI
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI
370 380 390 400 410 420
pF1KE1 RNV
:::
NP_001 RNV
>>XP_016875882 (OMIM: 603101) PREDICTED: carboxypeptidas (414 aa)
initn: 2677 init1: 2677 opt: 2677 Z-score: 3341.3 bits: 627.2 E(85289): 2.3e-179
Smith-Waterman score: 2677; 99.5% identity (99.5% similar) in 398 aa overlap (26-423:17-414)
10 20 30 40 50 60
pF1KE1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
:::::::::::::::::::::::::::::::::::
XP_016 MASPVPVESLEAGLACGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_016 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE1 TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYTKPTCREAFAAVSKIAWHVI
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_016 TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI
360 370 380 390 400 410
pF1KE1 RNV
:::
XP_016 RNV
>>NP_001265470 (OMIM: 603101) carboxypeptidase B2 isofor (386 aa)
initn: 2578 init1: 1319 opt: 1319 Z-score: 1647.5 bits: 313.7 E(85289): 5e-85
Smith-Waterman score: 2508; 90.8% identity (90.8% similar) in 423 aa overlap (1-423:1-386)
10 20 30 40 50 60
pF1KE1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK
::::::::::::::::: ::::::
NP_001 HAREWISPAFCLWFIGH-------------------------------------NRMWRK
190 200
250 260 270 280 290 300
pF1KE1 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE1 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_001 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSE
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE1 TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYTKPTCREAFAAVSKIAWHVI
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI
330 340 350 360 370 380
pF1KE1 RNV
:::
NP_001 RNV
>>NP_001862 (OMIM: 114852) carboxypeptidase B preproprot (417 aa)
initn: 1047 init1: 406 opt: 1155 Z-score: 1442.3 bits: 275.9 E(85289): 1.3e-73
Smith-Waterman score: 1155; 41.2% identity (73.9% similar) in 422 aa overlap (3-423:1-416)
10 20 30 40 50
pF1KE1 MKLCSLAVLVPIVLFCEQHVFA-FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTA
. .: ::: ..: .: :.. .:. . . .......:..: .: .:.: ..
NP_001 MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSV
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 DLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY
: .. : : :.: :. .:. :. . . .::......... :... . ::..
NP_001 TQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRV---RATGHS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCG
::.:.. . : .: . .. ..: .... ::..:: .:.::: :: : ::..:::
NP_001 YEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV-GKAGQNKPAIFMDCG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR
.::::::::::: ::. . .. :: : :.:: .::::.::.:.::: :.: :.:.::
NP_001 FHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 KNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRN
:.:: .... ::::: :::: . ::: ::: . :.::::: ::: :.::.:.:.: .
NP_001 KTRSTHTGSSCIGTDPNRNF-DAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 INQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGS
...::::...::::: ...::::. . .... ::. .:. .:. . . ..:.::.: :.
NP_001 LSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELA-SLHGTKYTYGPGA
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 ETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYTKPTCREAFAAVSKIAWHV
:.: : ::.::: :: ::.::::.:::::: ::::::: . ::.:.: :.. .: .:
NP_001 TTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYV
360 370 380 390 400 410
420
pF1KE1 IRNV
....
NP_001 LEHLY
>>NP_001861 (OMIM: 114851) mast cell carboxypeptidase A (417 aa)
initn: 855 init1: 424 opt: 1121 Z-score: 1399.9 bits: 268.0 E(85289): 3.1e-71
Smith-Waterman score: 1121; 40.1% identity (72.4% similar) in 421 aa overlap (6-422:1-415)
10 20 30 40 50
pF1KE1 MKLCSLAVLVPIVLFCEQHVFA---FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPV
. ...:. :. ..: :. .:. . :. .:......:. : :. .: :
NP_001 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQIS-NDTVSPRAS
.. .. . .: : :. .. . ... :. . . .:. :... :..:.. .. . : :
NP_001 ATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 ASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWI
: .:.. ..: .: : . ...:.:...:.:::. : ::::::. :... ..::.
NP_001 ---YAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKI-GEKNERRKAIFT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 DCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNR
:::::::::.::::: ::. . :. :: .:.:: ..::..:: ::::: .:: :::
NP_001 DCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 MWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFL
::::::: :..:::::::::: .. : ... :...: : :::: :.:::..:.
NP_001 MWRKNRSKNQNSKCIGTDLNRNFNAS-WNSIPNTNDPCADNYRGSAPESEKETKAVTNFI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 RRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHG
: ..:.::.::..::::: ..:::.:: . .::.:. ::. .. .. .: .::: .:
NP_001 RSHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVL-STRYETRYIYG
300 310 320 330 340
360 370 380 390 400 410
pF1KE1 HGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYTKPTCREAFAAVSKIA
:.: :.. :: ::::::..:..:::: : .:::::: ::::::.. ::. ::
NP_001 PIESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIA
350 360 370 380 390 400
420
pF1KE1 WHVIRNV
.....
NP_001 KYILKHTS
410
>>NP_065094 (OMIM: 609562,614417,614418) carboxypeptidas (437 aa)
initn: 1027 init1: 360 opt: 1075 Z-score: 1342.2 bits: 257.4 E(85289): 5.1e-68
Smith-Waterman score: 1075; 39.1% identity (68.2% similar) in 425 aa overlap (1-421:15-434)
10 20 30 40
pF1KE1 MKLCSLAVLVPIVLFCEQHVFA--FQSGQVLAALPRTSRQVQVLQN
. :: : .. :. ..:.. . . .:. .:.: ... .:..
NP_065 MKCLGKRRGQAAAFLPLCWL--FLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKK
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 LTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQ
.. .. :::: . . . . . . . . : :. ..: .::. :.. ...
NP_065 ISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 QISNDTVSPRASAS-Y-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLK
: : : : : : :: ::::.:: .:.. ... : .. . :: :.: :..::
NP_065 GSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 VSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPV
. :... : :.::::::::::::.:::: ::. . : . ..: . ::.:::
NP_065 L-GRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 VNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLY
::::: .:: ..:.:::.:: . .: :.: :::. : ::.:::: :..:::: .
NP_065 FNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVK-WCDEGASMHPCDDTYCGPF
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 PESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVR
:::::::::::.:::.. ..:.::.:.:.:.: ...:::: . . . . .: .::
NP_065 PESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVN
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 AIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYTK
:.... ..:: .: .: :::.. :.. :: : :: :.:..:::::: .:::::: :
NP_065 ALQSVY-GVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIK
360 370 380 390 400 410
410 420
pF1KE1 PTCREAFAAVSKIAWHVIRNV
::: :.. ::..:. :...
NP_065 PTCTETMLAVKNITMHLLKKCP
420 430
>>NP_775100 (OMIM: 609563) carboxypeptidase O precursor (374 aa)
initn: 964 init1: 539 opt: 1028 Z-score: 1284.6 bits: 246.6 E(85289): 8.1e-65
Smith-Waterman score: 1028; 45.9% identity (75.5% similar) in 314 aa overlap (103-415:29-340)
80 90 100 110 120 130
pF1KE1 NASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY-YEQYHSLNEIYS
.:.: . .::: . .: :. :: ..:::
NP_775 MKPLLETLYLLGMLVPGGLGYDRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYE
10 20 30 40 50
140 150 160 170 180 190
pF1KE1 WIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFC
:.. :.:.. ...:. .: ..: .:.: ::.: :. ::.::::::::::.::::
NP_775 WMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFC
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE1 LWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCI
::. .: : . .. .::: .::::.::.:.::: :.: .:.:::.:: . :. :.
NP_775 QWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCF
120 130 140 150 160 170
260 270 280 290 300 310
pF1KE1 GTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHS
:::::::: .. :: ::: . ..:.:: : ::::.::::::.. . ..: ...:::
NP_775 GTDLNRNFNAS-WCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHS
180 190 200 210 220 230
320 330 340 350 360 370
pF1KE1 YSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDD
:.: :. ::.::..::..: :. :...:. :. :.. .: : : ... :: . :.. :
NP_775 YGQLILTPYGYTKNKSSNHPEMIQVGQKAANAL-KAKYGTNYRVGSSADILYASSGSSRD
240 250 260 270 280 290
380 390 400 410 420
pF1KE1 WIYDLGIKYSFTIELRDTGTYGFLLPERYTKPTCREAFAAVSKIAWHVIRNV
: :.:: .:.:.::::.:::::.::: .:::.:.. :: ..
NP_775 WARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDVYAKHWHSDSAGR
300 310 320 330 340 350
NP_775 VTSATMLLGLLVSCMSLL
360 370
>>XP_016858861 (OMIM: 609563) PREDICTED: carboxypeptidas (374 aa)
initn: 964 init1: 539 opt: 1028 Z-score: 1284.6 bits: 246.6 E(85289): 8.1e-65
Smith-Waterman score: 1028; 45.9% identity (75.5% similar) in 314 aa overlap (103-415:29-340)
80 90 100 110 120 130
pF1KE1 NASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY-YEQYHSLNEIYS
.:.: . .::: . .: :. :: ..:::
XP_016 MKPLLETLYLLGMLVPGGLGYDRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYE
10 20 30 40 50
140 150 160 170 180 190
pF1KE1 WIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFC
:.. :.:.. ...:. .: ..: .:.: ::.: :. ::.::::::::::.::::
XP_016 WMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFC
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE1 LWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCI
::. .: : . .. .::: .::::.::.:.::: :.: .:.:::.:: . :. :.
XP_016 QWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCF
120 130 140 150 160 170
260 270 280 290 300 310
pF1KE1 GTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHS
:::::::: .. :: ::: . ..:.:: : ::::.::::::.. . ..: ...:::
XP_016 GTDLNRNFNAS-WCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHS
180 190 200 210 220 230
320 330 340 350 360 370
pF1KE1 YSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDD
:.: :. ::.::..::..: :. :...:. :. :.. .: : : ... :: . :.. :
XP_016 YGQLILTPYGYTKNKSSNHPEMIQVGQKAANAL-KAKYGTNYRVGSSADILYASSGSSRD
240 250 260 270 280 290
380 390 400 410 420
pF1KE1 WIYDLGIKYSFTIELRDTGTYGFLLPERYTKPTCREAFAAVSKIAWHVIRNV
: :.:: .:.:.::::.:::::.::: .:::.:.. :: ..
XP_016 WARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDVYAKHWHSDSAGR
300 310 320 330 340 350
XP_016 VTSATMLLGLLVSCMSLL
360 370
>>XP_016869135 (OMIM: 609562,614417,614418) PREDICTED: c (289 aa)
initn: 874 init1: 360 opt: 923 Z-score: 1155.4 bits: 222.3 E(85289): 1.3e-57
Smith-Waterman score: 923; 45.7% identity (73.4% similar) in 289 aa overlap (133-421:1-286)
110 120 130 140 150 160
pF1KE1 QQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLK
.. ... : .. . :: :.: :..::
XP_016 MHHLNKTHSGLIHMFSIGRSYEGRSLFILK
10 20 30
170 180 190 200 210 220
pF1KE1 VSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPV
. :... : :.::::::::::::.:::: ::. . : . ..: . ::.:::
XP_016 L-GRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPV
40 50 60 70 80
230 240 250 260 270 280
pF1KE1 VNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLY
::::: .:: ..:.:::.:: . .: :.: :::. : ::.:::: :..:::: .
XP_016 FNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVK-WCDEGASMHPCDDTYCGPF
90 100 110 120 130 140
290 300 310 320 330 340
pF1KE1 PESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVR
:::::::::::.:::.. ..:.::.:.:.:.: ...:::: . . . . .: .::
XP_016 PESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVN
150 160 170 180 190 200
350 360 370 380 390 400
pF1KE1 AIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYTK
:.... ..:: .: .: :::.. :.. :: : :: :.:..:::::: .:::::: :
XP_016 ALQSVY-GVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIK
210 220 230 240 250 260
410 420
pF1KE1 PTCREAFAAVSKIAWHVIRNV
::: :.. ::..:. :...
XP_016 PTCTETMLAVKNITMHLLKKCP
270 280
>>XP_011515872 (OMIM: 609562,614417,614418) PREDICTED: c (289 aa)
initn: 874 init1: 360 opt: 923 Z-score: 1155.4 bits: 222.3 E(85289): 1.3e-57
Smith-Waterman score: 923; 45.7% identity (73.4% similar) in 289 aa overlap (133-421:1-286)
110 120 130 140 150 160
pF1KE1 QQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLK
.. ... : .. . :: :.: :..::
XP_011 MHHLNKTHSGLIHMFSIGRSYEGRSLFILK
10 20 30
170 180 190 200 210 220
pF1KE1 VSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPV
. :... : :.::::::::::::.:::: ::. . : . ..: . ::.:::
XP_011 L-GRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPV
40 50 60 70 80
230 240 250 260 270 280
pF1KE1 VNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLY
::::: .:: ..:.:::.:: . .: :.: :::. : ::.:::: :..:::: .
XP_011 FNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVK-WCDEGASMHPCDDTYCGPF
90 100 110 120 130 140
290 300 310 320 330 340
pF1KE1 PESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVR
:::::::::::.:::.. ..:.::.:.:.:.: ...:::: . . . . .: .::
XP_011 PESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVN
150 160 170 180 190 200
350 360 370 380 390 400
pF1KE1 AIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYTK
:.... ..:: .: .: :::.. :.. :: : :: :.:..:::::: .:::::: :
XP_011 ALQSVY-GVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIK
210 220 230 240 250 260
410 420
pF1KE1 PTCREAFAAVSKIAWHVIRNV
::: :.. ::..:. :...
XP_011 PTCTETMLAVKNITMHLLKKCP
270 280
423 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:14:28 2016 done: Mon Nov 7 02:14:30 2016
Total Scan time: 8.030 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]