Result of FASTA (omim) for
pFN21AE1474
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1474, 502 aa
1>>>pF1KE1474 502 - 502 aa - 502 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9987+/-0.000385; mu= 19.7210+/- 0.024
mean_var=63.6071+/-13.025, 0's: 0 Z-trim(112.5): 20 B-trim: 584 in 1/49
Lambda= 0.160813
statistics sampled from 21408 (21425) to 21408 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.251), width: 16
Scan time: 8.360
The best scores are: opt bits E(85289)
NP_061195 (OMIM: 605458) interleukin-17 receptor B ( 502) 3442 807.5 0
XP_016862295 (OMIM: 605458) PREDICTED: interleukin ( 385) 2654 624.6 1.5e-178
XP_005265369 (OMIM: 605458) PREDICTED: interleukin ( 486) 2244 529.6 7.9e-150
XP_016862296 (OMIM: 605458) PREDICTED: interleukin ( 328) 2163 510.7 2.6e-144
XP_016862294 (OMIM: 605458) PREDICTED: interleukin ( 398) 1765 418.4 1.9e-116
XP_016862293 (OMIM: 605458) PREDICTED: interleukin ( 414) 1765 418.4 2e-116
XP_005265368 (OMIM: 605458) PREDICTED: interleukin ( 515) 1765 418.5 2.3e-116
XP_005265367 (OMIM: 605458) PREDICTED: interleukin ( 531) 1765 418.5 2.4e-116
XP_011532243 (OMIM: 605458) PREDICTED: interleukin ( 357) 1677 398.0 2.4e-110
NP_001276834 (OMIM: 605461,613953) interleukin-17 ( 832) 337 87.3 1.9e-16
NP_055154 (OMIM: 605461,613953) interleukin-17 rec ( 866) 302 79.2 5.3e-14
XP_011532151 (OMIM: 606807,615267) PREDICTED: inte ( 595) 175 49.6 2.9e-05
XP_006713272 (OMIM: 606807,615267) PREDICTED: inte ( 595) 175 49.6 2.9e-05
NP_001305793 (OMIM: 606807,615267) interleukin-17 ( 595) 175 49.6 2.9e-05
XP_005265295 (OMIM: 606807,615267) PREDICTED: inte ( 711) 175 49.7 3.4e-05
NP_060033 (OMIM: 606807,615267) interleukin-17 rec ( 739) 175 49.7 3.5e-05
>>NP_061195 (OMIM: 605458) interleukin-17 receptor B pre (502 aa)
initn: 3442 init1: 3442 opt: 3442 Z-score: 4312.8 bits: 807.5 E(85289): 0
Smith-Waterman score: 3442; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)
10 20 30 40 50 60
pF1KE1 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 DLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELL
430 440 450 460 470 480
490 500
pF1KE1 HVKQQVSAGKRSQACHDGCCSL
::::::::::::::::::::::
NP_061 HVKQQVSAGKRSQACHDGCCSL
490 500
>>XP_016862295 (OMIM: 605458) PREDICTED: interleukin-17 (385 aa)
initn: 2654 init1: 2654 opt: 2654 Z-score: 3326.5 bits: 624.6 E(85289): 1.5e-178
Smith-Waterman score: 2654; 100.0% identity (100.0% similar) in 384 aa overlap (119-502:2-385)
90 100 110 120 130 140
pF1KE1 TGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNE
::::::::::::::::::::::::::::::
XP_016 MWTFSYIGFPVELNTVYFIGAHNIPNANMNE
10 20 30
150 160 170 180 190 200
pF1KE1 DGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYM
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE1 ALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQLTPYFPTCGSDCIRHKGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQLTPYFPTCGSDCIRHKGTV
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE1 VLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTL
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE1 LPPIKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPIKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKA
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE1 ADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYF
280 290 300 310 320 330
450 460 470 480 490 500
pF1KE1 REIDTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REIDTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
340 350 360 370 380
>>XP_005265369 (OMIM: 605458) PREDICTED: interleukin-17 (486 aa)
initn: 2244 init1: 2244 opt: 2244 Z-score: 2810.9 bits: 529.6 E(85289): 7.9e-150
Smith-Waterman score: 3283; 96.8% identity (96.8% similar) in 502 aa overlap (1-502:1-486)
10 20 30 40 50 60
pF1KE1 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
::::::::::::::::::::::::::::::::::::::::: :::
XP_005 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPG----------------SLW
130 140 150 160
190 200 210 220 230 240
pF1KE1 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 GDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 ATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCR
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE1 SEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQ
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE1 DLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELL
410 420 430 440 450 460
490 500
pF1KE1 HVKQQVSAGKRSQACHDGCCSL
::::::::::::::::::::::
XP_005 HVKQQVSAGKRSQACHDGCCSL
470 480
>>XP_016862296 (OMIM: 605458) PREDICTED: interleukin-17 (328 aa)
initn: 2163 init1: 2163 opt: 2163 Z-score: 2711.8 bits: 510.7 E(85289): 2.6e-144
Smith-Waterman score: 2163; 100.0% identity (100.0% similar) in 316 aa overlap (1-316:1-316)
10 20 30 40 50 60
pF1KE1 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCR
::::::::::::::::
XP_016 ATWVLVAGIYLMWRHEVRSSLKSGRKRK
310 320
>>XP_016862294 (OMIM: 605458) PREDICTED: interleukin-17 (398 aa)
initn: 2230 init1: 1765 opt: 1765 Z-score: 2211.6 bits: 418.4 E(85289): 1.9e-116
Smith-Waterman score: 2427; 89.1% identity (89.1% similar) in 413 aa overlap (119-502:2-398)
90 100 110 120 130 140
pF1KE1 TGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNE
::::::::::::::::::::::::::::::
XP_016 MWTFSYIGFPVELNTVYFIGAHNIPNANMNE
10 20 30
150 160 170 180 190 200
pF1KE1 DGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYM
::::::::::::: :::::::::::::::::::::::::::::::
XP_016 DGPSMSVNFTSPG----------------SLWDPNITACKKNEETVEVNFTTTPLGNRYM
40 50 60 70
210 220 230 240
pF1KE1 ALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQ-------------------
:::::::::::::::::::::::::::::::::::::::::
XP_016 ALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQGLACPKALAEGSQEDHCCS
80 90 100 110 120 130
250 260 270 280 290
pF1KE1 ----------LTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLL
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFLEEMFVYVLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLL
140 150 160 170 180 190
300 310 320 330 340 350
pF1KE1 VATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHC
200 210 220 230 240 250
360 370 380 390 400 410
pF1KE1 RSEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENS
260 270 280 290 300 310
420 430 440 450 460 470
pF1KE1 QDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAEL
320 330 340 350 360 370
480 490 500
pF1KE1 LHVKQQVSAGKRSQACHDGCCSL
:::::::::::::::::::::::
XP_016 LHVKQQVSAGKRSQACHDGCCSL
380 390
>>XP_016862293 (OMIM: 605458) PREDICTED: interleukin-17 (414 aa)
initn: 2640 init1: 1765 opt: 1765 Z-score: 2211.3 bits: 418.4 E(85289): 2e-116
Smith-Waterman score: 2586; 93.0% identity (93.0% similar) in 413 aa overlap (119-502:2-414)
90 100 110 120 130 140
pF1KE1 TGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNE
::::::::::::::::::::::::::::::
XP_016 MWTFSYIGFPVELNTVYFIGAHNIPNANMNE
10 20 30
150 160 170 180 190 200
pF1KE1 DGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYM
40 50 60 70 80 90
210 220 230 240
pF1KE1 ALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQ-------------------
:::::::::::::::::::::::::::::::::::::::::
XP_016 ALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQGLACPKALAEGSQEDHCCS
100 110 120 130 140 150
250 260 270 280 290
pF1KE1 ----------LTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLL
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFLEEMFVYVLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLL
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE1 VATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHC
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE1 RSEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENS
280 290 300 310 320 330
420 430 440 450 460 470
pF1KE1 QDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAEL
340 350 360 370 380 390
480 490 500
pF1KE1 LHVKQQVSAGKRSQACHDGCCSL
:::::::::::::::::::::::
XP_016 LHVKQQVSAGKRSQACHDGCCSL
400 410
>>XP_005265368 (OMIM: 605458) PREDICTED: interleukin-17 (515 aa)
initn: 2844 init1: 1765 opt: 1765 Z-score: 2210.0 bits: 418.5 E(85289): 2.3e-116
Smith-Waterman score: 3215; 91.5% identity (91.5% similar) in 531 aa overlap (1-502:1-515)
10 20 30 40 50 60
pF1KE1 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
::::::::::::::::::::::::::::::::::::::::: :::
XP_005 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPG----------------SLW
130 140 150 160
190 200 210 220 230 240
pF1KE1 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
170 180 190 200 210 220
250 260 270
pF1KE1 GDSEGATVQ-----------------------------LTPYFPTCGSDCIRHKGTVVLC
::::::::: ::::::::::::::::::::::
XP_005 GDSEGATVQGLACPKALAEGSQEDHCCSFFLEEMFVYVLTPYFPTCGSDCIRHKGTVVLC
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE1 PQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTLLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTLLPP
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE1 IKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADK
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE1 VVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREI
410 420 430 440 450 460
460 470 480 490 500
pF1KE1 DTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
470 480 490 500 510
>>XP_005265367 (OMIM: 605458) PREDICTED: interleukin-17 (531 aa)
initn: 3428 init1: 1765 opt: 1765 Z-score: 2209.8 bits: 418.5 E(85289): 2.4e-116
Smith-Waterman score: 3374; 94.5% identity (94.5% similar) in 531 aa overlap (1-502:1-531)
10 20 30 40 50 60
pF1KE1 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
190 200 210 220 230 240
250 260 270
pF1KE1 GDSEGATVQ-----------------------------LTPYFPTCGSDCIRHKGTVVLC
::::::::: ::::::::::::::::::::::
XP_005 GDSEGATVQGLACPKALAEGSQEDHCCSFFLEEMFVYVLTPYFPTCGSDCIRHKGTVVLC
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE1 PQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTLLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTLLPP
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE1 IKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADK
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE1 VVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREI
430 440 450 460 470 480
460 470 480 490 500
pF1KE1 DTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
490 500 510 520 530
>>XP_011532243 (OMIM: 605458) PREDICTED: interleukin-17 (357 aa)
initn: 2149 init1: 1677 opt: 1677 Z-score: 2101.9 bits: 398.0 E(85289): 2.4e-110
Smith-Waterman score: 2095; 91.6% identity (91.6% similar) in 345 aa overlap (1-316:1-345)
10 20 30 40 50 60
pF1KE1 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVT
190 200 210 220 230 240
250 260 270
pF1KE1 GDSEGATVQ-----------------------------LTPYFPTCGSDCIRHKGTVVLC
::::::::: ::::::::::::::::::::::
XP_011 GDSEGATVQGLACPKALAEGSQEDHCCSFFLEEMFVYVLTPYFPTCGSDCIRHKGTVVLC
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE1 PQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTLLPP
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHEVRSSLKSGRKRK
310 320 330 340 350
340 350 360 370 380 390
pF1KE1 IKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADK
>>NP_001276834 (OMIM: 605461,613953) interleukin-17 rece (832 aa)
initn: 342 init1: 134 opt: 337 Z-score: 416.5 bits: 87.3 E(85289): 1.9e-16
Smith-Waterman score: 507; 24.8% identity (53.5% similar) in 488 aa overlap (13-469:39-492)
10 20 30 40
pF1KE1 MSLVLLSLAALCRSAVPREPTVQCGSETGP--SPEWMLQHDL
:. : .: ..: ... . :. ..:
NP_001 SAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 IPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCV
:.. .::... . . :: . .. :.:..:::: :..... : . : . ::
NP_001 TPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVL-QLNTNERLCV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 RCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSP
: . : .. : .: :.. : :. . : . .:..:. . : .: :: :
NP_001 RFE----FLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVP
130 140 150 160 170 180
170 180 190 200 210
pF1KE1 GCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALI-------QH
: :: :...:::::::::. . . ..:.:: ...:. :. .:
NP_001 DCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENH
190 200 210 220 230 240
220 230 240 250 260
pF1KE1 STIIGFSQVFEPHQKK-QTRASVVIPVTGDSEGAT---VQLTPYFPTCGSDCIRHKGTVV
: . . .. :. .. . :..:.. . . .: ::. :.: .: .::.::..::
NP_001 SCFEHMHHIPAPRPEEFHQRSNVTLTLR-NLKGCCRHQVQIQPFFSSCLNDCLRHSATVS
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE1 LCPQT-GVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTL
::. .: :. . ::. . . .. .. :
NP_001 -CPEMPDTPEPIPG----PGSE---------------------KYSDDTKYTDGLPAADL
310 320 330
330 340 350 360 370 380
pF1KE1 LPPI----KVLVVYPSEICFH-HTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLA
.:: :: ..: .. .. .. :..:: . : .:: :. ... :.: : . :..
NP_001 IPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVG
340 350 360 370 380 390
390 400 410 420 430
pF1KE1 TQKK----AADKVVFLLSNDVNSVCDGTCGKSEGSP-------SENSQDLFPLAFNLFCS
::. . .:.. : : . . .. :. :.: .. ::: :.:..
NP_001 RQKQEMVESNSKIIVLCSRGTRAKWQALLGR--GAPVRLRCDHGKPVGDLFTAAMNMILP
400 410 420 430 440 450
440 450 460 470 480 490
pF1KE1 DLRSQIHLHKYVVVYFREIDTKDDYNAL-SVCPKYHLMKDATAFCAELLHVKQQVSAGKR
:.. . ::: :: :.. : : .. :.: ::
NP_001 DFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLEMFQPGRMH
460 470 480 490 500 510
500
pF1KE1 SQACHDGCCSL
NP_001 RVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPSLDEEVFEE
520 530 540 550 560 570
502 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:42:51 2016 done: Mon Nov 7 15:42:52 2016
Total Scan time: 8.360 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]